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The map label for this gene is argD [H]

Identifier: 213157581

GI number: 213157581

Start: 2357926

End: 2359134

Strand: Reverse

Name: argD [H]

Synonym: AB57_2274

Alternate gene names: 213157581

Gene position: 2359134-2357926 (Counterclockwise)

Preceding gene: 213157583

Following gene: 213157577

Centisome position: 58.24

GC content: 41.36

Gene sequence:

>1209_bases
ATGACTGATATTACCCTAGCTCCAGTACAACCTGATCAACCAACACATTTAATGGCTACTTATGGTCGCCAAGCGATCAG
TTTTGTTCGAGGCCGAGGGGCGTATCTTTATACAAAAGATGGTACAGAATATTTAGATGCACTCACTGGTATTGCTGTAT
GTGGTTTAGGGCACGCTCATCCAGCTATTGCAGAAGCCATTGCAGAGCAAGCTGCTACACTTGTGCATACGAGTAATTTG
TTTGAAATTCCTTGGCAAACTGCGGCTGCTCAAAAGCTTGCTGAAGTTTCAGGTATGGAGGAAATTTTCTTTTCAAACAG
CGGTGCCGAGTCAAATGAAGGAGCAATTAAAATTGCTCGTAAATTTGGTACTCAACAAGGTATAAGCTTGCCAAAGATTA
TCGTTGCTGAGCAGTCATTTCATGGTCGTACTTTGGCGACACTGTCAGCAACTGGTAACAAGAAAGTACAAGAAGGTTTT
GCACCTTTAGTGGAAGGTTTTATTCGAGTGCCATTTGGTGATATTGAAGCCATCCAAGAGGCTGCCTTACAGCATCCAGA
TATTGTTGCTATTTTAATTGAACCAATCCAAGGTGAAGGTGGTATTAATACTGCACCACAAGGATTTAGCTATTTAGAAG
AAGTTCGCCAAATTTGTAACCAGCATAACTGGTTAATGATGCTAGATGAAATTCAAACTGGTAATGGCCGTACTGGTAAA
TACTTTGCGTATCAACATACGAATATCATTCCGGATGTTTTGACCACTGCAAAAGGTTTAGGTAACGGTTTTCCAGTGGG
TGCTGTAATGACTCAAGGTAAAGCGGTAGGTTTGTTAGGGCCTGGCAGTCATGGTTCTACTTATGGCGGTACAGTATTGG
GTTCTCGTGTGGTTTACACGGTAATTGATACGATCCAGAAGGAAAATGCAGTAGAGAATGCAGCAGTAGTGGGTAATTAT
ATTGTTGACCAATTACGTGCTCAATTGTCGGATAAGAATGTGCAAGTACGTGGTTTCGGTATGATGATTGGTATCCAATT
ACCTAAAGATTGTGCTGAGCTCGTTGCGATTGCTCGTGATGAATACAAACTTATTATTAACGTCACGGCAGGTTCGGTGG
TGCGTTTATTACCGCCAATTAACATGACACAAGCTCAAGCTGATATTTTGCTAGAGCGTTTAGTCGCATTAATTACCAAT
TATCTTTAA

Upstream 100 bases:

>100_bases
GCAGACGAAATTTTAGATAAATGAATGATGAGACTTTTCATCAGTGCAAGTTTTTGTTTATATAAACCCTTCTTAAAACC
TCATACAGACAGAGTTCGTG

Downstream 100 bases:

>100_bases
GTTTAAAAACAATAAAAATGGGCGTTAATCGCCCATTTTTATTTTTGTATTTAGCCTGAAATATATTGTTTTAATTGTTC
AATCAAAACCTTCTGGTCTT

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 402; Mature: 401

Protein sequence:

>402_residues
MTDITLAPVQPDQPTHLMATYGRQAISFVRGRGAYLYTKDGTEYLDALTGIAVCGLGHAHPAIAEAIAEQAATLVHTSNL
FEIPWQTAAAQKLAEVSGMEEIFFSNSGAESNEGAIKIARKFGTQQGISLPKIIVAEQSFHGRTLATLSATGNKKVQEGF
APLVEGFIRVPFGDIEAIQEAALQHPDIVAILIEPIQGEGGINTAPQGFSYLEEVRQICNQHNWLMMLDEIQTGNGRTGK
YFAYQHTNIIPDVLTTAKGLGNGFPVGAVMTQGKAVGLLGPGSHGSTYGGTVLGSRVVYTVIDTIQKENAVENAAVVGNY
IVDQLRAQLSDKNVQVRGFGMMIGIQLPKDCAELVAIARDEYKLIINVTAGSVVRLLPPINMTQAQADILLERLVALITN
YL

Sequences:

>Translated_402_residues
MTDITLAPVQPDQPTHLMATYGRQAISFVRGRGAYLYTKDGTEYLDALTGIAVCGLGHAHPAIAEAIAEQAATLVHTSNL
FEIPWQTAAAQKLAEVSGMEEIFFSNSGAESNEGAIKIARKFGTQQGISLPKIIVAEQSFHGRTLATLSATGNKKVQEGF
APLVEGFIRVPFGDIEAIQEAALQHPDIVAILIEPIQGEGGINTAPQGFSYLEEVRQICNQHNWLMMLDEIQTGNGRTGK
YFAYQHTNIIPDVLTTAKGLGNGFPVGAVMTQGKAVGLLGPGSHGSTYGGTVLGSRVVYTVIDTIQKENAVENAAVVGNY
IVDQLRAQLSDKNVQVRGFGMMIGIQLPKDCAELVAIARDEYKLIINVTAGSVVRLLPPINMTQAQADILLERLVALITN
YL
>Mature_401_residues
TDITLAPVQPDQPTHLMATYGRQAISFVRGRGAYLYTKDGTEYLDALTGIAVCGLGHAHPAIAEAIAEQAATLVHTSNLF
EIPWQTAAAQKLAEVSGMEEIFFSNSGAESNEGAIKIARKFGTQQGISLPKIIVAEQSFHGRTLATLSATGNKKVQEGFA
PLVEGFIRVPFGDIEAIQEAALQHPDIVAILIEPIQGEGGINTAPQGFSYLEEVRQICNQHNWLMMLDEIQTGNGRTGKY
FAYQHTNIIPDVLTTAKGLGNGFPVGAVMTQGKAVGLLGPGSHGSTYGGTVLGSRVVYTVIDTIQKENAVENAAVVGNYI
VDQLRAQLSDKNVQVRGFGMMIGIQLPKDCAELVAIARDEYKLIINVTAGSVVRLLPPINMTQAQADILLERLVALITNY
L

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=374, Percent_Identity=34.7593582887701, Blast_Score=221, Evalue=7e-58,
Organism=Homo sapiens, GI284507298, Length=288, Percent_Identity=37.8472222222222, Blast_Score=187, Evalue=2e-47,
Organism=Homo sapiens, GI13994255, Length=442, Percent_Identity=28.7330316742081, Blast_Score=160, Evalue=1e-39,
Organism=Homo sapiens, GI37574042, Length=420, Percent_Identity=26.6666666666667, Blast_Score=141, Evalue=8e-34,
Organism=Homo sapiens, GI24119277, Length=421, Percent_Identity=26.8408551068884, Blast_Score=132, Evalue=8e-31,
Organism=Homo sapiens, GI226442705, Length=420, Percent_Identity=25.7142857142857, Blast_Score=129, Evalue=6e-30,
Organism=Homo sapiens, GI226442709, Length=385, Percent_Identity=26.7532467532467, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI188536080, Length=433, Percent_Identity=24.0184757505774, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI38679950, Length=433, Percent_Identity=24.0184757505774, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI38679946, Length=433, Percent_Identity=24.0184757505774, Blast_Score=103, Evalue=4e-22,
Organism=Escherichia coli, GI1788044, Length=380, Percent_Identity=37.6315789473684, Blast_Score=255, Evalue=4e-69,
Organism=Escherichia coli, GI1789759, Length=372, Percent_Identity=37.6344086021505, Blast_Score=245, Evalue=3e-66,
Organism=Escherichia coli, GI145693181, Length=391, Percent_Identity=32.7365728900256, Blast_Score=202, Evalue=4e-53,
Organism=Escherichia coli, GI1787560, Length=396, Percent_Identity=32.0707070707071, Blast_Score=170, Evalue=1e-43,
Organism=Escherichia coli, GI1789016, Length=393, Percent_Identity=31.0432569974555, Blast_Score=163, Evalue=2e-41,
Organism=Escherichia coli, GI1786349, Length=285, Percent_Identity=28.0701754385965, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1786991, Length=290, Percent_Identity=26.551724137931, Blast_Score=94, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI25144271, Length=387, Percent_Identity=31.0077519379845, Blast_Score=221, Evalue=5e-58,
Organism=Caenorhabditis elegans, GI32564660, Length=436, Percent_Identity=31.1926605504587, Blast_Score=179, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI25144274, Length=271, Percent_Identity=33.5793357933579, Blast_Score=175, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI71992977, Length=426, Percent_Identity=28.169014084507, Blast_Score=143, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17541228, Length=382, Percent_Identity=25.6544502617801, Blast_Score=95, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI71981843, Length=169, Percent_Identity=26.6272189349112, Blast_Score=85, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6324432, Length=381, Percent_Identity=34.6456692913386, Blast_Score=212, Evalue=7e-56,
Organism=Saccharomyces cerevisiae, GI6323470, Length=404, Percent_Identity=32.1782178217822, Blast_Score=197, Evalue=3e-51,
Organism=Saccharomyces cerevisiae, GI6321456, Length=453, Percent_Identity=23.3995584988962, Blast_Score=90, Evalue=7e-19,
Organism=Saccharomyces cerevisiae, GI6324386, Length=336, Percent_Identity=26.4880952380952, Blast_Score=89, Evalue=9e-19,
Organism=Drosophila melanogaster, GI21357415, Length=376, Percent_Identity=34.3085106382979, Blast_Score=224, Evalue=9e-59,
Organism=Drosophila melanogaster, GI28574759, Length=427, Percent_Identity=28.5714285714286, Blast_Score=163, Evalue=2e-40,
Organism=Drosophila melanogaster, GI161085790, Length=419, Percent_Identity=27.9236276849642, Blast_Score=158, Evalue=6e-39,
Organism=Drosophila melanogaster, GI21356575, Length=416, Percent_Identity=27.8846153846154, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI281366494, Length=428, Percent_Identity=24.0654205607477, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24667139, Length=428, Percent_Identity=24.0654205607477, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24667143, Length=428, Percent_Identity=24.0654205607477, Blast_Score=90, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 43099; Mature: 42968

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDITLAPVQPDQPTHLMATYGRQAISFVRGRGAYLYTKDGTEYLDALTGIAVCGLGHAH
CCCCEECCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHCCCCCC
PAIAEAIAEQAATLVHTSNLFEIPWQTAAAQKLAEVSGMEEIFFSNSGAESNEGAIKIAR
HHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHCCHHHHHCCCCCCCCCCCHHHHHH
KFGTQQGISLPKIIVAEQSFHGRTLATLSATGNKKVQEGFAPLVEGFIRVPFGDIEAIQE
HHCCCCCCCCCEEEEECCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHHH
AALQHPDIVAILIEPIQGEGGINTAPQGFSYLEEVRQICNQHNWLMMLDEIQTGNGRTGK
HHHCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCC
YFAYQHTNIIPDVLTTAKGLGNGFPVGAVMTQGKAVGLLGPGSHGSTYGGTVLGSRVVYT
EEEEECCCCCHHHHHHHHHCCCCCCCHHEEECCCEEEEECCCCCCCCCCCHHHHHHHHHH
VIDTIQKENAVENAAVVGNYIVDQLRAQLSDKNVQVRGFGMMIGIQLPKDCAELVAIARD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEECCHHHHHHHHHCCC
EYKLIINVTAGSVVRLLPPINMTQAQADILLERLVALITNYL
CEEEEEEECCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TDITLAPVQPDQPTHLMATYGRQAISFVRGRGAYLYTKDGTEYLDALTGIAVCGLGHAH
CCCEECCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHCCCCCC
PAIAEAIAEQAATLVHTSNLFEIPWQTAAAQKLAEVSGMEEIFFSNSGAESNEGAIKIAR
HHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHCCHHHHHCCCCCCCCCCCHHHHHH
KFGTQQGISLPKIIVAEQSFHGRTLATLSATGNKKVQEGFAPLVEGFIRVPFGDIEAIQE
HHCCCCCCCCCEEEEECCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHHH
AALQHPDIVAILIEPIQGEGGINTAPQGFSYLEEVRQICNQHNWLMMLDEIQTGNGRTGK
HHHCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCC
YFAYQHTNIIPDVLTTAKGLGNGFPVGAVMTQGKAVGLLGPGSHGSTYGGTVLGSRVVYT
EEEEECCCCCHHHHHHHHHCCCCCCCHHEEECCCEEEEECCCCCCCCCCCHHHHHHHHHH
VIDTIQKENAVENAAVVGNYIVDQLRAQLSDKNVQVRGFGMMIGIQLPKDCAELVAIARD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEECCHHHHHHHHHCCC
EYKLIINVTAGSVVRLLPPINMTQAQADILLERLVALITNYL
CEEEEEEECCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12700255 [H]