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The map label for this gene is dgoR [H]

Identifier: 213157487

GI number: 213157487

Start: 2259113

End: 2259829

Strand: Direct

Name: dgoR [H]

Synonym: AB57_2176

Alternate gene names: 213157487

Gene position: 2259113-2259829 (Clockwise)

Preceding gene: 213157486

Following gene: 213157490

Centisome position: 55.77

GC content: 38.21

Gene sequence:

>717_bases
ATGAGTAAAGCTGACTATAAAAATCCTATTCCAAGCAAAAGCCAACATGCATTAATTGTTCAACAATTGGGATTAAAAAT
CGTTTCTGGAGAAATCTCAGAAAATGAAAAACTCCCAAGTGAAGTTGATTTATGTGAGGAATATAAAGTCAGCCGCCCTG
TCTTTCGCGAAGCTATACGTGTTTTAAATGCGAAAGGCTTAACATATTCAAGGCCCAAAATCGGAACAGTAGTTCGACCT
AAAGAAGAATGGCATTTACTCGACCCAGATGTACTGTTCTGGTTGATTCAAACCACGCCTGAGCACGAGTTTTTTAAAAC
ACTTTCTACCGTACGACGCGTTTTAGAACCGGAGTTAGCCTATATTGCGGCAAGTACAGCAAATGAAGAAGATATTGAGC
GTATTAAGCAAGCCTATGAAGGAATGGAAAAGGCGACAACAGTTGAAGAGTTTATAGAACCCGATATCCAGTTTCACTTA
GCAATTGCCAAAGCAACGCATAATGACTTATTGGCTTATATGTCAAAAATGCTGGTTTTACCTTTGCAGCAATCGATTCA
AGTCACTAGTCTGCGCCCAAATTTACAAGGTCATTCATTACCAAGACATAAAGCAATTTTGACAGCAATTGAAAATAAAG
ATCCGCTCTCTGCTCGTCATGCTTCACTGGTTCAGCTAGACGATACTAAAATGGCTTATGATTTAATTAAAAAATAA

Upstream 100 bases:

>100_bases
CACGTCATTCCCATTAATATTTATTCTTGAAAAAGATGATCTTGTTAAAACACAAGGTCATCTATACCATAGGATATTCA
ACATGTCGTAATAGTGAAAT

Downstream 100 bases:

>100_bases
TTTTCTCTATGTATTAGAAAAAGCCTGCTGACTCCAAATTAAAGTGATCAGGCTTTTTATTTATAAATTAGAACACCTTT
TTTACAGAGACTGTAAAAGT

Product: transcriptional regulator, GntR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 237

Protein sequence:

>238_residues
MSKADYKNPIPSKSQHALIVQQLGLKIVSGEISENEKLPSEVDLCEEYKVSRPVFREAIRVLNAKGLTYSRPKIGTVVRP
KEEWHLLDPDVLFWLIQTTPEHEFFKTLSTVRRVLEPELAYIAASTANEEDIERIKQAYEGMEKATTVEEFIEPDIQFHL
AIAKATHNDLLAYMSKMLVLPLQQSIQVTSLRPNLQGHSLPRHKAILTAIENKDPLSARHASLVQLDDTKMAYDLIKK

Sequences:

>Translated_238_residues
MSKADYKNPIPSKSQHALIVQQLGLKIVSGEISENEKLPSEVDLCEEYKVSRPVFREAIRVLNAKGLTYSRPKIGTVVRP
KEEWHLLDPDVLFWLIQTTPEHEFFKTLSTVRRVLEPELAYIAASTANEEDIERIKQAYEGMEKATTVEEFIEPDIQFHL
AIAKATHNDLLAYMSKMLVLPLQQSIQVTSLRPNLQGHSLPRHKAILTAIENKDPLSARHASLVQLDDTKMAYDLIKK
>Mature_237_residues
SKADYKNPIPSKSQHALIVQQLGLKIVSGEISENEKLPSEVDLCEEYKVSRPVFREAIRVLNAKGLTYSRPKIGTVVRPK
EEWHLLDPDVLFWLIQTTPEHEFFKTLSTVRRVLEPELAYIAASTANEEDIERIKQAYEGMEKATTVEEFIEPDIQFHLA
IAKATHNDLLAYMSKMLVLPLQQSIQVTSLRPNLQGHSLPRHKAILTAIENKDPLSARHASLVQLDDTKMAYDLIKK

Specific function: Repressor for the dgoRKAT operon. Binds D-galactonate as an inducer [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994955, Length=211, Percent_Identity=32.7014218009479, Blast_Score=110, Evalue=6e-26,
Organism=Escherichia coli, GI48994961, Length=164, Percent_Identity=28.6585365853659, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1786303, Length=212, Percent_Identity=33.0188679245283, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI1790780, Length=212, Percent_Identity=34.4339622641509, Blast_Score=70, Evalue=9e-14,
Organism=Escherichia coli, GI1790032, Length=201, Percent_Identity=30.8457711442786, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1789353, Length=206, Percent_Identity=29.6116504854369, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 27080; Mature: 26948

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKADYKNPIPSKSQHALIVQQLGLKIVSGEISENEKLPSEVDLCEEYKVSRPVFREAIR
CCCCCCCCCCCCCCHHHHHHHHHCCEEEECCCCCCCCCCHHHHHHHHHCCCCHHHHHHHH
VLNAKGLTYSRPKIGTVVRPKEEWHLLDPDVLFWLIQTTPEHEFFKTLSTVRRVLEPELA
HHHCCCCEECCCCCCCEECCHHHCEECCHHHEEEEECCCCCHHHHHHHHHHHHHHCCHHH
YIAASTANEEDIERIKQAYEGMEKATTVEEFIEPDIQFHLAIAKATHNDLLAYMSKMLVL
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHH
PLQQSIQVTSLRPNLQGHSLPRHKAILTAIENKDPLSARHASLVQLDDTKMAYDLIKK
HHHHCEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHEEECCHHHHHHHHCC
>Mature Secondary Structure 
SKADYKNPIPSKSQHALIVQQLGLKIVSGEISENEKLPSEVDLCEEYKVSRPVFREAIR
CCCCCCCCCCCCCHHHHHHHHHCCEEEECCCCCCCCCCHHHHHHHHHCCCCHHHHHHHH
VLNAKGLTYSRPKIGTVVRPKEEWHLLDPDVLFWLIQTTPEHEFFKTLSTVRRVLEPELA
HHHCCCCEECCCCCCCEECCHHHCEECCHHHEEEEECCCCCHHHHHHHHHHHHHHCCHHH
YIAASTANEEDIERIKQAYEGMEKATTVEEFIEPDIQFHLAIAKATHNDLLAYMSKMLVL
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHH
PLQQSIQVTSLRPNLQGHSLPRHKAILTAIENKDPLSARHASLVQLDDTKMAYDLIKK
HHHHCEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHEEECCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]