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The map label for this gene is fhuA [H]

Identifier: 21244779

GI number: 21244779

Start: 4758091

End: 4760271

Strand: Reverse

Name: fhuA [H]

Synonym: XAC4062

Alternate gene names: 21244779

Gene position: 4760271-4758091 (Counterclockwise)

Preceding gene: 21244780

Following gene: 21244778

Centisome position: 91.98

GC content: 63.59

Gene sequence:

>2181_bases
ATGACGTGCACGCAAGCCACGCTGCTGTCCTTGTCGATTGCCGCCGCATTGGGCTGCATCGGCGCCGCACGCGCGCAGCA
GACAGCCACGGTGCAAGCCACCGAGGCGACCACGCTGGACCAGGTCGTCGTGAGCGGCCGCCTGCGTTCGCTGGAGCAAT
TCACCCCGACCGGCAGCCGGCTCAATCTGTCCGCGCGCGAGACGCCCGGTACGCTGGATGCGATCAACGCCGCCGCCATC
GAAGCACGCGGGCTACGCAGCGTGGAGAAGGCAGCCGAGAGTTTGCCAGGCATCAACACTGGCGGCTCGCCGGGAAATCC
GGCGACCTTCTCGATGCGCGGCTTCACCGACGGGCAGATCACCATCCTGCACAACGGCCTGTATCTGGGACCGTCGAACA
TGACCAACCGGCCGCAGAATACCTTCAACCTGCAATCGGTCGAAGTGTTGAAAGGCCCGGCGTCGGTGATCTATGGCCAG
GGCGCGGTGGGCGGCGCGGTCAATGTGACCAACAAGGCGCCGACCTTCGGCCCTGCGCAATACGAACTGCTGCTGGGCGC
GTCCAGCTACGGCGGCCGGGTATTCGGCGTCGGTGCCGGCGGCGGCATCAATGATGATTGGGCGTATCGCGCCGACATCA
GCCAGGTGTCGTCTGATGGCTATGTGCACGGCGCCGATTCCAGCGCGATCAACGCCACCGTGTCGCTGCTGTGGCACCCG
CGCGAAGACATCAGCGCGCAATTTTCGCTGGATTACGCAAAAGACCAGCCCTCGACCTACTTCGGTACCCCGCTGTTGCC
GGCCGCTGCGGCACGCACGCCCATCAACGGCATCCTGCGCGCGCCCAATGGCGAAGTGGTGGATGCCGCCACGCGCCGCA
CCAACTACAACGTGGCCGATGCCAGCATCGACTCGCGTCAGCTGTGGCCGCAGGCCTATCTCAAGTGGAAGGTCACCGAT
GCCATCACCGTGCAGAACATGGCCTATTACTTCCATGCCGATCGGCGCTGGATCAATGCGGAGAACTACACCTACAACCC
GCAGAGCGGGCGCATCGAGCGTGATCGCTTCTTCGTGTATCACGAGCAGGCGCTGTGGGGGAATCAGACCAGCGCGACCT
TCGACCAGCGCATCGCAGGGCTGAAGAACCGGCTTGTGGTGGGGCTGGATTACAGTCGCCTGGACTTCGTCAGGAACCGC
GGCTTCCCCGATGGCGACAGCGTGGCGGTGGACGCACGCGGACCAAGCGGTGAATTCGGCGAACGCGTGCGCCGACGCAG
CCCCACCACCTGGACCAATGCCGCGCTGTTTTTCGAAGATGCGCTGGATGTCACCGACAAGGCAAAACTGGTACTCGGCG
GGCGCTACGAATATCTCGATCTGGATCGCAAGAACTTCGGTCCGGATGGTGGGTTTCAGGCGGCATCGAGTTTCTCACGC
ACCTACCGCCCGGCCAATGGCCGTCTCGGTCTGGTCTACGCGCTCACCCCGAACATCACCCCGTACGCCTCTTACACCAC
CGCCACCGACCCGGTCGGTTCCAATATCTTCATCGTCAATGCGGGGCAGGATTTTGCGTTGAGCAAATCGCGGCAGGCGG
AAGTCGGCGTCAAGGCCGCCACGGCCGATCAACGCCTGAGCGGCACGCTGGCGGTCTATGACATCAAACGCAACAACATC
CTGGCGCTGACGGCCCAGGACGCGCTCAGCAACATCGGGCGGCAAACCTCGCGCGGGTTCGAACTCAGCGTCGATGCGCA
GCTGACCTCGCAGTGGAGCGCAAATGCCAACTACGCCTACGTCGATGCCGAGTACGCGCAATTCATCGACAGCAATAGCG
GCCTGGACGCCTCCGGCAACCGCCCCACCAATGTACCCAAGTCGCTGTTCAATGCCTGGACCAGCGTGAGAAACGTCGCC
GGCCTGCCGCTGGAGCTGGGCGCCTCGGTGCGCCATGTCGGAACGCGCTACGGCAACCTCGCCAACACGCTGCGTCTGGA
GTCGTACACCTTGACCGGTGCGTACGCCACCTACGATATGAATTCCGAGGTGTCGCTATCGCTGCACGCGGACAATCTGT
TCAACACGCACTACGTGCAATGGGCGGACGTGTTCTATCCCGGGCAGGTCATCCTGGGCTTGCCACGGACGGTGGAGCTG
AGCCTGCATGCACGTTTCTGA

Upstream 100 bases:

>100_bases
GGCCGCCATTCGCGCCTACCTCTCGCACCGTTTCGCCGTTGCACGGCAGCGCTGAGGTACGCGCGCTCCGGCCTTCCACC
TGCCTTTCTGGAGAACGCAC

Downstream 100 bases:

>100_bases
CCGGCTGGCACGGCCCAGGCCGAAGATATTCTGGGTCGCCTGGTTGCATCGCTGGACGGGCGTGGCGTTCTGCCTGATGT
TCGCAGTGTGGTTCGCCAGC

Product: TonB-dependent receptor

Products: NA

Alternate protein names: Ferric hydroxamate receptor; Ferric hydroxamate uptake [H]

Number of amino acids: Translated: 726; Mature: 725

Protein sequence:

>726_residues
MTCTQATLLSLSIAAALGCIGAARAQQTATVQATEATTLDQVVVSGRLRSLEQFTPTGSRLNLSARETPGTLDAINAAAI
EARGLRSVEKAAESLPGINTGGSPGNPATFSMRGFTDGQITILHNGLYLGPSNMTNRPQNTFNLQSVEVLKGPASVIYGQ
GAVGGAVNVTNKAPTFGPAQYELLLGASSYGGRVFGVGAGGGINDDWAYRADISQVSSDGYVHGADSSAINATVSLLWHP
REDISAQFSLDYAKDQPSTYFGTPLLPAAAARTPINGILRAPNGEVVDAATRRTNYNVADASIDSRQLWPQAYLKWKVTD
AITVQNMAYYFHADRRWINAENYTYNPQSGRIERDRFFVYHEQALWGNQTSATFDQRIAGLKNRLVVGLDYSRLDFVRNR
GFPDGDSVAVDARGPSGEFGERVRRRSPTTWTNAALFFEDALDVTDKAKLVLGGRYEYLDLDRKNFGPDGGFQAASSFSR
TYRPANGRLGLVYALTPNITPYASYTTATDPVGSNIFIVNAGQDFALSKSRQAEVGVKAATADQRLSGTLAVYDIKRNNI
LALTAQDALSNIGRQTSRGFELSVDAQLTSQWSANANYAYVDAEYAQFIDSNSGLDASGNRPTNVPKSLFNAWTSVRNVA
GLPLELGASVRHVGTRYGNLANTLRLESYTLTGAYATYDMNSEVSLSLHADNLFNTHYVQWADVFYPGQVILGLPRTVEL
SLHARF

Sequences:

>Translated_726_residues
MTCTQATLLSLSIAAALGCIGAARAQQTATVQATEATTLDQVVVSGRLRSLEQFTPTGSRLNLSARETPGTLDAINAAAI
EARGLRSVEKAAESLPGINTGGSPGNPATFSMRGFTDGQITILHNGLYLGPSNMTNRPQNTFNLQSVEVLKGPASVIYGQ
GAVGGAVNVTNKAPTFGPAQYELLLGASSYGGRVFGVGAGGGINDDWAYRADISQVSSDGYVHGADSSAINATVSLLWHP
REDISAQFSLDYAKDQPSTYFGTPLLPAAAARTPINGILRAPNGEVVDAATRRTNYNVADASIDSRQLWPQAYLKWKVTD
AITVQNMAYYFHADRRWINAENYTYNPQSGRIERDRFFVYHEQALWGNQTSATFDQRIAGLKNRLVVGLDYSRLDFVRNR
GFPDGDSVAVDARGPSGEFGERVRRRSPTTWTNAALFFEDALDVTDKAKLVLGGRYEYLDLDRKNFGPDGGFQAASSFSR
TYRPANGRLGLVYALTPNITPYASYTTATDPVGSNIFIVNAGQDFALSKSRQAEVGVKAATADQRLSGTLAVYDIKRNNI
LALTAQDALSNIGRQTSRGFELSVDAQLTSQWSANANYAYVDAEYAQFIDSNSGLDASGNRPTNVPKSLFNAWTSVRNVA
GLPLELGASVRHVGTRYGNLANTLRLESYTLTGAYATYDMNSEVSLSLHADNLFNTHYVQWADVFYPGQVILGLPRTVEL
SLHARF
>Mature_725_residues
TCTQATLLSLSIAAALGCIGAARAQQTATVQATEATTLDQVVVSGRLRSLEQFTPTGSRLNLSARETPGTLDAINAAAIE
ARGLRSVEKAAESLPGINTGGSPGNPATFSMRGFTDGQITILHNGLYLGPSNMTNRPQNTFNLQSVEVLKGPASVIYGQG
AVGGAVNVTNKAPTFGPAQYELLLGASSYGGRVFGVGAGGGINDDWAYRADISQVSSDGYVHGADSSAINATVSLLWHPR
EDISAQFSLDYAKDQPSTYFGTPLLPAAAARTPINGILRAPNGEVVDAATRRTNYNVADASIDSRQLWPQAYLKWKVTDA
ITVQNMAYYFHADRRWINAENYTYNPQSGRIERDRFFVYHEQALWGNQTSATFDQRIAGLKNRLVVGLDYSRLDFVRNRG
FPDGDSVAVDARGPSGEFGERVRRRSPTTWTNAALFFEDALDVTDKAKLVLGGRYEYLDLDRKNFGPDGGFQAASSFSRT
YRPANGRLGLVYALTPNITPYASYTTATDPVGSNIFIVNAGQDFALSKSRQAEVGVKAATADQRLSGTLAVYDIKRNNIL
ALTAQDALSNIGRQTSRGFELSVDAQLTSQWSANANYAYVDAEYAQFIDSNSGLDASGNRPTNVPKSLFNAWTSVRNVAG
LPLELGASVRHVGTRYGNLANTLRLESYTLTGAYATYDMNSEVSLSLHADNLFNTHYVQWADVFYPGQVILGLPRTVELS
LHARF

Specific function: This receptor binds the ferrichrome-iron ligand. It interacts with the tonB protein, which is responsible for energy coupling of the ferrichrome-promoted iron transport system. Acts as a receptor for bacteriophage T5 as well as T1, phi80 and colicin M. Bi

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1786344, Length=720, Percent_Identity=24.7222222222222, Blast_Score=147, Evalue=3e-36,
Organism=Escherichia coli, GI1787723, Length=639, Percent_Identity=23.4741784037559, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1787024, Length=257, Percent_Identity=26.0700389105058, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1787344, Length=375, Percent_Identity=22.6666666666667, Blast_Score=63, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 78456; Mature: 78325

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: PS01156 TONB_DEPENDENT_REC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTCTQATLLSLSIAAALGCIGAARAQQTATVQATEATTLDQVVVSGRLRSLEQFTPTGSR
CCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCE
LNLSARETPGTLDAINAAAIEARGLRSVEKAAESLPGINTGGSPGNPATFSMRGFTDGQI
EEEECCCCCCCHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCEE
TILHNGLYLGPSNMTNRPQNTFNLQSVEVLKGPASVIYGQGAVGGAVNVTNKAPTFGPAQ
EEEECCEEECCCCCCCCCCCCCCCEEEEEECCCCCEEEECCCCCCEEEECCCCCCCCCCE
YELLLGASSYGGRVFGVGAGGGINDDWAYRADISQVSSDGYVHGADSSAINATVSLLWHP
EEEEEECCCCCCEEEEEECCCCCCCCCEEECCHHHHCCCCEEECCCCCCCEEEEEEEECC
REDISAQFSLDYAKDQPSTYFGTPLLPAAAARTPINGILRAPNGEVVDAATRRTNYNVAD
CCCCCEEEEEEECCCCCCCCCCCCCCCHHHHCCCCCCEEECCCCCEEEEEHHCCCCCEEC
ASIDSRQLWPQAYLKWKVTDAITVQNMAYYFHADRRWINAENYTYNPQSGRIERDRFFVY
CCCCCHHCCCCCEEEEEEEEEEEEEEEEEEEECCCEEECCCCCEECCCCCCEECCEEEEE
HEQALWGNQTSATFDQRIAGLKNRLVVGLDYSRLDFVRNRGFPDGDSVAVDARGPSGEFG
EEHHHCCCCCCHHHHHHHHCCCCCEEEEECHHHHHHHHHCCCCCCCCEEEECCCCCCHHH
ERVRRRSPTTWTNAALFFEDALDVTDKAKLVLGGRYEYLDLDRKNFGPDGGFQAASSFSR
HHHHHCCCCCCCCEEEEEECCCCCCCCCEEEECCCEEEEECCCCCCCCCCCHHHHHHHHH
TYRPANGRLGLVYALTPNITPYASYTTATDPVGSNIFIVNAGQDFALSKSRQAEVGVKAA
HCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCEEEE
TADQRLSGTLAVYDIKRNNILALTAQDALSNIGRQTSRGFELSVDAQLTSQWSANANYAY
CCCCCCCCEEEEEEECCCCEEEEECHHHHHHCCHHCCCCEEEEEEEEECCCCCCCCCEEE
VDAEYAQFIDSNSGLDASGNRPTNVPKSLFNAWTSVRNVAGLPLELGASVRHVGTRYGNL
EEHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHCCC
ANTLRLESYTLTGAYATYDMNSEVSLSLHADNLFNTHYVQWADVFYPGQVILGLPRTVEL
HHEEEEEEEEEEEEEEEEECCCCEEEEEECCCCCCCEEEEEEEEEECCEEEEECCCEEEE
SLHARF
EEEECC
>Mature Secondary Structure 
TCTQATLLSLSIAAALGCIGAARAQQTATVQATEATTLDQVVVSGRLRSLEQFTPTGSR
CCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCE
LNLSARETPGTLDAINAAAIEARGLRSVEKAAESLPGINTGGSPGNPATFSMRGFTDGQI
EEEECCCCCCCHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCEE
TILHNGLYLGPSNMTNRPQNTFNLQSVEVLKGPASVIYGQGAVGGAVNVTNKAPTFGPAQ
EEEECCEEECCCCCCCCCCCCCCCEEEEEECCCCCEEEECCCCCCEEEECCCCCCCCCCE
YELLLGASSYGGRVFGVGAGGGINDDWAYRADISQVSSDGYVHGADSSAINATVSLLWHP
EEEEEECCCCCCEEEEEECCCCCCCCCEEECCHHHHCCCCEEECCCCCCCEEEEEEEECC
REDISAQFSLDYAKDQPSTYFGTPLLPAAAARTPINGILRAPNGEVVDAATRRTNYNVAD
CCCCCEEEEEEECCCCCCCCCCCCCCCHHHHCCCCCCEEECCCCCEEEEEHHCCCCCEEC
ASIDSRQLWPQAYLKWKVTDAITVQNMAYYFHADRRWINAENYTYNPQSGRIERDRFFVY
CCCCCHHCCCCCEEEEEEEEEEEEEEEEEEEECCCEEECCCCCEECCCCCCEECCEEEEE
HEQALWGNQTSATFDQRIAGLKNRLVVGLDYSRLDFVRNRGFPDGDSVAVDARGPSGEFG
EEHHHCCCCCCHHHHHHHHCCCCCEEEEECHHHHHHHHHCCCCCCCCEEEECCCCCCHHH
ERVRRRSPTTWTNAALFFEDALDVTDKAKLVLGGRYEYLDLDRKNFGPDGGFQAASSFSR
HHHHHCCCCCCCCEEEEEECCCCCCCCCEEEECCCEEEEECCCCCCCCCCCHHHHHHHHH
TYRPANGRLGLVYALTPNITPYASYTTATDPVGSNIFIVNAGQDFALSKSRQAEVGVKAA
HCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCEEEE
TADQRLSGTLAVYDIKRNNILALTAQDALSNIGRQTSRGFELSVDAQLTSQWSANANYAY
CCCCCCCCEEEEEEECCCCEEEEECHHHHHHCCHHCCCCEEEEEEEEECCCCCCCCCEEE
VDAEYAQFIDSNSGLDASGNRPTNVPKSLFNAWTSVRNVAGLPLELGASVRHVGTRYGNL
EEHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHCCC
ANTLRLESYTLTGAYATYDMNSEVSLSLHADNLFNTHYVQWADVFYPGQVILGLPRTVEL
HHEEEEEEEEEEEEEEEEECCCCEEEEEECCCCCCCEEEEEEEEEECCEEEEECCCEEEE
SLHARF
EEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3079747; 8202364; 9278503; 2823072; 7515827; 8617231; 9856937; 9865695; 10850805 [H]