BacMap

Definition	Acinetobacter baumannii AB0057, complete genome.
Accession	NC_011586
Length	4,050,513

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The map label for this gene is limC [H]

Identifier: 213157401

GI number: 213157401

Start: 2169146

End: 2169988

Strand: Direct

Name: limC [H]

Synonym: AB57_2090

Alternate gene names: 213157401

Gene position: 2169146-2169988 (Clockwise)

Preceding gene: 213157400

Following gene: 213157403

Centisome position: 53.55

GC content: 41.4

Gene sequence:

>843_bases
ATGTCTAAATACAAATTAAAAGATAAAGTTGTCGTAATTACAGGTTCAACAGGTGGACTAGGACTTGCGATTGCCCAAGC
ATTACAAGCGAAAGGCGCAAAACTAGCACTCCTAGATTTAGACCTTAACAAAGTTGAAAGTCAGGCAAAACAGCTAGGTG
GGCAAAGCATTGCCGCAGGTTGGGTGGCCGATGTACGCTCTTTGGAAAGCCTAGAAATGGCTATGGCAAATGCAGCTCAA
CACTTCGGTAAAATTGACGTGGTGATTGCAAATGCTGGCATAGCTACAACAGAAGCACTAGAACATATGGCTCCTGAAAC
CTTTGAGCGAACCATCGATATTAACCTGACTGGAGTATTTCGTACTTTCCGCGCAGCTATACCGTATGTAAAACAAACTC
AGGGATACTTACTGGCTGTATCTTCAATGGCAGCTTTCGTCCACTCCCCGTTAAACACTCACTATACTTCGAGTAAAGCA
GGCGTTTGGGCTTTATGTGATAGCCTTCGTCTAGAATTAAAATATTTAAATATAGGCGTTGGTAGCCTTCATCCGACCTT
CTTTAAGACCCCAATGATGGACAGTATTCAAAATGACCCAGCAGGTAAAGCTGTGTGGAAAGGCAACTCGGGTATTTGGA
AATATATCTCTATTGAAGAAGTTATCTCGGGTGTAGTTGAAAGCATAGAACGGCGTAAAGATATGACAGTTGTACCTAAA
ATAAATACGCCGATTGCGAAAGCACCCGCATTGTTTAGAAATGTGATTGAGTTTCTAGGTTTCAACCGTAAACAGCTTAA
ACAAACCATGCTTTTGGCAGAAAAAAACCATAATTCATTTTAA

Upstream 100 bases:

>100_bases
ATTGCAGGGATTACTTCAACAACTTGAAAGTGAATCTAAACCTGTCCAGAAATAATCCATTGCCTTAAAGCCCATTTATA
AAAATGTCTGGAAATCTGAT

Downstream 100 bases:

>100_bases
ATCTTTAAAAACACGGATGTTGTTGAGATATCCGTGTCTATTTAATTAGCAGCAAAACTCTAATCCTTGGCTCCAACCAT
AAGTCTTATGAGCAGCTACT

Product: short-chain dehydrogenase/reductase

Products: NA

Alternate protein names: (4R,6S)-carveol dehydrogenase; CDH; Carveol dehydrogenase [H]

Number of amino acids: Translated: 280; Mature: 279

Protein sequence:

>280_residues
MSKYKLKDKVVVITGSTGGLGLAIAQALQAKGAKLALLDLDLNKVESQAKQLGGQSIAAGWVADVRSLESLEMAMANAAQ
HFGKIDVVIANAGIATTEALEHMAPETFERTIDINLTGVFRTFRAAIPYVKQTQGYLLAVSSMAAFVHSPLNTHYTSSKA
GVWALCDSLRLELKYLNIGVGSLHPTFFKTPMMDSIQNDPAGKAVWKGNSGIWKYISIEEVISGVVESIERRKDMTVVPK
INTPIAKAPALFRNVIEFLGFNRKQLKQTMLLAEKNHNSF

Sequences:

>Translated_280_residues
MSKYKLKDKVVVITGSTGGLGLAIAQALQAKGAKLALLDLDLNKVESQAKQLGGQSIAAGWVADVRSLESLEMAMANAAQ
HFGKIDVVIANAGIATTEALEHMAPETFERTIDINLTGVFRTFRAAIPYVKQTQGYLLAVSSMAAFVHSPLNTHYTSSKA
GVWALCDSLRLELKYLNIGVGSLHPTFFKTPMMDSIQNDPAGKAVWKGNSGIWKYISIEEVISGVVESIERRKDMTVVPK
INTPIAKAPALFRNVIEFLGFNRKQLKQTMLLAEKNHNSF
>Mature_279_residues
SKYKLKDKVVVITGSTGGLGLAIAQALQAKGAKLALLDLDLNKVESQAKQLGGQSIAAGWVADVRSLESLEMAMANAAQH
FGKIDVVIANAGIATTEALEHMAPETFERTIDINLTGVFRTFRAAIPYVKQTQGYLLAVSSMAAFVHSPLNTHYTSSKAG
VWALCDSLRLELKYLNIGVGSLHPTFFKTPMMDSIQNDPAGKAVWKGNSGIWKYISIEEVISGVVESIERRKDMTVVPKI
NTPIAKAPALFRNVIEFLGFNRKQLKQTMLLAEKNHNSF

Specific function: Catalyzes the oxidation of carveol to carvone, with a strong stereoselectivity since it efficiently converts only the (6S)-stereoisomers, of which (-)-(4R,6S)-trans-carveol is the better substrate. Displays a broad substrate specificity with a preference

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI4758504, Length=204, Percent_Identity=33.3333333333333, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI83715985, Length=204, Percent_Identity=31.8627450980392, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI32483357, Length=188, Percent_Identity=31.9148936170213, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI20149619, Length=264, Percent_Identity=26.8939393939394, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI15277342, Length=205, Percent_Identity=28.2926829268293, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI19743808, Length=211, Percent_Identity=31.2796208530806, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI4504505, Length=198, Percent_Identity=28.7878787878788, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI5031737, Length=211, Percent_Identity=27.4881516587678, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI126723191, Length=182, Percent_Identity=31.8681318681319, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI150247226, Length=193, Percent_Identity=32.6424870466321, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI33667109, Length=190, Percent_Identity=28.4210526315789, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI31542939, Length=201, Percent_Identity=28.3582089552239, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI40254992, Length=205, Percent_Identity=25.8536585365854, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI4503817, Length=188, Percent_Identity=28.1914893617021, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI210032110, Length=236, Percent_Identity=23.3050847457627, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI7706318, Length=208, Percent_Identity=25, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI157739938, Length=267, Percent_Identity=22.4719101123595, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI7705925, Length=233, Percent_Identity=23.6051502145923, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI44680136, Length=186, Percent_Identity=25.8064516129032, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI44680133, Length=186, Percent_Identity=25.8064516129032, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI17738292, Length=186, Percent_Identity=25.8064516129032, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI142976729, Length=238, Percent_Identity=25.2100840336134, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI223718074, Length=200, Percent_Identity=25, Blast_Score=65, Evalue=6e-11,
Organism=Homo sapiens, GI40807363, Length=239, Percent_Identity=23.0125523012552, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI109715829, Length=179, Percent_Identity=27.9329608938547, Blast_Score=65, Evalue=9e-11,
Organism=Homo sapiens, GI19923817, Length=189, Percent_Identity=25.9259259259259, Blast_Score=65, Evalue=1e-10,
Organism=Escherichia coli, GI87082100, Length=201, Percent_Identity=32.8358208955224, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787335, Length=208, Percent_Identity=27.4038461538462, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1789057, Length=195, Percent_Identity=28.7179487179487, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790717, Length=202, Percent_Identity=28.2178217821782, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1789208, Length=202, Percent_Identity=24.7524752475248, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87082160, Length=202, Percent_Identity=22.7722772277228, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17567345, Length=245, Percent_Identity=25.7142857142857, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17508895, Length=245, Percent_Identity=26.530612244898, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17507613, Length=211, Percent_Identity=31.2796208530806, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI32563809, Length=211, Percent_Identity=31.2796208530806, Blast_Score=81, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI25147288, Length=194, Percent_Identity=28.8659793814433, Blast_Score=81, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17562910, Length=201, Percent_Identity=28.8557213930348, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17538182, Length=203, Percent_Identity=27.0935960591133, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI193203117, Length=242, Percent_Identity=25.2066115702479, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI193203115, Length=241, Percent_Identity=24.4813278008299, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17568967, Length=195, Percent_Identity=29.2307692307692, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17559104, Length=199, Percent_Identity=26.6331658291457, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17564282, Length=248, Percent_Identity=24.1935483870968, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17560332, Length=202, Percent_Identity=28.7128712871287, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17538486, Length=197, Percent_Identity=27.4111675126904, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI115534694, Length=245, Percent_Identity=27.7551020408163, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17560676, Length=206, Percent_Identity=27.6699029126214, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71994604, Length=184, Percent_Identity=27.7173913043478, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17560220, Length=195, Percent_Identity=28.2051282051282, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17531453, Length=271, Percent_Identity=25.4612546125461, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI193210355, Length=202, Percent_Identity=27.2277227722772, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=185, Percent_Identity=32.972972972973, Blast_Score=91, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6322861, Length=196, Percent_Identity=33.6734693877551, Blast_Score=89, Evalue=8e-19,
Organism=Saccharomyces cerevisiae, GI6323882, Length=261, Percent_Identity=26.8199233716475, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24649181, Length=272, Percent_Identity=26.8382352941176, Blast_Score=88, Evalue=6e-18,
Organism=Drosophila melanogaster, GI23397609, Length=191, Percent_Identity=32.9842931937173, Blast_Score=88, Evalue=6e-18,
Organism=Drosophila melanogaster, GI17737361, Length=206, Percent_Identity=30.0970873786408, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI21357041, Length=190, Percent_Identity=28.9473684210526, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24639444, Length=207, Percent_Identity=28.0193236714976, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24644339, Length=180, Percent_Identity=31.1111111111111, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21355631, Length=244, Percent_Identity=25, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28571526, Length=199, Percent_Identity=30.1507537688442, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI18859837, Length=197, Percent_Identity=26.3959390862944, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI21358495, Length=251, Percent_Identity=23.1075697211155, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24643142, Length=226, Percent_Identity=25.6637168141593, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 30507; Mature: 30376

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKYKLKDKVVVITGSTGGLGLAIAQALQAKGAKLALLDLDLNKVESQAKQLGGQSIAAG
CCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHCCCCHHHHH
WVADVRSLESLEMAMANAAQHFGKIDVVIANAGIATTEALEHMAPETFERTIDINLTGVF
HHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCHHHHHEEEEEEHHHH
RTFRAAIPYVKQTQGYLLAVSSMAAFVHSPLNTHYTSSKAGVWALCDSLRLELKYLNIGV
HHHHHHCCHHHCCCCCEEHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHEEEEEEEECC
GSLHPTFFKTPMMDSIQNDPAGKAVWKGNSGIWKYISIEEVISGVVESIERRKDMTVVPK
CCCCCHHHCCCCHHHHCCCCCCCEEEECCCCCEEEEEHHHHHHHHHHHHHHHCCCEEECC
INTPIAKAPALFRNVIEFLGFNRKQLKQTMLLAEKNHNSF
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SKYKLKDKVVVITGSTGGLGLAIAQALQAKGAKLALLDLDLNKVESQAKQLGGQSIAAG
CCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHCCCCHHHHH
WVADVRSLESLEMAMANAAQHFGKIDVVIANAGIATTEALEHMAPETFERTIDINLTGVF
HHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCHHHHHEEEEEEHHHH
RTFRAAIPYVKQTQGYLLAVSSMAAFVHSPLNTHYTSSKAGVWALCDSLRLELKYLNIGV
HHHHHHCCHHHCCCCCEEHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHEEEEEEEECC
GSLHPTFFKTPMMDSIQNDPAGKAVWKGNSGIWKYISIEEVISGVVESIERRKDMTVVPK
CCCCCHHHCCCCHHHHCCCCCCCEEEECCCCCEEEEEHHHHHHHHHHHHHHHCCCEEECC
INTPIAKAPALFRNVIEFLGFNRKQLKQTMLLAEKNHNSF
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10473585 [H]