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The map label for this gene is qmcA [H]

Identifier: 213157701

GI number: 213157701

Start: 3306361

End: 3307215

Strand: Direct

Name: qmcA [H]

Synonym: AB57_3180

Alternate gene names: 213157701

Gene position: 3306361-3307215 (Clockwise)

Preceding gene: 213157700

Following gene: 213157705

Centisome position: 81.63

GC content: 39.53

Gene sequence:

>855_bases
ATGCCAGTTGGTACTATTATTGTTTTAGCCTTTTTGGCTTTTGTTGCTGTTACCATTTTTAAAGGGGTACGTATTGTTCC
TCAAGGTTATAAATGGATTGTTCAGCGTTTAGGAAAATATCATTCTACGCTTAATCCTGGGCTTAACTTCGTTATTCCTT
ATATTGATGATGTAGCCTATAAAGTCACCACTAAAGATATTGTGCTTGATATTCCATCACAAGAAGTCATTACCCGTGAC
AATGCTGTATTACTCATGAATGCCGTTGCGTATATCAATCTGACTACACCTGAAAAAGCGGTGTACGGTATTGAAAACTA
TACATGGGCCATTCAGAACCTTGTACAGACTTCACTACGTTCAATTGTCGGTGAAATGGATCTAGATGATGCCCTATCTT
CACGAGATCACATTAAAGCTAAACTAAAAGCTGCGATTTCTGATGATATTTCAGATTGGGGTATCACTTTAAAAACAGTA
GAAATTCAAGATATTCAGCCATCTTCAACCATGCAAGCTGCCATGGAAGCTCAAGCCGCTGCTGAACGTCAACGTCGTGC
TACAGTTACCAAAGCTGATGGTGAGAAACAAGCTGCAATTTTAGAAGCAGATGGTCGTTTAGAAGCATCTCGCCGTGATG
CCGAAGCTCAGGTTGTTTTAGCAGAAGCTTCTCAAAAAGCGATTGAAATGGTAACAAGTGCCGTAGGTGATAAAGAAATT
CCTGTTGCTTACCTGTTAGGTGAACAATACGTCAAAGCAATGCAAGAGATGGCGAAATCAAGCAATGCTAAAACTGTTGT
GTTACCTGCCGATGTTTTAAATACCATACGTGGCATTATGGGAAAGCATAATTAA

Upstream 100 bases:

>100_bases
GTCGGTGATCGGGTTCGAGTCATTGATATTTCGGGTAATGACTTAATTGTTCAGCCCCACAGCACTTCATAAACATTAAA
GATAAAGAGAGGTTATTTTC

Downstream 100 bases:

>100_bases
TTTAATTGCTTCAAATAAGACATTGAAATAAAACGGTGACAATCATGTCGCCGTTTTTCTTTTATATTATTGGTTGTTTA
ATCTTTTCTGATCTTTCAAA

Product: band 7 protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 284; Mature: 283

Protein sequence:

>284_residues
MPVGTIIVLAFLAFVAVTIFKGVRIVPQGYKWIVQRLGKYHSTLNPGLNFVIPYIDDVAYKVTTKDIVLDIPSQEVITRD
NAVLLMNAVAYINLTTPEKAVYGIENYTWAIQNLVQTSLRSIVGEMDLDDALSSRDHIKAKLKAAISDDISDWGITLKTV
EIQDIQPSSTMQAAMEAQAAAERQRRATVTKADGEKQAAILEADGRLEASRRDAEAQVVLAEASQKAIEMVTSAVGDKEI
PVAYLLGEQYVKAMQEMAKSSNAKTVVLPADVLNTIRGIMGKHN

Sequences:

>Translated_284_residues
MPVGTIIVLAFLAFVAVTIFKGVRIVPQGYKWIVQRLGKYHSTLNPGLNFVIPYIDDVAYKVTTKDIVLDIPSQEVITRD
NAVLLMNAVAYINLTTPEKAVYGIENYTWAIQNLVQTSLRSIVGEMDLDDALSSRDHIKAKLKAAISDDISDWGITLKTV
EIQDIQPSSTMQAAMEAQAAAERQRRATVTKADGEKQAAILEADGRLEASRRDAEAQVVLAEASQKAIEMVTSAVGDKEI
PVAYLLGEQYVKAMQEMAKSSNAKTVVLPADVLNTIRGIMGKHN
>Mature_283_residues
PVGTIIVLAFLAFVAVTIFKGVRIVPQGYKWIVQRLGKYHSTLNPGLNFVIPYIDDVAYKVTTKDIVLDIPSQEVITRDN
AVLLMNAVAYINLTTPEKAVYGIENYTWAIQNLVQTSLRSIVGEMDLDDALSSRDHIKAKLKAAISDDISDWGITLKTVE
IQDIQPSSTMQAAMEAQAAAERQRRATVTKADGEKQAAILEADGRLEASRRDAEAQVVLAEASQKAIEMVTSAVGDKEIP
VAYLLGEQYVKAMQEMAKSSNAKTVVLPADVLNTIRGIMGKHN

Specific function: Unknown

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family [H]

Homologues:

Organism=Homo sapiens, GI7305503, Length=288, Percent_Identity=32.2916666666667, Blast_Score=160, Evalue=1e-39,
Organism=Homo sapiens, GI38016911, Length=290, Percent_Identity=30.3448275862069, Blast_Score=101, Evalue=7e-22,
Organism=Homo sapiens, GI221316744, Length=277, Percent_Identity=28.8808664259928, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI21686995, Length=277, Percent_Identity=28.8808664259928, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI7657615, Length=185, Percent_Identity=27.5675675675676, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1786697, Length=290, Percent_Identity=38.9655172413793, Blast_Score=221, Evalue=3e-59,
Organism=Escherichia coli, GI1790616, Length=220, Percent_Identity=24.0909090909091, Blast_Score=61, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI32564147, Length=270, Percent_Identity=36.2962962962963, Blast_Score=168, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI17569493, Length=189, Percent_Identity=35.4497354497354, Blast_Score=118, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI193209764, Length=189, Percent_Identity=35.4497354497354, Blast_Score=117, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI17569497, Length=202, Percent_Identity=31.1881188118812, Blast_Score=97, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI17570459, Length=194, Percent_Identity=29.3814432989691, Blast_Score=94, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17569499, Length=199, Percent_Identity=30.1507537688442, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71989955, Length=184, Percent_Identity=31.5217391304348, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71989948, Length=184, Percent_Identity=31.5217391304348, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI32566490, Length=185, Percent_Identity=30.8108108108108, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71987612, Length=198, Percent_Identity=27.7777777777778, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71987621, Length=203, Percent_Identity=29.064039408867, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI25153583, Length=198, Percent_Identity=27.7777777777778, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17542664, Length=167, Percent_Identity=28.1437125748503, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17570161, Length=196, Percent_Identity=26.0204081632653, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI193210507, Length=196, Percent_Identity=26.0204081632653, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71989963, Length=135, Percent_Identity=31.1111111111111, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI45550506, Length=268, Percent_Identity=32.4626865671642, Blast_Score=155, Evalue=3e-38,
Organism=Drosophila melanogaster, GI18860517, Length=193, Percent_Identity=33.160621761658, Blast_Score=104, Evalue=7e-23,
Organism=Drosophila melanogaster, GI45556022, Length=209, Percent_Identity=31.5789473684211, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI281361631, Length=244, Percent_Identity=26.6393442622951, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI281361633, Length=244, Percent_Identity=26.6393442622951, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI21356845, Length=197, Percent_Identity=27.9187817258883, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI28573263, Length=199, Percent_Identity=27.6381909547739, Blast_Score=94, Evalue=8e-20,
Organism=Drosophila melanogaster, GI62484274, Length=203, Percent_Identity=30.0492610837438, Blast_Score=87, Evalue=9e-18,
Organism=Drosophila melanogaster, GI62484448, Length=203, Percent_Identity=30.0492610837438, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24657857, Length=203, Percent_Identity=30.0492610837438, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI281365664, Length=203, Percent_Identity=30.0492610837438, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI281361635, Length=132, Percent_Identity=28.030303030303, Blast_Score=71, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR018080
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: NA

Molecular weight: Translated: 31060; Mature: 30929

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVGTIIVLAFLAFVAVTIFKGVRIVPQGYKWIVQRLGKYHSTLNPGLNFVIPYIDDVAY
CCHHHHHHHHHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHCCCCCCEEEHHHCCCEE
KVTTKDIVLDIPSQEVITRDNAVLLMNAVAYINLTTPEKAVYGIENYTWAIQNLVQTSLR
EEEECEEEEECCCHHHHCCCCEEEEEEEEEEEEECCCHHHHHCCCHHHHHHHHHHHHHHH
SIVGEMDLDDALSSRDHIKAKLKAAISDDISDWGITLKTVEIQDIQPSSTMQAAMEAQAA
HHHCCCCHHHHHCCHHHHHHHHHHHHHCCCHHCCEEEEEEEEECCCCHHHHHHHHHHHHH
AERQRRATVTKADGEKQAAILEADGRLEASRRDAEAQVVLAEASQKAIEMVTSAVGDKEI
HHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHCCCCCC
PVAYLLGEQYVKAMQEMAKSSNAKTVVLPADVLNTIRGIMGKHN
CHHHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PVGTIIVLAFLAFVAVTIFKGVRIVPQGYKWIVQRLGKYHSTLNPGLNFVIPYIDDVAY
CHHHHHHHHHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHCCCCCCEEEHHHCCCEE
KVTTKDIVLDIPSQEVITRDNAVLLMNAVAYINLTTPEKAVYGIENYTWAIQNLVQTSLR
EEEECEEEEECCCHHHHCCCCEEEEEEEEEEEEECCCHHHHHCCCHHHHHHHHHHHHHHH
SIVGEMDLDDALSSRDHIKAKLKAAISDDISDWGITLKTVEIQDIQPSSTMQAAMEAQAA
HHHCCCCHHHHHCCHHHHHHHHHHHHHCCCHHCCEEEEEEEEECCCCHHHHHHHHHHHHH
AERQRRATVTKADGEKQAAILEADGRLEASRRDAEAQVVLAEASQKAIEMVTSAVGDKEI
HHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHCCCCCC
PVAYLLGEQYVKAMQEMAKSSNAKTVVLPADVLNTIRGIMGKHN
CHHHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]