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The map label for this gene is phnW [H]

Identifier: 213156901

GI number: 213156901

Start: 1655633

End: 1656820

Strand: Direct

Name: phnW [H]

Synonym: AB57_1572

Alternate gene names: 213156901

Gene position: 1655633-1656820 (Clockwise)

Preceding gene: 213156900

Following gene: 213156902

Centisome position: 40.87

GC content: 41.67

Gene sequence:

>1188_bases
ATGTATATTGAAATGAACGCGAAAGAAATGAGTAACATTATGAACATGCAACCCCAACTCGATATGGATTTAGAGAACAA
GTATTTGCTCCTTACTCCAGGACCATTATCAACATCGGCAACAGTACGCCGTGCCATGCAAAAAGACTGGTGTACTTGGG
ACCAAGAATACAACTCACTGGTACAAGATATCCGCTCTCGTCTAGTCAACTTGGCGACCAGTCAACCTGAAAAATATACG
GCTGTGTTAATGCAAGGCAGTGGTAGTTTTGCGGTTGAGTCTGTACTTGGTTCAGCTATTCCACGTGATGGCAAAATCTT
GATCATTAATAATGGCGCATATGGTGCACGTATGGTGCAAATGGCGCGTTGCCTAAATATTGAAGTGATCGAGCTGAACT
ATTTAGAAACCCAAACACCAGATTTACAAGAAGTTGAGCGTGTTTTAAAAGATAAAACCATTAGTCATGTTGCTTGTGTG
CACTGTGAAACCACTACTGGTATTTTAAACCCGATTCAAGAGATAGGCCGTTTAGTTAAAGCGGCAGGAAAAATCTGGAT
TGTGGATGCCATGAGTTCATTTGGTGGAGTACCTATGGATATGGCTGAGCTTGAAATTGATTTTCTAATTTCAAGTGCAA
ATAAATGTATTCAAGGTGTTCCGGGCTTTGGCTTTATTTTGGCAAAGCGTGATTGCCTAGAAGCATGTAAAGGCTTGGCA
CGTTCGGACAGTCTCGATTTGTATGACCAGTGGAATACGATGGAGCAGCATAACGGTAAATGGCGTTTTACCTCGCCAAC
CCATGTGGTACGTGCATTTTATCAAGCATTACTTGAGCTTGAGACAGAAGGCGGTGTTGCTGCACGTTATCAACGTTATT
TACAAAACCAACAAACCTTATCTAAAGGTATGCAACAACTTGGCTTTGAATTGGTGCTCGGTGAAGAGTGCCCACAATCA
CCCATCATTACCACTTTCCTTTACCCAACAGCCGAGAAATTTAGCTTTCAGTCATTCTATGAAACGCTAAAAAAATCAGG
CTATGTAATTTATCCGGGCAAAGTCACAGATCTTAACTGCTTCCGTATAGGCAATATTGGCGAAGTTTATATTCATGACA
TTGAAGGGCTTCTTGCTGCTATTGCCAGCTACTGCGAAAACCACCTAAACCAAGCTGTAACAGTATAA

Upstream 100 bases:

>100_bases
GTGCAATTGCTGGTAAAGGCATGACCACGGGGGCTGGATTTATGAAAGATGTATTGGAACAAAATATTTACTAGTTTGTC
ATCTGGTTTAAACCAGATTG

Downstream 100 bases:

>100_bases
TTTTTATTAAATTAAGGGGAATACACCATGACGACCAACAATACACAAATTCAGGCTGTGGTTTTTGACTGGGCTGGTAC
AACTGTAGATTTTGGCTCAC

Product: 2-aminoethylphosphonate--pyruvate transaminase

Products: NA

Alternate protein names: 2-aminoethylphosphonate aminotransferase; AEP transaminase; AEPT [H]

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MYIEMNAKEMSNIMNMQPQLDMDLENKYLLLTPGPLSTSATVRRAMQKDWCTWDQEYNSLVQDIRSRLVNLATSQPEKYT
AVLMQGSGSFAVESVLGSAIPRDGKILIINNGAYGARMVQMARCLNIEVIELNYLETQTPDLQEVERVLKDKTISHVACV
HCETTTGILNPIQEIGRLVKAAGKIWIVDAMSSFGGVPMDMAELEIDFLISSANKCIQGVPGFGFILAKRDCLEACKGLA
RSDSLDLYDQWNTMEQHNGKWRFTSPTHVVRAFYQALLELETEGGVAARYQRYLQNQQTLSKGMQQLGFELVLGEECPQS
PIITTFLYPTAEKFSFQSFYETLKKSGYVIYPGKVTDLNCFRIGNIGEVYIHDIEGLLAAIASYCENHLNQAVTV

Sequences:

>Translated_395_residues
MYIEMNAKEMSNIMNMQPQLDMDLENKYLLLTPGPLSTSATVRRAMQKDWCTWDQEYNSLVQDIRSRLVNLATSQPEKYT
AVLMQGSGSFAVESVLGSAIPRDGKILIINNGAYGARMVQMARCLNIEVIELNYLETQTPDLQEVERVLKDKTISHVACV
HCETTTGILNPIQEIGRLVKAAGKIWIVDAMSSFGGVPMDMAELEIDFLISSANKCIQGVPGFGFILAKRDCLEACKGLA
RSDSLDLYDQWNTMEQHNGKWRFTSPTHVVRAFYQALLELETEGGVAARYQRYLQNQQTLSKGMQQLGFELVLGEECPQS
PIITTFLYPTAEKFSFQSFYETLKKSGYVIYPGKVTDLNCFRIGNIGEVYIHDIEGLLAAIASYCENHLNQAVTV
>Mature_395_residues
MYIEMNAKEMSNIMNMQPQLDMDLENKYLLLTPGPLSTSATVRRAMQKDWCTWDQEYNSLVQDIRSRLVNLATSQPEKYT
AVLMQGSGSFAVESVLGSAIPRDGKILIINNGAYGARMVQMARCLNIEVIELNYLETQTPDLQEVERVLKDKTISHVACV
HCETTTGILNPIQEIGRLVKAAGKIWIVDAMSSFGGVPMDMAELEIDFLISSANKCIQGVPGFGFILAKRDCLEACKGLA
RSDSLDLYDQWNTMEQHNGKWRFTSPTHVVRAFYQALLELETEGGVAARYQRYLQNQQTLSKGMQQLGFELVLGEECPQS
PIITTFLYPTAEKFSFQSFYETLKKSGYVIYPGKVTDLNCFRIGNIGEVYIHDIEGLLAAIASYCENHLNQAVTV

Specific function: Involved in phosphonate degradation [H]

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557289, Length=317, Percent_Identity=24.6056782334385, Blast_Score=75, Evalue=9e-14,
Organism=Escherichia coli, GI48994898, Length=171, Percent_Identity=29.2397660818713, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17536281, Length=346, Percent_Identity=22.5433526011561, Blast_Score=96, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017688
- InterPro:   IPR000192
- InterPro:   IPR012703
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.37 [H]

Molecular weight: Translated: 44282; Mature: 44282

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYIEMNAKEMSNIMNMQPQLDMDLENKYLLLTPGPLSTSATVRRAMQKDWCTWDQEYNSL
CEEECCHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHH
VQDIRSRLVNLATSQPEKYTAVLMQGSGSFAVESVLGSAIPRDGKILIINNGAYGARMVQ
HHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHCCCCCCEEEEEECCCCHHHHHH
MARCLNIEVIELNYLETQTPDLQEVERVLKDKTISHVACVHCETTTGILNPIQEIGRLVK
HHHHCCEEEEEEEECCCCCCCHHHHHHHHHHCCHHHEEEEEECCHHHHHHHHHHHHHHHH
AAGKIWIVDAMSSFGGVPMDMAELEIDFLISSANKCIQGVPGFGFILAKRDCLEACKGLA
HCCCEEEEEEHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHCCC
RSDSLDLYDQWNTMEQHNGKWRFTSPTHVVRAFYQALLELETEGGVAARYQRYLQNQQTL
CCCCCCHHHHHCCHHHCCCCEEECCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
SKGMQQLGFELVLGEECPQSPIITTFLYPTAEKFSFQSFYETLKKSGYVIYPGKVTDLNC
HHHHHHCCCEEEECCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCEEEECCCCCCCCE
FRIGNIGEVYIHDIEGLLAAIASYCENHLNQAVTV
EEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MYIEMNAKEMSNIMNMQPQLDMDLENKYLLLTPGPLSTSATVRRAMQKDWCTWDQEYNSL
CEEECCHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHH
VQDIRSRLVNLATSQPEKYTAVLMQGSGSFAVESVLGSAIPRDGKILIINNGAYGARMVQ
HHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHCCCCCCEEEEEECCCCHHHHHH
MARCLNIEVIELNYLETQTPDLQEVERVLKDKTISHVACVHCETTTGILNPIQEIGRLVK
HHHHCCEEEEEEEECCCCCCCHHHHHHHHHHCCHHHEEEEEECCHHHHHHHHHHHHHHHH
AAGKIWIVDAMSSFGGVPMDMAELEIDFLISSANKCIQGVPGFGFILAKRDCLEACKGLA
HCCCEEEEEEHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHCCC
RSDSLDLYDQWNTMEQHNGKWRFTSPTHVVRAFYQALLELETEGGVAARYQRYLQNQQTL
CCCCCCHHHHHCCHHHCCCCEEECCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
SKGMQQLGFELVLGEECPQSPIITTFLYPTAEKFSFQSFYETLKKSGYVIYPGKVTDLNC
HHHHHHCCCEEEECCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCEEEECCCCCCCCE
FRIGNIGEVYIHDIEGLLAAIASYCENHLNQAVTV
EEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA