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The map label for this gene is cysQ [H]

Identifier: 213157157

GI number: 213157157

Start: 1928009

End: 1928866

Strand: Direct

Name: cysQ [H]

Synonym: AB57_1840

Alternate gene names: 213157157

Gene position: 1928009-1928866 (Clockwise)

Preceding gene: 213157155

Following gene: 213157158

Centisome position: 47.6

GC content: 36.25

Gene sequence:

>858_bases
ATGTTTATAACAACAACTTGCCCCAATGATGCTTTAATTGAACAGCTACTACCAATCTTGGAAGAAGCTAGCCAAATCTT
ATTACAAGAATATCAAAATTATTCGGCTGGATATGAATTTACGATTGAAGAAAAACATGATGATTCACCTGTAACGCAAG
CAGATTTAAAGGTAAATCGTTTTTTATTAAAGCATCTTGCAGAAATTACACCTGAGTTACCAGTTTTATCGGAAGAAAGT
GACTATAGTGCTCGCCATGCTTGGTCTTCTTGCTGGATGCTAGATCCACTTGATGGTACGAAAGAGTTTATACATGAGCG
AGATGAGTTCACGATAAACTTGAGTTTGATTGAAGGGCGTGAAACGATTTTTTCGGTGATTGTTGTGCCATGTGAACAGG
TCGTTTATTTAGGTTATTTAAAGGATTTACCCTTTAAATATAGCTTTAGCCAACAACAATGGTATCAATATCAAAAAACA
CCTTATTCAAAACAAGCTCCTGTACAAATTGGTTTAAGTCATAGTAGTAAAAATCCGAAATATCAGAAATTCATTGAACC
TATTGAAAAGATTCGTACCGTAATTCGTCGTGAAGCGGGTAGCGCTTATAAGTTTTGTATGATGTTAGAAGGCGAGATCG
ATATTTATCCTAGATTTCATCCGACATCAGAATGGGATACCAGCTCAGGTCAAGGATTATTAGAAAGTATAGGTGGAGGT
TTACTCACTCTAACAGGTAAGCCCTTTGAATATAACCAACGTGATACCGTATTAAATGGGGGCTTTATCGCATTTCGTGA
TCAGGAAAGCAAAAAAATAGCATTTGAAGCTTTAGCTCAATCAGGTGTTTTGGATTGA

Upstream 100 bases:

>100_bases
TAAAAAGTTAAGTCTTTTTGTAAGGATACTAGACTGTTGGTGAATATTGAATTTGTCATAATTCACTTATAATGAAAAGG
AAAGTAAATAGAGCTTATTT

Downstream 100 bases:

>100_bases
GAGTTATTGTAGACATGCTATAGTGGCAAAATATTGAGAAAAGATGACAAGATAAAAATGGCACTCGATTTATTGCCTAA
AAGCATGTTTGAAGCAATTG

Product: 3'(2'),5'-bisphosphate nucleotidase

Products: NA

Alternate protein names: 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; DPNPase [H]

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MFITTTCPNDALIEQLLPILEEASQILLQEYQNYSAGYEFTIEEKHDDSPVTQADLKVNRFLLKHLAEITPELPVLSEES
DYSARHAWSSCWMLDPLDGTKEFIHERDEFTINLSLIEGRETIFSVIVVPCEQVVYLGYLKDLPFKYSFSQQQWYQYQKT
PYSKQAPVQIGLSHSSKNPKYQKFIEPIEKIRTVIRREAGSAYKFCMMLEGEIDIYPRFHPTSEWDTSSGQGLLESIGGG
LLTLTGKPFEYNQRDTVLNGGFIAFRDQESKKIAFEALAQSGVLD

Sequences:

>Translated_285_residues
MFITTTCPNDALIEQLLPILEEASQILLQEYQNYSAGYEFTIEEKHDDSPVTQADLKVNRFLLKHLAEITPELPVLSEES
DYSARHAWSSCWMLDPLDGTKEFIHERDEFTINLSLIEGRETIFSVIVVPCEQVVYLGYLKDLPFKYSFSQQQWYQYQKT
PYSKQAPVQIGLSHSSKNPKYQKFIEPIEKIRTVIRREAGSAYKFCMMLEGEIDIYPRFHPTSEWDTSSGQGLLESIGGG
LLTLTGKPFEYNQRDTVLNGGFIAFRDQESKKIAFEALAQSGVLD
>Mature_285_residues
MFITTTCPNDALIEQLLPILEEASQILLQEYQNYSAGYEFTIEEKHDDSPVTQADLKVNRFLLKHLAEITPELPVLSEES
DYSARHAWSSCWMLDPLDGTKEFIHERDEFTINLSLIEGRETIFSVIVVPCEQVVYLGYLKDLPFKYSFSQQQWYQYQKT
PYSKQAPVQIGLSHSSKNPKYQKFIEPIEKIRTVIRREAGSAYKFCMMLEGEIDIYPRFHPTSEWDTSSGQGLLESIGGG
LLTLTGKPFEYNQRDTVLNGGFIAFRDQESKKIAFEALAQSGVLD

Specific function: Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP. May also convert adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) [H]

COG id: COG1218

COG function: function code P; 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Escherichia coli, GI1790659, Length=253, Percent_Identity=30.8300395256917, Blast_Score=132, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24664918, Length=259, Percent_Identity=22.7799227799228, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006240
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 32663; Mature: 32663

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS00629 IMP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFITTTCPNDALIEQLLPILEEASQILLQEYQNYSAGYEFTIEEKHDDSPVTQADLKVNR
CEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHH
FLLKHLAEITPELPVLSEESDYSARHAWSSCWMLDPLDGTKEFIHERDEFTINLSLIEGR
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCEEECCCCCHHHHHHCCCCEEEEEEEECCH
ETIFSVIVVPCEQVVYLGYLKDLPFKYSFSQQQWYQYQKTPYSKQAPVQIGLSHSSKNPK
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCEEEEECCCCCCCH
YQKFIEPIEKIRTVIRREAGSAYKFCMMLEGEIDIYPRFHPTSEWDTSSGQGLLESIGGG
HHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCEEEEECCCCCCCCCCCCCCHHHHHCCCC
LLTLTGKPFEYNQRDTVLNGGFIAFRDQESKKIAFEALAQSGVLD
EEEEECCCCCCCCCCEEEECCEEEEECCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure
MFITTTCPNDALIEQLLPILEEASQILLQEYQNYSAGYEFTIEEKHDDSPVTQADLKVNR
CEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHH
FLLKHLAEITPELPVLSEESDYSARHAWSSCWMLDPLDGTKEFIHERDEFTINLSLIEGR
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCEEECCCCCHHHHHHCCCCEEEEEEEECCH
ETIFSVIVVPCEQVVYLGYLKDLPFKYSFSQQQWYQYQKTPYSKQAPVQIGLSHSSKNPK
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCEEEEECCCCCCCH
YQKFIEPIEKIRTVIRREAGSAYKFCMMLEGEIDIYPRFHPTSEWDTSSGQGLLESIGGG
HHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCEEEEECCCCCCCCCCCCCCHHHHHCCCC
LLTLTGKPFEYNQRDTVLNGGFIAFRDQESKKIAFEALAQSGVLD
EEEEECCCCCCCCCCEEEECCEEEEECCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]