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The map label for this gene is 213157304

Identifier: 213157304

GI number: 213157304

Start: 2084011

End: 2085087

Strand: Direct

Name: 213157304

Synonym: AB57_1993

Alternate gene names: NA

Gene position: 2084011-2085087 (Clockwise)

Preceding gene: 213157303

Following gene: 213157305

Centisome position: 51.45

GC content: 38.72

Gene sequence:

>1077_bases
ATGATTAGCTATAAGAAAACCGATATGAACCATGGCACATTTCCTGTTTTTGATGGCCATAATGATGTACTAACCCGATT
GTGGTTAAGTGATCATAACAATCCTGCTCAAGCTTTTATTCAAGAAGGTTTAGCCGGACATCTCGATTTAAAACGTTGCC
AACAAGCCGGTTTTGTTGGCGGTATGTTTGCTATTTTCTTGCCGCCTTTTCATTATGTTAAGCAGCATCATCCCAACAAA
CTATTTGACCAAGACGCATCTGACTTCACGCAACAGCAAATTGAACACATTTGTTTGGCACAACTTGATTTAGCAAAACA
ACTTGCCGAGTACTCTAACGACATTCAAATTTGCACAACTGTTCAGGATATCCAGCACTGCCTAACACAGCAAAAGTTAG
CCATTGTATTGCATATGGAAGGTGCTGAAGCATTACAACATAATCCAGATTTACTCGATGTATTTTATGATGCCGGGCTT
CGTAGCATCGGTCCACTTTGGAATAGACCAAGTCGTTTTGGACATGGTTTAAATGTCAAGTTTCCGCATTCACCTGATAC
TGGAGCAGGTCTTACAAACGAAGGTAAAGCTTTTATAAAGCGCTGTGCTGATAAAAAAATGGTGATTGATGTTTCCCATA
TGAATGAACGAGCTTTTTGGGATACAACTAACATTCTTCAGCAGCCAATTGTCGCAACTCACTCAAATGTTCATGCTTTA
TGTCCACAAGCCAGAAACTTAACAGATAACCAACTTAAAGCAATTAAGGACTCTAAAGGCATAGTCGGGTTAAATTTTGA
TGTCGCATTTTTGCGTAAAGACGGGCAGCGTGATGCAAACACATCCATTGAGGTACTTTTAGAACATCTTGAATATTTAA
TAGATCAAATGGGAGAAAATCATGTCGGTTTTGGTTCTGACTTTGATGGAGCACTGATTAGTCATGAAATTGAAGATGTA
AGGGGACTACACCTACTGATTGAAGCAATGCAAAAGCGACATTATTCGAATGAGATTATAGAAAAAATTTGTTTTTCTAA
CTGGCTAACCGTGCTCAATCGCATCCTAAGTAAATAA

Upstream 100 bases:

>100_bases
AGCGAAATTGATTCCTCTCTGGAAAAATTGGTGTTCCGTAATAGCCGAAATTCAAAGCAATTTACGGTTCAACAAAACAT
TCCGGTTCAAAATATTGTAG

Downstream 100 bases:

>100_bases
TTTATTGCTAAATATATTAAAAATAGCGAATTATTTTACATTTTTTATTGGCCGAAATGACTAAAAAAAGTACAACTAGT
TTAATTGTCAACCAATTGCT

Product: dipeptidase

Products: NA

Alternate protein names: ORF R [H]

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MISYKKTDMNHGTFPVFDGHNDVLTRLWLSDHNNPAQAFIQEGLAGHLDLKRCQQAGFVGGMFAIFLPPFHYVKQHHPNK
LFDQDASDFTQQQIEHICLAQLDLAKQLAEYSNDIQICTTVQDIQHCLTQQKLAIVLHMEGAEALQHNPDLLDVFYDAGL
RSIGPLWNRPSRFGHGLNVKFPHSPDTGAGLTNEGKAFIKRCADKKMVIDVSHMNERAFWDTTNILQQPIVATHSNVHAL
CPQARNLTDNQLKAIKDSKGIVGLNFDVAFLRKDGQRDANTSIEVLLEHLEYLIDQMGENHVGFGSDFDGALISHEIEDV
RGLHLLIEAMQKRHYSNEIIEKICFSNWLTVLNRILSK

Sequences:

>Translated_358_residues
MISYKKTDMNHGTFPVFDGHNDVLTRLWLSDHNNPAQAFIQEGLAGHLDLKRCQQAGFVGGMFAIFLPPFHYVKQHHPNK
LFDQDASDFTQQQIEHICLAQLDLAKQLAEYSNDIQICTTVQDIQHCLTQQKLAIVLHMEGAEALQHNPDLLDVFYDAGL
RSIGPLWNRPSRFGHGLNVKFPHSPDTGAGLTNEGKAFIKRCADKKMVIDVSHMNERAFWDTTNILQQPIVATHSNVHAL
CPQARNLTDNQLKAIKDSKGIVGLNFDVAFLRKDGQRDANTSIEVLLEHLEYLIDQMGENHVGFGSDFDGALISHEIEDV
RGLHLLIEAMQKRHYSNEIIEKICFSNWLTVLNRILSK
>Mature_358_residues
MISYKKTDMNHGTFPVFDGHNDVLTRLWLSDHNNPAQAFIQEGLAGHLDLKRCQQAGFVGGMFAIFLPPFHYVKQHHPNK
LFDQDASDFTQQQIEHICLAQLDLAKQLAEYSNDIQICTTVQDIQHCLTQQKLAIVLHMEGAEALQHNPDLLDVFYDAGL
RSIGPLWNRPSRFGHGLNVKFPHSPDTGAGLTNEGKAFIKRCADKKMVIDVSHMNERAFWDTTNILQQPIVATHSNVHAL
CPQARNLTDNQLKAIKDSKGIVGLNFDVAFLRKDGQRDANTSIEVLLEHLEYLIDQMGENHVGFGSDFDGALISHEIEDV
RGLHLLIEAMQKRHYSNEIIEKICFSNWLTVLNRILSK

Specific function: Unknown

COG id: COG2355

COG function: function code E; Zn-dependent dipeptidase, microsomal dipeptidase homolog

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M19 family [H]

Homologues:

Organism=Homo sapiens, GI11641269, Length=351, Percent_Identity=23.6467236467236, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI193211608, Length=346, Percent_Identity=23.4104046242775, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI189458885, Length=347, Percent_Identity=23.0547550432277, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI4758190, Length=347, Percent_Identity=23.0547550432277, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI193211610, Length=346, Percent_Identity=23.4104046242775, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI221475880, Length=353, Percent_Identity=24.6458923512748, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI281362638, Length=354, Percent_Identity=25.4237288135593, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI281362636, Length=354, Percent_Identity=25.4237288135593, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI161083233, Length=265, Percent_Identity=25.6603773584906, Blast_Score=99, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000180
- InterPro:   IPR008257 [H]

Pfam domain/function: PF01244 Peptidase_M19 [H]

EC number: NA

Molecular weight: Translated: 40492; Mature: 40492

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: PS00869 RENAL_DIPEPTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISYKKTDMNHGTFPVFDGHNDVLTRLWLSDHNNPAQAFIQEGLAGHLDLKRCQQAGFVG
CCCCCCCCCCCCCCEEECCCHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHCCCHH
GMFAIFLPPFHYVKQHHPNKLFDQDASDFTQQQIEHICLAQLDLAKQLAEYSNDIQICTT
HHHHHHHCCHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHH
VQDIQHCLTQQKLAIVLHMEGAEALQHNPDLLDVFYDAGLRSIGPLWNRPSRFGHGLNVK
HHHHHHHHHHHHEEEEEEECCHHHHHCCCCHHHHHHHHCHHHHCCCCCCCHHHCCCCCEE
FPHSPDTGAGLTNEGKAFIKRCADKKMVIDVSHMNERAFWDTTNILQQPIVATHSNVHAL
CCCCCCCCCCCCCCHHHHHHHHCCCCEEEEECCCCCCHHCCHHHHHHCCHHHCCCCHHHH
CPQARNLTDNQLKAIKDSKGIVGLNFDVAFLRKDGQRDANTSIEVLLEHLEYLIDQMGEN
CCCCCCCCHHHHHHHHCCCCEEEECCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCC
HVGFGSDFDGALISHEIEDVRGLHLLIEAMQKRHYSNEIIEKICFSNWLTVLNRILSK
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MISYKKTDMNHGTFPVFDGHNDVLTRLWLSDHNNPAQAFIQEGLAGHLDLKRCQQAGFVG
CCCCCCCCCCCCCCEEECCCHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHCCCHH
GMFAIFLPPFHYVKQHHPNKLFDQDASDFTQQQIEHICLAQLDLAKQLAEYSNDIQICTT
HHHHHHHCCHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHH
VQDIQHCLTQQKLAIVLHMEGAEALQHNPDLLDVFYDAGLRSIGPLWNRPSRFGHGLNVK
HHHHHHHHHHHHEEEEEEECCHHHHHCCCCHHHHHHHHCHHHHCCCCCCCHHHCCCCCEE
FPHSPDTGAGLTNEGKAFIKRCADKKMVIDVSHMNERAFWDTTNILQQPIVATHSNVHAL
CCCCCCCCCCCCCCHHHHHHHHCCCCEEEEECCCCCCHHCCHHHHHHCCHHHCCCCHHHH
CPQARNLTDNQLKAIKDSKGIVGLNFDVAFLRKDGQRDANTSIEVLLEHLEYLIDQMGEN
CCCCCCCCHHHHHHHHCCCCEEEECCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCC
HVGFGSDFDGALISHEIEDVRGLHLLIEAMQKRHYSNEIIEKICFSNWLTVLNRILSK
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2536663 [H]