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The map label for this gene is ntrC [H]

Identifier: 21244458

GI number: 21244458

Start: 4407382

End: 4408695

Strand: Reverse

Name: ntrC [H]

Synonym: XAC3733

Alternate gene names: 21244458

Gene position: 4408695-4407382 (Counterclockwise)

Preceding gene: 21244462

Following gene: 21244457

Centisome position: 85.18

GC content: 64.38

Gene sequence:

>1314_bases
ATGTATCAGTCATTGCGGACAGAAGCGCTCATGGACCGTCTTTCCTGCGCCATCATCGACGACGACGTGGAGTTCTGCGA
TCAGGTGGTTGAACTTGCCACCGATAGCGGCTTCCATGCCAAGGGCATTCACACCCTTGGCGAAGCCAGCCGCTGGCTGG
ACATCAACTTTCCCGACCTGTTGGTAGTGGATGTTGGCCTGCCAGACGGCAGCGGTTTCGATCTGATCGAACGGCTCGAC
CCGGACCACACCCCGCAAATCGTTGTGGTGTCGGGCGATTACGCGCGCGAAACCCAGGGCCGCGCCCAGCAGTTCGGGGT
CAGCGAATTCCTGACCAAGCCGTTCGCGCCCGAACGCCTGGAACGGGTGCTCGGGGGACTGCGCGAAGCGCAACAGGGCA
ACCTGGGCATCGTCGGCAACAGCGACAGCATCGTCATGCTGCGCAAGGACATAGTGCGCGTGGCGCCGACCGATCTGAAT
GTACTGGTGACCGGCGAAACCGGCACCGGCAAGGATCTGGTGGCGCGCGCCATCCACCGTGTGTCCGGTCGCCGCGGACG
CTTCGTACCGGTCAATTGCGGGGCCATTCCGGAGGAGCTGCTGGCCAGCCAGTTGTTCGGCCACGAGCGCGGCAGCTTCA
CCGGCGCCGACCGTCGGCATGCCGGGTTCCTGGAGCAGGCCGCAGACGGCACGCTGTTCCTGGATGAAATCGGCGAGATG
CCCAAGCGGCTGCAGGTGTATCTGCTGCGGGCGATCGAATCGCGCAGCTTCATGCGCGTGGGCGGCAACGAGGAAATCGC
ACTGGATGCGCGCGTGGTGGCAGCCACCCATCAGCACGTGCAGCGCGAGCAGGCGGTGCTGCGCGAAGACCTGTTCTACC
GTCTCAACGAATACCCGATCCAGGTGCCGCCGCTGCGCGAGCGCCGCGGCGACGCGCGCCTGCTTGGCTTGCGCGCGATC
GACGAGCTCAACGCCAAATACGGCAAGCGCAAGTTGCCGACCAAATCGTTGCTGCGCTACCTGGCCTACCATGCCTGGCC
GGGCAATGTGCGCGAGCTGCGCTCGTTCATCCACTATCTGTATCTGCGCTCCGATGGCGATCTGTTGAGCGCTCCGGATG
TGGAGCAGACCGTGCCGCAGGCCGATCAGGACGGCTTGCTCATTCCTGCCGGCTGGACCATGCGCCAGGCCGAAGACGCG
ATGATCGAATCGGCACTGGCGCGTACGCGCTTCAACAAAAAGGCCGCCGCGCGCGAACTGGGCATCAGCGTGCGCACCTT
GCATAACCGGCTCAGCGACAAGGACGCGGAGTGA

Upstream 100 bases:

>100_bases
GGAAGGGCGCCGCATCATTCACAGAGCGTGACAGCAACAGGCAATTTCCGATGTGGTGTGTCAGCGCATTTCGCGCGGCC
CTCACAATTCTCAACTGAAC

Downstream 100 bases:

>100_bases
GCGACGCACCGCGTGGGCAGCGGCGCGAGTTGCTGCACCAGTTGCGCAACCGTCTCAACGTGATGGGCTTTGCGTTGTAT
GCGTTGCGCAACGAGAGGTC

Product: NtrC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MYQSLRTEALMDRLSCAIIDDDVEFCDQVVELATDSGFHAKGIHTLGEASRWLDINFPDLLVVDVGLPDGSGFDLIERLD
PDHTPQIVVVSGDYARETQGRAQQFGVSEFLTKPFAPERLERVLGGLREAQQGNLGIVGNSDSIVMLRKDIVRVAPTDLN
VLVTGETGTGKDLVARAIHRVSGRRGRFVPVNCGAIPEELLASQLFGHERGSFTGADRRHAGFLEQAADGTLFLDEIGEM
PKRLQVYLLRAIESRSFMRVGGNEEIALDARVVAATHQHVQREQAVLREDLFYRLNEYPIQVPPLRERRGDARLLGLRAI
DELNAKYGKRKLPTKSLLRYLAYHAWPGNVRELRSFIHYLYLRSDGDLLSAPDVEQTVPQADQDGLLIPAGWTMRQAEDA
MIESALARTRFNKKAAARELGISVRTLHNRLSDKDAE

Sequences:

>Translated_437_residues
MYQSLRTEALMDRLSCAIIDDDVEFCDQVVELATDSGFHAKGIHTLGEASRWLDINFPDLLVVDVGLPDGSGFDLIERLD
PDHTPQIVVVSGDYARETQGRAQQFGVSEFLTKPFAPERLERVLGGLREAQQGNLGIVGNSDSIVMLRKDIVRVAPTDLN
VLVTGETGTGKDLVARAIHRVSGRRGRFVPVNCGAIPEELLASQLFGHERGSFTGADRRHAGFLEQAADGTLFLDEIGEM
PKRLQVYLLRAIESRSFMRVGGNEEIALDARVVAATHQHVQREQAVLREDLFYRLNEYPIQVPPLRERRGDARLLGLRAI
DELNAKYGKRKLPTKSLLRYLAYHAWPGNVRELRSFIHYLYLRSDGDLLSAPDVEQTVPQADQDGLLIPAGWTMRQAEDA
MIESALARTRFNKKAAARELGISVRTLHNRLSDKDAE
>Mature_437_residues
MYQSLRTEALMDRLSCAIIDDDVEFCDQVVELATDSGFHAKGIHTLGEASRWLDINFPDLLVVDVGLPDGSGFDLIERLD
PDHTPQIVVVSGDYARETQGRAQQFGVSEFLTKPFAPERLERVLGGLREAQQGNLGIVGNSDSIVMLRKDIVRVAPTDLN
VLVTGETGTGKDLVARAIHRVSGRRGRFVPVNCGAIPEELLASQLFGHERGSFTGADRRHAGFLEQAADGTLFLDEIGEM
PKRLQVYLLRAIESRSFMRVGGNEEIALDARVVAATHQHVQREQAVLREDLFYRLNEYPIQVPPLRERRGDARLLGLRAI
DELNAKYGKRKLPTKSLLRYLAYHAWPGNVRELRSFIHYLYLRSDGDLLSAPDVEQTVPQADQDGLLIPAGWTMRQAEDA
MIESALARTRFNKKAAARELGISVRTLHNRLSDKDAE

Specific function: Member of the two-component regulatory system ntrB/ntrC involved in the activation of nitrogen assimilatory genes such as glnA. NtrC is phosphorylated by ntrB and interacts with sigma-54 [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=444, Percent_Identity=35.1351351351351, Blast_Score=227, Evalue=1e-60,
Organism=Escherichia coli, GI1788550, Length=406, Percent_Identity=34.4827586206897, Blast_Score=221, Evalue=5e-59,
Organism=Escherichia coli, GI1789233, Length=315, Percent_Identity=40.6349206349206, Blast_Score=212, Evalue=3e-56,
Organism=Escherichia coli, GI1790299, Length=468, Percent_Identity=32.0512820512821, Blast_Score=207, Evalue=1e-54,
Organism=Escherichia coli, GI1789087, Length=308, Percent_Identity=40.5844155844156, Blast_Score=199, Evalue=4e-52,
Organism=Escherichia coli, GI1788905, Length=431, Percent_Identity=33.1786542923434, Blast_Score=195, Evalue=5e-51,
Organism=Escherichia coli, GI87082117, Length=282, Percent_Identity=41.4893617021277, Blast_Score=191, Evalue=9e-50,
Organism=Escherichia coli, GI1786524, Length=321, Percent_Identity=40.4984423676012, Blast_Score=186, Evalue=2e-48,
Organism=Escherichia coli, GI87082152, Length=322, Percent_Identity=39.1304347826087, Blast_Score=185, Evalue=6e-48,
Organism=Escherichia coli, GI87081872, Length=307, Percent_Identity=34.5276872964169, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1787583, Length=318, Percent_Identity=33.9622641509434, Blast_Score=151, Evalue=1e-37,
Organism=Escherichia coli, GI1789828, Length=209, Percent_Identity=33.4928229665072, Blast_Score=108, Evalue=7e-25,
Organism=Escherichia coli, GI87081858, Length=225, Percent_Identity=33.3333333333333, Blast_Score=102, Evalue=5e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR010114
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 48771; Mature: 48771

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00675 SIGMA54_INTERACT_1 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYQSLRTEALMDRLSCAIIDDDVEFCDQVVELATDSGFHAKGIHTLGEASRWLDINFPDL
CCCHHHHHHHHHHHHHEEECCHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCEEECCCCCE
LVVDVGLPDGSGFDLIERLDPDHTPQIVVVSGDYARETQGRAQQFGVSEFLTKPFAPERL
EEEEECCCCCCCCHHHHHCCCCCCCEEEEEECCCHHHHCCHHHHCCHHHHHHCCCCHHHH
ERVLGGLREAQQGNLGIVGNSDSIVMLRKDIVRVAPTDLNVLVTGETGTGKDLVARAIHR
HHHHHHHHHHCCCCEEEEECCCCEEEEEHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHH
VSGRRGRFVPVNCGAIPEELLASQLFGHERGSFTGADRRHAGFLEQAADGTLFLDEIGEM
HCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCEEHHHHHCC
PKRLQVYLLRAIESRSFMRVGGNEEIALDARVVAATHQHVQREQAVLREDLFYRLNEYPI
HHHHHHHHHHHHHCCCEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
QVPPLRERRGDARLLGLRAIDELNAKYGKRKLPTKSLLRYLAYHAWPGNVRELRSFIHYL
CCCCHHHCCCCCEEEHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHH
YLRSDGDLLSAPDVEQTVPQADQDGLLIPAGWTMRQAEDAMIESALARTRFNKKAAAREL
HCCCCCCCCCCCCHHHHCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GISVRTLHNRLSDKDAE
CCHHHHHHHHHCCCCCC
>Mature Secondary Structure
MYQSLRTEALMDRLSCAIIDDDVEFCDQVVELATDSGFHAKGIHTLGEASRWLDINFPDL
CCCHHHHHHHHHHHHHEEECCHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCEEECCCCCE
LVVDVGLPDGSGFDLIERLDPDHTPQIVVVSGDYARETQGRAQQFGVSEFLTKPFAPERL
EEEEECCCCCCCCHHHHHCCCCCCCEEEEEECCCHHHHCCHHHHCCHHHHHHCCCCHHHH
ERVLGGLREAQQGNLGIVGNSDSIVMLRKDIVRVAPTDLNVLVTGETGTGKDLVARAIHR
HHHHHHHHHHCCCCEEEEECCCCEEEEEHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHH
VSGRRGRFVPVNCGAIPEELLASQLFGHERGSFTGADRRHAGFLEQAADGTLFLDEIGEM
HCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCEEHHHHHCC
PKRLQVYLLRAIESRSFMRVGGNEEIALDARVVAATHQHVQREQAVLREDLFYRLNEYPI
HHHHHHHHHHHHHCCCEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
QVPPLRERRGDARLLGLRAIDELNAKYGKRKLPTKSLLRYLAYHAWPGNVRELRSFIHYL
CCCCHHHCCCCCEEEHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHH
YLRSDGDLLSAPDVEQTVPQADQDGLLIPAGWTMRQAEDAMIESALARTRFNKKAAAREL
HCCCCCCCCCCCCHHHHCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GISVRTLHNRLSDKDAE
CCHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1661370 [H]