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The map label for this gene is ttuB [H]

Identifier: 213156877

GI number: 213156877

Start: 1631117

End: 1632433

Strand: Direct

Name: ttuB [H]

Synonym: AB57_1548

Alternate gene names: 213156877

Gene position: 1631117-1632433 (Clockwise)

Preceding gene: 213156876

Following gene: 213156878

Centisome position: 40.27

GC content: 39.71

Gene sequence:

>1317_bases
ATGAGTTTAACGCAAAGCATGGAATTATCGGCTGAAGCAATTGCTGAAAAGCAATTAAATAAAAAAGTAGCATGGAAAAT
CATGCCATTAATTATGGTGTGTTACTTATTTGTCTTTTTTGATCGTATCAACATTAGTTTTGCCAAGTTTCAGTTACAAG
CTGATTTATCTCTAAGCAATACAGCTTATGGCCTTGGTGCCAGTTTGTTTGTAATTGGGTATGTAATATTTGAAGTACCG
AGTAATTTATTGCTACATAAATTTGGTGCAAGAAAATGGATTGCACGCATCATGATTTCTTGGGGTGTTGCAACGGCCTT
AATGGTATTTGTGACCACAGAGTGGCAATTTTATGTATTACGTTTCTTGATTGGTGCAATGGAGGCTGGCTTTGCTCCGG
GTGTGCTGTATTACATGACGCTTTGGTTTCCTCAAAGCTATCGTGGTCGAATTATTTCATTATTTTTCCTTGCTTCTGCT
TTTTCAGGCATCTTTGGAGGGCCAATTTCAGGAGTGTTATTGTCATCACTTGATGGTGTGATGAACATGCGTGGCTGGCA
TTGGTTATTTTTAGTCGGTGGCGTGCCTTGCGTTTTATTGGGTCTTTGTGTTCTTACTTATTTAAAAGATCGTATTGATG
ATGCGCAATGGCTATCATCCTCAGAAAAAGTTCACTTAAAACGTTTGGTTGAACCTAAACAACCTGAAAAGGCCTCTCAT
TCATTATGGGCTGCCATTAAAACTCCGGGATTATTAATTTTAGGTGCTATCTATTTTCTGATTCAGATTGCATCTTATGG
TTTAAATTTCTGGGGGCCACAGTTAATAAAAAGCTCAGGTATTGATGATACCCAAATGATTGGTTTTCTTAGTGCCATTC
CATACCTCATGGGAGCAATTACAATGGTAATTGTTGGACGTTTAGCAGATAAATCTGGGGAGCGTTTAAAATTTACTGCT
GGTTTACTCTCTTTAGGTGCTATTGGTTTCTTTACCGCCGGTTTCTTTGATGCGAACCCCGTTGTTGTGGTCATTTCGCT
TGCTTTATTAGGGGCAGGTATTGTTGCTGCAATTCCTTCTTTCTGGAATTTACCACCTAAAGTCTTGGTCGGAGCTGGGG
CGGGGGCTGCGGGTGGTACAGCGCTCATTAATACATTAGGGCAAGTAGGGGGAATTGTTAGTCCTATTATGGTTGGTCAT
ATTAAAGACATAACAGGGAGTACAACGCCTGCGCTGTATATTATTGCAAGCTTATGTGTTGTGTGTATTGCACTACTAAT
ATGGGCTACGCCAAAACGGTTAAAAGAGAAAGGTTAA

Upstream 100 bases:

>100_bases
AGATAGTTGGAAATGAGACGATATTTGTATCGTCATCGGTCAACTCGTCTTTAAAAACTTGATAGGACGCGTCTTGAGGC
TCATTTTCAGGAGAAAATAA

Downstream 100 bases:

>100_bases
ACGATTCACTCATGCTCAAAGCCAGTTGGTTGGCTGGGCATGAGTGCAGTTAATATGAAAATGATCTAATAGTTAAAAAA
TAAAACTTATAGCCAACTTA

Product: major facilitator superfamily MFS_1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 438; Mature: 437

Protein sequence:

>438_residues
MSLTQSMELSAEAIAEKQLNKKVAWKIMPLIMVCYLFVFFDRINISFAKFQLQADLSLSNTAYGLGASLFVIGYVIFEVP
SNLLLHKFGARKWIARIMISWGVATALMVFVTTEWQFYVLRFLIGAMEAGFAPGVLYYMTLWFPQSYRGRIISLFFLASA
FSGIFGGPISGVLLSSLDGVMNMRGWHWLFLVGGVPCVLLGLCVLTYLKDRIDDAQWLSSSEKVHLKRLVEPKQPEKASH
SLWAAIKTPGLLILGAIYFLIQIASYGLNFWGPQLIKSSGIDDTQMIGFLSAIPYLMGAITMVIVGRLADKSGERLKFTA
GLLSLGAIGFFTAGFFDANPVVVVISLALLGAGIVAAIPSFWNLPPKVLVGAGAGAAGGTALINTLGQVGGIVSPIMVGH
IKDITGSTTPALYIIASLCVVCIALLIWATPKRLKEKG

Sequences:

>Translated_438_residues
MSLTQSMELSAEAIAEKQLNKKVAWKIMPLIMVCYLFVFFDRINISFAKFQLQADLSLSNTAYGLGASLFVIGYVIFEVP
SNLLLHKFGARKWIARIMISWGVATALMVFVTTEWQFYVLRFLIGAMEAGFAPGVLYYMTLWFPQSYRGRIISLFFLASA
FSGIFGGPISGVLLSSLDGVMNMRGWHWLFLVGGVPCVLLGLCVLTYLKDRIDDAQWLSSSEKVHLKRLVEPKQPEKASH
SLWAAIKTPGLLILGAIYFLIQIASYGLNFWGPQLIKSSGIDDTQMIGFLSAIPYLMGAITMVIVGRLADKSGERLKFTA
GLLSLGAIGFFTAGFFDANPVVVVISLALLGAGIVAAIPSFWNLPPKVLVGAGAGAAGGTALINTLGQVGGIVSPIMVGH
IKDITGSTTPALYIIASLCVVCIALLIWATPKRLKEKG
>Mature_437_residues
SLTQSMELSAEAIAEKQLNKKVAWKIMPLIMVCYLFVFFDRINISFAKFQLQADLSLSNTAYGLGASLFVIGYVIFEVPS
NLLLHKFGARKWIARIMISWGVATALMVFVTTEWQFYVLRFLIGAMEAGFAPGVLYYMTLWFPQSYRGRIISLFFLASAF
SGIFGGPISGVLLSSLDGVMNMRGWHWLFLVGGVPCVLLGLCVLTYLKDRIDDAQWLSSSEKVHLKRLVEPKQPEKASHS
LWAAIKTPGLLILGAIYFLIQIASYGLNFWGPQLIKSSGIDDTQMIGFLSAIPYLMGAITMVIVGRLADKSGERLKFTAG
LLSLGAIGFFTAGFFDANPVVVVISLALLGAGIVAAIPSFWNLPPKVLVGAGAGAAGGTALINTLGQVGGIVSPIMVGHI
KDITGSTTPALYIIASLCVVCIALLIWATPKRLKEKG

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Escherichia coli, GI87082071, Length=402, Percent_Identity=34.0796019900498, Blast_Score=234, Evalue=1e-62,
Organism=Escherichia coli, GI1789152, Length=463, Percent_Identity=26.7818574514039, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1789515, Length=455, Percent_Identity=24.1758241758242, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI2367379, Length=406, Percent_Identity=25.1231527093596, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI87082320, Length=414, Percent_Identity=24.6376811594203, Blast_Score=75, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17560030, Length=354, Percent_Identity=23.728813559322, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6321698, Length=323, Percent_Identity=23.8390092879257, Blast_Score=77, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6322025, Length=206, Percent_Identity=26.2135922330097, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6322612, Length=251, Percent_Identity=23.9043824701195, Blast_Score=70, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6319876, Length=252, Percent_Identity=23.015873015873, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6323032, Length=234, Percent_Identity=25.2136752136752, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24584153, Length=368, Percent_Identity=24.4565217391304, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47435; Mature: 47304

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLTQSMELSAEAIAEKQLNKKVAWKIMPLIMVCYLFVFFDRINISFAKFQLQADLSLSN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCC
TAYGLGASLFVIGYVIFEVPSNLLLHKFGARKWIARIMISWGVATALMVFVTTEWQFYVL
CHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
RFLIGAMEAGFAPGVLYYMTLWFPQSYRGRIISLFFLASAFSGIFGGPISGVLLSSLDGV
HHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
MNMRGWHWLFLVGGVPCVLLGLCVLTYLKDRIDDAQWLSSSEKVHLKRLVEPKQPEKASH
HHCCCCEEEHHHHCHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHCCCCCCCHHHH
SLWAAIKTPGLLILGAIYFLIQIASYGLNFWGPQLIKSSGIDDTQMIGFLSAIPYLMGAI
HHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHH
TMVIVGRLADKSGERLKFTAGLLSLGAIGFFTAGFFDANPVVVVISLALLGAGIVAAIPS
HHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
FWNLPPKVLVGAGAGAAGGTALINTLGQVGGIVSPIMVGHIKDITGSTTPALYIIASLCV
HHCCCHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
VCIALLIWATPKRLKEKG
HHHHHHHHCCCHHHHCCC
>Mature Secondary Structure 
SLTQSMELSAEAIAEKQLNKKVAWKIMPLIMVCYLFVFFDRINISFAKFQLQADLSLSN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCC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HHHHHHHHCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]