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The map label for this gene is galE [H]

Identifier: 21244465

GI number: 21244465

Start: 4414820

End: 4415989

Strand: Direct

Name: galE [H]

Synonym: XAC3740

Alternate gene names: 21244465

Gene position: 4414820-4415989 (Clockwise)

Preceding gene: 21244464

Following gene: 21244466

Centisome position: 85.3

GC content: 65.3

Gene sequence:

>1170_bases
ATGAGAATTCTGGTCACCGGCGGCACCGGCTATATCGGCTCGCACACCTGCGTGGAACTGGCGCAGCGTGGGCACGAAGT
GTGCATTGTCGATAATTTGAGCAACTCCTCCGAACGCGTGCTCGACCATCTGCAGCATCTGATGGGATTTCGCCCGGAGT
TTCATCGCATGGATGTGCGTGCGCCCGAGCTTGCCGATTTACTGATCGGCAAGCGCATCGACGCCGTCCTGCATTTTGCC
GCGCTCAAGGCCGTTGGCGAATCGGTGCGCGAGCCGCTGCTGTACTTCAACAACAATGTCACCGGCACGCTGGCGCTGCT
GCGCGCGATGCGGACTGCCAAGGTGTGCAACCTGGTATTCAGTTCTTCGGCCACCGTGTATGGCGACGCCAACCGCAGCC
CGATCGACGAAAGCGCGCCACTGAAGGCGATCAACCCCTACGGGCGCACCAAGCTGATGATGGAAGAAATGATCGGCGAC
CTCAGCGCCGCCTGGCCGGATTTCAACGCGGCGTTGCTGCGCTACTTCAACCCGGTGGGTGCGCACCCGAGCGGATATCT
GGGCGAAGACCCGCGAGGAGTACCGAACAACCTGATGCCCTACATCGCACAGGTGGCAGTGGGGCGTCGCGAGGCACTGC
AGGTTTTCGGCGACGACTATCCGACCGACGACGGCACCGGCGTGCGCGACTATCTGCATGTGATGGATCTGGCGCGCGCA
CATGTGGACGCCATCGATTACCTGCAGCGCCAGCGCAAGGGCTTGGTGGTCAATCTGGGCACCGGGCGTGGCTACAGCGT
GCGCGAGGTGGCGGCCGCGTTCGCGCGCGCCAGTGGCAGGCGCATTCCGCTGAGCATCGCGCCGCGTCGCGATGGCGATG
TGGCGGTGTACTTCGCCAGCACCGCGCTGGCCAACCGGCTGCTGGGCTGGACCGCGGAATACGACCTGGACCGCATGTGT
CGCGACACCTGGCGTTGGCAGTCGATGTATCCGGATGGCTATGCCGGTTCGCGTTTGCCGCGCCCGCGCACCGCGGCGGC
CGTGCCAGAGCGCGAAGGTGCGCGCGAGCTGCCGGCACCAGCGCCCCGGCTATCGCCCGGCCCGGACACGCGCCGTCGCA
GCGAGCCGGTAAGCACGCTCGTGGTCGCCACTGGCTTTTCCCGCGTGTAA

Upstream 100 bases:

>100_bases
TGGCGTGACGACATCACCCCACGCGCATCGAAGCATACGACGTGATGCATCCGCGCCATCGGCAGGCCAGCGCAGTAGCG
CCCCTATAAGGCAGACGACA

Downstream 100 bases:

>100_bases
TACGCAACGACCCGTTTCTTTCCTACGAGGGCATTCCATGAGTTGGGCTGGTCAGTTCCAATACGCGATCGGCAAGACCC
GCCGCGCGGTTCCATCCGAC

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MRILVTGGTGYIGSHTCVELAQRGHEVCIVDNLSNSSERVLDHLQHLMGFRPEFHRMDVRAPELADLLIGKRIDAVLHFA
ALKAVGESVREPLLYFNNNVTGTLALLRAMRTAKVCNLVFSSSATVYGDANRSPIDESAPLKAINPYGRTKLMMEEMIGD
LSAAWPDFNAALLRYFNPVGAHPSGYLGEDPRGVPNNLMPYIAQVAVGRREALQVFGDDYPTDDGTGVRDYLHVMDLARA
HVDAIDYLQRQRKGLVVNLGTGRGYSVREVAAAFARASGRRIPLSIAPRRDGDVAVYFASTALANRLLGWTAEYDLDRMC
RDTWRWQSMYPDGYAGSRLPRPRTAAAVPEREGARELPAPAPRLSPGPDTRRRSEPVSTLVVATGFSRV

Sequences:

>Translated_389_residues
MRILVTGGTGYIGSHTCVELAQRGHEVCIVDNLSNSSERVLDHLQHLMGFRPEFHRMDVRAPELADLLIGKRIDAVLHFA
ALKAVGESVREPLLYFNNNVTGTLALLRAMRTAKVCNLVFSSSATVYGDANRSPIDESAPLKAINPYGRTKLMMEEMIGD
LSAAWPDFNAALLRYFNPVGAHPSGYLGEDPRGVPNNLMPYIAQVAVGRREALQVFGDDYPTDDGTGVRDYLHVMDLARA
HVDAIDYLQRQRKGLVVNLGTGRGYSVREVAAAFARASGRRIPLSIAPRRDGDVAVYFASTALANRLLGWTAEYDLDRMC
RDTWRWQSMYPDGYAGSRLPRPRTAAAVPEREGARELPAPAPRLSPGPDTRRRSEPVSTLVVATGFSRV
>Mature_389_residues
MRILVTGGTGYIGSHTCVELAQRGHEVCIVDNLSNSSERVLDHLQHLMGFRPEFHRMDVRAPELADLLIGKRIDAVLHFA
ALKAVGESVREPLLYFNNNVTGTLALLRAMRTAKVCNLVFSSSATVYGDANRSPIDESAPLKAINPYGRTKLMMEEMIGD
LSAAWPDFNAALLRYFNPVGAHPSGYLGEDPRGVPNNLMPYIAQVAVGRREALQVFGDDYPTDDGTGVRDYLHVMDLARA
HVDAIDYLQRQRKGLVVNLGTGRGYSVREVAAAFARASGRRIPLSIAPRRDGDVAVYFASTALANRLLGWTAEYDLDRMC
RDTWRWQSMYPDGYAGSRLPRPRTAAAVPEREGARELPAPAPRLSPGPDTRRRSEPVSTLVVATGFSRV

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=342, Percent_Identity=52.6315789473684, Blast_Score=360, Evalue=1e-99,
Organism=Homo sapiens, GI56118217, Length=342, Percent_Identity=52.6315789473684, Blast_Score=360, Evalue=1e-99,
Organism=Homo sapiens, GI189083684, Length=342, Percent_Identity=52.6315789473684, Blast_Score=360, Evalue=1e-99,
Organism=Homo sapiens, GI7657641, Length=275, Percent_Identity=26.9090909090909, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI42516563, Length=314, Percent_Identity=26.4331210191083, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1786974, Length=336, Percent_Identity=56.547619047619, Blast_Score=385, Evalue=1e-108,
Organism=Escherichia coli, GI48994969, Length=260, Percent_Identity=27.3076923076923, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI71982038, Length=348, Percent_Identity=46.551724137931, Blast_Score=319, Evalue=1e-87,
Organism=Caenorhabditis elegans, GI71982035, Length=346, Percent_Identity=47.3988439306358, Blast_Score=319, Evalue=2e-87,
Organism=Caenorhabditis elegans, GI17539532, Length=278, Percent_Identity=25.5395683453237, Blast_Score=69, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6319493, Length=342, Percent_Identity=48.5380116959064, Blast_Score=323, Evalue=2e-89,
Organism=Drosophila melanogaster, GI19923002, Length=343, Percent_Identity=50.7288629737609, Blast_Score=343, Evalue=8e-95,
Organism=Drosophila melanogaster, GI21356223, Length=321, Percent_Identity=25.5451713395639, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 42848; Mature: 42848

Theoretical pI: Translated: 8.80; Mature: 8.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILVTGGTGYIGSHTCVELAQRGHEVCIVDNLSNSSERVLDHLQHLMGFRPEFHRMDVR
CEEEEECCCCCCCCHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCHHHCCCC
APELADLLIGKRIDAVLHFAALKAVGESVREPLLYFNNNVTGTLALLRAMRTAKVCNLVF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHHHH
SSSATVYGDANRSPIDESAPLKAINPYGRTKLMMEEMIGDLSAAWPDFNAALLRYFNPVG
CCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCC
AHPSGYLGEDPRGVPNNLMPYIAQVAVGRREALQVFGDDYPTDDGTGVRDYLHVMDLARA
CCCCCCCCCCCCCCCCHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
HVDAIDYLQRQRKGLVVNLGTGRGYSVREVAAAFARASGRRIPLSIAPRRDGDVAVYFAS
HHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEECCCCCCCEEEEEHH
TALANRLLGWTAEYDLDRMCRDTWRWQSMYPDGYAGSRLPRPRTAAAVPEREGARELPAP
HHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
APRLSPGPDTRRRSEPVSTLVVATGFSRV
CCCCCCCCCCHHCCCCHHEEEEECCCCCC
>Mature Secondary Structure
MRILVTGGTGYIGSHTCVELAQRGHEVCIVDNLSNSSERVLDHLQHLMGFRPEFHRMDVR
CEEEEECCCCCCCCHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCHHHCCCC
APELADLLIGKRIDAVLHFAALKAVGESVREPLLYFNNNVTGTLALLRAMRTAKVCNLVF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHHHH
SSSATVYGDANRSPIDESAPLKAINPYGRTKLMMEEMIGDLSAAWPDFNAALLRYFNPVG
CCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCC
AHPSGYLGEDPRGVPNNLMPYIAQVAVGRREALQVFGDDYPTDDGTGVRDYLHVMDLARA
CCCCCCCCCCCCCCCCHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
HVDAIDYLQRQRKGLVVNLGTGRGYSVREVAAAFARASGRRIPLSIAPRRDGDVAVYFAS
HHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEECCCCCCCEEEEEHH
TALANRLLGWTAEYDLDRMCRDTWRWQSMYPDGYAGSRLPRPRTAAAVPEREGARELPAP
HHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
APRLSPGPDTRRRSEPVSTLVVATGFSRV
CCCCCCCCCCHHCCCCHHEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3022232; 8905232; 9278503; 2134186; 8564363; 6301942; 1579570; 8611559; 8931134; 9174344; 9271499; 9708982 [H]