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The map label for this gene is trpS [H]

Identifier: 213157641

GI number: 213157641

Start: 3241092

End: 3242105

Strand: Direct

Name: trpS [H]

Synonym: AB57_3118

Alternate gene names: 213157641

Gene position: 3241092-3242105 (Clockwise)

Preceding gene: 213157631

Following gene: 213157644

Centisome position: 80.02

GC content: 39.94

Gene sequence:

>1014_bases
ATGAGTAATGTTGATCAGCGTCCAATTATTTTGACAGGCGACCGCCCAACCGGACAACTTCACCTCGGGCATTTTGTCGG
TTCTTTGCGTTCTCGTGTAGGTCTACAGGATAGCCATCATCAACATCTCTTATTAGCAGATGCACAAGCGTTAACAGACA
ATGCCGATAACCCAGATAAAGTGCGCCGTAACATTTTAGAAGTTGCTCTAGACTATTTAGCGGTAGGCATTGATCCAACT
AAAACCACAATTTGTGTACAGTCATGCTTGCCTGCACTGAATGAGCTTACAATGTTATATCTTAACTTTGTAACTGTAGC
TCGATTGGAACGTAACCCAACCATCAAATCTGAAATTCAAATGCGTGGTTTTGAACGTGATATTCCTGCCGGTTTCCTTT
GCTACCCTGTAGCACAGGCAGCTGATATTACGGCTTTTAAAGCGACTGTAGTACCAGTAGGTGAAGATCAAATTCCAATG
ATTGAGCAAACTAACGAAATCGTGCGTCGTGTAAACCGACAAATTGGTCAAGACCTTTTACCTGAATGTAAAGCTTTGCT
TTCTAATATGGCTCGTTTACCTGGTTTTGATGGTAAAGCGAAAATGTCTAAGTCATTAGGCAATACCATTGTTTTAAATG
CTTCTGACAAAGACATCAAAAAAGCTGTAAATGCGATGTATACCGATCCAAATCATCTTCGCATCGAAGATCCGGGCCAA
GTTGAAGGAAACATTGTATTTACTTATTTAGATGCATTTGATCCAAATAAAGAAGAAGTTGAAGAGCTAAAAGCACACTA
CCGCCGTGGTGGTCTTGGTGATGGTACAGTTAAAAAACGTCTTGAAGGTGTACTAAAAGAATTAATTACACCTATACGTG
AACGTCGTGAAGAACTTGCTAAAGATCCTGACTATATTATGGATGTTTTACGCCAAGGTACTGATAAATGTCGAATCATT
ACCCAGCAGACTTTGGACGAAGTTAAAGATGGTTTAGGCTTATTTAAGTTCTAA

Upstream 100 bases:

>100_bases
TTGCTGACGAAAAAATTTTATTTCCCGTACAATAATGCCAATCTTTTATATTGCAGGGCTTATTATCCCTGATTAAGCCA
ATACCATAGTGGAATAAATA

Downstream 100 bases:

>100_bases
TTTTTATATTAGAGATATAAATCAAAAAAGCCCTACGGGGCTTTTTTTATAATTATTTTTAGATTCAACAATTTAATTTT
TTAGAATTTCTATATATTTA

Product: tryptophanyl-tRNA synthetase II

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MSNVDQRPIILTGDRPTGQLHLGHFVGSLRSRVGLQDSHHQHLLLADAQALTDNADNPDKVRRNILEVALDYLAVGIDPT
KTTICVQSCLPALNELTMLYLNFVTVARLERNPTIKSEIQMRGFERDIPAGFLCYPVAQAADITAFKATVVPVGEDQIPM
IEQTNEIVRRVNRQIGQDLLPECKALLSNMARLPGFDGKAKMSKSLGNTIVLNASDKDIKKAVNAMYTDPNHLRIEDPGQ
VEGNIVFTYLDAFDPNKEEVEELKAHYRRGGLGDGTVKKRLEGVLKELITPIRERREELAKDPDYIMDVLRQGTDKCRII
TQQTLDEVKDGLGLFKF

Sequences:

>Translated_337_residues
MSNVDQRPIILTGDRPTGQLHLGHFVGSLRSRVGLQDSHHQHLLLADAQALTDNADNPDKVRRNILEVALDYLAVGIDPT
KTTICVQSCLPALNELTMLYLNFVTVARLERNPTIKSEIQMRGFERDIPAGFLCYPVAQAADITAFKATVVPVGEDQIPM
IEQTNEIVRRVNRQIGQDLLPECKALLSNMARLPGFDGKAKMSKSLGNTIVLNASDKDIKKAVNAMYTDPNHLRIEDPGQ
VEGNIVFTYLDAFDPNKEEVEELKAHYRRGGLGDGTVKKRLEGVLKELITPIRERREELAKDPDYIMDVLRQGTDKCRII
TQQTLDEVKDGLGLFKF
>Mature_336_residues
SNVDQRPIILTGDRPTGQLHLGHFVGSLRSRVGLQDSHHQHLLLADAQALTDNADNPDKVRRNILEVALDYLAVGIDPTK
TTICVQSCLPALNELTMLYLNFVTVARLERNPTIKSEIQMRGFERDIPAGFLCYPVAQAADITAFKATVVPVGEDQIPMI
EQTNEIVRRVNRQIGQDLLPECKALLSNMARLPGFDGKAKMSKSLGNTIVLNASDKDIKKAVNAMYTDPNHLRIEDPGQV
EGNIVFTYLDAFDPNKEEVEELKAHYRRGGLGDGTVKKRLEGVLKELITPIRERREELAKDPDYIMDVLRQGTDKCRIIT
QQTLDEVKDGLGLFKF

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=338, Percent_Identity=29.8816568047337, Blast_Score=129, Evalue=3e-30,
Organism=Homo sapiens, GI41352700, Length=185, Percent_Identity=33.5135135135135, Blast_Score=99, Evalue=7e-21,
Organism=Escherichia coli, GI1789786, Length=335, Percent_Identity=28.6567164179104, Blast_Score=127, Evalue=7e-31,
Organism=Caenorhabditis elegans, GI71982800, Length=353, Percent_Identity=27.7620396600567, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI71982793, Length=353, Percent_Identity=27.7620396600567, Blast_Score=118, Evalue=4e-27,
Organism=Saccharomyces cerevisiae, GI6320474, Length=344, Percent_Identity=27.0348837209302, Blast_Score=100, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24666151, Length=338, Percent_Identity=31.9526627218935, Blast_Score=137, Evalue=8e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 37668; Mature: 37537

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNVDQRPIILTGDRPTGQLHLGHFVGSLRSRVGLQDSHHQHLLLADAQALTDNADNPDK
CCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEECHHHHHCCCCCHHH
VRRNILEVALDYLAVGIDPTKTTICVQSCLPALNELTMLYLNFVTVARLERNPTIKSEIQ
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
MRGFERDIPAGFLCYPVAQAADITAFKATVVPVGEDQIPMIEQTNEIVRRVNRQIGQDLL
HCCCCCCCCCCHHHHHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
PECKALLSNMARLPGFDGKAKMSKSLGNTIVLNASDKDIKKAVNAMYTDPNHLRIEDPGQ
HHHHHHHHHHHHCCCCCCHHHHHHHCCCEEEEECCCHHHHHHHHHHCCCCCEEEECCCCC
VEGNIVFTYLDAFDPNKEEVEELKAHYRRGGLGDGTVKKRLEGVLKELITPIRERREELA
CCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KDPDYIMDVLRQGTDKCRIITQQTLDEVKDGLGLFKF
CCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SNVDQRPIILTGDRPTGQLHLGHFVGSLRSRVGLQDSHHQHLLLADAQALTDNADNPDK
CCCCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEECHHHHHCCCCCHHH
VRRNILEVALDYLAVGIDPTKTTICVQSCLPALNELTMLYLNFVTVARLERNPTIKSEIQ
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
MRGFERDIPAGFLCYPVAQAADITAFKATVVPVGEDQIPMIEQTNEIVRRVNRQIGQDLL
HCCCCCCCCCCHHHHHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
PECKALLSNMARLPGFDGKAKMSKSLGNTIVLNASDKDIKKAVNAMYTDPNHLRIEDPGQ
HHHHHHHHHHHHCCCCCCHHHHHHHCCCEEEEECCCHHHHHHHHHHCCCCCEEEECCCCC
VEGNIVFTYLDAFDPNKEEVEELKAHYRRGGLGDGTVKKRLEGVLKELITPIRERREELA
CCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KDPDYIMDVLRQGTDKCRIITQQTLDEVKDGLGLFKF
CCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA