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The map label for this gene is carA [H]

Identifier: 213157624

GI number: 213157624

Start: 3208565

End: 3209704

Strand: Direct

Name: carA [H]

Synonym: AB57_3101

Alternate gene names: 213157624

Gene position: 3208565-3209704 (Clockwise)

Preceding gene: 213157622

Following gene: 213157625

Centisome position: 79.21

GC content: 42.63

Gene sequence:

>1140_bases
TTGAGCACCCCCGCCATTTTAGCCCTCGCAGATGGAACGATCTTTAAAGGAACGTCAATCGGCGCAACGGGAAGTACGAC
TGGAGAAGTCGTTTTTAACACAGCCATGACAGGCTATCAAGAAATTTTGACTGACCCAAGTTATGCACAACAAATTGTGA
CATTAACTTACCCTCATATTGGTAACACTGGTTGCAACGAAGAAGACGTTGAATCTGGTCGTATCCATAAAGTATGGGCG
AATGGTTTAATTATTCGTGACCTTCCACTATTACACAGCAACTTCCGTTCTGAGCAATCATTAAGTGAATATTTGCAAGC
GCACAATGTTGTCGCAATTGCTGATATTGACACACGTAAACTTACTCGTATTTTACGTGATAAAGGTGCACAAAATGGTT
GCATCCTTGCTGGCGAAAATATTACTGAAGAAGAAGCTATTGCTAAAGCTCGCGCTTTTGGTGGTTTAAATGGTTTAGAC
CTTGCAAAAGAGTGCTGTGACCCGACAGGCTTTGAATGGTCTGAAGGTTCGTGGGTATTAGGTAAAGGCTTTACTCAACC
TGAGTTAAAATACCATGTGGTTGCATACGATTATGGTGTCAAAACCAACATCTTGCGTATGCTTGCAGACCGCGGTTGTA
AACTCACTGTTGTCCCTGCTGAAACTCCGGCTGAAAAAGTATTAGCACTTAATCCGGATGGCGTATTCCTTTCAAACGGC
CCTGGCGACCCAGCTGCTTGTGATTACGCTATCGAAGCTGTAAAAACTATTGTTGAAACCACAACATTACCTGTATTTGG
TATCTGTTTAGGACACCAAATCTTGGCACTCGCTTCTGGTGCAAAAACTGTAAAAATGAATCATGGTCACCACGGTGCGA
ACCACCCTGTACAAAATCTTGAAGATGGTACAGTGATGATTACATCTCAAAACCATGGTTTTGCTGTAGATGCAGAAACA
TTACCGGCTAACTTAAAAGCAACGCATAAATCATTGTTCGATGGCACTCTACAAGGGATTCATCGTATAGACAAACCAGC
TTTCAGCTTCCAAGGTCACCCTGAAGCAAGCCCAGGTCCACATGATTGTGCACCTTTGTTCGATCATTTCATCGAACTTA
TTGAAGCATCTAAACAGTAA

Upstream 100 bases:

>100_bases
AAGCGAGCAGACCAGTGAGGAGGGGCATGTTTTTTTAGAACATCGCCTATCTTTTTTAGGTCTACTCGCTTTTTTACAGC
CGAAATTCAGGAGCTTTGGT

Downstream 100 bases:

>100_bases
TTAAGGAGCGAATAATGCCTAAACGTACGGATATTAAAAGCATCTTAATTATTGGTGCTGGTCCAATTGTCATTGGTCAA
GCTTGTGAGTTTGACTATTC

Product: carbamoyl phosphate synthase small subunit

Products: NA

Alternate protein names: Carbamoyl-phosphate synthetase glutamine chain [H]

Number of amino acids: Translated: 379; Mature: 378

Protein sequence:

>379_residues
MSTPAILALADGTIFKGTSIGATGSTTGEVVFNTAMTGYQEILTDPSYAQQIVTLTYPHIGNTGCNEEDVESGRIHKVWA
NGLIIRDLPLLHSNFRSEQSLSEYLQAHNVVAIADIDTRKLTRILRDKGAQNGCILAGENITEEEAIAKARAFGGLNGLD
LAKECCDPTGFEWSEGSWVLGKGFTQPELKYHVVAYDYGVKTNILRMLADRGCKLTVVPAETPAEKVLALNPDGVFLSNG
PGDPAACDYAIEAVKTIVETTTLPVFGICLGHQILALASGAKTVKMNHGHHGANHPVQNLEDGTVMITSQNHGFAVDAET
LPANLKATHKSLFDGTLQGIHRIDKPAFSFQGHPEASPGPHDCAPLFDHFIELIEASKQ

Sequences:

>Translated_379_residues
MSTPAILALADGTIFKGTSIGATGSTTGEVVFNTAMTGYQEILTDPSYAQQIVTLTYPHIGNTGCNEEDVESGRIHKVWA
NGLIIRDLPLLHSNFRSEQSLSEYLQAHNVVAIADIDTRKLTRILRDKGAQNGCILAGENITEEEAIAKARAFGGLNGLD
LAKECCDPTGFEWSEGSWVLGKGFTQPELKYHVVAYDYGVKTNILRMLADRGCKLTVVPAETPAEKVLALNPDGVFLSNG
PGDPAACDYAIEAVKTIVETTTLPVFGICLGHQILALASGAKTVKMNHGHHGANHPVQNLEDGTVMITSQNHGFAVDAET
LPANLKATHKSLFDGTLQGIHRIDKPAFSFQGHPEASPGPHDCAPLFDHFIELIEASKQ
>Mature_378_residues
STPAILALADGTIFKGTSIGATGSTTGEVVFNTAMTGYQEILTDPSYAQQIVTLTYPHIGNTGCNEEDVESGRIHKVWAN
GLIIRDLPLLHSNFRSEQSLSEYLQAHNVVAIADIDTRKLTRILRDKGAQNGCILAGENITEEEAIAKARAFGGLNGLDL
AKECCDPTGFEWSEGSWVLGKGFTQPELKYHVVAYDYGVKTNILRMLADRGCKLTVVPAETPAEKVLALNPDGVFLSNGP
GDPAACDYAIEAVKTIVETTTLPVFGICLGHQILALASGAKTVKMNHGHHGANHPVQNLEDGTVMITSQNHGFAVDAETL
PANLKATHKSLFDGTLQGIHRIDKPAFSFQGHPEASPGPHDCAPLFDHFIELIEASKQ

Specific function: Arginine biosynthesis. Pyrimidine biosynthesis; first step. [C]

COG id: COG0505

COG function: function code EF; Carbamoylphosphate synthase small subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI18105007, Length=381, Percent_Identity=38.3202099737533, Blast_Score=234, Evalue=1e-61,
Organism=Homo sapiens, GI21361331, Length=380, Percent_Identity=38.1578947368421, Blast_Score=220, Evalue=2e-57,
Organism=Homo sapiens, GI169790915, Length=380, Percent_Identity=38.1578947368421, Blast_Score=220, Evalue=2e-57,
Organism=Escherichia coli, GI1786215, Length=383, Percent_Identity=69.4516971279373, Blast_Score=559, Evalue=1e-160,
Organism=Caenorhabditis elegans, GI193204318, Length=386, Percent_Identity=39.119170984456, Blast_Score=248, Evalue=4e-66,
Organism=Saccharomyces cerevisiae, GI6322331, Length=398, Percent_Identity=37.6884422110553, Blast_Score=233, Evalue=3e-62,
Organism=Saccharomyces cerevisiae, GI6324878, Length=388, Percent_Identity=37.8865979381443, Blast_Score=228, Evalue=1e-60,
Organism=Drosophila melanogaster, GI45555749, Length=389, Percent_Identity=39.5886889460154, Blast_Score=238, Evalue=4e-63,
Organism=Drosophila melanogaster, GI24642586, Length=389, Percent_Identity=39.5886889460154, Blast_Score=238, Evalue=5e-63,

Paralogues:

None

Copy number: 620 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2599 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR006274
- InterPro:   IPR002474
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991 [H]

Pfam domain/function: PF00988 CPSase_sm_chain; PF00117 GATase [H]

EC number: =6.3.5.5 [H]

Molecular weight: Translated: 40664; Mature: 40533

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTPAILALADGTIFKGTSIGATGSTTGEVVFNTAMTGYQEILTDPSYAQQIVTLTYPHI
CCCCEEEEEECCCEEECCCCCCCCCCCCCEEEEHHHHHHHHHHCCHHHHHEEEEEECCCC
GNTGCNEEDVESGRIHKVWANGLIIRDLPLLHSNFRSEQSLSEYLQAHNVVAIADIDTRK
CCCCCCHHHCCCCCEEEEECCCEEEECCHHHHHHCCCHHHHHHHHHHCCEEEEEECCHHH
LTRILRDKGAQNGCILAGENITEEEAIAKARAFGGLNGLDLAKECCDPTGFEWSEGSWVL
HHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCEEE
GKGFTQPELKYHVVAYDYGVKTNILRMLADRGCKLTVVPAETPAEKVLALNPDGVFLSNG
ECCCCCCCCEEEEEEEECCCHHHHHHHHHCCCCEEEEEECCCCCCCEEEECCCCEEEECC
PGDPAACDYAIEAVKTIVETTTLPVFGICLGHQILALASGAKTVKMNHGHHGANHPVQNL
CCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCC
EDGTVMITSQNHGFAVDAETLPANLKATHKSLFDGTLQGIHRIDKPAFSFQGHPEASPGP
CCCEEEEEECCCCEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
HDCAPLFDHFIELIEASKQ
CCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
STPAILALADGTIFKGTSIGATGSTTGEVVFNTAMTGYQEILTDPSYAQQIVTLTYPHI
CCCEEEEEECCCEEECCCCCCCCCCCCCEEEEHHHHHHHHHHCCHHHHHEEEEEECCCC
GNTGCNEEDVESGRIHKVWANGLIIRDLPLLHSNFRSEQSLSEYLQAHNVVAIADIDTRK
CCCCCCHHHCCCCCEEEEECCCEEEECCHHHHHHCCCHHHHHHHHHHCCEEEEEECCHHH
LTRILRDKGAQNGCILAGENITEEEAIAKARAFGGLNGLDLAKECCDPTGFEWSEGSWVL
HHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCEEE
GKGFTQPELKYHVVAYDYGVKTNILRMLADRGCKLTVVPAETPAEKVLALNPDGVFLSNG
ECCCCCCCCEEEEEEEECCCHHHHHHHHHCCCCEEEEEECCCCCCCEEEECCCCEEEECC
PGDPAACDYAIEAVKTIVETTTLPVFGICLGHQILALASGAKTVKMNHGHHGANHPVQNL
CCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCC
EDGTVMITSQNHGFAVDAETLPANLKATHKSLFDGTLQGIHRIDKPAFSFQGHPEASPGP
CCCEEEEEECCCCEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
HDCAPLFDHFIELIEASKQ
CCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA