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The map label for this gene is hvrB [H]

Identifier: 213157062

GI number: 213157062

Start: 1831466

End: 1832317

Strand: Direct

Name: hvrB [H]

Synonym: AB57_1742

Alternate gene names: 213157062

Gene position: 1831466-1832317 (Clockwise)

Preceding gene: 213157058

Following gene: 213157068

Centisome position: 45.22

GC content: 39.67

Gene sequence:

>852_bases
ATGATTGATTGGGAAAATTTACATTACTTTTCAGTTTTTTCTGAAGAGAAGACACTTTCAGCTGCTGCAAGAAAGTTAGG
TGTTGACCATGCTACTGTTGCAAGAAGAATTGCACAGTTAGAAGATAATTTAAAACTAAAATTAGTGGACCGTAGACCTC
GTACTTATATTTTAACTTCAGAGGGGGAGCATCTGGCCAAAATCGTGACACGTATGATGGAAGAAACATTTTCTATTGAA
CGTCTGGCTCAGGCAGGACAACAGGAAATTAGTGGAGTAGTTTCGGTAAGTCTACCGCCAGCTACGGCTGCACATTTGGT
AATGCCTCATCTTGGTAAGTTTTATCGTCAATATCCTGAGCTGCAATTGAGAATACTTGGTGATGTTCATTATGCCTCCT
TACAGCATCGCGAAGCAGATATCGCAGTTCGCTTTGGACGCCCTAAAGATGATTATCTAATTGCGCGTAAAGCTGGTGAA
GTTCCTTTTGGCATATATGCAGCCCAAGAATATTTGGATGCTATACAAGAAGAAAACTATGAATGGATTAGCGTTGAAGT
TGGTGGAGTTCAAGGACAAAAACAGCAAAAGCTAAAACAACGGTTAAATTATAAAGAGCCTGTTATGGTTACGAATCATC
CTGAGCTTCAATGGCGGGCTACTTGTGGAGCAGTTGGTTTAGCTGTACTACCTGATTTTTTAGGCCAGCAAGGTCATTTA
GTAAAATTACCTGATGATGACCCAATGAGTGCTGAAATTTGGTTAGTAATTCATGAAGATCTGCGGAGTAGTCCTGCAGT
AAGAGTAGTGATGGATTTTCTTTTAGATTGTTTTGAACCTTTTCGTGTTTAA

Upstream 100 bases:

>100_bases
ATTCATGATTGGGCTCCGAAAAAGAATGTCTTTATTCTGAGTAATCACATAAAGGTGTACAATTCCATATTAATTCATCT
CTGATGTGAAAATTTGCACA

Downstream 100 bases:

>100_bases
TATTGCTTAAGCCTTGACTTCAATTAGCTTAATTAATTTTTATTCATCAGGAAAACTTCCTGCATCTTCTCTTGCTTGCT
TCAAGGCTAGAAAAAAACAT

Product: transcriptional regulator, LysR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MIDWENLHYFSVFSEEKTLSAAARKLGVDHATVARRIAQLEDNLKLKLVDRRPRTYILTSEGEHLAKIVTRMMEETFSIE
RLAQAGQQEISGVVSVSLPPATAAHLVMPHLGKFYRQYPELQLRILGDVHYASLQHREADIAVRFGRPKDDYLIARKAGE
VPFGIYAAQEYLDAIQEENYEWISVEVGGVQGQKQQKLKQRLNYKEPVMVTNHPELQWRATCGAVGLAVLPDFLGQQGHL
VKLPDDDPMSAEIWLVIHEDLRSSPAVRVVMDFLLDCFEPFRV

Sequences:

>Translated_283_residues
MIDWENLHYFSVFSEEKTLSAAARKLGVDHATVARRIAQLEDNLKLKLVDRRPRTYILTSEGEHLAKIVTRMMEETFSIE
RLAQAGQQEISGVVSVSLPPATAAHLVMPHLGKFYRQYPELQLRILGDVHYASLQHREADIAVRFGRPKDDYLIARKAGE
VPFGIYAAQEYLDAIQEENYEWISVEVGGVQGQKQQKLKQRLNYKEPVMVTNHPELQWRATCGAVGLAVLPDFLGQQGHL
VKLPDDDPMSAEIWLVIHEDLRSSPAVRVVMDFLLDCFEPFRV
>Mature_283_residues
MIDWENLHYFSVFSEEKTLSAAARKLGVDHATVARRIAQLEDNLKLKLVDRRPRTYILTSEGEHLAKIVTRMMEETFSIE
RLAQAGQQEISGVVSVSLPPATAAHLVMPHLGKFYRQYPELQLRILGDVHYASLQHREADIAVRFGRPKDDYLIARKAGE
VPFGIYAAQEYLDAIQEENYEWISVEVGGVQGQKQQKLKQRLNYKEPVMVTNHPELQWRATCGAVGLAVLPDFLGQQGHL
VKLPDDDPMSAEIWLVIHEDLRSSPAVRVVMDFLLDCFEPFRV

Specific function: Functions as a low-light activator of ahcY expression (gene for S-adenosyl-L-homocysteine hydrolase) and as a high-light activator of a uncharacterized 21.6 kDa protein in the ahcY-hvrB intergenic region (orf5). It is also a negative regulator of its own

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=171, Percent_Identity=26.3157894736842, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1786401, Length=298, Percent_Identity=24.1610738255034, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787589, Length=168, Percent_Identity=24.4047619047619, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788706, Length=143, Percent_Identity=30.0699300699301, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789173, Length=141, Percent_Identity=31.2056737588652, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI145693193, Length=171, Percent_Identity=26.3157894736842, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1788748, Length=161, Percent_Identity=27.3291925465839, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789440, Length=285, Percent_Identity=27.719298245614, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI87081978, Length=295, Percent_Identity=23.728813559322, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32218; Mature: 32218

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDWENLHYFSVFSEEKTLSAAARKLGVDHATVARRIAQLEDNLKLKLVDRRPRTYILTS
CCCCCCEEEEEEECCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEEECCCCEEEEEC
EGEHLAKIVTRMMEETFSIERLAQAGQQEISGVVSVSLPPATAAHLVMPHLGKFYRQYPE
CCHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHCCC
LQLRILGDVHYASLQHREADIAVRFGRPKDDYLIARKAGEVPFGIYAAQEYLDAIQEENY
EEEEEECCHHHHHHHCCCCCEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCC
EWISVEVGGVQGQKQQKLKQRLNYKEPVMVTNHPELQWRATCGAVGLAVLPDFLGQQGHL
EEEEEEECCCCCHHHHHHHHHCCCCCCEEEECCCCEEEEHHHHHHHHHHHHHHHCCCCCE
VKLPDDDPMSAEIWLVIHEDLRSSPAVRVVMDFLLDCFEPFRV
EECCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIDWENLHYFSVFSEEKTLSAAARKLGVDHATVARRIAQLEDNLKLKLVDRRPRTYILTS
CCCCCCEEEEEEECCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEEECCCCEEEEEC
EGEHLAKIVTRMMEETFSIERLAQAGQQEISGVVSVSLPPATAAHLVMPHLGKFYRQYPE
CCHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHCCC
LQLRILGDVHYASLQHREADIAVRFGRPKDDYLIARKAGEVPFGIYAAQEYLDAIQEENY
EEEEEECCHHHHHHHCCCCCEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCC
EWISVEVGGVQGQKQQKLKQRLNYKEPVMVTNHPELQWRATCGAVGLAVLPDFLGQQGHL
EEEEEEECCCCCHHHHHHHHHCCCCCCEEEECCCCEEEEHHHHHHHHHHHHHHHCCCCCE
VKLPDDDPMSAEIWLVIHEDLRSSPAVRVVMDFLLDCFEPFRV
EECCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8282711 [H]