Click here to switch to the map view.

The map label for this gene is 213157603

Identifier: 213157603

GI number: 213157603

Start: 2381629

End: 2382807

Strand: Reverse

Name: 213157603

Synonym: AB57_2296

Alternate gene names: NA

Gene position: 2382807-2381629 (Counterclockwise)

Preceding gene: 213157604

Following gene: 213157600

Centisome position: 58.83

GC content: 38.42

Gene sequence:

>1179_bases
ATGAATATTCGCCAAGTGTCTGCTATTTGTCTTTCAATAGCAGCTACTCATTTTGTGTATGCCGCTTCAAATGTTGTAAA
TCCTGTAAATGATTCTTCCCAAGCAAAAGGAATTATTAAAAATCAATATATTGTTATATTAAATAAGGATGCAGGTCCTT
CTAAAGATTTCGCACAAAATATTGCTAAACAACATGCTGGTAAAGTTTTACAAAGCTACGATACTGTTCTTAAAGGTTTT
GCAATTTATTTACCTGATACAGCAGGGACAGCCTTTATTGAAGCGATGAAAAAGAACCCTCAAGTTCTTTCAGTAGAAAG
CGATACAATAGTAAATATTGATGCAACTACTCAAAGTAATCCAGATTGGGGACTAGATCGTATAGACCAGAAAGCTTTAC
CATTAAATTCGGCTTATTCTTATTTACAGACCGGTTCAGGTACTACGGCTTATATCGTGGATACTGGTATATTATCTAGT
CACCAAGAGTTTTCAGGACGTGTGTTAAGCGGTTATACCGCAATATCTGATGGCAATGGTACAACCGACTGTAATGGACA
CGGGACCCATGTTGCTGGAACCGTAGGTGGTACGACCTATGGTGTTGCCAAAAATGTCAATTTAGTTCCTATCCGGATTT
TGGGGTGTGATGGGTCAGGGGCCTCAAGTAATGTTATTGCTGGTTTAGACTGGATATTAAAAAATGGTAAAAAACCTGCA
GTTGTAAATATGTCTTTAGGTGGGGCAACAAGTTCTTCTTTAGATAGTGCAGTGGAAAACTTATTTAATAATGGTTATGT
CATGGTCGTAGCCGCTGGCAATTCTAATACAGATGCATGTAGTTCTTCTCCTGCCAGAGTAAGTAAGGCGATTACTGTTG
CTGCTACAGATAATACAGATACTCGAGCCAGCTATTCTAATTATGGAAGCTGTGTTGATATTTTTGCACCTGGAAGTCAG
ATTAACTCTTCTTGGATTGGAAGTAATACAGCTACCAAGATATTAAATGGTACTTCAATGGCAACCCCGCATGTTGCTGG
TGTAGTTGCTGAAATGCTTCAAAGTACACCTACGGCTTCACCTCAAACGATCTCTACCAATCTTTTAAATCAAGCGAGCA
GTAACGTAGTAAAAAACCCTTCATGTAGCCCAAACCGCTTGTTATATAAATCTCCTTAA

Upstream 100 bases:

>100_bases
AGATAAAACTCCTCAAAGTTCTCATCTAAAATTTTAATCCTGAAGTAAAAAGTTATTAATTATCATAAAAATACCTGAAA
TATAATATATGGAGATAGTC

Downstream 100 bases:

>100_bases
TAAAAATATAATTCTCTATGATTGAAAAGGTCCCGAAGGACCTTTTTTTAAATTTTTGCATGTGTACCATACTTGTCAAT
CATGATTGAACTGGCTTCAT

Product: extracellular serine protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MNIRQVSAICLSIAATHFVYAASNVVNPVNDSSQAKGIIKNQYIVILNKDAGPSKDFAQNIAKQHAGKVLQSYDTVLKGF
AIYLPDTAGTAFIEAMKKNPQVLSVESDTIVNIDATTQSNPDWGLDRIDQKALPLNSAYSYLQTGSGTTAYIVDTGILSS
HQEFSGRVLSGYTAISDGNGTTDCNGHGTHVAGTVGGTTYGVAKNVNLVPIRILGCDGSGASSNVIAGLDWILKNGKKPA
VVNMSLGGATSSSLDSAVENLFNNGYVMVVAAGNSNTDACSSSPARVSKAITVAATDNTDTRASYSNYGSCVDIFAPGSQ
INSSWIGSNTATKILNGTSMATPHVAGVVAEMLQSTPTASPQTISTNLLNQASSNVVKNPSCSPNRLLYKSP

Sequences:

