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The map label for this gene is adeS [H]

Identifier: 213157395

GI number: 213157395

Start: 2164473

End: 2165558

Strand: Direct

Name: adeS [H]

Synonym: AB57_2084

Alternate gene names: 213157395

Gene position: 2164473-2165558 (Clockwise)

Preceding gene: 213157394

Following gene: 213157399

Centisome position: 53.44

GC content: 37.57

Gene sequence:

>1086_bases
ATGAAAAGTAAGTTAGGAATTAGTAAGCAACTTTTTATTGCCTTAACTATTGTGAATTTAAGCGTTACGCTATTTTCTAT
AGTATTGGGTTATATCATTTATAACTATGCGATTGAAAAAGGCTGGATTAGCTTAAGCTCATTTCAACAAGAAGATTGGA
CCAGTTTTCATTTTGTAGACTGGATCTGGTTAGCCACTGTTATCTTCTGTGGCTGTATTATTTCATTAGTGATTGGCATG
CGCCTCGCAAAGCGTTTTATTGTGCCAATTAACTTCTTAGTCGAAGCAGCAAAAAAAATTAGTCACGGCGACCTCTCTGC
TAGAGCTTACGATAATAGAATTCACTCCGCCGAAATGTCGGAGCTTTTATATAATTTTAATGATATGGCTCAAAAGCTAG
AGGTTTCCGTCAAAAATGCGCAGGTTTGGAATGCAGCTATCGCACATGAGTTAAGAACGCCTATAACGATATTACAAGGT
CGTTTACAGGGAATTATTGATGGCGTTTTTAAACCTGATGAAGTCCTATTTAAAAGCCTTTTAAATCAAGTTGAAGGTTT
ATCTCACTTAGTCGAAGACTTACGGACTTTAAGCTTAGTAGAGAACCAGCAACTCCGGTTAAATTATGAATTGTTTGACT
TGAAGGCGGTAGTTGAAAAAGTTCTTAAAGCATTTGAAGATCGTTTGGATCAAGCTAAGCTAGTACCAGAACTTGACCTA
ACGTCCACTCCTGTATATTGCGACCGCCGTCGTATTGAGCAAGTTTTAATTGCTTTAATTGATAATGCGATTCGCTATTC
AAATGCAGGCAAACTTAAAATCTCTTCAGAAGTGGTTGCAGACAACTGGATATTAAAAATTGAGGATGAAGGCCCCGGCA
TTGCAACCGAGTTTCGGGACGATTTATTTAAGCCTTTCTTTAGATTAGAAGAATCAAGGAATAAAGAATTTGGCGGCACA
GGTTTAGGTCTTGCTGTTGTACATGCAATTATTGTGGCACTGAAAGGCACTATTCAATATAGCAATCAAGGCTCGAAAAG
TGTTTTCACCATAAAAATTTCTATGGGTCATGAAGAGATGGGGTAA

Upstream 100 bases:

>100_bases
ATGTTAATTAATGTGCGTGGCGTGGGATATAGACTAGATAATCCCCTAGCTGTAAAAGATGATGCCTAAATAATATTAAA
AAATAGCTAGGGAATATTTT

Downstream 100 bases:

>100_bases
TTCGCTAAATTAAAAAATCTTAGAGTTAAAGTGCCCCCTCACTCTCTTTTATTCTTCTACGAATTTCTTCTCGCCATTTT
GTGGCATTTTCCTGTTGTTT

Product: AdeS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 361; Mature: 361

Protein sequence:

>361_residues
MKSKLGISKQLFIALTIVNLSVTLFSIVLGYIIYNYAIEKGWISLSSFQQEDWTSFHFVDWIWLATVIFCGCIISLVIGM
RLAKRFIVPINFLVEAAKKISHGDLSARAYDNRIHSAEMSELLYNFNDMAQKLEVSVKNAQVWNAAIAHELRTPITILQG
RLQGIIDGVFKPDEVLFKSLLNQVEGLSHLVEDLRTLSLVENQQLRLNYELFDLKAVVEKVLKAFEDRLDQAKLVPELDL
TSTPVYCDRRRIEQVLIALIDNAIRYSNAGKLKISSEVVADNWILKIEDEGPGIATEFRDDLFKPFFRLEESRNKEFGGT
GLGLAVVHAIIVALKGTIQYSNQGSKSVFTIKISMGHEEMG

Sequences:

>Translated_361_residues
MKSKLGISKQLFIALTIVNLSVTLFSIVLGYIIYNYAIEKGWISLSSFQQEDWTSFHFVDWIWLATVIFCGCIISLVIGM
RLAKRFIVPINFLVEAAKKISHGDLSARAYDNRIHSAEMSELLYNFNDMAQKLEVSVKNAQVWNAAIAHELRTPITILQG
RLQGIIDGVFKPDEVLFKSLLNQVEGLSHLVEDLRTLSLVENQQLRLNYELFDLKAVVEKVLKAFEDRLDQAKLVPELDL
TSTPVYCDRRRIEQVLIALIDNAIRYSNAGKLKISSEVVADNWILKIEDEGPGIATEFRDDLFKPFFRLEESRNKEFGGT
GLGLAVVHAIIVALKGTIQYSNQGSKSVFTIKISMGHEEMG
>Mature_361_residues
MKSKLGISKQLFIALTIVNLSVTLFSIVLGYIIYNYAIEKGWISLSSFQQEDWTSFHFVDWIWLATVIFCGCIISLVIGM
RLAKRFIVPINFLVEAAKKISHGDLSARAYDNRIHSAEMSELLYNFNDMAQKLEVSVKNAQVWNAAIAHELRTPITILQG
RLQGIIDGVFKPDEVLFKSLLNQVEGLSHLVEDLRTLSLVENQQLRLNYELFDLKAVVEKVLKAFEDRLDQAKLVPELDL
TSTPVYCDRRRIEQVLIALIDNAIRYSNAGKLKISSEVVADNWILKIEDEGPGIATEFRDDLFKPFFRLEESRNKEFGGT
GLGLAVVHAIIVALKGTIQYSNQGSKSVFTIKISMGHEEMG

Specific function: Member of the two-component regulatory system BaeS/BaeR. May activate BaeR by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=257, Percent_Identity=34.2412451361868, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1787894, Length=246, Percent_Identity=31.3008130081301, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1786783, Length=280, Percent_Identity=28.5714285714286, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1790346, Length=278, Percent_Identity=29.4964028776978, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1789808, Length=325, Percent_Identity=27.6923076923077, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1788549, Length=256, Percent_Identity=29.296875, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI145693157, Length=245, Percent_Identity=26.1224489795918, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI87081816, Length=250, Percent_Identity=24, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1789149, Length=358, Percent_Identity=24.5810055865922, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1786600, Length=234, Percent_Identity=28.2051282051282, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI1790551, Length=290, Percent_Identity=28.6206896551724, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1786912, Length=221, Percent_Identity=29.8642533936652, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790861, Length=234, Percent_Identity=27.7777777777778, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790436, Length=213, Percent_Identity=28.169014084507, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI48994928, Length=230, Percent_Identity=26.5217391304348, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1788279, Length=295, Percent_Identity=25.4237288135593, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788713, Length=226, Percent_Identity=26.5486725663717, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790300, Length=224, Percent_Identity=25.4464285714286, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 40772; Mature: 40772

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSKLGISKQLFIALTIVNLSVTLFSIVLGYIIYNYAIEKGWISLSSFQQEDWTSFHFVD
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEHHHCCCCCCCHHHHHH
WIWLATVIFCGCIISLVIGMRLAKRFIVPINFLVEAAKKISHGDLSARAYDNRIHSAEMS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
ELLYNFNDMAQKLEVSVKNAQVWNAAIAHELRTPITILQGRLQGIIDGVFKPDEVLFKSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCHHHHHHHH
LNQVEGLSHLVEDLRTLSLVENQQLRLNYELFDLKAVVEKVLKAFEDRLDQAKLVPELDL
HHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
TSTPVYCDRRRIEQVLIALIDNAIRYSNAGKLKISSEVVADNWILKIEDEGPGIATEFRD
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCEEECCCEEEEECCCCCCHHHHHH
DLFKPFFRLEESRNKEFGGTGLGLAVVHAIIVALKGTIQYSNQGSKSVFTIKISMGHEEM
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHEEECCCCCCEEEEEEEECCCCCC
G
C
>Mature Secondary Structure
MKSKLGISKQLFIALTIVNLSVTLFSIVLGYIIYNYAIEKGWISLSSFQQEDWTSFHFVD
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEHHHCCCCCCCHHHHHH
WIWLATVIFCGCIISLVIGMRLAKRFIVPINFLVEAAKKISHGDLSARAYDNRIHSAEMS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
ELLYNFNDMAQKLEVSVKNAQVWNAAIAHELRTPITILQGRLQGIIDGVFKPDEVLFKSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCHHHHHHHH
LNQVEGLSHLVEDLRTLSLVENQQLRLNYELFDLKAVVEKVLKAFEDRLDQAKLVPELDL
HHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
TSTPVYCDRRRIEQVLIALIDNAIRYSNAGKLKISSEVVADNWILKIEDEGPGIATEFRD
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCEEECCCEEEEECCCCCCHHHHHH
DLFKPFFRLEESRNKEFGGTGLGLAVVHAIIVALKGTIQYSNQGSKSVFTIKISMGHEEM
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHEEECCCCCCEEEEEEEECCCCCC
G
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8282725; 9097040; 9278503 [H]