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The map label for this gene is ycfH [H]

Identifier: 213157122

GI number: 213157122

Start: 1891254

End: 1892027

Strand: Direct

Name: ycfH [H]

Synonym: AB57_1805

Alternate gene names: 213157122

Gene position: 1891254-1892027 (Clockwise)

Preceding gene: 213157121

Following gene: 213157123

Centisome position: 46.69

GC content: 38.89

Gene sequence:

>774_bases
GTGTTTGTTGATACCCATTGCCATTTAACAATGTTAGATTTAACGCCTTATAACGGTGATTTAGATCTCGCACTTGCTGC
TGCGCGAGCAGAAGGTGTTTCTAAGTTTATGGCAATTTCAGTTGACCTTGATGATCATATGGCTTTAGCTGAAATCGCAA
AGCGTCATGAAGATGTGGGGTATACGGTAGGCGTACATCCGTGTGAGGATGTTGATACTATGGCTCGAGCAACGATTGAG
TATTTGACTGAATTGGCTCAATCGGAAAAGGTATGGGCTTTAGGTGAAACAGGTTTAGACTATTACCACAGCACTGACTT
TATTAACGAGCAAAAAGATTGTTTTGCTCGTCATATTCAAGCCTCTAAAAATGTTAAAAAACCAGTAGTTGTTCATACAC
GTTCAGCAAAACATGATACCGTGGATATTATTCGAGCTGAACAATCTACACATGGTATTTTGCACTGTTTTACTGAGGAC
TGGGAAACAGCAAAAGCTGTATTGGACTGTGGTTACTATATTTCCTTTTCAGGAATTGTTTCATTTAAAAATGCTCAAGA
TCTACGAGATGTAGCCAAGCAAGTTCCTTTAGATCGGCTTTTGATTGAGACAGATAGCCCTTATTTGGCTCCCGTACCAT
ATCGTGGTAAAACGAATGAACCAAAATATGTACCTTATGTAGCGAAAGCACTAAGTGAGGTATATGATAAGCCAGTTGAG
GAAATTGCAAGAATCACCTCGCAGAATTTTGAAAATTTACTTAAAGCGATTTAA

Upstream 100 bases:

>100_bases
ATAAAGGAATTTACTATAAAGCTGAAGCTGAGCGGATTTTAGCTGGTAGTATGTCTTTAGATCGCCCAAGTTATACCATG
TAAGCAGATAGGAAAGAACA

Downstream 100 bases:

>100_bases
CTTATAGAAACTATATAAAGAGAGTAATTGCGTGAAGATGGACCGTCAAGCTCAGTTCCGAGCAAGAGAAGCATTAATAT
TTCAAGTTGCGGAACAGTTG

Product: TatD-related deoxyribonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MFVDTHCHLTMLDLTPYNGDLDLALAAARAEGVSKFMAISVDLDDHMALAEIAKRHEDVGYTVGVHPCEDVDTMARATIE
YLTELAQSEKVWALGETGLDYYHSTDFINEQKDCFARHIQASKNVKKPVVVHTRSAKHDTVDIIRAEQSTHGILHCFTED
WETAKAVLDCGYYISFSGIVSFKNAQDLRDVAKQVPLDRLLIETDSPYLAPVPYRGKTNEPKYVPYVAKALSEVYDKPVE
EIARITSQNFENLLKAI

Sequences:

>Translated_257_residues
MFVDTHCHLTMLDLTPYNGDLDLALAAARAEGVSKFMAISVDLDDHMALAEIAKRHEDVGYTVGVHPCEDVDTMARATIE
YLTELAQSEKVWALGETGLDYYHSTDFINEQKDCFARHIQASKNVKKPVVVHTRSAKHDTVDIIRAEQSTHGILHCFTED
WETAKAVLDCGYYISFSGIVSFKNAQDLRDVAKQVPLDRLLIETDSPYLAPVPYRGKTNEPKYVPYVAKALSEVYDKPVE
EIARITSQNFENLLKAI
>Mature_257_residues
MFVDTHCHLTMLDLTPYNGDLDLALAAARAEGVSKFMAISVDLDDHMALAEIAKRHEDVGYTVGVHPCEDVDTMARATIE
YLTELAQSEKVWALGETGLDYYHSTDFINEQKDCFARHIQASKNVKKPVVVHTRSAKHDTVDIIRAEQSTHGILHCFTED
WETAKAVLDCGYYISFSGIVSFKNAQDLRDVAKQVPLDRLLIETDSPYLAPVPYRGKTNEPKYVPYVAKALSEVYDKPVE
EIARITSQNFENLLKAI

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349734, Length=260, Percent_Identity=28.4615384615385, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI110349730, Length=261, Percent_Identity=28.735632183908, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI226061853, Length=266, Percent_Identity=27.8195488721804, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI225903424, Length=278, Percent_Identity=28.7769784172662, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI226061614, Length=250, Percent_Identity=28, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI14042943, Length=261, Percent_Identity=27.5862068965517, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI226061595, Length=228, Percent_Identity=27.6315789473684, Blast_Score=81, Evalue=7e-16,
Organism=Homo sapiens, GI225903439, Length=244, Percent_Identity=26.6393442622951, Blast_Score=72, Evalue=3e-13,
Organism=Escherichia coli, GI1787342, Length=256, Percent_Identity=47.265625, Blast_Score=234, Evalue=4e-63,
Organism=Escherichia coli, GI87082439, Length=252, Percent_Identity=27.3809523809524, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI48994985, Length=245, Percent_Identity=28.1632653061224, Blast_Score=106, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17559024, Length=271, Percent_Identity=27.6752767527675, Blast_Score=103, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI17543026, Length=211, Percent_Identity=31.7535545023697, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71980746, Length=266, Percent_Identity=27.4436090225564, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17565396, Length=212, Percent_Identity=29.7169811320755, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24648690, Length=263, Percent_Identity=28.5171102661597, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI221330018, Length=271, Percent_Identity=26.5682656826568, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24586117, Length=205, Percent_Identity=30.7317073170732, Blast_Score=81, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 28866; Mature: 28866

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFVDTHCHLTMLDLTPYNGDLDLALAAARAEGVSKFMAISVDLDDHMALAEIAKRHEDVG
CEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHHEEEEEEECCCHHHHHHHHHHHHHCCC
YTVGVHPCEDVDTMARATIEYLTELAQSEKVWALGETGLDYYHSTDFINEQKDCFARHIQ
EEECCCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHCCCCCCHHHHHHHHHHH
ASKNVKKPVVVHTRSAKHDTVDIIRAEQSTHGILHCFTEDWETAKAVLDCGYYISFSGIV
HHCCCCCCEEEEECCCCCCHHHEEECCCCCCCEEEEECCCHHHHHHHHHCCCEEEEECEE
SFKNAQDLRDVAKQVPLDRLLIETDSPYLAPVPYRGKTNEPKYVPYVAKALSEVYDKPVE
EECCHHHHHHHHHHCCHHHEEEECCCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHCHHH
EIARITSQNFENLLKAI
HHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MFVDTHCHLTMLDLTPYNGDLDLALAAARAEGVSKFMAISVDLDDHMALAEIAKRHEDVG
CEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHHEEEEEEECCCHHHHHHHHHHHHHCCC
YTVGVHPCEDVDTMARATIEYLTELAQSEKVWALGETGLDYYHSTDFINEQKDCFARHIQ
EEECCCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHCCCCCCHHHHHHHHHHH
ASKNVKKPVVVHTRSAKHDTVDIIRAEQSTHGILHCFTEDWETAKAVLDCGYYISFSGIV
HHCCCCCCEEEEECCCCCCHHHEEECCCCCCCEEEEECCCHHHHHHHHHCCCEEEEECEE
SFKNAQDLRDVAKQVPLDRLLIETDSPYLAPVPYRGKTNEPKYVPYVAKALSEVYDKPVE
EECCHHHHHHHHHHCCHHHEEEECCCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHCHHH
EIARITSQNFENLLKAI
HHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]