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The map label for this gene is yafC [H]

Identifier: 21244486

GI number: 21244486

Start: 4438977

End: 4439903

Strand: Reverse

Name: yafC [H]

Synonym: XAC3761

Alternate gene names: 21244486

Gene position: 4439903-4438977 (Counterclockwise)

Preceding gene: 21244496

Following gene: 21244484

Centisome position: 85.79

GC content: 66.77

Gene sequence:

>927_bases
GTGGATCGATTCGATGCAATGCGGGCGTTTGCGCGCGTGGTCGAGACCGGCAGTTTCACCAAGGCGGCCGAACACCTGCA
CATGAGCCGCGCCAGCGCGACCCAGCTGGTCCAGCAGCTGGAGGCACGCCTGCGGGTGAAGCTGCTCAATCGCACCACGC
GCCGGGTGCAGGTCACTGCCGATGGCGCGGCCTATTACGAGCGCGTGCTGCGCCTGCTGGCAGACATGGACGATGCCGAA
ACCAGCCTGTCCGTTGCAGCCACCTCGCCACGCGGGCGCCTGCGCGTGGACGTGCCCAGCCCGTTGGCGCTGCTGATCCT
GATGCCGGCGCTGCCGGCATTCCATGCGCGTTATCCGCAGATCCAGCTGGACATGGGCGTGAGCGACCGCCGCGTGGATC
TGATCGGCGAAAACGTCGATTGCGTGATACGCGGCGGCACCATCACCGACCAGTCGCTGATTGCGCGTCACGTGGGCGAC
CTGCAGGCCGGCGTGTATGCAGCGCCCGATTACCTGCAGCGGTTGGGCACCCCGACGCACCCGACGGAACTGGAGAATAC
CCGGCATCGCTGCGTCGGCTTCATGCGCTGGGGCAGCAGCACGACCGTGCCGTATGTGATGCAACGCGGCGACGAAGCGG
TGCGCGTGCACGGCCGCCACGTAGTGGCCGCCGACGATGGCAATGCCTATCTGGCCGCCGGTCTGGCCGGCATGGGTGTG
CTGTGGCTGCCGGTGTATATGGCCAACGCGCATGTCGCCAGCGGCGAGCTGGTGCCGATCTTCCAGGACTGGCAGCTGGA
AGCGATGCCGCTGTCGATCGCTTTCCCGCCCAACCGCCATGTCAGCGCCAAGCTGCGAGTATTCATCGATTGGGTGATTG
CACTGATGGCCGAGCATGCGCCAGCGATGGCGCCTGCACCGCGGTGA

Upstream 100 bases:

>100_bases
AATGGAGGCCCACGGTAGGCGCGTGTACGGTGGCGATAAATCGGCAGCATCGACCAACACTGTTTGTAGAATCCAAACAA
TCTTGGCCGCGGGAGCAGTG

Downstream 100 bases:

>100_bases
GCGCCACAGGCATGCGCGCGCTATTGCATCACTTCGCGCCGCACCGGATACCGCCAGCCGCTGATCGCTGCATAGGGCGA
ACGTGCATAAACCCACTGCA

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MDRFDAMRAFARVVETGSFTKAAEHLHMSRASATQLVQQLEARLRVKLLNRTTRRVQVTADGAAYYERVLRLLADMDDAE
TSLSVAATSPRGRLRVDVPSPLALLILMPALPAFHARYPQIQLDMGVSDRRVDLIGENVDCVIRGGTITDQSLIARHVGD
LQAGVYAAPDYLQRLGTPTHPTELENTRHRCVGFMRWGSSTTVPYVMQRGDEAVRVHGRHVVAADDGNAYLAAGLAGMGV
LWLPVYMANAHVASGELVPIFQDWQLEAMPLSIAFPPNRHVSAKLRVFIDWVIALMAEHAPAMAPAPR

Sequences:

>Translated_308_residues
MDRFDAMRAFARVVETGSFTKAAEHLHMSRASATQLVQQLEARLRVKLLNRTTRRVQVTADGAAYYERVLRLLADMDDAE
TSLSVAATSPRGRLRVDVPSPLALLILMPALPAFHARYPQIQLDMGVSDRRVDLIGENVDCVIRGGTITDQSLIARHVGD
LQAGVYAAPDYLQRLGTPTHPTELENTRHRCVGFMRWGSSTTVPYVMQRGDEAVRVHGRHVVAADDGNAYLAAGLAGMGV
LWLPVYMANAHVASGELVPIFQDWQLEAMPLSIAFPPNRHVSAKLRVFIDWVIALMAEHAPAMAPAPR
>Mature_308_residues
MDRFDAMRAFARVVETGSFTKAAEHLHMSRASATQLVQQLEARLRVKLLNRTTRRVQVTADGAAYYERVLRLLADMDDAE
TSLSVAATSPRGRLRVDVPSPLALLILMPALPAFHARYPQIQLDMGVSDRRVDLIGENVDCVIRGGTITDQSLIARHVGD
LQAGVYAAPDYLQRLGTPTHPTELENTRHRCVGFMRWGSSTTVPYVMQRGDEAVRVHGRHVVAADDGNAYLAAGLAGMGV
LWLPVYMANAHVASGELVPIFQDWQLEAMPLSIAFPPNRHVSAKLRVFIDWVIALMAEHAPAMAPAPR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=292, Percent_Identity=36.3013698630137, Blast_Score=187, Evalue=5e-49,
Organism=Escherichia coli, GI145693193, Length=305, Percent_Identity=32.7868852459016, Blast_Score=178, Evalue=3e-46,
Organism=Escherichia coli, GI1787128, Length=286, Percent_Identity=30.0699300699301, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1789639, Length=301, Percent_Identity=29.9003322259136, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1787589, Length=283, Percent_Identity=28.2685512367491, Blast_Score=121, Evalue=7e-29,
Organism=Escherichia coli, GI87081978, Length=306, Percent_Identity=29.4117647058824, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1789440, Length=288, Percent_Identity=26.7361111111111, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1789173, Length=291, Percent_Identity=24.7422680412371, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI157672245, Length=116, Percent_Identity=33.6206896551724, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33920; Mature: 33920

Theoretical pI: Translated: 8.27; Mature: 8.27

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRFDAMRAFARVVETGSFTKAAEHLHMSRASATQLVQQLEARLRVKLLNRTTRRVQVTA
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEE
DGAAYYERVLRLLADMDDAETSLSVAATSPRGRLRVDVPSPLALLILMPALPAFHARYPQ
CCHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCEEEECCCHHHHHHHHHCCHHHHCCCCE
IQLDMGVSDRRVDLIGENVDCVIRGGTITDQSLIARHVGDLQAGVYAAPDYLQRLGTPTH
EEEECCCCCCEEEEECCCEEEEEECCCCCHHHHHHHHHHHHHCCCEECHHHHHHCCCCCC
PTELENTRHRCVGFMRWGSSTTVPYVMQRGDEAVRVHGRHVVAADDGNAYLAAGLAGMGV
CCHHHCCHHHHEEEEEECCCCCCHHHHHCCCCEEEEECCEEEEECCCCEEEEEHHHHCHH
LWLPVYMANAHVASGELVPIFQDWQLEAMPLSIAFPPNRHVSAKLRVFIDWVIALMAEHA
HHHHHHHHCCEECCCCEEEEEECCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCC
PAMAPAPR
CCCCCCCC
>Mature Secondary Structure
MDRFDAMRAFARVVETGSFTKAAEHLHMSRASATQLVQQLEARLRVKLLNRTTRRVQVTA
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEE
DGAAYYERVLRLLADMDDAETSLSVAATSPRGRLRVDVPSPLALLILMPALPAFHARYPQ
CCHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCEEEECCCHHHHHHHHHCCHHHHCCCCE
IQLDMGVSDRRVDLIGENVDCVIRGGTITDQSLIARHVGDLQAGVYAAPDYLQRLGTPTH
EEEECCCCCCEEEEECCCEEEEEECCCCCHHHHHHHHHHHHHCCCEECHHHHHHCCCCCC
PTELENTRHRCVGFMRWGSSTTVPYVMQRGDEAVRVHGRHVVAADDGNAYLAAGLAGMGV
CCHHHCCHHHHEEEEEECCCCCCHHHHHCCCCEEEEECCEEEEECCCCEEEEEHHHHCHH
LWLPVYMANAHVASGELVPIFQDWQLEAMPLSIAFPPNRHVSAKLRVFIDWVIALMAEHA
HHHHHHHHCCEECCCCEEEEEECCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCC
PAMAPAPR
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]