Click here to switch to the map view.

The map label for this gene is blc [H]

Identifier: 21244675

GI number: 21244675

Start: 4652191

End: 4652748

Strand: Direct

Name: blc [H]

Synonym: XAC3956

Alternate gene names: 21244675

Gene position: 4652191-4652748 (Clockwise)

Preceding gene: 21244674

Following gene: 21244677

Centisome position: 89.89

GC content: 62.54

Gene sequence:

>558_bases
ATGGCGCGACACGTACAACAGGCGCCACTCCATTGTGCTGAGGCCTGTATGAGCCACCATCCCGAACTCGCCACTGTCCC
TTCGCTGGATCTGAATCGCTACCTAGGCACGTGGTACGAAATCGCCCGCCTGCCGACCCGCTTCGAGGATGCGGACTGCA
CCGATGTGTCGGCGCACTACACCCTGGAAGACGACGGCAGCGTGCGCGTCCAGAATCGCTGTTTTACCGCGGAAGGCGAG
CTGGAAGAAGCGATCGGCCAGGCGCGCGCCATCGACGACACGCACAGCCGGCTGGAAGTGACCTTCCTACCCGAGGGTCT
GCGCTGGATCCCTTTTACCAAAGGCGACTACTGGGTGATGCGCATCGATGCCGATTACACCGCCGCACTGGTCGGCAGCC
CGGATCGCAAATACTTATGGCTACTTGCACGGTTGCCGCAGCTGGACGAAAACATCGCCCAGGCCTATCTGGCGCATGCA
CGCGAACAAGGCTTCGACCTAGCGCCGCTGATCCACACCCCGCACACCGGGCGGCTGACCGAGCAACCGCTTCCGTAG

Upstream 100 bases:

>100_bases
GAGCGGCATCGTGCCAACGCCAATACGCACCGAGCCGATGCTCTCAGGCACGCCCGTCCTTGCTGCACGGCCGCTCGCGC
CGCATCCCAACATGCATTTC

Downstream 100 bases:

>100_bases
GGGATTCCGACTAGTTGGTACGTCGTCAGGCCGGCGACCACAGCGCCGCTGCGCCTCACTACAACGGTAGCGGCGTCGAT
GCACTGACCAACGCACGACA

Product: outer membrane lipoprotein Blc

Products: NA

Alternate protein names: Protein vlp [H]

Number of amino acids: Translated: 185; Mature: 184

Protein sequence:

>185_residues
MARHVQQAPLHCAEACMSHHPELATVPSLDLNRYLGTWYEIARLPTRFEDADCTDVSAHYTLEDDGSVRVQNRCFTAEGE
LEEAIGQARAIDDTHSRLEVTFLPEGLRWIPFTKGDYWVMRIDADYTAALVGSPDRKYLWLLARLPQLDENIAQAYLAHA
REQGFDLAPLIHTPHTGRLTEQPLP

Sequences:

>Translated_185_residues
MARHVQQAPLHCAEACMSHHPELATVPSLDLNRYLGTWYEIARLPTRFEDADCTDVSAHYTLEDDGSVRVQNRCFTAEGE
LEEAIGQARAIDDTHSRLEVTFLPEGLRWIPFTKGDYWVMRIDADYTAALVGSPDRKYLWLLARLPQLDENIAQAYLAHA
REQGFDLAPLIHTPHTGRLTEQPLP
>Mature_184_residues
ARHVQQAPLHCAEACMSHHPELATVPSLDLNRYLGTWYEIARLPTRFEDADCTDVSAHYTLEDDGSVRVQNRCFTAEGEL
EEAIGQARAIDDTHSRLEVTFLPEGLRWIPFTKGDYWVMRIDADYTAALVGSPDRKYLWLLARLPQLDENIAQAYLAHAR
EQGFDLAPLIHTPHTGRLTEQPLP

Specific function: Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids [H]

COG id: COG3040

COG function: function code M; Bacterial lipocalin

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the calycin superfamily. Lipocalin family [H]

Homologues:

Organism=Homo sapiens, GI4502163, Length=128, Percent_Identity=31.25, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1790592, Length=167, Percent_Identity=38.3233532934132, Blast_Score=101, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012674
- InterPro:   IPR011038
- InterPro:   IPR013208
- InterPro:   IPR022271
- InterPro:   IPR002446
- InterPro:   IPR022272 [H]

Pfam domain/function: PF08212 Lipocalin_2 [H]

EC number: NA

Molecular weight: Translated: 20994; Mature: 20863

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS00213 LIPOCALIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARHVQQAPLHCAEACMSHHPELATVPSLDLNRYLGTWYEIARLPTRFEDADCTDVSAHY
CCCCCHHCHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEE
TLEDDGSVRVQNRCFTAEGELEEAIGQARAIDDTHSRLEVTFLPEGLRWIPFTKGDYWVM
EECCCCCEEEECEEECCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEECCCCEEEE
RIDADYTAALVGSPDRKYLWLLARLPQLDENIAQAYLAHAREQGFDLAPLIHTPHTGRLT
EECCCCEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCC
EQPLP
CCCCC
>Mature Secondary Structure 
ARHVQQAPLHCAEACMSHHPELATVPSLDLNRYLGTWYEIARLPTRFEDADCTDVSAHY
CCCCHHCHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEE
TLEDDGSVRVQNRCFTAEGELEEAIGQARAIDDTHSRLEVTFLPEGLRWIPFTKGDYWVM
EECCCCCEEEECEEECCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEECCCCEEEE
RIDADYTAALVGSPDRKYLWLLARLPQLDENIAQAYLAHAREQGFDLAPLIHTPHTGRLT
EECCCCEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCC
EQPLP
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8514410; 10952301 [H]