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The map label for this gene is nagJ [H]

Identifier: 21244647

GI number: 21244647

Start: 4619746

End: 4621731

Strand: Reverse

Name: nagJ [H]

Synonym: XAC3928

Alternate gene names: 21244647

Gene position: 4621731-4619746 (Counterclockwise)

Preceding gene: 21244648

Following gene: 21244645

Centisome position: 89.3

GC content: 66.82

Gene sequence:

>1986_bases
ATGAAGCGACGCAACAGCAAGCCGGGCGTGCGCCTGCTTTCGGTCTTGGTGGCGCTGGGCCTGGCTGCCCCTGCGTTGGC
GCAATCGGTCACCGAACCGGTCACCCAGCCGGCGATCTATCCGACTCCGGTCTCGATCACGCTGGATGGTGCCACCATCA
CCTTGGGCCGCTCGGCGGTGCTGGTGGTCGCCCCTGGCGCGGACAAGGCCACGGTGGCGCTGGTGCGCAGCATTCTCGAT
GGCGCCGGCGTCACCAAGATTGCGACCGCCACACGCCTGCCTGCCACCCTGGACCGCCCGTACATCGTGCTCGGCACCGG
CGATGCGGCAGTGGTGCGCGATGCGCTGACGCGCAGCAAGGCGACGCAGGACACCCATAAGGAAGGCTACACGCTGGCCA
GCGTTGCGCGCGATCGCGGCAGCCTGATCACGCTGGCCGGCCACGATGACGATGGCCTGTTTCATGCGGCGCAGACGCTG
CGGCAGCTGGTCGAGCGGCCGGCCATCCCGACGCTGACGATCCAGGATTACCCGTCCATGCCGATCCGCGGCACCATCGA
AGGCTTCTACGGCGCGCCGTGGTCGATGAGCGATCGCAGCAAGCACATCGATTTCCTCGCCCGCACCAAGGCCAATACCT
TCATTTACAGCCCGAAGGACGACCCTTACGCGCGCGATCGCTGGCGCGAGGCGTACCCGAAGGCGACCTTGAAGGCGCTC
GGCCAACTGGCCGCCACCGCCAAGCGTAATCACGTCGATTTCGTCTATGCGATTTCGCCTGGCCCCACGGTGTGCTTCTC
CGATCCGGCCGATGCCAAGGCCTTGTTGCGCAAGTTCGATGCGTTCCGCGCGCTGGGCGTGCGCAGCTTCTACGTGGCGC
TGGACGACATCGAATACACCAAATGGAATTGCGAACGCGACAAGACCACCTTCGGCGAATCCGGCGCGCAGGCGGCCGGT
ATCGCGCAGTCGCATCTGCTCAATCTGGTGCAGGCGGATCTGGTCGCGCGCCACGATGCGGCCTCCGAACTCATCATGGT
GCCGACCGAGTACTACGACGCCAAAGAGAGCCCGTACAAGGAAGCGCTGCGCAAGCATCTGGACCCGAAGATCGTGGTGC
AGTGGACCGGCACCGACGTGGTGCCGCCGGCCATTTCCATCCCCGATGCGCGCGCGGCCACCAAGGCGTTCGGCCGCAGG
ACGCTGCTGTGGGACAACTACCCGGTCAACGACTTCGAAACCTCGGCCGGGCGCCTGCTGATGGCGCCGTATGCGCGGCG
CGAGGCGGGTCTGTCGGCCGAGTTGTCGGGCATCGTCTCCAACCCGATGAACCAGGAAGTGCCCAGCCGCGTCGCGGTGA
TGGGTGTGGCCGCGTTCGCCTGGAACGACAAGGACTACGACGCGCAACGCACCTGGCACGCGGCGGCGCGCGATCTTGCC
GGCGGCGATGCGCGTGTCGCTGCGGCCCTGCTGACCTTCTTCGACACCCAGCACTTGGCGCCAACCTTTGGCAGCCAGCC
GTGGCAGGAACAGGCGCCACGCTTGAAGGCCGTGCTCGATCATGTACGCGAGGCAGTCGCGCTTGGCGATGCGGCAACAC
GCACGCAGGCGATTGCCGAACTGGCACGCACTGCCGACGAAATGGCTGCGGCACCGCAGATCATCCGCGACGGCGTGGTC
GACAAGGGCTTTGCCGAGCAATCGCGCCCCTGGCTGGAGGCAATGGAAGGTTGGGGCCATGCGCTGCAGAAGACGGCAGC
CGGGCTGGATGCGGCCAATCGCGGCGACACGCAGACGCCCGCGTTGTTTGCCGAGGCGGCTGCGATCGCCGCCGTCGCGA
GCCAGATCCCATCGATTCCCGGCGCCACGCGCTTCGGCGGCCCGGTCAAGATCGCCGACGGCGTGCTGGACCGCTTCATC
GCGCAGGCACCGCACTTGATCGCCTATCGCCAGGCGGCAGTGACTGATTCGGCAGCAGCAAAGTGA

Upstream 100 bases:

>100_bases
ATCCAGGTATTGGCCAAATTGAAATTCCGGCCGCGCTTGTCGCCGTCGCGCGACTTGCCTACCCTAGGGCGTAATACCAT
TCCAATACCGGAGTTCGAGA

Downstream 100 bases:

>100_bases
TGGGGTAGTGCAGAAACACCGCGGCGCGCATGGGGAATGGTTCGCGTCGCGGTGCATGCAAACACGACAGCGCCATTGCC
ATCTGCATCGCAGCACGTGG

Product: hypothetical protein

Products: NA

Alternate protein names: Beta-N-acetylhexosaminidase; Beta-hexosaminidase; GH84; Hexosaminidase B; N-acetyl-beta-glucosaminidase [H]

Number of amino acids: Translated: 661; Mature: 661

Protein sequence:

>661_residues
MKRRNSKPGVRLLSVLVALGLAAPALAQSVTEPVTQPAIYPTPVSITLDGATITLGRSAVLVVAPGADKATVALVRSILD
GAGVTKIATATRLPATLDRPYIVLGTGDAAVVRDALTRSKATQDTHKEGYTLASVARDRGSLITLAGHDDDGLFHAAQTL
RQLVERPAIPTLTIQDYPSMPIRGTIEGFYGAPWSMSDRSKHIDFLARTKANTFIYSPKDDPYARDRWREAYPKATLKAL
GQLAATAKRNHVDFVYAISPGPTVCFSDPADAKALLRKFDAFRALGVRSFYVALDDIEYTKWNCERDKTTFGESGAQAAG
IAQSHLLNLVQADLVARHDAASELIMVPTEYYDAKESPYKEALRKHLDPKIVVQWTGTDVVPPAISIPDARAATKAFGRR
TLLWDNYPVNDFETSAGRLLMAPYARREAGLSAELSGIVSNPMNQEVPSRVAVMGVAAFAWNDKDYDAQRTWHAAARDLA
GGDARVAAALLTFFDTQHLAPTFGSQPWQEQAPRLKAVLDHVREAVALGDAATRTQAIAELARTADEMAAAPQIIRDGVV
DKGFAEQSRPWLEAMEGWGHALQKTAAGLDAANRGDTQTPALFAEAAAIAAVASQIPSIPGATRFGGPVKIADGVLDRFI
AQAPHLIAYRQAAVTDSAAAK

Sequences:

>Translated_661_residues
MKRRNSKPGVRLLSVLVALGLAAPALAQSVTEPVTQPAIYPTPVSITLDGATITLGRSAVLVVAPGADKATVALVRSILD
GAGVTKIATATRLPATLDRPYIVLGTGDAAVVRDALTRSKATQDTHKEGYTLASVARDRGSLITLAGHDDDGLFHAAQTL
RQLVERPAIPTLTIQDYPSMPIRGTIEGFYGAPWSMSDRSKHIDFLARTKANTFIYSPKDDPYARDRWREAYPKATLKAL
GQLAATAKRNHVDFVYAISPGPTVCFSDPADAKALLRKFDAFRALGVRSFYVALDDIEYTKWNCERDKTTFGESGAQAAG
IAQSHLLNLVQADLVARHDAASELIMVPTEYYDAKESPYKEALRKHLDPKIVVQWTGTDVVPPAISIPDARAATKAFGRR
TLLWDNYPVNDFETSAGRLLMAPYARREAGLSAELSGIVSNPMNQEVPSRVAVMGVAAFAWNDKDYDAQRTWHAAARDLA
GGDARVAAALLTFFDTQHLAPTFGSQPWQEQAPRLKAVLDHVREAVALGDAATRTQAIAELARTADEMAAAPQIIRDGVV
DKGFAEQSRPWLEAMEGWGHALQKTAAGLDAANRGDTQTPALFAEAAAIAAVASQIPSIPGATRFGGPVKIADGVLDRFI
AQAPHLIAYRQAAVTDSAAAK
>Mature_661_residues
MKRRNSKPGVRLLSVLVALGLAAPALAQSVTEPVTQPAIYPTPVSITLDGATITLGRSAVLVVAPGADKATVALVRSILD
GAGVTKIATATRLPATLDRPYIVLGTGDAAVVRDALTRSKATQDTHKEGYTLASVARDRGSLITLAGHDDDGLFHAAQTL
RQLVERPAIPTLTIQDYPSMPIRGTIEGFYGAPWSMSDRSKHIDFLARTKANTFIYSPKDDPYARDRWREAYPKATLKAL
GQLAATAKRNHVDFVYAISPGPTVCFSDPADAKALLRKFDAFRALGVRSFYVALDDIEYTKWNCERDKTTFGESGAQAAG
IAQSHLLNLVQADLVARHDAASELIMVPTEYYDAKESPYKEALRKHLDPKIVVQWTGTDVVPPAISIPDARAATKAFGRR
TLLWDNYPVNDFETSAGRLLMAPYARREAGLSAELSGIVSNPMNQEVPSRVAVMGVAAFAWNDKDYDAQRTWHAAARDLA
GGDARVAAALLTFFDTQHLAPTFGSQPWQEQAPRLKAVLDHVREAVALGDAATRTQAIAELARTADEMAAAPQIIRDGVV
DKGFAEQSRPWLEAMEGWGHALQKTAAGLDAANRGDTQTPALFAEAAAIAAVASQIPSIPGATRFGGPVKIADGVLDRFI
AQAPHLIAYRQAAVTDSAAAK

Specific function: Biological function unknown. Capable of hydrolyzing the glycosidic link of O-GlcNAcylated proteins [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 fibronectin type-III domain [H]

Homologues:

Organism=Homo sapiens, GI215490056, Length=312, Percent_Identity=31.0897435897436, Blast_Score=159, Evalue=1e-38,
Organism=Homo sapiens, GI11024698, Length=282, Percent_Identity=32.6241134751773, Blast_Score=157, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI193211004, Length=316, Percent_Identity=28.4810126582279, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI193211002, Length=313, Percent_Identity=27.7955271565495, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24648670, Length=288, Percent_Identity=29.1666666666667, Blast_Score=132, Evalue=8e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015882
- InterPro:   IPR011496
- InterPro:   IPR008965
- InterPro:   IPR000421
- InterPro:   IPR018452
- InterPro:   IPR008957
- InterPro:   IPR003961
- InterPro:   IPR008979
- InterPro:   IPR017853
- InterPro:   IPR013783 [H]

Pfam domain/function: PF00754 F5_F8_type_C; PF00041 fn3; PF02838 Glyco_hydro_20b; PF07555 NAGidase [H]

EC number: =3.2.1.52 [H]

Molecular weight: Translated: 70957; Mature: 70957

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRRNSKPGVRLLSVLVALGLAAPALAQSVTEPVTQPAIYPTPVSITLDGATITLGRSAV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCEEEEECCCEE
LVVAPGADKATVALVRSILDGAGVTKIATATRLPATLDRPYIVLGTGDAAVVRDALTRSK
EEEECCCCHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHH
ATQDTHKEGYTLASVARDRGSLITLAGHDDDGLFHAAQTLRQLVERPAIPTLTIQDYPSM
CCCHHHHCCCCHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCC
PIRGTIEGFYGAPWSMSDRSKHIDFLARTKANTFIYSPKDDPYARDRWREAYPKATLKAL
CCCEECCCCCCCCCCCCCCHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHCCHHHHHHH
GQLAATAKRNHVDFVYAISPGPTVCFSDPADAKALLRKFDAFRALGVRSFYVALDDIEYT
HHHHHHHHCCCCEEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHCHHEEEEEEECCEEC
KWNCERDKTTFGESGAQAAGIAQSHLLNLVQADLVARHDAASELIMVPTEYYDAKESPYK
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECHHHCCCCCCHHH
EALRKHLDPKIVVQWTGTDVVPPAISIPDARAATKAFGRRTLLWDNYPVNDFETSAGRLL
HHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHCCEEEEECCCCCCCCCCCCCCEE
MAPYARREAGLSAELSGIVSNPMNQEVPSRVAVMGVAAFAWNDKDYDAQRTWHAAARDLA
ECCHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHCC
GGDARVAAALLTFFDTQHLAPTFGSQPWQEQAPRLKAVLDHVREAVALGDAATRTQAIAE
CCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
LARTADEMAAAPQIIRDGVVDKGFAEQSRPWLEAMEGWGHALQKTAAGLDAANRGDTQTP
HHHHHHHHHHHHHHHHCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
ALFAEAAAIAAVASQIPSIPGATRFGGPVKIADGVLDRFIAQAPHLIAYRQAAVTDSAAA
HHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHCC
K
C
>Mature Secondary Structure
MKRRNSKPGVRLLSVLVALGLAAPALAQSVTEPVTQPAIYPTPVSITLDGATITLGRSAV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCEEEEECCCEE
LVVAPGADKATVALVRSILDGAGVTKIATATRLPATLDRPYIVLGTGDAAVVRDALTRSK
EEEECCCCHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHH
ATQDTHKEGYTLASVARDRGSLITLAGHDDDGLFHAAQTLRQLVERPAIPTLTIQDYPSM
CCCHHHHCCCCHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCC
PIRGTIEGFYGAPWSMSDRSKHIDFLARTKANTFIYSPKDDPYARDRWREAYPKATLKAL
CCCEECCCCCCCCCCCCCCHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHCCHHHHHHH
GQLAATAKRNHVDFVYAISPGPTVCFSDPADAKALLRKFDAFRALGVRSFYVALDDIEYT
HHHHHHHHCCCCEEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHCHHEEEEEEECCEEC
KWNCERDKTTFGESGAQAAGIAQSHLLNLVQADLVARHDAASELIMVPTEYYDAKESPYK
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECHHHCCCCCCHHH
EALRKHLDPKIVVQWTGTDVVPPAISIPDARAATKAFGRRTLLWDNYPVNDFETSAGRLL
HHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHCCEEEEECCCCCCCCCCCCCCEE
MAPYARREAGLSAELSGIVSNPMNQEVPSRVAVMGVAAFAWNDKDYDAQRTWHAAARDLA
ECCHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHCC
GGDARVAAALLTFFDTQHLAPTFGSQPWQEQAPRLKAVLDHVREAVALGDAATRTQAIAE
CCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
LARTADEMAAAPQIIRDGVVDKGFAEQSRPWLEAMEGWGHALQKTAAGLDAANRGDTQTP
HHHHHHHHHHHHHHHHCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
ALFAEAAAIAAVASQIPSIPGATRFGGPVKIADGVLDRFIAQAPHLIAYRQAAVTDSAAA
HHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHCC
K
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA