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The map label for this gene is evgS [H]

Identifier: 21244408

GI number: 21244408

Start: 4360048

End: 4361943

Strand: Reverse

Name: evgS [H]

Synonym: XAC3683

Alternate gene names: 21244408

Gene position: 4361943-4360048 (Counterclockwise)

Preceding gene: 21244409

Following gene: 21244407

Centisome position: 84.28

GC content: 65.77

Gene sequence:

>1896_bases
ATGGTGTTCGACGGCGAGCAGGCGGTGGACTATGTGATCCGCACCACCAATGGCGCCTTCGAGCGCTATACCGGTCTGTC
GCCCAACGCACTGAACGTCTCCATCCGCAACCTGCTCCCCGAACACGAGCAGGAATGGTTCGACCGCTATGGTCACGTTG
CGCGCACCGGCAACCGCATCCACTTCGAAATGCAGGCCAAGGCGCTCAAGCGCTGGTATTCGGTGGATGCGTTCCGGGTC
GGGCAGCCGGAGCAGGCGCGGGTGGCGATCCTGTTCATGGACATCACCGAGCGCAAACGCGTCGAGCGCGAGCTGGCCGA
AAGCGAGGCGCGTTTCAGTGCGCTGGCCGACGGCTTGCCGATGCCGGTGTGGGTGCTGGACGCGCAGGGCGTGGTGCGCT
TCGTCAACAGCGCGTATGGCGAATTCTTTGGCCTGGATATCTCCAGCGGTACGGTGTCGGCGTGGAGCGAACTGCTGCAT
CCGGACGACTTGCCGACCTTCCAGTTCGAGCTGGCGGCATCGCTGCAGGAACAGCGCGGCCTGCGCGCGCTGGTGCGCGC
GCGCCGCCATGATGGGCAGTGGCGCTGGATCGAAATGACCGCCACCCCGCGCTATTCGGCCGACGGCCGTTTCATCGGCC
TGGCCGGCAGCAGCCCGGACGTGACCGAGCAGCGCGAGATCGAACTGGCGCGCGAGCAATTGCTGGAGTCCGAGCGCAGC
GCGCGCAACGAGGCCGAAAGCATGGCGCGGCTGAAGGACGAGTTCCTGGCCACGCTGTCGCACGAACTGCGCACCCCGCT
GACCACCATCCTGGGCTGGAGCGAGTTGCTGCTGCAGCGGGTCGAAGAAGGCCAGCCCTACTACAAGGGGCTGTCGGTGA
TCGCCAGCAGCGCACGTGCGCAGAAGCGGCTGATTTCCGACATGCTCGATCTCAGCAGCATGTTGCTGGGCAAGGTGCAG
CTGGAAGTCGAATCGCTGGATCTGGTCGAGCAGGTGCGCGAAGCCTTGAATACCCAGGAACTGGCTGCCGAAGGCAAGGA
CCAGGTCCTGGAGCTGCATGTGCCGCCCACGCCGTGCCTGGTGCTTGGCGATGCCACGCGCCTGCAGCAGGTGTTGTGGA
ACTTGCTGTCCAACGCGATCAAGTTCACCCCGGCACATGGTCGTATCGACGTCAAGATCGAGCGCGACGACGGGCATCTG
GTGGTATCGGTCTGCGACTCCGGCGATGGCATTGCAGCGGAATTCCTGCCGCATCTGTTCGGCCGTTTCCGCCAGGCCGA
CGGCACCACCACGCGCCAGCATGGCGGCCTTGGTCTGGGCCTGGCCATCGTGCAACAGCTGGTGGAAATGCACGGCGGCC
AGGTCGGTGCCACCAGTGGCGGCCGTGGCAAGGGCGCGACCTTCACCGTGCGGCTGCCGGAACACGTTCCCGATCAGGCC
AAGCGCCCACGCCGCGAATTGCGGCGGCGTCTGATGTCCGAACAGATCGTCGAAGCGCGCGCGCTCAACGGTCTGCGCCT
GCTGGCGGTCGAAGACCAACCGGACATGCTCGATTATCTGCGGCGTCTGCTCGAAGAGCAGGGCGCCGAAGTGGTCACCG
CCGGCAGCGCCACCGATGCGCTGGCATTGATCGATCATCGTGGCCACGCGCGCTTCGATCTGATGCTGACCGATATCGGC
ATGCCGGGCATGGACGGTTACGGCTTGATCCGCACGGTGCGCGAAAACCTCGGGTTGACTGCTACCGCGTTGCCGGCCGT
GGCAGTCACCGCCCTGGCCCGCGAAGACGATCGCAAGCGCGCGCTGGAGTCCGGGTTTCAGGAACATCTGGCCAAGCCCT
ACAGCGTGGCGCAGCTGGTCACGGCCGTGCGTGCCGCCCGCCAGGCGGTGGAGTAA

Upstream 100 bases:

>100_bases
GGCTGCCGCACTGCCGGCCGCCATCGCCGAGCCGTTTCTGGACCCGGCGATGTATCACGAGATTTTCCACAACATCGACG
CCGGGTTTTGCGTCATCGAC

Downstream 100 bases:

>100_bases
CCGGCGCGCGGCGGTACGGCCGCGCATCGGGTGATGGCAACGTGGGTGAGGCGACGCGTTGGATACGCAGTAGCGCGTAT
GGGTTGGGTACTACTGGGCG

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 631; Mature: 631

Protein sequence:

>631_residues
MVFDGEQAVDYVIRTTNGAFERYTGLSPNALNVSIRNLLPEHEQEWFDRYGHVARTGNRIHFEMQAKALKRWYSVDAFRV
GQPEQARVAILFMDITERKRVERELAESEARFSALADGLPMPVWVLDAQGVVRFVNSAYGEFFGLDISSGTVSAWSELLH
PDDLPTFQFELAASLQEQRGLRALVRARRHDGQWRWIEMTATPRYSADGRFIGLAGSSPDVTEQREIELAREQLLESERS
ARNEAESMARLKDEFLATLSHELRTPLTTILGWSELLLQRVEEGQPYYKGLSVIASSARAQKRLISDMLDLSSMLLGKVQ
LEVESLDLVEQVREALNTQELAAEGKDQVLELHVPPTPCLVLGDATRLQQVLWNLLSNAIKFTPAHGRIDVKIERDDGHL
VVSVCDSGDGIAAEFLPHLFGRFRQADGTTTRQHGGLGLGLAIVQQLVEMHGGQVGATSGGRGKGATFTVRLPEHVPDQA
KRPRRELRRRLMSEQIVEARALNGLRLLAVEDQPDMLDYLRRLLEEQGAEVVTAGSATDALALIDHRGHARFDLMLTDIG
MPGMDGYGLIRTVRENLGLTATALPAVAVTALAREDDRKRALESGFQEHLAKPYSVAQLVTAVRAARQAVE

Sequences:

>Translated_631_residues
MVFDGEQAVDYVIRTTNGAFERYTGLSPNALNVSIRNLLPEHEQEWFDRYGHVARTGNRIHFEMQAKALKRWYSVDAFRV
GQPEQARVAILFMDITERKRVERELAESEARFSALADGLPMPVWVLDAQGVVRFVNSAYGEFFGLDISSGTVSAWSELLH
PDDLPTFQFELAASLQEQRGLRALVRARRHDGQWRWIEMTATPRYSADGRFIGLAGSSPDVTEQREIELAREQLLESERS
ARNEAESMARLKDEFLATLSHELRTPLTTILGWSELLLQRVEEGQPYYKGLSVIASSARAQKRLISDMLDLSSMLLGKVQ
LEVESLDLVEQVREALNTQELAAEGKDQVLELHVPPTPCLVLGDATRLQQVLWNLLSNAIKFTPAHGRIDVKIERDDGHL
VVSVCDSGDGIAAEFLPHLFGRFRQADGTTTRQHGGLGLGLAIVQQLVEMHGGQVGATSGGRGKGATFTVRLPEHVPDQA
KRPRRELRRRLMSEQIVEARALNGLRLLAVEDQPDMLDYLRRLLEEQGAEVVTAGSATDALALIDHRGHARFDLMLTDIG
MPGMDGYGLIRTVRENLGLTATALPAVAVTALAREDDRKRALESGFQEHLAKPYSVAQLVTAVRAARQAVE
>Mature_631_residues
MVFDGEQAVDYVIRTTNGAFERYTGLSPNALNVSIRNLLPEHEQEWFDRYGHVARTGNRIHFEMQAKALKRWYSVDAFRV
GQPEQARVAILFMDITERKRVERELAESEARFSALADGLPMPVWVLDAQGVVRFVNSAYGEFFGLDISSGTVSAWSELLH
PDDLPTFQFELAASLQEQRGLRALVRARRHDGQWRWIEMTATPRYSADGRFIGLAGSSPDVTEQREIELAREQLLESERS
ARNEAESMARLKDEFLATLSHELRTPLTTILGWSELLLQRVEEGQPYYKGLSVIASSARAQKRLISDMLDLSSMLLGKVQ
LEVESLDLVEQVREALNTQELAAEGKDQVLELHVPPTPCLVLGDATRLQQVLWNLLSNAIKFTPAHGRIDVKIERDDGHL
VVSVCDSGDGIAAEFLPHLFGRFRQADGTTTRQHGGLGLGLAIVQQLVEMHGGQVGATSGGRGKGATFTVRLPEHVPDQA
KRPRRELRRRLMSEQIVEARALNGLRLLAVEDQPDMLDYLRRLLEEQGAEVVTAGSATDALALIDHRGHARFDLMLTDIG
MPGMDGYGLIRTVRENLGLTATALPAVAVTALAREDDRKRALESGFQEHLAKPYSVAQLVTAVRAARQAVE

Specific function: Member of the two-component regulatory system evgS/evgA. Phosphorylates evgA via a four-step phosphorelay in response to environmental signals [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=560, Percent_Identity=28.9285714285714, Blast_Score=174, Evalue=2e-44,
Organism=Escherichia coli, GI48994928, Length=556, Percent_Identity=29.8561151079137, Blast_Score=169, Evalue=6e-43,
Organism=Escherichia coli, GI87081816, Length=350, Percent_Identity=32.8571428571429, Blast_Score=138, Evalue=1e-33,
Organism=Escherichia coli, GI1789149, Length=236, Percent_Identity=38.9830508474576, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI145693157, Length=248, Percent_Identity=36.6935483870968, Blast_Score=119, Evalue=8e-28,
Organism=Escherichia coli, GI1786912, Length=248, Percent_Identity=34.2741935483871, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1786783, Length=251, Percent_Identity=31.8725099601594, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1790436, Length=248, Percent_Identity=31.4516129032258, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI1786600, Length=382, Percent_Identity=28.0104712041885, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI1788393, Length=255, Percent_Identity=29.4117647058824, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI1790346, Length=228, Percent_Identity=31.140350877193, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1788279, Length=222, Percent_Identity=28.3783783783784, Blast_Score=86, Evalue=9e-18,
Organism=Escherichia coli, GI1788549, Length=286, Percent_Identity=30.0699300699301, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI1790861, Length=235, Percent_Identity=32.7659574468085, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI87082128, Length=268, Percent_Identity=27.6119402985075, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1790551, Length=232, Percent_Identity=29.7413793103448, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI87082012, Length=121, Percent_Identity=33.0578512396694, Blast_Score=68, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322044, Length=149, Percent_Identity=30.8724832214765, Blast_Score=67, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001638
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00072 Response_reg; PF00497 SBP_bac_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 70230; Mature: 70230

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVFDGEQAVDYVIRTTNGAFERYTGLSPNALNVSIRNLLPEHEQEWFDRYGHVARTGNRI
CCCCCHHHHHHHEECCCCCHHHHCCCCCCCEEEEHHHHCCHHHHHHHHHHCCHHCCCCEE
HFEMQAKALKRWYSVDAFRVGQPEQARVAILFMDITERKRVERELAESEARFSALADGLP
EEEHHHHHHHHHHCCCCEECCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCC
MPVWVLDAQGVVRFVNSAYGEFFGLDISSGTVSAWSELLHPDDLPTFQFELAASLQEQRG
CCEEEECHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
LRALVRARRHDGQWRWIEMTATPRYSADGRFIGLAGSSPDVTEQREIELAREQLLESERS
HHHHHHHHHCCCCEEEEEEEECCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHH
ARNEAESMARLKDEFLATLSHELRTPLTTILGWSELLLQRVEEGQPYYKGLSVIASSARA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
QKRLISDMLDLSSMLLGKVQLEVESLDLVEQVREALNTQELAAEGKDQVLELHVPPTPCL
HHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHCHHHHHHCCCCCEEEEECCCCCEE
VLGDATRLQQVLWNLLSNAIKFTPAHGRIDVKIERDDGHLVVSVCDSGDGIAAEFLPHLF
EECCHHHHHHHHHHHHHHHEEECCCCCEEEEEEEECCCEEEEEEECCCCCHHHHHHHHHH
GRFRQADGTTTRQHGGLGLGLAIVQQLVEMHGGQVGATSGGRGKGATFTVRLPEHVPDQA
HHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCEEEEECCCCCCCHH
KRPRRELRRRLMSEQIVEARALNGLRLLAVEDQPDMLDYLRRLLEEQGAEVVTAGSATDA
HHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCCEEEECCCCCCH
LALIDHRGHARFDLMLTDIGMPGMDGYGLIRTVRENLGLTATALPAVAVTALAREDDRKR
HHEEECCCCCEEEEEEEECCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCHHHHH
ALESGFQEHLAKPYSVAQLVTAVRAARQAVE
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVFDGEQAVDYVIRTTNGAFERYTGLSPNALNVSIRNLLPEHEQEWFDRYGHVARTGNRI
CCCCCHHHHHHHEECCCCCHHHHCCCCCCCEEEEHHHHCCHHHHHHHHHHCCHHCCCCEE
HFEMQAKALKRWYSVDAFRVGQPEQARVAILFMDITERKRVERELAESEARFSALADGLP
EEEHHHHHHHHHHCCCCEECCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCC
MPVWVLDAQGVVRFVNSAYGEFFGLDISSGTVSAWSELLHPDDLPTFQFELAASLQEQRG
CCEEEECHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
LRALVRARRHDGQWRWIEMTATPRYSADGRFIGLAGSSPDVTEQREIELAREQLLESERS
HHHHHHHHHCCCCEEEEEEEECCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHH
ARNEAESMARLKDEFLATLSHELRTPLTTILGWSELLLQRVEEGQPYYKGLSVIASSARA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
QKRLISDMLDLSSMLLGKVQLEVESLDLVEQVREALNTQELAAEGKDQVLELHVPPTPCL
HHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHCHHHHHHCCCCCEEEEECCCCCEE
VLGDATRLQQVLWNLLSNAIKFTPAHGRIDVKIERDDGHLVVSVCDSGDGIAAEFLPHLF
EECCHHHHHHHHHHHHHHHEEECCCCCEEEEEEEECCCEEEEEEECCCCCHHHHHHHHHH
GRFRQADGTTTRQHGGLGLGLAIVQQLVEMHGGQVGATSGGRGKGATFTVRLPEHVPDQA
HHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCEEEEECCCCCCCHH
KRPRRELRRRLMSEQIVEARALNGLRLLAVEDQPDMLDYLRRLLEEQGAEVVTAGSATDA
HHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCCEEEECCCCCCH
LALIDHRGHARFDLMLTDIGMPGMDGYGLIRTVRENLGLTATALPAVAVTALAREDDRKR
HHEEECCCCCEEEEEEEECCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCHHHHH
ALESGFQEHLAKPYSVAQLVTAVRAARQAVE
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]