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The map label for this gene is htrB [H]

Identifier: 21244514

GI number: 21244514

Start: 4458699

End: 4459613

Strand: Direct

Name: htrB [H]

Synonym: XAC3790

Alternate gene names: 21244514

Gene position: 4458699-4459613 (Clockwise)

Preceding gene: 21244503

Following gene: 21244516

Centisome position: 86.15

GC content: 70.71

Gene sequence:

>915_bases
ATGACACCTGATGTTCGCGCTCGCCTGTTGTACGCAACCGCCGCCACCGTGGGCCGCTTGCCGTGGCCGTTGCTCAAGCG
CGTGGCCGACACGCTGGCCTGGAGCTGGCGCAAGCTCAATGCACGCGAATCACGCGTGGCGCGCCGCAATCTGGAGCTGG
CGTATCCGGAACTGAGCGCCGAGCAGCGCGCGCGCTTGCATGCGCAGATCCTGCGCTCGACCGCGCGGCAGACGCTGGAA
GTGCTGCGCACCTGGACCCGCCCGCCGGCGGAGAACCTGGCACGCCTGCAGCGCAACGGCCAGGAACTCTACGACGCTGC
GCTCGCCTCCGGGCGCGGGGTCATCGTGGCGGCGCCGCATTTCGGCAACTGGGAACTGCTCAACCAGTGGCTGTCCGAGC
GCGGGCCGATCGCGATTGTCTACCGCCCGCCGGAGTCCGAGGCGGTGGACGGCTTCCTGCAGCTGGCACGCGGCGGCGAC
AACGTGCGCCAGGTACGCGCCGAAGGCCCGGCGGTGCGGCAGTTGTTCAAGGTGCTCAAGGACGGCGGCGCGGTCGGCAT
CCTGCCCGACCAGCAGCCCAAGGCCGGCGACGGCGTGTTCGCGCCGTTCTTCGGCATTCCGGCCTTGACCATGACCTTGG
TCAACCGGCTGGCCGAGCGGACCGGGGCGATCGTGCTGTACGGCTGGTGCGAGCGCGCCGGCGACGATCTGCAGTTCGCG
CTGCACGTGCAACCGGCCGACCCCGCGGTGGCCGATGCGGACCCGGTGCGTGCGGCCAGCGCGCTCAACGCCGGCATCGA
GCAGATCGCCCGGCGCGACCCGGCGCAATATCAGTGGACCTACAAGCGCTACACCCTGCGCCCGCCGGGCAGCGGCGAGG
CCAATCCGTATGCGACCGAGCGGCATCCGCATTGA

Upstream 100 bases:

>100_bases
GGGCATTCTCGGGCAGCAAACTGTGCCGCGCAGCATGCCCAGCGCCGCCGGCACTGTCACGCGCGGGCCTTCGCGGTCTG
CGCTGTTTAGAATTGCGCGG

Downstream 100 bases:

>100_bases
ATGCAGCGCCACATCTCACTTGATTGCTCAGCGCATCTACCAACACGTAGCGGGCAGTCGTAAGGTGGGTGCGGACGTCG
CGCTCAGAACCGCAGTGTAA

Product: lipid A biosynthesis lauroyl acyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MTPDVRARLLYATAATVGRLPWPLLKRVADTLAWSWRKLNARESRVARRNLELAYPELSAEQRARLHAQILRSTARQTLE
VLRTWTRPPAENLARLQRNGQELYDAALASGRGVIVAAPHFGNWELLNQWLSERGPIAIVYRPPESEAVDGFLQLARGGD
NVRQVRAEGPAVRQLFKVLKDGGAVGILPDQQPKAGDGVFAPFFGIPALTMTLVNRLAERTGAIVLYGWCERAGDDLQFA
LHVQPADPAVADADPVRAASALNAGIEQIARRDPAQYQWTYKRYTLRPPGSGEANPYATERHPH

Sequences:

>Translated_304_residues
MTPDVRARLLYATAATVGRLPWPLLKRVADTLAWSWRKLNARESRVARRNLELAYPELSAEQRARLHAQILRSTARQTLE
VLRTWTRPPAENLARLQRNGQELYDAALASGRGVIVAAPHFGNWELLNQWLSERGPIAIVYRPPESEAVDGFLQLARGGD
NVRQVRAEGPAVRQLFKVLKDGGAVGILPDQQPKAGDGVFAPFFGIPALTMTLVNRLAERTGAIVLYGWCERAGDDLQFA
LHVQPADPAVADADPVRAASALNAGIEQIARRDPAQYQWTYKRYTLRPPGSGEANPYATERHPH
>Mature_303_residues
TPDVRARLLYATAATVGRLPWPLLKRVADTLAWSWRKLNARESRVARRNLELAYPELSAEQRARLHAQILRSTARQTLEV
LRTWTRPPAENLARLQRNGQELYDAALASGRGVIVAAPHFGNWELLNQWLSERGPIAIVYRPPESEAVDGFLQLARGGDN
VRQVRAEGPAVRQLFKVLKDGGAVGILPDQQPKAGDGVFAPFFGIPALTMTLVNRLAERTGAIVLYGWCERAGDDLQFAL
HVQPADPAVADADPVRAASALNAGIEQIARRDPAQYQWTYKRYTLRPPGSGEANPYATERHPH

Specific function: Unknown

COG id: COG1560

COG function: function code M; Lauroyl/myristoyl acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the htrB/msbB family [H]

Homologues:

Organism=Escherichia coli, GI87082094, Length=273, Percent_Identity=28.2051282051282, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787292, Length=275, Percent_Identity=25.8181818181818, Blast_Score=93, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004960
- InterPro:   IPR011920 [H]

Pfam domain/function: PF03279 Lip_A_acyltrans [H]

EC number: 2.3.1.-

Molecular weight: Translated: 33714; Mature: 33583

Theoretical pI: Translated: 10.16; Mature: 10.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPDVRARLLYATAATVGRLPWPLLKRVADTLAWSWRKLNARESRVARRNLELAYPELSA
CCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCEECCCCCH
EQRARLHAQILRSTARQTLEVLRTWTRPPAENLARLQRNGQELYDAALASGRGVIVAAPH
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHCCCEEEEECCC
FGNWELLNQWLSERGPIAIVYRPPESEAVDGFLQLARGGDNVRQVRAEGPAVRQLFKVLK
CCCHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHH
DGGAVGILPDQQPKAGDGVFAPFFGIPALTMTLVNRLAERTGAIVLYGWCERAGDDLQFA
CCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCEEEE
LHVQPADPAVADADPVRAASALNAGIEQIARRDPAQYQWTYKRYTLRPPGSGEANPYATE
EEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCCCCCCCC
RHPH
CCCC
>Mature Secondary Structure 
TPDVRARLLYATAATVGRLPWPLLKRVADTLAWSWRKLNARESRVARRNLELAYPELSA
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCEECCCCCH
EQRARLHAQILRSTARQTLEVLRTWTRPPAENLARLQRNGQELYDAALASGRGVIVAAPH
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHCCCEEEEECCC
FGNWELLNQWLSERGPIAIVYRPPESEAVDGFLQLARGGDNVRQVRAEGPAVRQLFKVLK
CCCHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHH
DGGAVGILPDQQPKAGDGVFAPFFGIPALTMTLVNRLAERTGAIVLYGWCERAGDDLQFA
CCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCEEEE
LHVQPADPAVADADPVRAASALNAGIEQIARRDPAQYQWTYKRYTLRPPGSGEANPYATE
EEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCCCCCCCC
RHPH
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]