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The map label for this gene is exbB [H]

Identifier: 213157114

GI number: 213157114

Start: 1885305

End: 1885940

Strand: Direct

Name: exbB [H]

Synonym: AB57_1797

Alternate gene names: 213157114

Gene position: 1885305-1885940 (Clockwise)

Preceding gene: 213157113

Following gene: 213157115

Centisome position: 46.54

GC content: 39.31

Gene sequence:

>636_bases
ATGTGGGAACTTGTGAAAGCGGGCGGCTGGTTAATGCTGCCTTTAATTTTGTGTTCAATTTTAACCGTCGCAATTAGTAT
TGAGCGTTTTGTACGTTTAAGACGTTCACAAGTTTTACCTAAAGTACTAATGAATGATGGCAGTGCAGATATTTCTGTTG
TCATAACAAATTTGGAACAGGATACTAATGCGCAAAGCACGGCATTGGGCAATATTCTAAAAGCTGGTTTTGAGCATCAG
GAACATGGCGAACAATTTGCTCGAGCACAAATGGAAGCTATGGCTTCTCAAGAAATCTCTTATTTAGAAAAAAATATTAA
CTTCTTAGGGACCTTAAGTGCTATAGCGCCTCTACTAGGGCTGCTTGGAACAGTTGTGGGAATTATTGAGTCTTTTTGGT
TTATTGATTTTGGTTCGGCAGGTAGTCCTAGTTTAATGATTCCCGGTATTTCCAAGGCTTTGATCACAACAGCAGTTGGT
ATGCTCATTGCAATTCCTGCACTTATTTCCTATCGATATTTTCAAAGAGTAGTGCAAGATTATATTGCTGAGTTAGAGCA
ACAATCGACGCTATTTCATGCCTCATTGTTTTACAAACGTTCTTCAATCATGCAAGAACATCGCCGCGTTGGTTGA

Upstream 100 bases:

>100_bases
CATTCACTCGATGAGTTAGATGGTATTTTGAATATTTGTTTACCAGATTAATTCTAAGTTAGGTCATATATTTCTAATTT
ATATTCTTGGGGAAGAAAAT

Downstream 100 bases:

>100_bases
TGGGTAGATCACAATATGAAGTTTAAACGTTCTCAGGTTGAAGACATTCATATCAATCTAACACCTATGATTGACTGTTT
ATTGTTCATTCTAGTGTTTT

Product: MotA/TolQ/ExbB proton channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MWELVKAGGWLMLPLILCSILTVAISIERFVRLRRSQVLPKVLMNDGSADISVVITNLEQDTNAQSTALGNILKAGFEHQ
EHGEQFARAQMEAMASQEISYLEKNINFLGTLSAIAPLLGLLGTVVGIIESFWFIDFGSAGSPSLMIPGISKALITTAVG
MLIAIPALISYRYFQRVVQDYIAELEQQSTLFHASLFYKRSSIMQEHRRVG

Sequences:

>Translated_211_residues
MWELVKAGGWLMLPLILCSILTVAISIERFVRLRRSQVLPKVLMNDGSADISVVITNLEQDTNAQSTALGNILKAGFEHQ
EHGEQFARAQMEAMASQEISYLEKNINFLGTLSAIAPLLGLLGTVVGIIESFWFIDFGSAGSPSLMIPGISKALITTAVG
MLIAIPALISYRYFQRVVQDYIAELEQQSTLFHASLFYKRSSIMQEHRRVG
>Mature_211_residues
MWELVKAGGWLMLPLILCSILTVAISIERFVRLRRSQVLPKVLMNDGSADISVVITNLEQDTNAQSTALGNILKAGFEHQ
EHGEQFARAQMEAMASQEISYLEKNINFLGTLSAIAPLLGLLGTVVGIIESFWFIDFGSAGSPSLMIPGISKALITTAVG
MLIAIPALISYRYFQRVVQDYIAELEQQSTLFHASLFYKRSSIMQEHRRVG

Specific function: Involved in the tonB-dependent energy-dependent transport of various receptor-bound substrates. Protects exbD from proteolytic degradation and functionally stabilizes tonB [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1786958, Length=117, Percent_Identity=38.4615384615385, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1789381, Length=187, Percent_Identity=30.4812834224599, Blast_Score=69, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898
- InterPro:   IPR014164 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 23334; Mature: 23334

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWELVKAGGWLMLPLILCSILTVAISIERFVRLRRSQVLPKVLMNDGSADISVVITNLEQ
CCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCC
DTNAQSTALGNILKAGFEHQEHGEQFARAQMEAMASQEISYLEKNINFLGTLSAIAPLLG
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLGTVVGIIESFWFIDFGSAGSPSLMIPGISKALITTAVGMLIAIPALISYRYFQRVVQD
HHHHHHHHHHHHHHHCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YIAELEQQSTLFHASLFYKRSSIMQEHRRVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MWELVKAGGWLMLPLILCSILTVAISIERFVRLRRSQVLPKVLMNDGSADISVVITNLEQ
CCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCC
DTNAQSTALGNILKAGFEHQEHGEQFARAQMEAMASQEISYLEKNINFLGTLSAIAPLLG
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLGTVVGIIESFWFIDFGSAGSPSLMIPGISKALITTAVGMLIAIPALISYRYFQRVVQD
HHHHHHHHHHHHHHHCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YIAELEQQSTLFHASLFYKRSSIMQEHRRVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]