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The map label for this gene is catB2 [H]

Identifier: 213157627

GI number: 213157627

Start: 3213592

End: 3214311

Strand: Direct

Name: catB2 [H]

Synonym: AB57_3104

Alternate gene names: 213157627

Gene position: 3213592-3214311 (Clockwise)

Preceding gene: 213157626

Following gene: 213157628

Centisome position: 79.34

GC content: 36.94

Gene sequence:

>720_bases
ATGGATACTCCTCTAATTAACACACCAGTCCGCCATTGGTGTGAATTTGAGTTTATTTCCAAAACTGTGAAAAATCCAAA
TATCCATATTAAAGGGAATTACTCTTACTACTCGGCATATTGGGATCAAGGTTTTGAACGCTGTGTAGTGCGATATCTAC
ATGACAAGCCTTCTACTCCAGACAAGCCAATTGATCAGCTCTATATTGGTAATTTTGTTTGTTTTGGCGCTGAATGCGTG
ATTATGATGGGTGGTAACCAACTTCATCGGCCAGACTGGATATCGACATTCCCCTTTGACACCCGAAGTTTTTTAGCCGC
TGGTGACACTATAATTGCAGATGGCTGCTGGATTGGAAGTCGTGCAATGATTATGCAAGGTGTAAAAATCGGTGAAGGTG
CTGTTGTTGCAACTGGAGCTGTGGTCACTAAAGATGTCCCTCCTTATACAATTGTTGGTGGCGTACCTGCAAAAATTATT
AAATACCGTTTTCCTCAGGAGCAAATAGAAAAACTACTTGCTTTAAAAATTTATGATTTAGATGAAAAACAAGTTTTAAA
AATGCGGGAATATTTACAAACGGATGATATAGATGCATTAACAGCACATCTTAAAAAATTAACAGAGCGAATAAAATATA
TTTGCAAGATTTCTTGCTTAAAAACACAAATGATTACGTGCTCGAATTTCAATCGTAAGAAAAGAAGTATAAAGTATTGA

Upstream 100 bases:

>100_bases
TGTAAGTGTAGAATACCTCTAAGGTAATACACTTGAACCCCTCTTTATGAGGGGTTTTTATTTAATATGGTTTGGCTCAT
TTTTGTTTGGATAATAAATT

Downstream 100 bases:

>100_bases
ATAAATAACCATCATTACAATAAGGAATAAACTCATGTTATATCAACATATTCTTGTACCAATTGACGGTTCTGAAACTT
CTATGGTTGCTATGAAAGAA

Product: chloramphenicol acetyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MDTPLINTPVRHWCEFEFISKTVKNPNIHIKGNYSYYSAYWDQGFERCVVRYLHDKPSTPDKPIDQLYIGNFVCFGAECV
IMMGGNQLHRPDWISTFPFDTRSFLAAGDTIIADGCWIGSRAMIMQGVKIGEGAVVATGAVVTKDVPPYTIVGGVPAKII
KYRFPQEQIEKLLALKIYDLDEKQVLKMREYLQTDDIDALTAHLKKLTERIKYICKISCLKTQMITCSNFNRKKRSIKY

Sequences:

>Translated_239_residues
MDTPLINTPVRHWCEFEFISKTVKNPNIHIKGNYSYYSAYWDQGFERCVVRYLHDKPSTPDKPIDQLYIGNFVCFGAECV
IMMGGNQLHRPDWISTFPFDTRSFLAAGDTIIADGCWIGSRAMIMQGVKIGEGAVVATGAVVTKDVPPYTIVGGVPAKII
KYRFPQEQIEKLLALKIYDLDEKQVLKMREYLQTDDIDALTAHLKKLTERIKYICKISCLKTQMITCSNFNRKKRSIKY
>Mature_239_residues
MDTPLINTPVRHWCEFEFISKTVKNPNIHIKGNYSYYSAYWDQGFERCVVRYLHDKPSTPDKPIDQLYIGNFVCFGAECV
IMMGGNQLHRPDWISTFPFDTRSFLAAGDTIIADGCWIGSRAMIMQGVKIGEGAVVATGAVVTKDVPPYTIVGGVPAKII
KYRFPQEQIEKLLALKIYDLDEKQVLKMREYLQTDDIDALTAHLKKLTERIKYICKISCLKTQMITCSNFNRKKRSIKY

Specific function: This enzyme is an effector of chloramphenicol resistance in bacteria [H]

COG id: COG0110

COG function: function code R; Acetyltransferase (isoleucine patch superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1786664, Length=102, Percent_Identity=41.1764705882353, Blast_Score=69, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001451
- InterPro:   IPR018357
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00132 Hexapep [H]

EC number: =2.3.1.28 [H]

Molecular weight: Translated: 27348; Mature: 27348

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTPLINTPVRHWCEFEFISKTVKNPNIHIKGNYSYYSAYWDQGFERCVVRYLHDKPSTP
CCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCEEHHHHHHHHHHHHHHHHHCCCCCC
DKPIDQLYIGNFVCFGAECVIMMGGNQLHRPDWISTFPFDTRSFLAAGDTIIADGCWIGS
CCCHHHHHHCCEEEECCEEEEEECCCCCCCCCCCCCCCCCCHHHHHCCCEEEECCCEECC
RAMIMQGVKIGEGAVVATGAVVTKDVPPYTIVGGVPAKIIKYRFPQEQIEKLLALKIYDL
HHHHHCCCEECCCEEEEECEEEECCCCCEEEECCCHHHHHHCCCCHHHHHHHHHHHEECC
DEKQVLKMREYLQTDDIDALTAHLKKLTERIKYICKISCLKTQMITCSNFNRKKRSIKY
CHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHCCCC
>Mature Secondary Structure
MDTPLINTPVRHWCEFEFISKTVKNPNIHIKGNYSYYSAYWDQGFERCVVRYLHDKPSTP
CCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCEEHHHHHHHHHHHHHHHHHCCCCCC
DKPIDQLYIGNFVCFGAECVIMMGGNQLHRPDWISTFPFDTRSFLAAGDTIIADGCWIGS
CCCHHHHHHCCEEEECCEEEEEECCCCCCCCCCCCCCCCCCHHHHHCCCEEEECCCEECC
RAMIMQGVKIGEGAVVATGAVVTKDVPPYTIVGGVPAKIIKYRFPQEQIEKLLALKIYDL
HHHHHCCCEECCCEEEEECEEEECCCCCEEEECCCHHHHHHCCCCHHHHHHHHHHHEECC
DEKQVLKMREYLQTDDIDALTAHLKKLTERIKYICKISCLKTQMITCSNFNRKKRSIKY
CHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1314803 [H]