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The map label for this gene is trpB [H]

Identifier: 213157234

GI number: 213157234

Start: 2005846

End: 2007051

Strand: Direct

Name: trpB [H]

Synonym: AB57_1921

Alternate gene names: 213157234

Gene position: 2005846-2007051 (Clockwise)

Preceding gene: 213157233

Following gene: 213157235

Centisome position: 49.52

GC content: 40.13

Gene sequence:

>1206_bases
ATGCAACATCAAATTAATGGTATTGCTTTACCGAATGAACAAGGATTTTTTGGTGAATATGGAGGGCAATTTATTCCTCC
ACATTTAAAAGAAGCAATGGATGAAATTAATGTTGCTTATGAAGAAATTCGCCATACACCAGAATTTCAAAATGAATTAG
CAGACCTCTTTGCAAATTATGTCGGCCGTCCAAGTCCTTTATTTCATGCAAAACGCCTTTCAGAACAGTTAGGTGGCGCG
CAAATTTATTTAAAGCGTGAAGACTTAAATCATACCGGTGCCCACAAAATTAATCACTGTTTAGGTGAGGCTCTACTTGC
CAAATATATGGGCAAAAAGAAAGTCATTGCCGAGACTGGTGCGGGACAGCATGGCGTTGCTTTAGCAACGGCTTGTGCTT
TAGTTGGTATTCCATGTGAAATTCACATGGGTCAAGTAGATATTGAAAAAGAACACCCTAATGTGGTCAAAATGAAAATT
TTGGGTGCTCATTTAGTTTCAGTAACACGTGGTACAGCAACCTTAAAAGATGCAGTGGATAGCGCTTTTGAAGAATATTT
AAAAGACCCTAAAAACTTTATTTATGCAATTGGTTCTGTGGTTGGACCACATCCATTTCCAAAAATGGTTCGAGATTTTC
AATCGATTATTGGTAATGAAATTAAAGAGCAGACGCATCATCGTTTTGGTAAAAACCCAGATTATGTTGTCGCATGTGTT
GGTGGCGGTTCAAATGCAATCGGTGCCTTTACAGCATTTCTAAATGATTCGGATGTGAAATTGGTTGGGGTTGAACCAGC
AGGACATGGTTTAGAAACTCACATGCATTCGGCAACTTTAACCTTAGGTAAACCAAGTCAAATTCATGGTATGGCGTGTT
ACGTGCTTGAAAATGAAGCTGGTGAACCGTTACCCGTGCATTCTATTGCTTCAGGATTGGACTATCCTGGTGTTGGGCCA
CAGCATAGTTTCTTAAAAGATTTAGGCCGTGTGGAATATAGCACTGCAACTGACCAAGAATGTTTGGATGCTTTTATGAC
CTTATCTCGTGTAGAAGGAATTGTTCCTGCGCTTGAAAGCTCACATGCTGTCGCATGGGCAATACGTGAAGCGTCAAAGC
TGCCGAAAGAAACCATGATCGTGGTGAATCTATCGGGTCGTGGCGATAAAGATTCTGATTATGTGGCAGAAAAACTTAAG
CTTTAA

Upstream 100 bases:

>100_bases
AAACCACATGTATCCAATGACTCTAAAAGGCATTGAGGACTTAACGCGTTACCTTTCTCGATAAACTTGATAACTTTAAT
AATTTAAAAAGAGGGATAAT

Downstream 100 bases:

>100_bases
ACTAAATATACTTAAAGAGCGGCCCATTTCGAAAGGCCGCTTTTTTATTTTATAGACTAAATTTTACCCTACTTAAAAGT
TCATTATTTCTTAATTAAAA

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MQHQINGIALPNEQGFFGEYGGQFIPPHLKEAMDEINVAYEEIRHTPEFQNELADLFANYVGRPSPLFHAKRLSEQLGGA
QIYLKREDLNHTGAHKINHCLGEALLAKYMGKKKVIAETGAGQHGVALATACALVGIPCEIHMGQVDIEKEHPNVVKMKI
LGAHLVSVTRGTATLKDAVDSAFEEYLKDPKNFIYAIGSVVGPHPFPKMVRDFQSIIGNEIKEQTHHRFGKNPDYVVACV
GGGSNAIGAFTAFLNDSDVKLVGVEPAGHGLETHMHSATLTLGKPSQIHGMACYVLENEAGEPLPVHSIASGLDYPGVGP
QHSFLKDLGRVEYSTATDQECLDAFMTLSRVEGIVPALESSHAVAWAIREASKLPKETMIVVNLSGRGDKDSDYVAEKLK
L

Sequences:

>Translated_401_residues
MQHQINGIALPNEQGFFGEYGGQFIPPHLKEAMDEINVAYEEIRHTPEFQNELADLFANYVGRPSPLFHAKRLSEQLGGA
QIYLKREDLNHTGAHKINHCLGEALLAKYMGKKKVIAETGAGQHGVALATACALVGIPCEIHMGQVDIEKEHPNVVKMKI
LGAHLVSVTRGTATLKDAVDSAFEEYLKDPKNFIYAIGSVVGPHPFPKMVRDFQSIIGNEIKEQTHHRFGKNPDYVVACV
GGGSNAIGAFTAFLNDSDVKLVGVEPAGHGLETHMHSATLTLGKPSQIHGMACYVLENEAGEPLPVHSIASGLDYPGVGP
QHSFLKDLGRVEYSTATDQECLDAFMTLSRVEGIVPALESSHAVAWAIREASKLPKETMIVVNLSGRGDKDSDYVAEKLK
L
>Mature_401_residues
MQHQINGIALPNEQGFFGEYGGQFIPPHLKEAMDEINVAYEEIRHTPEFQNELADLFANYVGRPSPLFHAKRLSEQLGGA
QIYLKREDLNHTGAHKINHCLGEALLAKYMGKKKVIAETGAGQHGVALATACALVGIPCEIHMGQVDIEKEHPNVVKMKI
LGAHLVSVTRGTATLKDAVDSAFEEYLKDPKNFIYAIGSVVGPHPFPKMVRDFQSIIGNEIKEQTHHRFGKNPDYVVACV
GGGSNAIGAFTAFLNDSDVKLVGVEPAGHGLETHMHSATLTLGKPSQIHGMACYVLENEAGEPLPVHSIASGLDYPGVGP
QHSFLKDLGRVEYSTATDQECLDAFMTLSRVEGIVPALESSHAVAWAIREASKLPKETMIVVNLSGRGDKDSDYVAEKLK
L

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=386, Percent_Identity=48.9637305699482, Blast_Score=379, Evalue=1e-106,
Organism=Saccharomyces cerevisiae, GI6321412, Length=384, Percent_Identity=51.3020833333333, Blast_Score=404, Evalue=1e-113,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 43545; Mature: 43545

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQHQINGIALPNEQGFFGEYGGQFIPPHLKEAMDEINVAYEEIRHTPEFQNELADLFANY
CCCCCCCEECCCCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
VGRPSPLFHAKRLSEQLGGAQIYLKREDLNHTGAHKINHCLGEALLAKYMGKKKVIAETG
CCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECC
AGQHGVALATACALVGIPCEIHMGQVDIEKEHPNVVKMKILGAHLVSVTRGTATLKDAVD
CCCCHHHHHHHHHHHCCCCEEECCCEEEECCCCCEEEEEEHHHHHHHHHCCCHHHHHHHH
SAFEEYLKDPKNFIYAIGSVVGPHPFPKMVRDFQSIIGNEIKEQTHHRFGKNPDYVVACV
HHHHHHHHCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
GGGSNAIGAFTAFLNDSDVKLVGVEPAGHGLETHMHSATLTLGKPSQIHGMACYVLENEA
CCCCCHHHHHHHEECCCCEEEEEECCCCCCHHHHHCCEEEECCCCCCCCCEEEEEEECCC
GEPLPVHSIASGLDYPGVGPQHSFLKDLGRVEYSTATDQECLDAFMTLSRVEGIVPALES
CCCCCHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
SHAVAWAIREASKLPKETMIVVNLSGRGDKDSDYVAEKLKL
CCHHHHHHHHHHHCCCEEEEEEEECCCCCCCHHHHHHHHCC
>Mature Secondary Structure
MQHQINGIALPNEQGFFGEYGGQFIPPHLKEAMDEINVAYEEIRHTPEFQNELADLFANY
CCCCCCCEECCCCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
VGRPSPLFHAKRLSEQLGGAQIYLKREDLNHTGAHKINHCLGEALLAKYMGKKKVIAETG
CCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECC
AGQHGVALATACALVGIPCEIHMGQVDIEKEHPNVVKMKILGAHLVSVTRGTATLKDAVD
CCCCHHHHHHHHHHHCCCCEEECCCEEEECCCCCEEEEEEHHHHHHHHHCCCHHHHHHHH
SAFEEYLKDPKNFIYAIGSVVGPHPFPKMVRDFQSIIGNEIKEQTHHRFGKNPDYVVACV
HHHHHHHHCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
GGGSNAIGAFTAFLNDSDVKLVGVEPAGHGLETHMHSATLTLGKPSQIHGMACYVLENEA
CCCCCHHHHHHHEECCCCEEEEEECCCCCCHHHHHCCEEEECCCCCCCCCEEEEEEECCC
GEPLPVHSIASGLDYPGVGPQHSFLKDLGRVEYSTATDQECLDAFMTLSRVEGIVPALES
CCCCCHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
SHAVAWAIREASKLPKETMIVVNLSGRGDKDSDYVAEKLKL
CCHHHHHHHHHHHCCCEEEEEEEECCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]