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The map label for this gene is glyQ

Identifier: 21244928

GI number: 21244928

Start: 4961621

End: 4962529

Strand: Reverse

Name: glyQ

Synonym: XAC4211

Alternate gene names: 21244928

Gene position: 4962529-4961621 (Counterclockwise)

Preceding gene: 21244930

Following gene: 21244927

Centisome position: 95.88

GC content: 64.36

Gene sequence:

>909_bases
ATGTCCGATTCCCGGCGCGTTCCAATCACTTTCCAGGGCCTGATCCAGACCCTCAACCAGTACTGGGCCGAACAGGGCTG
CGTGCTGATCCAGCCGCTGGACCTGGAAGTGGGCGCGGGCACGTTCCATCCGGCCACCTTCCTGCGCGCGCTGGGGCCCG
AGCCGTGGAATGCGGCCTATGTGCAGCCTTCGCGCCGTCCCACCGATGGCCGCTATGGCGAAAATCCCAATCGCCTGCAG
CGTTATTACCAGTACCAGGTGGCGATGAAGCCCAATCCGGACAACATCCAGGACCTGTATCTGGGCTCGTTGCAGGCGCT
GGGCATCGACCCGTTGGTGCACGACCTGCGTTTTGTCGAGGACAACTGGGAATCGCCCACGCTCGGCGCCTGGGGCCTGG
GCTGGGAAGTCTGGCTCAATGGCATGGAAGTGACCCAGTTCACCTACTTCCAGCAGGCCGGCGGACTGGAGTGCAAACCG
GTGCTGGGCGAGATCACCTACGGTCTGGAACGGCTGTGCATGTATCTGCAGAGCTGCGACAACGTCTATGAACTGGTGTG
GACCTACGGCCCGGACGGAGCGGCGGTCACGTACGGCGATGTGTACCACCAGAACGAGGTGGAGCAGAGCACCTACAACT
TCGAACACGCCAATGTGGCCGAGCTGTTCCATCGCTTCGACGCCTGCGAAGCCGAAGCCAGGCACCTGGTCGAGGTCGGC
CTGCCGCTGCCGGCGTACGAGCAGGTCACCAAGGCCAGCCACGCCTTCAACCTGCTGGATGCGCGCCGCGCGATCAGCGT
CACCGAACGCCAGCGCTACATCCTGCGCGTGCGCGCGCTGGCCCAGGGCGTGGCGCAGGCGTACTACGCCCAGCGCGAGA
AGCTCGGCTTTCCCGGCGTCAAACGTTGA

Upstream 100 bases:

>100_bases
GCTGTTCCATGCGTGTTCTTCCCCAGCAGCGGTGCTGCGCGGCAAAGCGCCGCGGGTCGGCCGGTATACTAGCGCACCCC
TTCCGTACGGCCTTTGCTGC

Downstream 100 bases:

>100_bases
TGCCGGCGACTTGCTGATGCAGTTCCCTTCCCTCGCTCGCGGGGGAAGGTGCCCGAAGGGCGGATGGGGGCAGTACGCCA
TCCCACCTGGCACGACCCTC

Product: glycyl-tRNA synthetase subunit alpha

Products: NA

Alternate protein names: Glycine--tRNA ligase alpha subunit; GlyRS

Number of amino acids: Translated: 302; Mature: 301

Protein sequence:

>302_residues
MSDSRRVPITFQGLIQTLNQYWAEQGCVLIQPLDLEVGAGTFHPATFLRALGPEPWNAAYVQPSRRPTDGRYGENPNRLQ
RYYQYQVAMKPNPDNIQDLYLGSLQALGIDPLVHDLRFVEDNWESPTLGAWGLGWEVWLNGMEVTQFTYFQQAGGLECKP
VLGEITYGLERLCMYLQSCDNVYELVWTYGPDGAAVTYGDVYHQNEVEQSTYNFEHANVAELFHRFDACEAEARHLVEVG
LPLPAYEQVTKASHAFNLLDARRAISVTERQRYILRVRALAQGVAQAYYAQREKLGFPGVKR

Sequences:

>Translated_302_residues
MSDSRRVPITFQGLIQTLNQYWAEQGCVLIQPLDLEVGAGTFHPATFLRALGPEPWNAAYVQPSRRPTDGRYGENPNRLQ
RYYQYQVAMKPNPDNIQDLYLGSLQALGIDPLVHDLRFVEDNWESPTLGAWGLGWEVWLNGMEVTQFTYFQQAGGLECKP
VLGEITYGLERLCMYLQSCDNVYELVWTYGPDGAAVTYGDVYHQNEVEQSTYNFEHANVAELFHRFDACEAEARHLVEVG
LPLPAYEQVTKASHAFNLLDARRAISVTERQRYILRVRALAQGVAQAYYAQREKLGFPGVKR
>Mature_301_residues
SDSRRVPITFQGLIQTLNQYWAEQGCVLIQPLDLEVGAGTFHPATFLRALGPEPWNAAYVQPSRRPTDGRYGENPNRLQR
YYQYQVAMKPNPDNIQDLYLGSLQALGIDPLVHDLRFVEDNWESPTLGAWGLGWEVWLNGMEVTQFTYFQQAGGLECKPV
LGEITYGLERLCMYLQSCDNVYELVWTYGPDGAAVTYGDVYHQNEVEQSTYNFEHANVAELFHRFDACEAEARHLVEVGL
PLPAYEQVTKASHAFNLLDARRAISVTERQRYILRVRALAQGVAQAYYAQREKLGFPGVKR

Specific function: Unknown

COG id: COG0752

COG function: function code J; Glycyl-tRNA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Escherichia coli, GI1789983, Length=295, Percent_Identity=73.8983050847458, Blast_Score=457, Evalue=1e-130,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SYGA_XANAC (Q8PEX9)

Other databases:

- EMBL:   AE008923
- RefSeq:   NP_644510.1
- ProteinModelPortal:   Q8PEX9
- SMR:   Q8PEX9
- GeneID:   1158282
- GenomeReviews:   AE008923_GR
- KEGG:   xac:XAC4211
- NMPDR:   fig|190486.1.peg.4154
- HOGENOM:   HBG285316
- OMA:   CRRPTDG
- ProtClustDB:   PRK09348
- BioCyc:   XAXO190486:XAC4211-MONOMER
- BRENDA:   6.1.1.14
- GO:   GO:0005737
- HAMAP:   MF_00254
- InterPro:   IPR006194
- InterPro:   IPR002310
- PRINTS:   PR01044
- TIGRFAMs:   TIGR00388

Pfam domain/function: PF02091 tRNA-synt_2e

EC number: =6.1.1.14

Molecular weight: Translated: 34390; Mature: 34259

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS50861 AA_TRNA_LIGASE_II_GLYAB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDSRRVPITFQGLIQTLNQYWAEQGCVLIQPLDLEVGAGTFHPATFLRALGPEPWNAAY
CCCCCCCCEEHHHHHHHHHHHHHHCCCEEEEECCEEECCCCCCHHHHHHHHCCCCCCCEE
VQPSRRPTDGRYGENPNRLQRYYQYQVAMKPNPDNIQDLYLGSLQALGIDPLVHDLRFVE
ECCCCCCCCCCCCCCHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHH
DNWESPTLGAWGLGWEVWLNGMEVTQFTYFQQAGGLECKPVLGEITYGLERLCMYLQSCD
CCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCC
NVYELVWTYGPDGAAVTYGDVYHQNEVEQSTYNFEHANVAELFHRFDACEAEARHLVEVG
CCEEEEEEECCCCCEEEECHHHHCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
LPLPAYEQVTKASHAFNLLDARRAISVTERQRYILRVRALAQGVAQAYYAQREKLGFPGV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
KR
CC
>Mature Secondary Structure 
SDSRRVPITFQGLIQTLNQYWAEQGCVLIQPLDLEVGAGTFHPATFLRALGPEPWNAAY
CCCCCCCEEHHHHHHHHHHHHHHCCCEEEEECCEEECCCCCCHHHHHHHHCCCCCCCEE
VQPSRRPTDGRYGENPNRLQRYYQYQVAMKPNPDNIQDLYLGSLQALGIDPLVHDLRFVE
ECCCCCCCCCCCCCCHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHH
DNWESPTLGAWGLGWEVWLNGMEVTQFTYFQQAGGLECKPVLGEITYGLERLCMYLQSCD
CCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCC
NVYELVWTYGPDGAAVTYGDVYHQNEVEQSTYNFEHANVAELFHRFDACEAEARHLVEVG
CCEEEEEEECCCCCEEEECHHHHCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
LPLPAYEQVTKASHAFNLLDARRAISVTERQRYILRVRALAQGVAQAYYAQREKLGFPGV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
KR
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217