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The map label for this gene is argC

Identifier: 213157556

GI number: 213157556

Start: 2331973

End: 2333022

Strand: Reverse

Name: argC

Synonym: AB57_2247

Alternate gene names: 213157556

Gene position: 2333022-2331973 (Counterclockwise)

Preceding gene: 213157557

Following gene: 213157555

Centisome position: 57.6

GC content: 39.05

Gene sequence:

>1050_bases
GTGATTTCTGTCGGAATTGTTGGTGGAACTGGTTATACAGGCGTTGAACTATTACGTATTTTATTACGGCATCCAAAAGC
GCAGGTTCGAGTTCTGACTTCACGTACAGAAGCGGGCAAACCAGTTGCTGATATGTTCCCAAACTTACGTGGGCATACAG
ATCTTCAATTTTCAGATTTAAACATTGATGCATTAAAAGAATGTGATGTTGTATTTTTTGCAACTCCTCATGGTGTTGCG
ATGCAACATGCGAAAGATTTGATTGCGGCAGGCACCAAAGTTATTGATTTAGCTGCTGACTTTCGTTTACAGAATCTTGA
GCAATTTGAAAAGTGGTATGGTATGGAGCATGCTTGCCCAGATGTACTAAAAGATTCTGTTTATGGTTTAACCGAGTTAA
ATCGTGAAAAAATTAAGCAAGCTCAAGTCATTGGTAATCCGGGTTGTTACCCAACGACTGTTCAACTGGGCTTGGCTCCA
CTTTTAAAATCAGCACAAGCATTGATTGAAACAAAGAATATTATTATTGATGCAAAATCTGGTGTTTCTGGTGCTGGTCG
TAAAGCAAGTTTGGGCATGATTTACAGTGAAAATGCGGATAACTTTAAAGCTTATGGTGTTGCAGGCCATCGCCACCATC
CAGAGATTGTAGAGGCTTTGGAAAATATTGCAGGTAAGAAAGATGTTTTTGAGGGTCTTTTATTTGTTCCGCACCTAGTA
CCGATGATTCGCGGTATGTTAAGTACAATTTATGTAGACTTGACAGAAGCAGGTAAACAAACAGCTTTGCAAGCTTTGTA
TGAAAACTTCTATGCAAATGAAAAATTTGTAGATGTCATGCCTGCTAATAGCTCACCTGAAACTCGCAGCGTGCGTGGAG
CAAATGAATTACGTATTGCTTTGTATAAACCACAACCAAATAAACTCATTATTTTGGCGGCTCAAGATAACCTTGTAAAA
GGTGCATCTGGCCAAGCTGTACAAAATATGAACCTTATGTTTGGCTTTAATGAAGATGAAGGCTTACAAGGGATTGGTTT
ATTACCATAA

Upstream 100 bases:

>100_bases
AAATAAAAAAATTAAAATTACCAAGCATGAAATGGTTTTGTAAGCCTAGACATCCTGTCATACTACCGCAAGTATAGATT
CAAAATTTGAGGTAATGCAC

Downstream 100 bases:

>100_bases
AAAACTCTTTTTTGCTTCACACACATTTAAATTTCGATTTAAATGTGTGTCTTGACTCTGATCTTAAACACTGAGATGAC
GATGCAAAACTCGGAACAGA

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MISVGIVGGTGYTGVELLRILLRHPKAQVRVLTSRTEAGKPVADMFPNLRGHTDLQFSDLNIDALKECDVVFFATPHGVA
MQHAKDLIAAGTKVIDLAADFRLQNLEQFEKWYGMEHACPDVLKDSVYGLTELNREKIKQAQVIGNPGCYPTTVQLGLAP
LLKSAQALIETKNIIIDAKSGVSGAGRKASLGMIYSENADNFKAYGVAGHRHHPEIVEALENIAGKKDVFEGLLFVPHLV
PMIRGMLSTIYVDLTEAGKQTALQALYENFYANEKFVDVMPANSSPETRSVRGANELRIALYKPQPNKLIILAAQDNLVK
GASGQAVQNMNLMFGFNEDEGLQGIGLLP

Sequences:

>Translated_349_residues
MISVGIVGGTGYTGVELLRILLRHPKAQVRVLTSRTEAGKPVADMFPNLRGHTDLQFSDLNIDALKECDVVFFATPHGVA
MQHAKDLIAAGTKVIDLAADFRLQNLEQFEKWYGMEHACPDVLKDSVYGLTELNREKIKQAQVIGNPGCYPTTVQLGLAP
LLKSAQALIETKNIIIDAKSGVSGAGRKASLGMIYSENADNFKAYGVAGHRHHPEIVEALENIAGKKDVFEGLLFVPHLV
PMIRGMLSTIYVDLTEAGKQTALQALYENFYANEKFVDVMPANSSPETRSVRGANELRIALYKPQPNKLIILAAQDNLVK
GASGQAVQNMNLMFGFNEDEGLQGIGLLP
>Mature_349_residues
MISVGIVGGTGYTGVELLRILLRHPKAQVRVLTSRTEAGKPVADMFPNLRGHTDLQFSDLNIDALKECDVVFFATPHGVA
MQHAKDLIAAGTKVIDLAADFRLQNLEQFEKWYGMEHACPDVLKDSVYGLTELNREKIKQAQVIGNPGCYPTTVQLGLAP
LLKSAQALIETKNIIIDAKSGVSGAGRKASLGMIYSENADNFKAYGVAGHRHHPEIVEALENIAGKKDVFEGLLFVPHLV
PMIRGMLSTIYVDLTEAGKQTALQALYENFYANEKFVDVMPANSSPETRSVRGANELRIALYKPQPNKLIILAAQDNLVK
GASGQAVQNMNLMFGFNEDEGLQGIGLLP

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790396, Length=348, Percent_Identity=37.9310344827586, Blast_Score=200, Evalue=1e-52,
Organism=Saccharomyces cerevisiae, GI6320913, Length=349, Percent_Identity=30.0859598853868, Blast_Score=114, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGC_ACIB3 (B7H211)

Other databases:

- EMBL:   CP001172
- RefSeq:   YP_002325444.1
- ProteinModelPortal:   B7H211
- SMR:   B7H211
- GeneID:   7060192
- GenomeReviews:   CP001172_GR
- KEGG:   abb:ABBFA_001541
- HOGENOM:   HBG294213
- OMA:   GCFPTAS
- ProtClustDB:   PRK00436
- GO:   GO:0005737
- HAMAP:   MF_00150
- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280
- Gene3D:   G3DSA:3.40.50.720
- SMART:   SM00859
- TIGRFAMs:   TIGR01850

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC

EC number: =1.2.1.38

Molecular weight: Translated: 38012; Mature: 38012

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: PS01224 ARGC

Important sites: ACT_SITE 149-149

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISVGIVGGTGYTGVELLRILLRHPKAQVRVLTSRTEAGKPVADMFPNLRGHTDLQFSDL
CEEEEEECCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHCCCCCCCCCCEEECC
NIDALKECDVVFFATPHGVAMQHAKDLIAAGTKVIDLAADFRLQNLEQFEKWYGMEHACP
CHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCH
DVLKDSVYGLTELNREKIKQAQVIGNPGCYPTTVQLGLAPLLKSAQALIETKNIIIDAKS
HHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCEEEEECCC
GVSGAGRKASLGMIYSENADNFKAYGVAGHRHHPEIVEALENIAGKKDVFEGLLFVPHLV
CCCCCCCCEEEEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHH
PMIRGMLSTIYVDLTEAGKQTALQALYENFYANEKFVDVMPANSSPETRSVRGANELRIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCEEEEE
LYKPQPNKLIILAAQDNLVKGASGQAVQNMNLMFGFNEDEGLQGIGLLP
EECCCCCEEEEEEECCCEECCCCCCCEECCEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure
MISVGIVGGTGYTGVELLRILLRHPKAQVRVLTSRTEAGKPVADMFPNLRGHTDLQFSDL
CEEEEEECCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHCCCCCCCCCCEEECC
NIDALKECDVVFFATPHGVAMQHAKDLIAAGTKVIDLAADFRLQNLEQFEKWYGMEHACP
CHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCH
DVLKDSVYGLTELNREKIKQAQVIGNPGCYPTTVQLGLAPLLKSAQALIETKNIIIDAKS
HHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCEEEEECCC
GVSGAGRKASLGMIYSENADNFKAYGVAGHRHHPEIVEALENIAGKKDVFEGLLFVPHLV
CCCCCCCCEEEEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHH
PMIRGMLSTIYVDLTEAGKQTALQALYENFYANEKFVDVMPANSSPETRSVRGANELRIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCEEEEE
LYKPQPNKLIILAAQDNLVKGASGQAVQNMNLMFGFNEDEGLQGIGLLP
EECCCCCEEEEEEECCCEECCCCCCCEECCEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA