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The map label for this gene is putA [H]

Identifier: 21244614

GI number: 21244614

Start: 4572445

End: 4575645

Strand: Direct

Name: putA [H]

Synonym: XAC3890

Alternate gene names: 21244614

Gene position: 4572445-4575645 (Clockwise)

Preceding gene: 21244607

Following gene: 21244615

Centisome position: 88.35

GC content: 63.98

Gene sequence:

>3201_bases
ATGAACGCTCAGCTCGACCCGCTTGCCTCCACCTCAGTTGCGCGCCCGCTGCTGGCGCCCGAACTGCCCGCCGCACCTGG
CGCTTTGCGTGCCGCCATCACCGCGGCCTGGCTCAAGGACGAAACCGAGCACGTGCGTGAATTGCTCGACCAGGCACGCC
TGCCTGTCGCTGAGCAAGCCAACGTGCAGGCGATCGCTGCCGATCTGGTTACCCGTGTGCGGGCGCGTTCGCAGGACCAG
GGCGCCATCGAAGCCTTCATGCGCCAATACGACCTGGGCAGCGAAGAAGGCGTGCTGCTGATGTGCGTGGCCGAGGCGCT
GTTGCGCATTCCCGACCAGGACACTGCCGACAAGCTGATCCGCGACAAGCTTGGCGATGCGGATTGGAAGAAGCATATGG
GCGGCAGCGATTCGGTGCTGGTCAACGCTTCCACCTGGGGCCTGATGCTGACCGGTCAGTTGGTGCAGCTCAACGACCTC
ACCCGCGCCGATGTGCCGGGCGCCTTCAAGCGCCTGATCGGCCGCGTCGGCGAGCCGGTCATTCGCCTGGCCGTGCGCCA
GGCCATGAAGATCATGGGCCATCAGTTCGTCATGGGCCGCACCATCGGCGAGGCGCTGTCGCGTTCGCGCAAGGGCGACA
ACGCCAACTACCGTTATTCGTTCGACATGCTTGGCGAAGGCGCGCTCACCATGAAGGATGCGCAGCGCTATCTGCAGGCG
TATCGGGATGCGATTCATGCGATCGGCCGCAGCGGTAGCTTCGTCGGTACCGATGTATTTGCCGCGCCCAGCATCTCGAT
CAAGTTGTCGGCGCTGTATCCGCGTTACGAGCATGCCAAGCGCGCCCGCGTGATGGCAGAGCTGGTGCCGGGCGTGCTGG
AACTTGCGCAGTTGGCCAAGTCGTACGGCATCGGCTACACCGTCGACGCCGAAGAAGCCGACCGGCTGGAACTGTCGCTG
GACATCATCGAGGCCACCTTCTCCGACCCGTCATTGGATGGCTGGGAAGGCTATGGCCTGGCCGTGCAGGCCTATCAAAA
ACGCACGCCGTACACGATCGATTTTCTTGCCGATCTGGCGCGCCGTGTCGGACGACGTATTCCGGTGCGCCTGGTCAAAG
GCGCGTACTGGGACGCAGAGATCAAGCGCGCGCAGATCGAAGGGCATCCCGGCTACCCGGTGTTTACGCGCAAGCAGAAC
ACCGACGTGTCGTACCTGGCATGCGCACGTCGCATGTTCGCGCACAGCGACGCGCTCTACCCGATGTTCGCCACGCACAA
CGCGCAGACCATTGCGGCAGTCCGTGCGATTGCGGCAGGCAAGACCTACGAGCACCAGAAACTGCACGGCATGGGCGATG
ACCTGTATGCCGAAGTGATTCCTGCCGATCGTCTCGATCTGCCATGCCGCGTCTATGCACCGGTCGGCTCGCACGAAGAT
CTGCTGCCGTATCTGGTGCGCCGTTTGCTCGAAAACGGCGCCAATTCCAGCTTCGTCAATCGCATCACCGACGAGGATGT
CGCCATCGAAGACCTCATCCGCGACCCGGTCGAGGCTGTGACGTCATTTACTTCCATCCCGCATCCCAAGATTCCACTGC
CAGCCGATTTGCTGCGTAGCCAGAACCAGAACAGGAAAAACTCCATGGGCGCCAATCTCGCCAACGACAACGATCTGCGC
CAGCTGGCCGAGCAACTCAACGCCGCGATCAAACCGTGGAAGGCCACGCCCCTGGTGCCTGGTGCGCTGATCAGCACGCC
CAGCCAAGCGGTGTTGAATCCGGCAGATCGCCGCGAGACGGTTGGACAGTGGCACCCGGCCGATCCGGACACCGTCCAGA
AGTCGCTGGCCAGCGCTGTGGCCGCGCAGCCGGCCTGGAACCGCACACCTGCAGCGAGCCGCGCCACTATCCTGGAACAT
GCAGCTGATCTGCTCGAAACGCGCATGTCCGAGTTCATGGCGATCTGCGTCAAGGAAGCCGGCAAGACGCTGCCCGACGC
AGTGGCCGAAGTCCGCGAGGCCGTCGATTTCCTGCGCTATTACGCCGGCCAGGCGCGTGCGCAGTTCGGTGCCCCGGAGC
GCCTGCCTGGACCGACCGGCGAATCCAACGAGCTGCAGCTGCACGGGCGTGGCGTCTTTGTCTGCATCAGTCCGTGGAAC
TTCCCGTTGGCGATCTTCCTCGGTCAGGTCGCCGCAGCGCTGGCGGCCGGCAACACGGTCATCGCCAAACCGGCCGAGCA
GACCAACCTGATCGGCTTTGCAGCGGTCAAGCTGCTGCACGAAGCCGGCGTACCGGAAGCGGCTGTGCAGTTCCTGCCAG
GTGATGGCGCTACCGTTGGTGCTGCGCTGACCAACGACCCGCGCGTTGCCGGCGTTGCATTCACCGGTTCTACCGAAACC
GCACGCATCATCAACCGCACCCTGGCCGCACGCGATGCTGCCATCGGCGTCTTGATCGCCGAAACCGGCGGCCAGAACGC
CTTCATCGCTGACTCGTCCTCGCTGCCCGAAGCGGTGGTCAAAGACGCCATTTCCAGTGCCTTCATCTCGGCCGGGCAGC
GCTGCTCCGCGGCGCGCGTCCTGTTCGTCCAGGACGACATCGCCGACAAGGTCATGACGATGCTGGCCGGTGCGATGGGT
GAGTTGAAGATCGGCGATCCGGGCCTGCCATCGACCGACGTTGGCCCTGTCATCGATGCCGATGCCCTCAAGATTCTCGA
CGATCACGCTGCACGCATGGATCGGCAAGCGCGTCTGATCGGCAGCACCGCCCTGGACGGTAGCACCGCACACGGCAGCT
TTTTCGCTCCACGCGCCTATGAGCTGACATCGCTGTCCCAGCTGCAGCGTGAAATCTTCGGGCCGGTGCTGCACGTGATT
CGCTGGAAAGCCGACCAGCTCGATGCCGTCATCGAGCAGATCAACGCGACCGGTTACGGCCTCACGTTGGGTGTCCATTC
GCGTATCGATGAGACAATCGACCGCATCACCTCGCGCGTGGCGGTAGGCAACGTCTACGTCAATCGCAACCAGATCGGCG
CCGTGGTCGGCGTACAACCGTTCGGCGGCCAGGGCCTGTCCGGCACCGGCCCCAAGGCCGGCGGCCCGCATTACCTGCTG
CGTTTCGCGACCGAGAAGGTCGTCACCGTCAACACCACCGCGGCAGGCGGCAACGCCTCGCTATTGACCTTGGGTGACTA
A

Upstream 100 bases:

>100_bases
CGGCGGCATGCACAAAACGGCGGGAAAGCCGCCGCTTCCACACAAGTGCGCGAGCCGTTTGGCTCACTAGAATGAGCACG
GAATCCAAGGCACCTTTCGC

Downstream 100 bases:

>100_bases
TGCCGGCCAGCAGATGCCGGCGTCTGCACGCTGCTCGGTTCGTCATTACCGATTGCAGCCAGATGTACTGTCAGCACAAC
AACAAAAACCCCGCTCATGC

Product: bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase

Products: NA

Alternate protein names: Proline dehydrogenase; Proline oxidase; Delta-1-pyrroline-5-carboxylate dehydrogenase; P5C dehydrogenase [H]

Number of amino acids: Translated: 1066; Mature: 1066

Protein sequence:

>1066_residues
MNAQLDPLASTSVARPLLAPELPAAPGALRAAITAAWLKDETEHVRELLDQARLPVAEQANVQAIAADLVTRVRARSQDQ
GAIEAFMRQYDLGSEEGVLLMCVAEALLRIPDQDTADKLIRDKLGDADWKKHMGGSDSVLVNASTWGLMLTGQLVQLNDL
TRADVPGAFKRLIGRVGEPVIRLAVRQAMKIMGHQFVMGRTIGEALSRSRKGDNANYRYSFDMLGEGALTMKDAQRYLQA
YRDAIHAIGRSGSFVGTDVFAAPSISIKLSALYPRYEHAKRARVMAELVPGVLELAQLAKSYGIGYTVDAEEADRLELSL
DIIEATFSDPSLDGWEGYGLAVQAYQKRTPYTIDFLADLARRVGRRIPVRLVKGAYWDAEIKRAQIEGHPGYPVFTRKQN
TDVSYLACARRMFAHSDALYPMFATHNAQTIAAVRAIAAGKTYEHQKLHGMGDDLYAEVIPADRLDLPCRVYAPVGSHED
LLPYLVRRLLENGANSSFVNRITDEDVAIEDLIRDPVEAVTSFTSIPHPKIPLPADLLRSQNQNRKNSMGANLANDNDLR
QLAEQLNAAIKPWKATPLVPGALISTPSQAVLNPADRRETVGQWHPADPDTVQKSLASAVAAQPAWNRTPAASRATILEH
AADLLETRMSEFMAICVKEAGKTLPDAVAEVREAVDFLRYYAGQARAQFGAPERLPGPTGESNELQLHGRGVFVCISPWN
FPLAIFLGQVAAALAAGNTVIAKPAEQTNLIGFAAVKLLHEAGVPEAAVQFLPGDGATVGAALTNDPRVAGVAFTGSTET
ARIINRTLAARDAAIGVLIAETGGQNAFIADSSSLPEAVVKDAISSAFISAGQRCSAARVLFVQDDIADKVMTMLAGAMG
ELKIGDPGLPSTDVGPVIDADALKILDDHAARMDRQARLIGSTALDGSTAHGSFFAPRAYELTSLSQLQREIFGPVLHVI
RWKADQLDAVIEQINATGYGLTLGVHSRIDETIDRITSRVAVGNVYVNRNQIGAVVGVQPFGGQGLSGTGPKAGGPHYLL
RFATEKVVTVNTTAAGGNASLLTLGD

Sequences:

>Translated_1066_residues
MNAQLDPLASTSVARPLLAPELPAAPGALRAAITAAWLKDETEHVRELLDQARLPVAEQANVQAIAADLVTRVRARSQDQ
GAIEAFMRQYDLGSEEGVLLMCVAEALLRIPDQDTADKLIRDKLGDADWKKHMGGSDSVLVNASTWGLMLTGQLVQLNDL
TRADVPGAFKRLIGRVGEPVIRLAVRQAMKIMGHQFVMGRTIGEALSRSRKGDNANYRYSFDMLGEGALTMKDAQRYLQA
YRDAIHAIGRSGSFVGTDVFAAPSISIKLSALYPRYEHAKRARVMAELVPGVLELAQLAKSYGIGYTVDAEEADRLELSL
DIIEATFSDPSLDGWEGYGLAVQAYQKRTPYTIDFLADLARRVGRRIPVRLVKGAYWDAEIKRAQIEGHPGYPVFTRKQN
TDVSYLACARRMFAHSDALYPMFATHNAQTIAAVRAIAAGKTYEHQKLHGMGDDLYAEVIPADRLDLPCRVYAPVGSHED
LLPYLVRRLLENGANSSFVNRITDEDVAIEDLIRDPVEAVTSFTSIPHPKIPLPADLLRSQNQNRKNSMGANLANDNDLR
QLAEQLNAAIKPWKATPLVPGALISTPSQAVLNPADRRETVGQWHPADPDTVQKSLASAVAAQPAWNRTPAASRATILEH
AADLLETRMSEFMAICVKEAGKTLPDAVAEVREAVDFLRYYAGQARAQFGAPERLPGPTGESNELQLHGRGVFVCISPWN
FPLAIFLGQVAAALAAGNTVIAKPAEQTNLIGFAAVKLLHEAGVPEAAVQFLPGDGATVGAALTNDPRVAGVAFTGSTET
ARIINRTLAARDAAIGVLIAETGGQNAFIADSSSLPEAVVKDAISSAFISAGQRCSAARVLFVQDDIADKVMTMLAGAMG
ELKIGDPGLPSTDVGPVIDADALKILDDHAARMDRQARLIGSTALDGSTAHGSFFAPRAYELTSLSQLQREIFGPVLHVI
RWKADQLDAVIEQINATGYGLTLGVHSRIDETIDRITSRVAVGNVYVNRNQIGAVVGVQPFGGQGLSGTGPKAGGPHYLL
RFATEKVVTVNTTAAGGNASLLTLGD
>Mature_1066_residues
MNAQLDPLASTSVARPLLAPELPAAPGALRAAITAAWLKDETEHVRELLDQARLPVAEQANVQAIAADLVTRVRARSQDQ
GAIEAFMRQYDLGSEEGVLLMCVAEALLRIPDQDTADKLIRDKLGDADWKKHMGGSDSVLVNASTWGLMLTGQLVQLNDL
TRADVPGAFKRLIGRVGEPVIRLAVRQAMKIMGHQFVMGRTIGEALSRSRKGDNANYRYSFDMLGEGALTMKDAQRYLQA
YRDAIHAIGRSGSFVGTDVFAAPSISIKLSALYPRYEHAKRARVMAELVPGVLELAQLAKSYGIGYTVDAEEADRLELSL
DIIEATFSDPSLDGWEGYGLAVQAYQKRTPYTIDFLADLARRVGRRIPVRLVKGAYWDAEIKRAQIEGHPGYPVFTRKQN
TDVSYLACARRMFAHSDALYPMFATHNAQTIAAVRAIAAGKTYEHQKLHGMGDDLYAEVIPADRLDLPCRVYAPVGSHED
LLPYLVRRLLENGANSSFVNRITDEDVAIEDLIRDPVEAVTSFTSIPHPKIPLPADLLRSQNQNRKNSMGANLANDNDLR
QLAEQLNAAIKPWKATPLVPGALISTPSQAVLNPADRRETVGQWHPADPDTVQKSLASAVAAQPAWNRTPAASRATILEH
AADLLETRMSEFMAICVKEAGKTLPDAVAEVREAVDFLRYYAGQARAQFGAPERLPGPTGESNELQLHGRGVFVCISPWN
FPLAIFLGQVAAALAAGNTVIAKPAEQTNLIGFAAVKLLHEAGVPEAAVQFLPGDGATVGAALTNDPRVAGVAFTGSTET
ARIINRTLAARDAAIGVLIAETGGQNAFIADSSSLPEAVVKDAISSAFISAGQRCSAARVLFVQDDIADKVMTMLAGAMG
ELKIGDPGLPSTDVGPVIDADALKILDDHAARMDRQARLIGSTALDGSTAHGSFFAPRAYELTSLSQLQREIFGPVLHVI
RWKADQLDAVIEQINATGYGLTLGVHSRIDETIDRITSRVAVGNVYVNRNQIGAVVGVQPFGGQGLSGTGPKAGGPHYLL
RFATEKVVTVNTTAAGGNASLLTLGD

Specific function: Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon [H]

COG id: COG4230

COG function: function code C; Delta 1-pyrroline-5-carboxylate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI238859541, Length=493, Percent_Identity=32.4543610547667, Blast_Score=206, Evalue=7e-53,
Organism=Homo sapiens, GI25777736, Length=493, Percent_Identity=32.4543610547667, Blast_Score=206, Evalue=7e-53,
Organism=Homo sapiens, GI25777734, Length=493, Percent_Identity=32.4543610547667, Blast_Score=206, Evalue=7e-53,
Organism=Homo sapiens, GI153266822, Length=474, Percent_Identity=31.0126582278481, Blast_Score=194, Evalue=5e-49,
Organism=Homo sapiens, GI21361176, Length=478, Percent_Identity=32.4267782426778, Blast_Score=179, Evalue=2e-44,
Organism=Homo sapiens, GI25777724, Length=474, Percent_Identity=30.8016877637131, Blast_Score=173, Evalue=7e-43,
Organism=Homo sapiens, GI25777732, Length=481, Percent_Identity=31.3929313929314, Blast_Score=173, Evalue=8e-43,
Organism=Homo sapiens, GI21614513, Length=417, Percent_Identity=30.9352517985612, Blast_Score=172, Evalue=1e-42,
Organism=Homo sapiens, GI238814322, Length=499, Percent_Identity=27.4549098196393, Blast_Score=170, Evalue=6e-42,
Organism=Homo sapiens, GI12007648, Length=464, Percent_Identity=30.1724137931034, Blast_Score=168, Evalue=3e-41,
Organism=Homo sapiens, GI25777730, Length=434, Percent_Identity=31.1059907834101, Blast_Score=163, Evalue=8e-40,
Organism=Homo sapiens, GI25777728, Length=431, Percent_Identity=31.0904872389791, Blast_Score=163, Evalue=9e-40,
Organism=Homo sapiens, GI115387104, Length=456, Percent_Identity=28.9473684210526, Blast_Score=159, Evalue=1e-38,
Organism=Homo sapiens, GI4507229, Length=429, Percent_Identity=31.002331002331, Blast_Score=151, Evalue=3e-36,
Organism=Homo sapiens, GI188035924, Length=484, Percent_Identity=27.4793388429752, Blast_Score=144, Evalue=4e-34,
Organism=Homo sapiens, GI310128093, Length=465, Percent_Identity=28.1720430107527, Blast_Score=143, Evalue=7e-34,
Organism=Homo sapiens, GI310128103, Length=465, Percent_Identity=28.1720430107527, Blast_Score=143, Evalue=8e-34,
Organism=Homo sapiens, GI25777721, Length=442, Percent_Identity=29.8642533936652, Blast_Score=140, Evalue=5e-33,
Organism=Homo sapiens, GI25952152, Length=455, Percent_Identity=28.1318681318681, Blast_Score=130, Evalue=6e-30,
Organism=Homo sapiens, GI310128091, Length=392, Percent_Identity=29.8469387755102, Blast_Score=129, Evalue=1e-29,
Organism=Homo sapiens, GI25777726, Length=476, Percent_Identity=27.9411764705882, Blast_Score=125, Evalue=3e-28,
Organism=Homo sapiens, GI11095441, Length=431, Percent_Identity=26.4501160092807, Blast_Score=115, Evalue=3e-25,
Organism=Homo sapiens, GI310128087, Length=299, Percent_Identity=29.7658862876254, Blast_Score=107, Evalue=8e-23,
Organism=Homo sapiens, GI4502043, Length=329, Percent_Identity=25.8358662613982, Blast_Score=98, Evalue=5e-20,
Organism=Homo sapiens, GI238814371, Length=329, Percent_Identity=25.8358662613982, Blast_Score=98, Evalue=5e-20,
Organism=Homo sapiens, GI71773324, Length=329, Percent_Identity=25.8358662613982, Blast_Score=97, Evalue=6e-20,
Organism=Homo sapiens, GI310128089, Length=331, Percent_Identity=28.3987915407855, Blast_Score=95, Evalue=5e-19,
Organism=Homo sapiens, GI310128095, Length=317, Percent_Identity=28.0757097791798, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI73695881, Length=326, Percent_Identity=24.8466257668712, Blast_Score=87, Evalue=8e-17,
Organism=Homo sapiens, GI73695879, Length=326, Percent_Identity=24.8466257668712, Blast_Score=87, Evalue=8e-17,
Organism=Homo sapiens, GI301500698, Length=290, Percent_Identity=28.6206896551724, Blast_Score=86, Evalue=2e-16,
Organism=Homo sapiens, GI310128099, Length=230, Percent_Identity=28.2608695652174, Blast_Score=84, Evalue=9e-16,
Organism=Homo sapiens, GI310128101, Length=230, Percent_Identity=28.2608695652174, Blast_Score=84, Evalue=1e-15,
Organism=Homo sapiens, GI310128097, Length=264, Percent_Identity=28.4090909090909, Blast_Score=82, Evalue=4e-15,
Organism=Escherichia coli, GI1787250, Length=1038, Percent_Identity=52.9865125240848, Blast_Score=1038, Evalue=0.0,
Organism=Escherichia coli, GI1789015, Length=459, Percent_Identity=32.0261437908497, Blast_Score=183, Evalue=5e-47,
Organism=Escherichia coli, GI87081896, Length=485, Percent_Identity=31.5463917525773, Blast_Score=179, Evalue=6e-46,
Organism=Escherichia coli, GI1787684, Length=471, Percent_Identity=32.0594479830149, Blast_Score=176, Evalue=5e-45,
Organism=Escherichia coli, GI1788042, Length=436, Percent_Identity=31.1926605504587, Blast_Score=162, Evalue=9e-41,
Organism=Escherichia coli, GI1787715, Length=411, Percent_Identity=32.1167883211679, Blast_Score=161, Evalue=2e-40,
Organism=Escherichia coli, GI1787558, Length=449, Percent_Identity=30.0668151447661, Blast_Score=154, Evalue=3e-38,
Organism=Escherichia coli, GI1786504, Length=449, Percent_Identity=28.0623608017817, Blast_Score=149, Evalue=1e-36,
Organism=Escherichia coli, GI87082295, Length=428, Percent_Identity=29.2056074766355, Blast_Score=129, Evalue=1e-30,
Organism=Escherichia coli, GI87081926, Length=427, Percent_Identity=26.6978922716628, Blast_Score=119, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17534447, Length=473, Percent_Identity=32.9809725158562, Blast_Score=200, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI115532534, Length=387, Percent_Identity=34.3669250645995, Blast_Score=170, Evalue=4e-42,
Organism=Caenorhabditis elegans, GI25144435, Length=471, Percent_Identity=32.6963906581741, Blast_Score=168, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI17562198, Length=470, Percent_Identity=30.4255319148936, Blast_Score=164, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI25143874, Length=530, Percent_Identity=28.8679245283019, Blast_Score=164, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI25143876, Length=475, Percent_Identity=29.2631578947368, Blast_Score=161, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI32564736, Length=430, Percent_Identity=33.7209302325581, Blast_Score=160, Evalue=5e-39,
Organism=Caenorhabditis elegans, GI133930964, Length=446, Percent_Identity=29.5964125560538, Blast_Score=157, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI17534119, Length=461, Percent_Identity=29.5010845986985, Blast_Score=155, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI71995606, Length=444, Percent_Identity=29.954954954955, Blast_Score=150, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI32564151, Length=425, Percent_Identity=30.1176470588235, Blast_Score=149, Evalue=9e-36,
Organism=Caenorhabditis elegans, GI115534176, Length=453, Percent_Identity=30.4635761589404, Blast_Score=148, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI71995613, Length=401, Percent_Identity=29.925187032419, Blast_Score=140, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI17551164, Length=452, Percent_Identity=28.5398230088496, Blast_Score=135, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI71990744, Length=307, Percent_Identity=30.2931596091205, Blast_Score=122, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI71986308, Length=427, Percent_Identity=27.8688524590164, Blast_Score=121, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI25146391, Length=347, Percent_Identity=25.3602305475504, Blast_Score=85, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI32566756, Length=347, Percent_Identity=25.3602305475504, Blast_Score=85, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI25146394, Length=347, Percent_Identity=25.3602305475504, Blast_Score=84, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17564084, Length=322, Percent_Identity=24.223602484472, Blast_Score=78, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6320917, Length=451, Percent_Identity=31.4855875831486, Blast_Score=182, Evalue=3e-46,
Organism=Saccharomyces cerevisiae, GI6324950, Length=457, Percent_Identity=29.7592997811816, Blast_Score=167, Evalue=7e-42,
Organism=Saccharomyces cerevisiae, GI6325196, Length=420, Percent_Identity=29.2857142857143, Blast_Score=157, Evalue=1e-38,
Organism=Saccharomyces cerevisiae, GI6323821, Length=457, Percent_Identity=29.9781181619256, Blast_Score=157, Evalue=1e-38,
Organism=Saccharomyces cerevisiae, GI6321826, Length=478, Percent_Identity=26.7782426778243, Blast_Score=155, Evalue=3e-38,
Organism=Saccharomyces cerevisiae, GI6323822, Length=457, Percent_Identity=29.3216630196937, Blast_Score=152, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6319478, Length=456, Percent_Identity=27.8508771929825, Blast_Score=148, Evalue=5e-36,
Organism=Saccharomyces cerevisiae, GI6321828, Length=507, Percent_Identity=24.65483234714, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24668425, Length=521, Percent_Identity=30.1343570057582, Blast_Score=202, Evalue=1e-51,
Organism=Drosophila melanogaster, GI24668417, Length=521, Percent_Identity=30.1343570057582, Blast_Score=202, Evalue=1e-51,
Organism=Drosophila melanogaster, GI24668413, Length=521, Percent_Identity=30.1343570057582, Blast_Score=202, Evalue=1e-51,
Organism=Drosophila melanogaster, GI281362580, Length=474, Percent_Identity=31.6455696202532, Blast_Score=175, Evalue=1e-43,
Organism=Drosophila melanogaster, GI62472918, Length=474, Percent_Identity=31.6455696202532, Blast_Score=175, Evalue=1e-43,
Organism=Drosophila melanogaster, GI62472926, Length=474, Percent_Identity=31.6455696202532, Blast_Score=175, Evalue=1e-43,
Organism=Drosophila melanogaster, GI62472936, Length=474, Percent_Identity=31.6455696202532, Blast_Score=175, Evalue=1e-43,
Organism=Drosophila melanogaster, GI21356737, Length=474, Percent_Identity=31.6455696202532, Blast_Score=175, Evalue=1e-43,
Organism=Drosophila melanogaster, GI20129399, Length=518, Percent_Identity=29.9227799227799, Blast_Score=174, Evalue=3e-43,
Organism=Drosophila melanogaster, GI28571802, Length=480, Percent_Identity=29.1666666666667, Blast_Score=167, Evalue=5e-41,
Organism=Drosophila melanogaster, GI28571800, Length=480, Percent_Identity=29.1666666666667, Blast_Score=167, Evalue=5e-41,
Organism=Drosophila melanogaster, GI28571806, Length=480, Percent_Identity=29.1666666666667, Blast_Score=167, Evalue=5e-41,
Organism=Drosophila melanogaster, GI28571798, Length=480, Percent_Identity=29.1666666666667, Blast_Score=166, Evalue=6e-41,
Organism=Drosophila melanogaster, GI28571796, Length=480, Percent_Identity=29.1666666666667, Blast_Score=166, Evalue=6e-41,
Organism=Drosophila melanogaster, GI28571794, Length=480, Percent_Identity=29.1666666666667, Blast_Score=166, Evalue=6e-41,
Organism=Drosophila melanogaster, GI24650465, Length=462, Percent_Identity=28.5714285714286, Blast_Score=160, Evalue=4e-39,
Organism=Drosophila melanogaster, GI24585660, Length=486, Percent_Identity=28.3950617283951, Blast_Score=160, Evalue=4e-39,
Organism=Drosophila melanogaster, GI24666674, Length=455, Percent_Identity=28.7912087912088, Blast_Score=141, Evalue=2e-33,
Organism=Drosophila melanogaster, GI28574525, Length=507, Percent_Identity=24.4575936883629, Blast_Score=137, Evalue=3e-32,
Organism=Drosophila melanogaster, GI24638878, Length=407, Percent_Identity=27.7641277641278, Blast_Score=105, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24638876, Length=407, Percent_Identity=27.7641277641278, Blast_Score=105, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005933
- InterPro:   IPR002872 [H]

Pfam domain/function: PF00171 Aldedh; PF01619 Pro_dh [H]

EC number: =1.5.99.8; =1.5.1.12 [H]

Molecular weight: Translated: 114560; Mature: 114560

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAQLDPLASTSVARPLLAPELPAAPGALRAAITAAWLKDETEHVRELLDQARLPVAEQA
CCCCCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCC
NVQAIAADLVTRVRARSQDQGAIEAFMRQYDLGSEEGVLLMCVAEALLRIPDQDTADKLI
CHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCEEHHHHHHHHHHCCCCCHHHHHH
RDKLGDADWKKHMGGSDSVLVNASTWGLMLTGQLVQLNDLTRADVPGAFKRLIGRVGEPV
HHHCCCCHHHHHCCCCCCEEEEECCCCEEEECCEEEECCCCCCCCCHHHHHHHHHHCHHH
IRLAVRQAMKIMGHQFVMGRTIGEALSRSRKGDNANYRYSFDMLGEGALTMKDAQRYLQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCEEHHHHHHHHHH
YRDAIHAIGRSGSFVGTDVFAAPSISIKLSALYPRYEHAKRARVMAELVPGVLELAQLAK
HHHHHHHHCCCCCEECCCCEECCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
SYGIGYTVDAEEADRLELSLDIIEATFSDPSLDGWEGYGLAVQAYQKRTPYTIDFLADLA
HHCCCEEECCCCCCCEEEEEEEHHHHCCCCCCCCCCCCCCEEEHHHCCCCEEHHHHHHHH
RRVGRRIPVRLVKGAYWDAEIKRAQIEGHPGYPVFTRKQNTDVSYLACARRMFAHSDALY
HHHCCCCCHHHHCCCCCCCHHHHEEECCCCCCCEEECCCCCCHHHHHHHHHHHHCCCCCC
PMFATHNAQTIAAVRAIAAGKTYEHQKLHGMGDDLYAEVIPADRLDLPCRVYAPVGSHED
EEEECCCCHHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHCCCCCCCCCEEEEECCCCCCC
LLPYLVRRLLENGANSSFVNRITDEDVAIEDLIRDPVEAVTSFTSIPHPKIPLPADLLRS
HHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHC
QNQNRKNSMGANLANDNDLRQLAEQLNAAIKPWKATPLVPGALISTPSQAVLNPADRRET
CCCCCHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCHHHCCCHHHHHH
VGQWHPADPDTVQKSLASAVAAQPAWNRTPAASRATILEHAADLLETRMSEFMAICVKEA
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GKTLPDAVAEVREAVDFLRYYAGQARAQFGAPERLPGPTGESNELQLHGRGVFVCISPWN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCEEEEEECCCC
FPLAIFLGQVAAALAAGNTVIAKPAEQTNLIGFAAVKLLHEAGVPEAAVQFLPGDGATVG
CHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHCCCCHHHHEECCCCCCEEC
AALTNDPRVAGVAFTGSTETARIINRTLAARDAAIGVLIAETGGQNAFIADSSSLPEAVV
CEECCCCCEEEEEEECCCHHHHHHHHHHHHHHCEEEEEEEECCCCEEEEECCCCCHHHHH
KDAISSAFISAGQRCSAARVLFVQDDIADKVMTMLAGAMGELKIGDPGLPSTDVGPVIDA
HHHHHHHHHHCCCCCCCEEEEEEEHHHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCCCH
DALKILDDHAARMDRQARLIGSTALDGSTAHGSFFAPRAYELTSLSQLQREIFGPVLHVI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
RWKADQLDAVIEQINATGYGLTLGVHSRIDETIDRITSRVAVGNVYVNRNQIGAVVGVQP
HCCHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHCEEEEECCCCCEEEECCC
FGGQGLSGTGPKAGGPHYLLRFATEKVVTVNTTAAGGNASLLTLGD
CCCCCCCCCCCCCCCCHHHHEECCCCEEEEEEECCCCCEEEEEECC
>Mature Secondary Structure
MNAQLDPLASTSVARPLLAPELPAAPGALRAAITAAWLKDETEHVRELLDQARLPVAEQA
CCCCCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCC
NVQAIAADLVTRVRARSQDQGAIEAFMRQYDLGSEEGVLLMCVAEALLRIPDQDTADKLI
CHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCEEHHHHHHHHHHCCCCCHHHHHH
RDKLGDADWKKHMGGSDSVLVNASTWGLMLTGQLVQLNDLTRADVPGAFKRLIGRVGEPV
HHHCCCCHHHHHCCCCCCEEEEECCCCEEEECCEEEECCCCCCCCCHHHHHHHHHHCHHH
IRLAVRQAMKIMGHQFVMGRTIGEALSRSRKGDNANYRYSFDMLGEGALTMKDAQRYLQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCEEHHHHHHHHHH
YRDAIHAIGRSGSFVGTDVFAAPSISIKLSALYPRYEHAKRARVMAELVPGVLELAQLAK
HHHHHHHHCCCCCEECCCCEECCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
SYGIGYTVDAEEADRLELSLDIIEATFSDPSLDGWEGYGLAVQAYQKRTPYTIDFLADLA
HHCCCEEECCCCCCCEEEEEEEHHHHCCCCCCCCCCCCCCEEEHHHCCCCEEHHHHHHHH
RRVGRRIPVRLVKGAYWDAEIKRAQIEGHPGYPVFTRKQNTDVSYLACARRMFAHSDALY
HHHCCCCCHHHHCCCCCCCHHHHEEECCCCCCCEEECCCCCCHHHHHHHHHHHHCCCCCC
PMFATHNAQTIAAVRAIAAGKTYEHQKLHGMGDDLYAEVIPADRLDLPCRVYAPVGSHED
EEEECCCCHHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHCCCCCCCCCEEEEECCCCCCC
LLPYLVRRLLENGANSSFVNRITDEDVAIEDLIRDPVEAVTSFTSIPHPKIPLPADLLRS
HHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHC
QNQNRKNSMGANLANDNDLRQLAEQLNAAIKPWKATPLVPGALISTPSQAVLNPADRRET
CCCCCHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCHHHCCCHHHHHH
VGQWHPADPDTVQKSLASAVAAQPAWNRTPAASRATILEHAADLLETRMSEFMAICVKEA
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GKTLPDAVAEVREAVDFLRYYAGQARAQFGAPERLPGPTGESNELQLHGRGVFVCISPWN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCEEEEEECCCC
FPLAIFLGQVAAALAAGNTVIAKPAEQTNLIGFAAVKLLHEAGVPEAAVQFLPGDGATVG
CHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHCCCCHHHHEECCCCCCEEC
AALTNDPRVAGVAFTGSTETARIINRTLAARDAAIGVLIAETGGQNAFIADSSSLPEAVV
CEECCCCCEEEEEEECCCHHHHHHHHHHHHHHCEEEEEEEECCCCEEEEECCCCCHHHHH
KDAISSAFISAGQRCSAARVLFVQDDIADKVMTMLAGAMGELKIGDPGLPSTDVGPVIDA
HHHHHHHHHHCCCCCCCEEEEEEEHHHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCCCH
DALKILDDHAARMDRQARLIGSTALDGSTAHGSFFAPRAYELTSLSQLQREIFGPVLHVI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
RWKADQLDAVIEQINATGYGLTLGVHSRIDETIDRITSRVAVGNVYVNRNQIGAVVGVQP
HCCHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHCEEEEECCCCCEEEECCC
FGGQGLSGTGPKAGGPHYLLRFATEKVVTVNTTAAGGNASLLTLGD
CCCCCCCCCCCCCCCCHHHHEECCCCEEEEEEECCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7966312; 8905232; 9278503; 3325781; 12514740 [H]