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The map label for this gene is mdcH [H]

Identifier: 213156984

GI number: 213156984

Start: 1747436

End: 1748368

Strand: Direct

Name: mdcH [H]

Synonym: AB57_1660

Alternate gene names: 213156984

Gene position: 1747436-1748368 (Clockwise)

Preceding gene: 213156983

Following gene: 213156985

Centisome position: 43.14

GC content: 42.87

Gene sequence:

>933_bases
ATGGCTTCAATTTGGGTATATCCGGGACAAGGTGTGCAAAGAAGCAATATGTTGCACGACTTACCTCAAACCGCTCTAGT
TAAAGAATACCTTGAGCGTGCATCGGATGCACTCAAAGAAGATGTCTTGATGTTAGATAGTCCAGCTGAATTGCAATCGA
CACGTGCAGTACAGCTTTGTTTACTGATTTCAGGTGTGGTGAGTTCAGCCTTATTAACAGCGGAAAACTTAACACCAGAT
TATGTAGCAGGTTTATCAATTGGTGCATGGTCAGCGGCGGTTGTAGCAGGAGTTTTAGCCTTTGAGGATGCCGTTCGTTT
GGTTGCCTATCGAGGTGAACTTATGCAAAACGCCTATCCAATTGGCTATGGTATGACTGCTCTGATTGGTACAGACCGTG
CAACTGTTGAAACATGGGTCAAAAAGATTTATGAAATAACGCCAGAGGTGTTTGTCGCAAATATTAATGCACATAACCAG
ATCGTTATTTCAGGAAGCTTTGAAGCCATGACTCAAGTTGCTGTTTTGGCGAAGCAACAAGGCGTGGTAGCAAAAAAATT
AGATGTATCGGTGCCATCGCACTGTGAATTATTAAGTCAGCAAGCAAAGCAACTTGCAGCGTCTATGGAGGAAGTGACTT
TAAAGCAGCCTAAAATACGTTATTTAAGTGGTACAACGGCTCGTACGCTTAGCAGGCCAGAACTGATTGGTGATGACTTG
GCTTTTAATATGAGTCGAACTGTAGATTGGGAAAGTACCATCCAAGCTGCATGGGAGCGAGGTGTAAGGTTACAGATCGA
AGCTTTGCCGGGAACGGTGCTTACTACACTTGCACGTCGAACATTTAAAGAAGGAACTGTATTGTCATTTCAGGGAACAC
GTTTAGACAGCATTCAGTTAGCAATGCAAAATGAAAATAATGCTTCTTTGTAA

Upstream 100 bases:

>100_bases
TGGCGTTAAAAGAATGGGCTGGGAATAGCGTAAAAGTTCTATTGAAACGTCCTGATGGTGCTTTTTTATTAGAAAACCCA
TGGAATTAGGGATAGATATC

Downstream 100 bases:

>100_bases
TTACAATACAAATTAAAAATTGAGTAATAACCCAAGGATATGAGGGATTTACAATGATTATTTATGGAACAGCAATATTA
GCGATCTGCCATTTATTAGG

Product: malonate decarboxylase, epsilon subunit

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 310; Mature: 309

Protein sequence:

>310_residues
MASIWVYPGQGVQRSNMLHDLPQTALVKEYLERASDALKEDVLMLDSPAELQSTRAVQLCLLISGVVSSALLTAENLTPD
YVAGLSIGAWSAAVVAGVLAFEDAVRLVAYRGELMQNAYPIGYGMTALIGTDRATVETWVKKIYEITPEVFVANINAHNQ
IVISGSFEAMTQVAVLAKQQGVVAKKLDVSVPSHCELLSQQAKQLAASMEEVTLKQPKIRYLSGTTARTLSRPELIGDDL
AFNMSRTVDWESTIQAAWERGVRLQIEALPGTVLTTLARRTFKEGTVLSFQGTRLDSIQLAMQNENNASL

Sequences:

>Translated_310_residues
MASIWVYPGQGVQRSNMLHDLPQTALVKEYLERASDALKEDVLMLDSPAELQSTRAVQLCLLISGVVSSALLTAENLTPD
YVAGLSIGAWSAAVVAGVLAFEDAVRLVAYRGELMQNAYPIGYGMTALIGTDRATVETWVKKIYEITPEVFVANINAHNQ
IVISGSFEAMTQVAVLAKQQGVVAKKLDVSVPSHCELLSQQAKQLAASMEEVTLKQPKIRYLSGTTARTLSRPELIGDDL
AFNMSRTVDWESTIQAAWERGVRLQIEALPGTVLTTLARRTFKEGTVLSFQGTRLDSIQLAMQNENNASL
>Mature_309_residues
ASIWVYPGQGVQRSNMLHDLPQTALVKEYLERASDALKEDVLMLDSPAELQSTRAVQLCLLISGVVSSALLTAENLTPDY
VAGLSIGAWSAAVVAGVLAFEDAVRLVAYRGELMQNAYPIGYGMTALIGTDRATVETWVKKIYEITPEVFVANINAHNQI
VISGSFEAMTQVAVLAKQQGVVAKKLDVSVPSHCELLSQQAKQLAASMEEVTLKQPKIRYLSGTTARTLSRPELIGDDLA
FNMSRTVDWESTIQAAWERGVRLQIEALPGTVLTTLARRTFKEGTVLSFQGTRLDSIQLAMQNENNASL

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=298, Percent_Identity=26.510067114094, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1787334, Length=286, Percent_Identity=34.6153846153846, Blast_Score=129, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17550940, Length=283, Percent_Identity=26.8551236749117, Blast_Score=87, Evalue=9e-18,
Organism=Drosophila melanogaster, GI24665753, Length=310, Percent_Identity=27.741935483871, Blast_Score=87, Evalue=2e-17,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 33771; Mature: 33640

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASIWVYPGQGVQRSNMLHDLPQTALVKEYLERASDALKEDVLMLDSPAELQSTRAVQLC
CCEEEEECCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHH
LLISGVVSSALLTAENLTPDYVAGLSIGAWSAAVVAGVLAFEDAVRLVAYRGELMQNAYP
HHHHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
IGYGMTALIGTDRATVETWVKKIYEITPEVFVANINAHNQIVISGSFEAMTQVAVLAKQQ
CCCCCEEEECCCHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEECCHHHHHHHHHHHHHC
GVVAKKLDVSVPSHCELLSQQAKQLAASMEEVTLKQPKIRYLSGTTARTLSRPELIGDDL
CCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHCCCCHHCCCCH
AFNMSRTVDWESTIQAAWERGVRLQIEALPGTVLTTLARRTFKEGTVLSFQGTRLDSIQL
HCCCCCCCCHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHCCCCEEEECCCCCCEEEE
AMQNENNASL
EEECCCCCCC
>Mature Secondary Structure 
ASIWVYPGQGVQRSNMLHDLPQTALVKEYLERASDALKEDVLMLDSPAELQSTRAVQLC
CEEEEECCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHH
LLISGVVSSALLTAENLTPDYVAGLSIGAWSAAVVAGVLAFEDAVRLVAYRGELMQNAYP
HHHHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
IGYGMTALIGTDRATVETWVKKIYEITPEVFVANINAHNQIVISGSFEAMTQVAVLAKQQ
CCCCCEEEECCCHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEECCHHHHHHHHHHHHHC
GVVAKKLDVSVPSHCELLSQQAKQLAASMEEVTLKQPKIRYLSGTTARTLSRPELIGDDL
CCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHCCCCHHCCCCH
AFNMSRTVDWESTIQAAWERGVRLQIEALPGTVLTTLARRTFKEGTVLSFQGTRLDSIQL
HCCCCCCCCHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHCCCCEEEECCCCCCEEEE
AMQNENNASL
EEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]