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The map label for this gene is pcaI [H]

Identifier: 213157493

GI number: 213157493

Start: 2264424

End: 2265095

Strand: Direct

Name: pcaI [H]

Synonym: AB57_2182

Alternate gene names: 213157493

Gene position: 2264424-2265095 (Clockwise)

Preceding gene: 213157492

Following gene: 213157494

Centisome position: 55.9

GC content: 46.73

Gene sequence:

>672_bases
ATGATTGACAAAAGTAAGTCCTCACTAAGCGAGGTTCTATCGCAGATTAAAGATGGTGCAACCATTCTGATTGGTGGTTT
TGGTACCGCAGGACAACCCGCTGAACTCATTGACGGTCTGATTGAACTTGGCGTTAAGGACCTGACCATTGTGAGCAACA
ATGCCGGTAATGGGGATTATGGTCTCGCTAAGCTGCTCAAAGCCGGTTCTATTAAAAAAGTGATTTGCTCTTTCCCACGT
CAGTCTGACTCTTATGTATTTGATGAACTGTACCGTGCCGGAAAGGTTGAGCTTGAACTGGTACCGCAAGGCAATCTGGC
GTGCCGTATTCAGGCAGCTGGTATGGGTCTTGGGGCGGTGTTTACACCAACTGGCTTTGGAACACTTTTAGCTGAAGGCA
AAGAAACCCGTCATATTGATGGGAAAGATTACGTACTCGAATATCCGATTAAAGCTGACTTTGCTTTGATTAAAGCCTAC
AAAGGCGACCGTTGGGGCAATCTGGTTTACCGTAAATCTGCACGTAACTTTGGCCCGATCATGGCCATGGCTGCTGATGT
CACCATTGCTCAGGTTTCTGAAGTGGTTGAACTCGGTGGATTAGACCCTGAGCACATTATCACCCCAGGTATTTTTGTAC
AGCATGTTGTACAAGTACAGCCCGCACAGTAA

Upstream 100 bases:

>100_bases
ACTCACAAAATTTACTCCATTTATTACTACCTTTAAGAATTTCAATAAATTTTTAGCGGTAGTAATACATCACGTTACCT
CATGCTCTAAGGTTTCTCAC

Downstream 100 bases:

>100_bases
GCAATAAGGAGAAATAACATGAGCTACCAGAAACTCAGCCGTGACCAGATTGCACAACGTGTGGCACAAGATATTCCCGA
TGGTGCCTATGTGAACTTGG

Product: 3-oxoadipate CoA-transferase subunit A

Products: NA

Alternate protein names: Beta-ketoadipate:succinyl-CoA transferase subunit A [H]

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MIDKSKSSLSEVLSQIKDGATILIGGFGTAGQPAELIDGLIELGVKDLTIVSNNAGNGDYGLAKLLKAGSIKKVICSFPR
QSDSYVFDELYRAGKVELELVPQGNLACRIQAAGMGLGAVFTPTGFGTLLAEGKETRHIDGKDYVLEYPIKADFALIKAY
KGDRWGNLVYRKSARNFGPIMAMAADVTIAQVSEVVELGGLDPEHIITPGIFVQHVVQVQPAQ

Sequences:

>Translated_223_residues
MIDKSKSSLSEVLSQIKDGATILIGGFGTAGQPAELIDGLIELGVKDLTIVSNNAGNGDYGLAKLLKAGSIKKVICSFPR
QSDSYVFDELYRAGKVELELVPQGNLACRIQAAGMGLGAVFTPTGFGTLLAEGKETRHIDGKDYVLEYPIKADFALIKAY
KGDRWGNLVYRKSARNFGPIMAMAADVTIAQVSEVVELGGLDPEHIITPGIFVQHVVQVQPAQ
>Mature_223_residues
MIDKSKSSLSEVLSQIKDGATILIGGFGTAGQPAELIDGLIELGVKDLTIVSNNAGNGDYGLAKLLKAGSIKKVICSFPR
QSDSYVFDELYRAGKVELELVPQGNLACRIQAAGMGLGAVFTPTGFGTLLAEGKETRHIDGKDYVLEYPIKADFALIKAY
KGDRWGNLVYRKSARNFGPIMAMAADVTIAQVSEVVELGGLDPEHIITPGIFVQHVVQVQPAQ

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=226, Percent_Identity=43.8053097345133, Blast_Score=194, Evalue=5e-50,
Organism=Homo sapiens, GI11545841, Length=228, Percent_Identity=44.7368421052632, Blast_Score=185, Evalue=3e-47,
Organism=Escherichia coli, GI1788551, Length=220, Percent_Identity=41.3636363636364, Blast_Score=187, Evalue=4e-49,
Organism=Caenorhabditis elegans, GI17531517, Length=237, Percent_Identity=40.9282700421941, Blast_Score=168, Evalue=2e-42,
Organism=Drosophila melanogaster, GI21358325, Length=229, Percent_Identity=41.0480349344978, Blast_Score=172, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24655794, Length=229, Percent_Identity=41.0480349344978, Blast_Score=172, Evalue=2e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.6 [H]

Molecular weight: Translated: 23810; Mature: 23810

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: PS00687 ALDEHYDE_DEHYDR_GLU ; PS01273 COA_TRANSF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDKSKSSLSEVLSQIKDGATILIGGFGTAGQPAELIDGLIELGVKDLTIVSNNAGNGDY
CCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCH
GLAKLLKAGSIKKVICSFPRQSDSYVFDELYRAGKVELELVPQGNLACRIQAAGMGLGAV
HHHHHHHCCCHHHHHHCCCCCCCCHHHHHHHHCCCEEEEEECCCCEEEEEEECCCCCCEE
FTPTGFGTLLAEGKETRHIDGKDYVLEYPIKADFALIKAYKGDRWGNLVYRKSARNFGPI
ECCCCCHHHHHCCCCCCCCCCCCEEEECCCCCCEEEEEECCCCCCCCEEEECCCCCCCCH
MAMAADVTIAQVSEVVELGGLDPEHIITPGIFVQHVVQVQPAQ
HHHHHHHHHHHHHHHHHHCCCCHHHEECCHHHHHHHHHCCCCC
>Mature Secondary Structure
MIDKSKSSLSEVLSQIKDGATILIGGFGTAGQPAELIDGLIELGVKDLTIVSNNAGNGDY
CCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCH
GLAKLLKAGSIKKVICSFPRQSDSYVFDELYRAGKVELELVPQGNLACRIQAAGMGLGAV
HHHHHHHCCCHHHHHHCCCCCCCCHHHHHHHHCCCEEEEEECCCCEEEEEEECCCCCCEE
FTPTGFGTLLAEGKETRHIDGKDYVLEYPIKADFALIKAYKGDRWGNLVYRKSARNFGPI
ECCCCCHHHHHCCCCCCCCCCCCEEEECCCCCCEEEEEECCCCCCCCEEEECCCCCCCCH
MAMAADVTIAQVSEVVELGGLDPEHIITPGIFVQHVVQVQPAQ
HHHHHHHHHHHHHHHHHHCCCCHHHEECCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8063101; 8125318 [H]