Click here to switch to the map view.

The map label for this gene is aroC [H]

Identifier: 213157236

GI number: 213157236

Start: 2008305

End: 2009396

Strand: Direct

Name: aroC [H]

Synonym: AB57_1923

Alternate gene names: 213157236

Gene position: 2008305-2009396 (Clockwise)

Preceding gene: 213157235

Following gene: 213157238

Centisome position: 49.58

GC content: 43.22

Gene sequence:

>1092_bases
ATGGCAGGGAACAGTATTGGACAACTCTTTCGTGTGACTACATGCGGTGAATCGCATGGGGTTGGTTTAATGGCAATTGT
TGATGGAGTGCCACCAGGCCTTGCATTAACCGAAGAAGATTTGCAAAAAGATCTGGATCGCCGTAAGCCGGGAACCTCGA
AATTTGCGACTCAGCGTAAAGAGCCTGATCAGGTTGAAATCATTTCTGGTGTGTTTGAGGGTAAAACTACTGGTACGCCA
ATTGGTTTACTCATTCGCAATACAGACCAAAAATCGAAAGATTATGGAAATATTGCACAAACTTTTAGACCGGGTCACGC
AGATTACACTTATACGCAAAAGTATGGTTTCCGCGACTATCGTGGTGGTGGCCGTTCAAGTGCTCGTGAAACTGCTATGC
GTGTTGCAGCTGGTGCTATTGCGAAGAAATATTTAGCAGAAAAATTTGGTGTTCTGATCCGCGGTCATGTGACTCAAATT
GGTAATGAAGTTGCTGAAAAACTAGATTGGAATGAAGTTCCAAATAATCCATTTTTCTGTGGCGATGTAGATGCTGTTCC
TCGTTTTGAAGCATTGGTTACGTCTTTACGTGAACAAGGTACAAGTTGTGGTGCTAAGTTAGAAATTTTAGCCGAAAAAG
TTCCTGTAGGTTGGGGTGAGCCTGTCTTTGATCGTTTAGATGCTGATATTGCACATGCAATGATGAGTATCAATGCGGTT
AAAGGTGTTGAAATTGGTGATGGTTTTGCTGTAGCAGGACAGTTTGGACATGAAACACGTGACGAATTGACTAGTCATGG
TTTTCTAGCAAATCATGCTGGTGGTATTTTAGGTGGTATTTCAAGTGGCCAGACCATTCGTGTGGCGATTGCACTAAAAC
CAACAGCAAGTATTACTACTCCGGGTAAAACGATTAATTTAAATCGTGAAGATACTGATGTGTTAACTAAAGGCCGTCAT
GACCCGTGTGTGGGCGTTCGAGCAACTCCGATTGCAGAAGCAATGTTAGCGATAGTTCTAATGGATCATTTCTTACGCCA
CCGTGCTCAAAACGCGGATGTTGTTCCTCCATTTGCGCCAATCGAACCATAG

Upstream 100 bases:

>100_bases
TACTTTCCAAAAAGGTGGTTCAGGTATTTTTGCTTTGACTGCTGAACAATGTCGTCGTTATAGAAAATTATTTGAAGAAC
AAGTTTAAGGAGTTGGACAT

Downstream 100 bases:

>100_bases
TTAGTTCTAATCAGCGTATTTAAAAAGCCACATAAACAAAATTATGTGGCTTTTCTATTTTTATTGAAATCACATGATTA
CCTTAAAAATAAATCATTAA

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase [H]

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MAGNSIGQLFRVTTCGESHGVGLMAIVDGVPPGLALTEEDLQKDLDRRKPGTSKFATQRKEPDQVEIISGVFEGKTTGTP
IGLLIRNTDQKSKDYGNIAQTFRPGHADYTYTQKYGFRDYRGGGRSSARETAMRVAAGAIAKKYLAEKFGVLIRGHVTQI
GNEVAEKLDWNEVPNNPFFCGDVDAVPRFEALVTSLREQGTSCGAKLEILAEKVPVGWGEPVFDRLDADIAHAMMSINAV
KGVEIGDGFAVAGQFGHETRDELTSHGFLANHAGGILGGISSGQTIRVAIALKPTASITTPGKTINLNREDTDVLTKGRH
DPCVGVRATPIAEAMLAIVLMDHFLRHRAQNADVVPPFAPIEP

Sequences:

>Translated_363_residues
MAGNSIGQLFRVTTCGESHGVGLMAIVDGVPPGLALTEEDLQKDLDRRKPGTSKFATQRKEPDQVEIISGVFEGKTTGTP
IGLLIRNTDQKSKDYGNIAQTFRPGHADYTYTQKYGFRDYRGGGRSSARETAMRVAAGAIAKKYLAEKFGVLIRGHVTQI
GNEVAEKLDWNEVPNNPFFCGDVDAVPRFEALVTSLREQGTSCGAKLEILAEKVPVGWGEPVFDRLDADIAHAMMSINAV
KGVEIGDGFAVAGQFGHETRDELTSHGFLANHAGGILGGISSGQTIRVAIALKPTASITTPGKTINLNREDTDVLTKGRH
DPCVGVRATPIAEAMLAIVLMDHFLRHRAQNADVVPPFAPIEP
>Mature_362_residues
AGNSIGQLFRVTTCGESHGVGLMAIVDGVPPGLALTEEDLQKDLDRRKPGTSKFATQRKEPDQVEIISGVFEGKTTGTPI
GLLIRNTDQKSKDYGNIAQTFRPGHADYTYTQKYGFRDYRGGGRSSARETAMRVAAGAIAKKYLAEKFGVLIRGHVTQIG
NEVAEKLDWNEVPNNPFFCGDVDAVPRFEALVTSLREQGTSCGAKLEILAEKVPVGWGEPVFDRLDADIAHAMMSINAVK
GVEIGDGFAVAGQFGHETRDELTSHGFLANHAGGILGGISSGQTIRVAIALKPTASITTPGKTINLNREDTDVLTKGRHD
PCVGVRATPIAEAMLAIVLMDHFLRHRAQNADVVPPFAPIEP

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788669, Length=354, Percent_Identity=70.6214689265537, Blast_Score=492, Evalue=1e-140,
Organism=Saccharomyces cerevisiae, GI6321290, Length=368, Percent_Identity=42.9347826086957, Blast_Score=277, Evalue=2e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000453
- InterPro:   IPR020541 [H]

Pfam domain/function: PF01264 Chorismate_synt [H]

EC number: =4.2.3.5 [H]

Molecular weight: Translated: 39002; Mature: 38871

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS00788 CHORISMATE_SYNTHASE_2 ; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGNSIGQLFRVTTCGESHGVGLMAIVDGVPPGLALTEEDLQKDLDRRKPGTSKFATQRK
CCCCCHHHEEEEEECCCCCCCEEEEEECCCCCCCEECHHHHHHHHHHCCCCCHHHHHCCC
EPDQVEIISGVFEGKTTGTPIGLLIRNTDQKSKDYGNIAQTFRPGHADYTYTQKYGFRDY
CCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCEEHHCCCCCCC
RGGGRSSARETAMRVAAGAIAKKYLAEKFGVLIRGHVTQIGNEVAEKLDWNEVPNNPFFC
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEE
GDVDAVPRFEALVTSLREQGTSCGAKLEILAEKVPVGWGEPVFDRLDADIAHAMMSINAV
CCCCCCHHHHHHHHHHHHCCCCCCCHHEEHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
KGVEIGDGFAVAGQFGHETRDELTSHGFLANHAGGILGGISSGQTIRVAIALKPTASITT
CCEECCCCEEEECCCCCHHHHHHHHCCCHHHCCCCCEECCCCCCEEEEEEEECCCCCCCC
PGKTINLNREDTDVLTKGRHDPCVGVRATPIAEAMLAIVLMDHFLRHRAQNADVVPPFAP
CCCEEECCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
IEP
CCC
>Mature Secondary Structure 
AGNSIGQLFRVTTCGESHGVGLMAIVDGVPPGLALTEEDLQKDLDRRKPGTSKFATQRK
CCCCHHHEEEEEECCCCCCCEEEEEECCCCCCCEECHHHHHHHHHHCCCCCHHHHHCCC
EPDQVEIISGVFEGKTTGTPIGLLIRNTDQKSKDYGNIAQTFRPGHADYTYTQKYGFRDY
CCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCEEHHCCCCCCC
RGGGRSSARETAMRVAAGAIAKKYLAEKFGVLIRGHVTQIGNEVAEKLDWNEVPNNPFFC
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEE
GDVDAVPRFEALVTSLREQGTSCGAKLEILAEKVPVGWGEPVFDRLDADIAHAMMSINAV
CCCCCCHHHHHHHHHHHHCCCCCCCHHEEHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
KGVEIGDGFAVAGQFGHETRDELTSHGFLANHAGGILGGISSGQTIRVAIALKPTASITT
CCEECCCCEEEECCCCCHHHHHHHHCCCHHHCCCCCEECCCCCCEEEEEEEECCCCCCCC
PGKTINLNREDTDVLTKGRHDPCVGVRATPIAEAMLAIVLMDHFLRHRAQNADVVPPFAP
CCCEEECCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
IEP
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA