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The map label for this gene is bioC [C]

Identifier: 21244842

GI number: 21244842

Start: 4844967

End: 4846298

Strand: Reverse

Name: bioC [C]

Synonym: XAC4125

Alternate gene names: 21244842

Gene position: 4846298-4844967 (Counterclockwise)

Preceding gene: 21244843

Following gene: 21244841

Centisome position: 93.64

GC content: 68.54

Gene sequence:

>1332_bases
ATGCAAACTGCGACCCAGCCACACCCCGAGGCACTGCAGCAGGCGATCGCCGCGCACCGCAGTGGCCGACTCGAACATGC
CGCGCAGCTGTACACGCAGCTGCTGGACGATCAGCCCGGGCATGCCGACGCGCTGCATTACCAGGGCATCCTGCTGCATC
AGCGCGGCAACAGCGCCGCAGCGGTGGCCTCCATCACCCAGGCGTTGACGCTGGCGCCCGCGCAACCGGATGCCTGCAAC
AACCTGGGCAACGTGCACCGCGAATGCGGCCGCCTGCGCGATGCCGAACGCTGCTATCGCCGCGCGCTGGCGCTGGCGCC
TGCGCATGCCGATGCACTGGCGAATCTGGCAGCGGTACTGGAAGCGCAGCGGCGCGGCGAAGAAGCCTTCGTCACCTATG
CGGCCTTGTTGCACACCTATCCACAGTCCGCGCATGCGCATTACCTGCTCGGCCTGTTCCTGCGCAACAACGCGCAGGCC
GCCGAGCATCTGCAGCAATCGGTGCAGTGCCTGCAGCAGGCCTGCACGCTGGCACCGGACAACCTGCACGCCCGCGAGGC
GCTGGGCACCGGGCTCTACCTGTTGGGCGAGCAGGCGCAGGCGCAAACGGTGTATCGCGACTGGCTGGCGCTTGAGCCGG
GCAACGCAGTGGCGACGCATATGCTGGCGGCCTGTGGTGGTGCCGAACCGCCGCCGCGTGCTGGCGATACCTATGTGCGT
GAACTGTTCGATGGCTTTGCCGACAGTTTCGACGAACAGTTGCTGCATCACCTGGAGTACCGCGCGCCGCACCGGCTGAC
CGAGGCATTGGCGGCCTGCCTTGCGCCACCGCATGCAGGCTTGCGCATGCTCGATGCCGGCTGCGGCACCGGGCTGTGTG
CGCCGTTGTGGCGCCCGTATGCACGTGAACTGGTGGGTGTGGACCTGTCGCCGGGCATGGTCGCCAAGGCACGCCAACGC
GGTGGCTACGATCGCCTCGACGTGGCCGAACTCACTGCATACCTGCACGCGCAGCACGCGCAGTGGGACGTGATCGGCTC
GGCCGACACGTTGGTGTACTTCGGTGCGCTGCAGCCGGTGCTCGCTGCCGCTGCTGGCGCGCTCACGCCAGGGGGCGTGC
TGGGCTTCACGGTCGAAGCGCTGGACGCGCGGAGCGACCGGGTCGAACTCGATGCCAGCGGGCGCTATCGGCACAGCCAT
GCGCATGTGCGCGCCGCATTGCGAGGCGCTGGTCTGCAGCCGATCGCGTTGGAATTGGACGTGCTGCGCAGCGAACGCGG
CCAGCCGGTGCATGGCTGGGTCGTGACCGCGCGCACGCCTGGGTCGGCCTGA

Upstream 100 bases:

>100_bases
ACGGTCGTGGTGTTGGCTGCGCGTTGCAGGCGTGACGCCGTGCCGCTCCGCGCTCAGGTTCGTACCCGCACCACCGGTTG
CCGTGTCTTTGGAGAAGCTC

Downstream 100 bases:

>100_bases
GACGAAATGTCGGCTTTGCCGCACGCACGCATGTGAGCATGTGCGTGACGGTTGCCGTGCCCGAGCCGCCTGCCGTTGCA
CGTGCGGGTACGCAACACAG

Product: hypothetical protein

Products: NA

Alternate protein names: TPR Repeat-Containing Protein; Methyltransferase; 3-Demethylubiquinone-9 3-Methyltransferase; Methyltransferase Protein; Tetratricopeptide TPR_2 Repeat Protein; SAM-Dependent Methyltransferase; Peptidase S1 And S6 Chymotrypsin/Hap; SAM-Dependent Methyltransferases; Tetratricopeptide Repeat-Containing Protein; Protein With TPR Motifs; TPR Repeat-Containing Methyltransferase; Two Domain Fusion Protein; Methyltransferase Domain Family; Methyltransferase Domain Family Protein; TPR Domain-Containing Protein

Number of amino acids: Translated: 443; Mature: 443

Protein sequence:

>443_residues
MQTATQPHPEALQQAIAAHRSGRLEHAAQLYTQLLDDQPGHADALHYQGILLHQRGNSAAAVASITQALTLAPAQPDACN
NLGNVHRECGRLRDAERCYRRALALAPAHADALANLAAVLEAQRRGEEAFVTYAALLHTYPQSAHAHYLLGLFLRNNAQA
AEHLQQSVQCLQQACTLAPDNLHAREALGTGLYLLGEQAQAQTVYRDWLALEPGNAVATHMLAACGGAEPPPRAGDTYVR
ELFDGFADSFDEQLLHHLEYRAPHRLTEALAACLAPPHAGLRMLDAGCGTGLCAPLWRPYARELVGVDLSPGMVAKARQR
GGYDRLDVAELTAYLHAQHAQWDVIGSADTLVYFGALQPVLAAAAGALTPGGVLGFTVEALDARSDRVELDASGRYRHSH
AHVRAALRGAGLQPIALELDVLRSERGQPVHGWVVTARTPGSA

Sequences:

>Translated_443_residues
MQTATQPHPEALQQAIAAHRSGRLEHAAQLYTQLLDDQPGHADALHYQGILLHQRGNSAAAVASITQALTLAPAQPDACN
NLGNVHRECGRLRDAERCYRRALALAPAHADALANLAAVLEAQRRGEEAFVTYAALLHTYPQSAHAHYLLGLFLRNNAQA
AEHLQQSVQCLQQACTLAPDNLHAREALGTGLYLLGEQAQAQTVYRDWLALEPGNAVATHMLAACGGAEPPPRAGDTYVR
ELFDGFADSFDEQLLHHLEYRAPHRLTEALAACLAPPHAGLRMLDAGCGTGLCAPLWRPYARELVGVDLSPGMVAKARQR
GGYDRLDVAELTAYLHAQHAQWDVIGSADTLVYFGALQPVLAAAAGALTPGGVLGFTVEALDARSDRVELDASGRYRHSH
AHVRAALRGAGLQPIALELDVLRSERGQPVHGWVVTARTPGSA
>Mature_443_residues
MQTATQPHPEALQQAIAAHRSGRLEHAAQLYTQLLDDQPGHADALHYQGILLHQRGNSAAAVASITQALTLAPAQPDACN
NLGNVHRECGRLRDAERCYRRALALAPAHADALANLAAVLEAQRRGEEAFVTYAALLHTYPQSAHAHYLLGLFLRNNAQA
AEHLQQSVQCLQQACTLAPDNLHAREALGTGLYLLGEQAQAQTVYRDWLALEPGNAVATHMLAACGGAEPPPRAGDTYVR
ELFDGFADSFDEQLLHHLEYRAPHRLTEALAACLAPPHAGLRMLDAGCGTGLCAPLWRPYARELVGVDLSPGMVAKARQR
GGYDRLDVAELTAYLHAQHAQWDVIGSADTLVYFGALQPVLAAAAGALTPGGVLGFTVEALDARSDRVELDASGRYRHSH
AHVRAALRGAGLQPIALELDVLRSERGQPVHGWVVTARTPGSA

Specific function: Bioc Is Involved In An Early, But Chemically Unexplored, Step In The Conversion Of Pimelic Acid To Biotin. [C]

COG id: COG4976

COG function: function code R; Predicted methyltransferase (contains TPR repeat)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI32307148, Length=263, Percent_Identity=28.5171102661597, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI32307150, Length=263, Percent_Identity=28.5171102661597, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI115532692, Length=269, Percent_Identity=27.5092936802974, Blast_Score=82, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI115532690, Length=269, Percent_Identity=27.5092936802974, Blast_Score=81, Evalue=9e-16,
Organism=Drosophila melanogaster, GI17647755, Length=276, Percent_Identity=26.4492753623188, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24585827, Length=276, Percent_Identity=26.4492753623188, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24585829, Length=276, Percent_Identity=26.4492753623188, Blast_Score=76, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 47515; Mature: 47515

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS50005 TPR L=RR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTATQPHPEALQQAIAAHRSGRLEHAAQLYTQLLDDQPGHADALHYQGILLHQRGNSAA
CCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCEEECCEEEEECCCCHH
AVASITQALTLAPAQPDACNNLGNVHRECGRLRDAERCYRRALALAPAHADALANLAAVL
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHH
EAQRRGEEAFVTYAALLHTYPQSAHAHYLLGLFLRNNAQAAEHLQQSVQCLQQACTLAPD
HHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCC
NLHAREALGTGLYLLGEQAQAQTVYRDWLALEPGNAVATHMLAACGGAEPPPRAGDTYVR
CCHHHHHHCCCCEEECCHHHHHHHHHHHHEECCCCHHHHHHHHHHCCCCCCCCCCHHHHH
ELFDGFADSFDEQLLHHLEYRAPHRLTEALAACLAPPHAGLRMLDAGCGTGLCAPLWRPY
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCEEHHCCCCCCCHHHHHHHH
ARELVGVDLSPGMVAKARQRGGYDRLDVAELTAYLHAQHAQWDVIGSADTLVYFGALQPV
HHHHHCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHH
LAAAAGALTPGGVLGFTVEALDARSDRVELDASGRYRHSHAHVRAALRGAGLQPIALELD
HHHHHCCCCCCCHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHCCCCCCHHHHHH
VLRSERGQPVHGWVVTARTPGSA
HHHCCCCCCEEEEEEEECCCCCC
>Mature Secondary Structure
MQTATQPHPEALQQAIAAHRSGRLEHAAQLYTQLLDDQPGHADALHYQGILLHQRGNSAA
CCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCEEECCEEEEECCCCHH
AVASITQALTLAPAQPDACNNLGNVHRECGRLRDAERCYRRALALAPAHADALANLAAVL
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHH
EAQRRGEEAFVTYAALLHTYPQSAHAHYLLGLFLRNNAQAAEHLQQSVQCLQQACTLAPD
HHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCC
NLHAREALGTGLYLLGEQAQAQTVYRDWLALEPGNAVATHMLAACGGAEPPPRAGDTYVR
CCHHHHHHCCCCEEECCHHHHHHHHHHHHEECCCCHHHHHHHHHHCCCCCCCCCCHHHHH
ELFDGFADSFDEQLLHHLEYRAPHRLTEALAACLAPPHAGLRMLDAGCGTGLCAPLWRPY
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCEEHHCCCCCCCHHHHHHHH
ARELVGVDLSPGMVAKARQRGGYDRLDVAELTAYLHAQHAQWDVIGSADTLVYFGALQPV
HHHHHCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHH
LAAAAGALTPGGVLGFTVEALDARSDRVELDASGRYRHSHAHVRAALRGAGLQPIALELD
HHHHHCCCCCCCHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHCCCCCCHHHHHH
VLRSERGQPVHGWVVTARTPGSA
HHHCCCCCCEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA