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The map label for this gene is ttuB [H]

Identifier: 213157447

GI number: 213157447

Start: 2219032

End: 2220372

Strand: Direct

Name: ttuB [H]

Synonym: AB57_2136

Alternate gene names: 213157447

Gene position: 2219032-2220372 (Clockwise)

Preceding gene: 213157446

Following gene: 213157457

Centisome position: 54.78

GC content: 38.63

Gene sequence:

>1341_bases
ATGAAAAATGATATATCTATATCGGAAGTAGAAAAGTCAACGATCCGTAAACTTTCTTTCCGTATTCTTCCTTTCCTCAT
TCTTTGTTATTTCATCGCTTATATTGATCGGGTGAATATTGGTTTCGCCGCTTTAACCATGAACCAAGAAATTGGTTTAA
CTGCTACTGCCTTTGGTTTTGGTGCGACATTATTTTTTATTGCATATGTCATATTTGAAATTCCAAGTAACATGGCTATG
GAAAAGCTAGGTGCACGTATCTGGATTGCCAGAATCATGATTACTTGGGGCATTGTCGGTTGCTGTACTGCCTTCATTAC
TGGCCCTATTTCATATGCAATTTCACGCTTTTTACTTGGTGCTGCCGAAGCCGGATTTTTCCCAGGCGTATTACTGTATT
TAACACTATGGTTCCCTAAACGATATATGGCTCGAATTGTTGCCGTATTTATGGTTGCGATTCCTTTATCTAACTTTATT
GGTTCACCATTATCTGCCTTATTGTTAGGCTTGCATGGTTTACTGGGCTTAAGTGGATGGCAAGTGCTTTTAATTCTTGA
AGCATTACCTGCAATCCTTCTTGGTTTGTTGTGCCTTGTATGGCTGCCGAATACCGCGAACAATGTGAAATGGTTAAATC
AAGAAGAAAAGGACTGGTTATCAAGCACTTTAACTTTTGAAAAAAATCAATTGTTGAACTCTGAAAAACAAGACAGTGCC
GAACAGAAAAAGAGTAAGTTCAAGCTGCTGATTACCAATAAATATCTATGGTTCTTTGCAATTATTTATGCAGGAAGTTC
AGCAACCAGCAATATTTTATCGTTATGGATGCCTCAGATTTTAAAAGCCTTCCATCTAACTGCCATGCAGACAGGTCTTT
TAAATATGATTCCTTTTGGTTTAGCTGCCGCTTTCATGATTGTTTGGGGCGTACATGCCGATAAAAGTGGCAATAAAAGT
CTCAACACAGCTATACCGTTATTTGTGACCAGTTTTGGTTTGCTTCTTACTATTTTTACTTCATCTTTAACCTTGAGCTT
ACTTTTATTCTCACTCGTTTTGATGGGTAACTATGCCATTAAAGGTCCTTTCTGGGCGTTGGTTTCTGAGCGCTTACCAC
CTACTTTAGTGGCTGTAGGTATTGCAGCGGTGAATACGATTGCGCATATCGGTACTGGGCTTATGAACTCTATTATGGGT
ATTGTAAAAGATTATTCGGGTAGCTTCCCTATTTCTCTTTTACCGTTATGTATGCTTACATTTACGGGTGCCATGATTGC
GTTGTATTTGGGAAGAAAACCGACATTGCCAAAAGCGCAAAAGGTTCAAAAAGCAGTTTAG

Upstream 100 bases:

>100_bases
AGCTTTTAAACAGATTGTGTTTGATAAACACGAGCAATGTTTAATTTTAAATCAGAACCCTACCGAGCTGTTTGGTTTCT
CACGTACATAAGGAGTATGT

Downstream 100 bases:

>100_bases
GTTTTAGAAATAAAAGATTTAATCAAAAGAGACCATTAATGGTCTCTTTTTTAATTTATAAGGAACTTAAATTCCCTTAC
TTAAAAACACACTCAATTAG

Product: transporter, anion:cation symporter (ACS) family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MKNDISISEVEKSTIRKLSFRILPFLILCYFIAYIDRVNIGFAALTMNQEIGLTATAFGFGATLFFIAYVIFEIPSNMAM
EKLGARIWIARIMITWGIVGCCTAFITGPISYAISRFLLGAAEAGFFPGVLLYLTLWFPKRYMARIVAVFMVAIPLSNFI
GSPLSALLLGLHGLLGLSGWQVLLILEALPAILLGLLCLVWLPNTANNVKWLNQEEKDWLSSTLTFEKNQLLNSEKQDSA
EQKKSKFKLLITNKYLWFFAIIYAGSSATSNILSLWMPQILKAFHLTAMQTGLLNMIPFGLAAAFMIVWGVHADKSGNKS
LNTAIPLFVTSFGLLLTIFTSSLTLSLLLFSLVLMGNYAIKGPFWALVSERLPPTLVAVGIAAVNTIAHIGTGLMNSIMG
IVKDYSGSFPISLLPLCMLTFTGAMIALYLGRKPTLPKAQKVQKAV

Sequences:

>Translated_446_residues
MKNDISISEVEKSTIRKLSFRILPFLILCYFIAYIDRVNIGFAALTMNQEIGLTATAFGFGATLFFIAYVIFEIPSNMAM
EKLGARIWIARIMITWGIVGCCTAFITGPISYAISRFLLGAAEAGFFPGVLLYLTLWFPKRYMARIVAVFMVAIPLSNFI
GSPLSALLLGLHGLLGLSGWQVLLILEALPAILLGLLCLVWLPNTANNVKWLNQEEKDWLSSTLTFEKNQLLNSEKQDSA
EQKKSKFKLLITNKYLWFFAIIYAGSSATSNILSLWMPQILKAFHLTAMQTGLLNMIPFGLAAAFMIVWGVHADKSGNKS
LNTAIPLFVTSFGLLLTIFTSSLTLSLLLFSLVLMGNYAIKGPFWALVSERLPPTLVAVGIAAVNTIAHIGTGLMNSIMG
IVKDYSGSFPISLLPLCMLTFTGAMIALYLGRKPTLPKAQKVQKAV
>Mature_446_residues
MKNDISISEVEKSTIRKLSFRILPFLILCYFIAYIDRVNIGFAALTMNQEIGLTATAFGFGATLFFIAYVIFEIPSNMAM
EKLGARIWIARIMITWGIVGCCTAFITGPISYAISRFLLGAAEAGFFPGVLLYLTLWFPKRYMARIVAVFMVAIPLSNFI
GSPLSALLLGLHGLLGLSGWQVLLILEALPAILLGLLCLVWLPNTANNVKWLNQEEKDWLSSTLTFEKNQLLNSEKQDSA
EQKKSKFKLLITNKYLWFFAIIYAGSSATSNILSLWMPQILKAFHLTAMQTGLLNMIPFGLAAAFMIVWGVHADKSGNKS
LNTAIPLFVTSFGLLLTIFTSSLTLSLLLFSLVLMGNYAIKGPFWALVSERLPPTLVAVGIAAVNTIAHIGTGLMNSIMG
IVKDYSGSFPISLLPLCMLTFTGAMIALYLGRKPTLPKAQKVQKAV

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Escherichia coli, GI87082071, Length=434, Percent_Identity=29.9539170506912, Blast_Score=196, Evalue=4e-51,
Organism=Escherichia coli, GI2367379, Length=439, Percent_Identity=23.6902050113895, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI87082320, Length=408, Percent_Identity=22.5490196078431, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1789152, Length=433, Percent_Identity=20.7852193995381, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6321698, Length=311, Percent_Identity=23.4726688102894, Blast_Score=87, Evalue=7e-18,
Organism=Saccharomyces cerevisiae, GI6323032, Length=300, Percent_Identity=24, Blast_Score=85, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6322025, Length=192, Percent_Identity=23.9583333333333, Blast_Score=81, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6319876, Length=304, Percent_Identity=22.0394736842105, Blast_Score=70, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6322973, Length=278, Percent_Identity=22.6618705035971, Blast_Score=67, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6319250, Length=328, Percent_Identity=22.8658536585366, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48980; Mature: 48980

Theoretical pI: Translated: 10.01; Mature: 10.01

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNDISISEVEKSTIRKLSFRILPFLILCYFIAYIDRVNIGFAALTMNQEIGLTATAFGF
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEHHHHH
GATLFFIAYVIFEIPSNMAMEKLGARIWIARIMITWGIVGCCTAFITGPISYAISRFLLG
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAEAGFFPGVLLYLTLWFPKRYMARIVAVFMVAIPLSNFIGSPLSALLLGLHGLLGLSGW
HHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHH
QVLLILEALPAILLGLLCLVWLPNTANNVKWLNQEEKDWLSSTLTFEKNQLLNSEKQDSA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHH
EQKKSKFKLLITNKYLWFFAIIYAGSSATSNILSLWMPQILKAFHLTAMQTGLLNMIPFG
HHHHHCEEEEEECHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAAAFMIVWGVHADKSGNKSLNTAIPLFVTSFGLLLTIFTSSLTLSLLLFSLVLMGNYAI
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
KGPFWALVSERLPPTLVAVGIAAVNTIAHIGTGLMNSIMGIVKDYSGSFPISLLPLCMLT
CCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
FTGAMIALYLGRKPTLPKAQKVQKAV
HHHHHHHHHHCCCCCCCHHHHHHHCC
>Mature Secondary Structure
MKNDISISEVEKSTIRKLSFRILPFLILCYFIAYIDRVNIGFAALTMNQEIGLTATAFGF
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEHHHHH
GATLFFIAYVIFEIPSNMAMEKLGARIWIARIMITWGIVGCCTAFITGPISYAISRFLLG
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAEAGFFPGVLLYLTLWFPKRYMARIVAVFMVAIPLSNFIGSPLSALLLGLHGLLGLSGW
HHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHH
QVLLILEALPAILLGLLCLVWLPNTANNVKWLNQEEKDWLSSTLTFEKNQLLNSEKQDSA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHH
EQKKSKFKLLITNKYLWFFAIIYAGSSATSNILSLWMPQILKAFHLTAMQTGLLNMIPFG
HHHHHCEEEEEECHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAAAFMIVWGVHADKSGNKSLNTAIPLFVTSFGLLLTIFTSSLTLSLLLFSLVLMGNYAI
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
KGPFWALVSERLPPTLVAVGIAAVNTIAHIGTGLMNSIMGIVKDYSGSFPISLLPLCMLT
CCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
FTGAMIALYLGRKPTLPKAQKVQKAV
HHHHHHHHHHCCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8672817 [H]