>Translated_392_residues
MNIRQVSAICLSIAATHFVYAASNVVNPVNDSSQAKGIIKNQYIVILNKDAGPSKDFAQNIAKQHAGKVLQSYDTVLKGF
AIYLPDTAGTAFIEAMKKNPQVLSVESDTIVNIDATTQSNPDWGLDRIDQKALPLNSAYSYLQTGSGTTAYIVDTGILSS
HQEFSGRVLSGYTAISDGNGTTDCNGHGTHVAGTVGGTTYGVAKNVNLVPIRILGCDGSGASSNVIAGLDWILKNGKKPA
VVNMSLGGATSSSLDSAVENLFNNGYVMVVAAGNSNTDACSSSPARVSKAITVAATDNTDTRASYSNYGSCVDIFAPGSQ
INSSWIGSNTATKILNGTSMATPHVAGVVAEMLQSTPTASPQTISTNLLNQASSNVVKNPSCSPNRLLYKSP
>Mature_392_residues
MNIRQVSAICLSIAATHFVYAASNVVNPVNDSSQAKGIIKNQYIVILNKDAGPSKDFAQNIAKQHAGKVLQSYDTVLKGF
AIYLPDTAGTAFIEAMKKNPQVLSVESDTIVNIDATTQSNPDWGLDRIDQKALPLNSAYSYLQTGSGTTAYIVDTGILSS
HQEFSGRVLSGYTAISDGNGTTDCNGHGTHVAGTVGGTTYGVAKNVNLVPIRILGCDGSGASSNVIAGLDWILKNGKKPA
VVNMSLGGATSSSLDSAVENLFNNGYVMVVAAGNSNTDACSSSPARVSKAITVAATDNTDTRASYSNYGSCVDIFAPGSQ
INSSWIGSNTATKILNGTSMATPHVAGVVAEMLQSTPTASPQTISTNLLNQASSNVVKNPSCSPNRLLYKSP

Specific function: Serine proteinase with preferred activity for amino acids with aromatic side groups at the P1' side of the scissible bond [H]

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

Organism=Homo sapiens, GI31317307, Length=357, Percent_Identity=32.4929971988796, Blast_Score=152, Evalue=7e-37,
Organism=Saccharomyces cerevisiae, GI6320775, Length=410, Percent_Identity=35.8536585365854, Blast_Score=228, Evalue=2e-60,
Organism=Saccharomyces cerevisiae, GI6324576, Length=339, Percent_Identity=36.283185840708, Blast_Score=213, Evalue=5e-56,
Organism=Saccharomyces cerevisiae, GI6319893, Length=269, Percent_Identity=43.8661710037175, Blast_Score=195, Evalue=9e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500
- InterPro:   IPR009020
- InterPro:   IPR010259 [H]

Pfam domain/function: PF05922 Inhibitor_I9; PF00082 Peptidase_S8 [H]

EC number: NA

Molecular weight: Translated: 40714; Mature: 40714

Theoretical pI: Translated: 7.46; Mature: 7.46

Prosite motif: PS00136 SUBTILASE_ASP ; PS00137 SUBTILASE_HIS ; PS00138 SUBTILASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIRQVSAICLSIAATHFVYAASNVVNPVNDSSQAKGIIKNQYIVILNKDAGPSKDFAQN
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCEECCCEEEEEECCCCCCHHHHHH
IAKQHAGKVLQSYDTVLKGFAIYLPDTAGTAFIEAMKKNPQVLSVESDTIVNIDATTQSN
HHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHCCCCEEEECCCEEEEEECCCCCC
PDWGLDRIDQKALPLNSAYSYLQTGSGTTAYIVDTGILSSHQEFSGRVLSGYTAISDGNG
CCCCHHHHCHHCCCCHHHHHHHHCCCCCEEEEEECCCCCCCHHHCCEEEECEEEEECCCC
TTDCNGHGTHVAGTVGGTTYGVAKNVNLVPIRILGCDGSGASSNVIAGLDWILKNGKKPA
CCCCCCCCCEEEEECCCCEEHHCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHCCCCCE
VVNMSLGGATSSSLDSAVENLFNNGYVMVVAAGNSNTDACSSSPARVSKAITVAATDNTD
EEEEECCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCHHEEEEEEEECCCCC
TRASYSNYGSCVDIFAPGSQINSSWIGSNTATKILNGTSMATPHVAGVVAEMLQSTPTAS
CCCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHEECCCCCCCCHHHHHHHHHHHCCCCCC
PQTISTNLLNQASSNVVKNPSCSPNRLLYKSP
CCHHHHHHHHHHHCCCCCCCCCCCCEEEECCC
>Mature Secondary Structure
MNIRQVSAICLSIAATHFVYAASNVVNPVNDSSQAKGIIKNQYIVILNKDAGPSKDFAQN
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCEECCCEEEEEECCCCCCHHHHHH
IAKQHAGKVLQSYDTVLKGFAIYLPDTAGTAFIEAMKKNPQVLSVESDTIVNIDATTQSN
HHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHCCCCEEEECCCEEEEEECCCCCC
PDWGLDRIDQKALPLNSAYSYLQTGSGTTAYIVDTGILSSHQEFSGRVLSGYTAISDGNG
CCCCHHHHCHHCCCCHHHHHHHHCCCCCEEEEEECCCCCCCHHHCCEEEECEEEEECCCC
TTDCNGHGTHVAGTVGGTTYGVAKNVNLVPIRILGCDGSGASSNVIAGLDWILKNGKKPA
CCCCCCCCCEEEEECCCCEEHHCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHCCCCCE
VVNMSLGGATSSSLDSAVENLFNNGYVMVVAAGNSNTDACSSSPARVSKAITVAATDNTD
EEEEECCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCHHEEEEEEEECCCCC
TRASYSNYGSCVDIFAPGSQINSSWIGSNTATKILNGTSMATPHVAGVVAEMLQSTPTAS
CCCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHEECCCCCCCCHHHHHHHHHHHCCCCCC
PQTISTNLLNQASSNVVKNPSCSPNRLLYKSP
CCHHHHHHHHHHHCCCCCCCCCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7551039; 1499549 [H]