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The map label for this gene is gph [C]

Identifier: 21244346

GI number: 21244346

Start: 4295625

End: 4296320

Strand: Reverse

Name: gph [C]

Synonym: XAC3621

Alternate gene names: 21244346

Gene position: 4296320-4295625 (Counterclockwise)

Preceding gene: 21244347

Following gene: 21244345

Centisome position: 83.01

GC content: 63.94

Gene sequence:

>696_bases
TTGCACTGCGTACACTGCGCCTCTCCCCCACACGAGGCCGTCCGAATGTTTCCGTATTCGCTGGTGATCTTCGATCTGGA
TGGCACGCTGGTGGACAGCGCACCCAATATTGCCGAGGCTCTCAACGGCACCTTGCAGGAGCTGGGGCTGCAGCAGTTCA
GCGAAGAAACGATCCGCGGCTGGATCGGCGAAGGTGTGCATGTCCTGCTTGCCATCGCACTGCGCGAAGCCGGCAGCACC
TGCGATGCCGATGCGGCGATGCCGGTGATGATGCGCCATTACGAGGCGAGCCTGCTGCACGACCCGCAGTTGTATCCCGG
CGTTGCCGAGGCGCTGACGGGCTTGCGCGATGCGGGCGTCACGCTGGCCTTGTGCACCAACAAACCTGCGCGTTTTATCG
CGCCGTTGCTGGAGCATCTGGGCATCGCCGCGCACTTCAGCCGTGTGCTCGGTGGCGATTCGTTGCCGCAGCGCAAGCCC
GACCCGGCGCCGCTGCTGCAGCTTGCCAACCATTTTCAGCGTCGCCCGCAACAGTGTTTGATGGTCGGCGATTCGGCCAC
CGATGCCGCCGCTGCGAACGCCGCGAACATGCCGTTGGCAATGGTGCGTTACGGCTACCTGCGTCGCTTCGATGTGCAGA
CCGCCGGTGCCGTGGCCATCATCGACGACATGCGCGAGCTGCTTGCGTTGAGGTAA

Upstream 100 bases:

>100_bases
TGAGCGGTCCGTGCCGCATTGCGTGTCGCATGCGGCGATGGCTGCATCTGACGCAGGCGGCGAGCAATCCCCAGCGCTTC
GCAGTGACGCGCGCTGAATC

Downstream 100 bases:

>100_bases
GGCGCGCTACGCGATTGGCGTGTGTTGCAGACACCGCCTTTATCAAGGCGGTGTCTGCAACACGGCTCTGCGTCACGGCG
TTCGGCGCGTTTGATTGACA

Product: phosphoglycolate phosphatase

Products: NA

Alternate protein names: PGP; PGPase [H]

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MHCVHCASPPHEAVRMFPYSLVIFDLDGTLVDSAPNIAEALNGTLQELGLQQFSEETIRGWIGEGVHVLLAIALREAGST
CDADAAMPVMMRHYEASLLHDPQLYPGVAEALTGLRDAGVTLALCTNKPARFIAPLLEHLGIAAHFSRVLGGDSLPQRKP
DPAPLLQLANHFQRRPQQCLMVGDSATDAAAANAANMPLAMVRYGYLRRFDVQTAGAVAIIDDMRELLALR

Sequences:

>Translated_231_residues
MHCVHCASPPHEAVRMFPYSLVIFDLDGTLVDSAPNIAEALNGTLQELGLQQFSEETIRGWIGEGVHVLLAIALREAGST
CDADAAMPVMMRHYEASLLHDPQLYPGVAEALTGLRDAGVTLALCTNKPARFIAPLLEHLGIAAHFSRVLGGDSLPQRKP
DPAPLLQLANHFQRRPQQCLMVGDSATDAAAANAANMPLAMVRYGYLRRFDVQTAGAVAIIDDMRELLALR
>Mature_231_residues
MHCVHCASPPHEAVRMFPYSLVIFDLDGTLVDSAPNIAEALNGTLQELGLQQFSEETIRGWIGEGVHVLLAIALREAGST
CDADAAMPVMMRHYEASLLHDPQLYPGVAEALTGLRDAGVTLALCTNKPARFIAPLLEHLGIAAHFSRVLGGDSLPQRKP
DPAPLLQLANHFQRRPQQCLMVGDSATDAAAANAANMPLAMVRYGYLRRFDVQTAGAVAIIDDMRELLALR

Specific function: Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stres

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Escherichia coli, GI1789787, Length=205, Percent_Identity=41.4634146341463, Blast_Score=131, Evalue=4e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR006346
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.18 [H]

Molecular weight: Translated: 24972; Mature: 24972

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHCVHCASPPHEAVRMFPYSLVIFDLDGTLVDSAPNIAEALNGTLQELGLQQFSEETIRG
CCCCCCCCCHHHHHHHCCEEEEEEECCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
WIGEGVHVLLAIALREAGSTCDADAAMPVMMRHYEASLLHDPQLYPGVAEALTGLRDAGV
HHCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCC
TLALCTNKPARFIAPLLEHLGIAAHFSRVLGGDSLPQRKPDPAPLLQLANHFQRRPQQCL
EEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCHHHE
MVGDSATDAAAANAANMPLAMVRYGYLRRFDVQTAGAVAIIDDMRELLALR
EECCCCCHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MHCVHCASPPHEAVRMFPYSLVIFDLDGTLVDSAPNIAEALNGTLQELGLQQFSEETIRG
CCCCCCCCCHHHHHHHCCEEEEEEECCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
WIGEGVHVLLAIALREAGSTCDADAAMPVMMRHYEASLLHDPQLYPGVAEALTGLRDAGV
HHCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCC
TLALCTNKPARFIAPLLEHLGIAAHFSRVLGGDSLPQRKPDPAPLLQLANHFQRRPQQCL
EEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCHHHE
MVGDSATDAAAANAANMPLAMVRYGYLRRFDVQTAGAVAIIDDMRELLALR
EECCCCCHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA