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The map label for this gene is etf-QO [C]

Identifier: 21244300

GI number: 21244300

Start: 4238905

End: 4240554

Strand: Direct

Name: etf-QO [C]

Synonym: XAC3575

Alternate gene names: 21244300

Gene position: 4238905-4240554 (Clockwise)

Preceding gene: 21244298

Following gene: 77748730

Centisome position: 81.9

GC content: 64.42

Gene sequence:

>1650_bases
ATGTCGGAAGCGGGAGTGGGCGCACACGCGTCAGAGGCGGTCGAGCGTGACGTCATGGAATACGACGTCGTCACCGTCGG
TGCCGGTCCGGCCGGGCTGTCGTTCGCGATCCGGCTCAAGCAGCTCGATCCGAACATCAGCGTCTGCGTGATCGAAAAAT
CCAGCACCATCGGCGCGCATATCCTGTCCGGTGCGGTGATCGAGCCCGGCCCGCTGGATGCACTGCTGCCAGGCTGGCGC
GACAATCCGCCGCCGATCTGCGTGGCGGCCACCGACGACGAATTCTGGTTTCTCGGCAAGGACAGCGCGCGCAAGTTCCC
GGTGGTGCCACCGGGCATGCGCAACCATGGCAACTTCATCGTCAGCCTGGGCGCGATGTGCGCCTGGCTGGCGCCGCAGG
CCGAAGCGCTGGGCGTGGAGATCTACCCCGGGTTCGCCGCCGCCGAGACGCTACACGACGACAGCGGCCAGGTGGTGGGC
GTGCGCATTGGCGACATGGGCATTGCAAAAGACGGCTCGCACAAGTCCGGCTACACCGCCGGCATCGACATCCGCGCCAA
GGTGACCGTGCTTGCCGAAGGCGCGCGTGGTCACCTGACCAAGCGATTGTTGAAGCGCTTCGACCTCACCGCCGACAGCG
ACCCGCAAGGCTATTCGATCGGCATCAAGGAGCTGTGGCAGGTCCCGGAAGGCCGCGTCACGCCCGGTAAGATCGTGCAC
ACCATTGGCTGGCCAGCCGACAACCGTACCTACGGCGGCAGCTTTGTGTATCACCTGGACAACAACCAGATTGCGCTCGG
CTATGTGAGCGGGCTGGACTACAGCGACCCGACCTACCAGCCGTGGGAAGCCTTCCAGCAATGGAAGAACCACCCCATGA
TCAAGCCGCTGCTGGAAGGTGGCAGCATCTTGTCTGCCGGTGCCCGCGCACTGGTCAGTGGCGGTTGGCAATCGCTGCCG
AAAGTGGACATGCCCGGCGCCTTGCTCATTGGCGACACCGCCGGCCTGCTCAACGTGCCCAAGATCAAGGGCACCCACCA
GGCGATCCGCAGCGGCATGCTGGCCGCCGAACACCTGGTGCAATCGCAGCTGGCGCCGCAGGGTTTCGATGCCACATTGC
GCGCCTCCGACGTCATGGCCGAGCTGAAGCAAGTCCGCAACATCAAACCCGGTTTCAAGAAAGGCCTGTGGTTCGGCCTG
CTCAACGCGGCCTGGGAAACCGCGCTCAAGGGCGCTTCGCCGTGGACGCTGAAGAACAAACCCGACTGGTCGGCGTTGCA
CAAGCTCGGCGAGTACGAGCGACCCAAGCGCGACTACGTCACCCGCGACCTGGCCCCCCGCGACCGCCTGCAAGCCGTTT
ATTTCGCCGCCACCGAGCACGATGAAGACCAGCCGGTGCATCTGAAGGTGCTGGACACCGATGTATGCGCCACCCGCTGC
GTGACGGAATACGACAACCCCTGCACGCGCTTTTGCCCGGCCAACGTCTACGAAATGGTCGCAGACACCGCCAGCCCCTC
CGGCAAGCGCCTGCAGATCAACGCGGCCAACTGCGTGCACTGCAAGACCTGCGACATCAAGGATCCGTACGAAATCATCA
CCTGGGTCACACCGGAGGGTGGTTCGGGCCCGAACTACCAGAATCTGTGA

Upstream 100 bases:

>100_bases
ACGCAGGCCTGCGCACTGCGGATGAATCGGCACGATTTGCCGCCGTCACATGCAATCCCGGAAAATGCGCGACAGCCATC
GAGCCAACGGGAGCGGAGCA

Downstream 100 bases:

>100_bases
GCGCAACCGGTCGCTCGCTGCAGTCGCGTCTGCGCACATCCGTGTTCGGCCTCTTGCGCGCAGGATTTCGTGCGATACCG
CTGAGCGACGCAACACGCGA

Product: flavoprotein-ubiquinone oxidoreductase

Products: NA

Alternate protein names: ETF-QO; ETF-ubiquinone oxidoreductase; Electron-transferring-flavoprotein dehydrogenase; ETF dehydrogenase [H]

Number of amino acids: Translated: 549; Mature: 548

Protein sequence:

>549_residues
MSEAGVGAHASEAVERDVMEYDVVTVGAGPAGLSFAIRLKQLDPNISVCVIEKSSTIGAHILSGAVIEPGPLDALLPGWR
DNPPPICVAATDDEFWFLGKDSARKFPVVPPGMRNHGNFIVSLGAMCAWLAPQAEALGVEIYPGFAAAETLHDDSGQVVG
VRIGDMGIAKDGSHKSGYTAGIDIRAKVTVLAEGARGHLTKRLLKRFDLTADSDPQGYSIGIKELWQVPEGRVTPGKIVH
TIGWPADNRTYGGSFVYHLDNNQIALGYVSGLDYSDPTYQPWEAFQQWKNHPMIKPLLEGGSILSAGARALVSGGWQSLP
KVDMPGALLIGDTAGLLNVPKIKGTHQAIRSGMLAAEHLVQSQLAPQGFDATLRASDVMAELKQVRNIKPGFKKGLWFGL
LNAAWETALKGASPWTLKNKPDWSALHKLGEYERPKRDYVTRDLAPRDRLQAVYFAATEHDEDQPVHLKVLDTDVCATRC
VTEYDNPCTRFCPANVYEMVADTASPSGKRLQINAANCVHCKTCDIKDPYEIITWVTPEGGSGPNYQNL

Sequences:

>Translated_549_residues
MSEAGVGAHASEAVERDVMEYDVVTVGAGPAGLSFAIRLKQLDPNISVCVIEKSSTIGAHILSGAVIEPGPLDALLPGWR
DNPPPICVAATDDEFWFLGKDSARKFPVVPPGMRNHGNFIVSLGAMCAWLAPQAEALGVEIYPGFAAAETLHDDSGQVVG
VRIGDMGIAKDGSHKSGYTAGIDIRAKVTVLAEGARGHLTKRLLKRFDLTADSDPQGYSIGIKELWQVPEGRVTPGKIVH
TIGWPADNRTYGGSFVYHLDNNQIALGYVSGLDYSDPTYQPWEAFQQWKNHPMIKPLLEGGSILSAGARALVSGGWQSLP
KVDMPGALLIGDTAGLLNVPKIKGTHQAIRSGMLAAEHLVQSQLAPQGFDATLRASDVMAELKQVRNIKPGFKKGLWFGL
LNAAWETALKGASPWTLKNKPDWSALHKLGEYERPKRDYVTRDLAPRDRLQAVYFAATEHDEDQPVHLKVLDTDVCATRC
VTEYDNPCTRFCPANVYEMVADTASPSGKRLQINAANCVHCKTCDIKDPYEIITWVTPEGGSGPNYQNL
>Mature_548_residues
SEAGVGAHASEAVERDVMEYDVVTVGAGPAGLSFAIRLKQLDPNISVCVIEKSSTIGAHILSGAVIEPGPLDALLPGWRD
NPPPICVAATDDEFWFLGKDSARKFPVVPPGMRNHGNFIVSLGAMCAWLAPQAEALGVEIYPGFAAAETLHDDSGQVVGV
RIGDMGIAKDGSHKSGYTAGIDIRAKVTVLAEGARGHLTKRLLKRFDLTADSDPQGYSIGIKELWQVPEGRVTPGKIVHT
IGWPADNRTYGGSFVYHLDNNQIALGYVSGLDYSDPTYQPWEAFQQWKNHPMIKPLLEGGSILSAGARALVSGGWQSLPK
VDMPGALLIGDTAGLLNVPKIKGTHQAIRSGMLAAEHLVQSQLAPQGFDATLRASDVMAELKQVRNIKPGFKKGLWFGLL
NAAWETALKGASPWTLKNKPDWSALHKLGEYERPKRDYVTRDLAPRDRLQAVYFAATEHDEDQPVHLKVLDTDVCATRCV
TEYDNPCTRFCPANVYEMVADTASPSGKRLQINAANCVHCKTCDIKDPYEIITWVTPEGGSGPNYQNL

Specific function: Accepts electrons from ETF and reduces ubiquinone [H]

COG id: COG0644

COG function: function code C; Dehydrogenases (flavoproteins)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI119703746, Length=562, Percent_Identity=47.6868327402135, Blast_Score=496, Evalue=1e-140,
Organism=Escherichia coli, GI1787991, Length=338, Percent_Identity=28.1065088757396, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1786227, Length=331, Percent_Identity=27.190332326284, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI87082155, Length=330, Percent_Identity=26.969696969697, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI25144720, Length=562, Percent_Identity=44.3060498220641, Blast_Score=461, Evalue=1e-130,
Organism=Saccharomyces cerevisiae, GI6324932, Length=570, Percent_Identity=40.8771929824561, Blast_Score=409, Evalue=1e-115,
Organism=Drosophila melanogaster, GI24652256, Length=561, Percent_Identity=44.5632798573975, Blast_Score=467, Evalue=1e-131,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR007859
- InterPro:   IPR003042 [H]

Pfam domain/function: PF05187 ETF_QO [H]

EC number: =1.5.5.1 [H]

Molecular weight: Translated: 59454; Mature: 59323

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEAGVGAHASEAVERDVMEYDVVTVGAGPAGLSFAIRLKQLDPNISVCVIEKSSTIGAH
CCCCCCCCCHHHHHHHHHHHEEEEEECCCCCCCEEEEEEEECCCCEEEEEEECCCCCCHH
ILSGAVIEPGPLDALLPGWRDNPPPICVAATDDEFWFLGKDSARKFPVVPPGMRNHGNFI
HHCCCEECCCCCHHHCCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCEE
VSLGAMCAWLAPQAEALGVEIYPGFAAAETLHDDSGQVVGVRIGDMGIAKDGSHKSGYTA
EEHHHHHHHCCCCCHHCEEEEECCCHHHHHEECCCCCEEEEEECCCCCCCCCCCCCCEEE
GIDIRAKVTVLAEGARGHLTKRLLKRFDLTADSDPQGYSIGIKELWQVPEGRVTPGKIVH
CEEEEEEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCEEECHHHHHCCCCCCCCCCCEEE
TIGWPADNRTYGGSFVYHLDNNQIALGYVSGLDYSDPTYQPWEAFQQWKNHPMIKPLLEG
EECCCCCCCCCCCEEEEEECCCEEEEEEEECCCCCCCCCCHHHHHHHHHCCCCCHHHHCC
GSILSAGARALVSGGWQSLPKVDMPGALLIGDTAGLLNVPKIKGTHQAIRSGMLAAEHLV
CCCHHHHHHHHHCCCHHCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHH
QSQLAPQGFDATLRASDVMAELKQVRNIKPGFKKGLWFGLLNAAWETALKGASPWTLKNK
HHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
PDWSALHKLGEYERPKRDYVTRDLAPRDRLQAVYFAATEHDEDQPVHLKVLDTDVCATRC
CCHHHHHHHHCCCCCCHHHHHCCCCCHHHHEEEEEEECCCCCCCCEEEEEECCHHHHHHH
VTEYDNPCTRFCPANVYEMVADTASPSGKRLQINAANCVHCKTCDIKDPYEIITWVTPEG
HHHCCCCHHHCCCCHHHHHHHHCCCCCCCEEEEECCCEEEEEECCCCCCCEEEEEECCCC
GSGPNYQNL
CCCCCCCCC
>Mature Secondary Structure 
SEAGVGAHASEAVERDVMEYDVVTVGAGPAGLSFAIRLKQLDPNISVCVIEKSSTIGAH
CCCCCCCCHHHHHHHHHHHEEEEEECCCCCCCEEEEEEEECCCCEEEEEEECCCCCCHH
ILSGAVIEPGPLDALLPGWRDNPPPICVAATDDEFWFLGKDSARKFPVVPPGMRNHGNFI
HHCCCEECCCCCHHHCCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCEE
VSLGAMCAWLAPQAEALGVEIYPGFAAAETLHDDSGQVVGVRIGDMGIAKDGSHKSGYTA
EEHHHHHHHCCCCCHHCEEEEECCCHHHHHEECCCCCEEEEEECCCCCCCCCCCCCCEEE
GIDIRAKVTVLAEGARGHLTKRLLKRFDLTADSDPQGYSIGIKELWQVPEGRVTPGKIVH
CEEEEEEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCEEECHHHHHCCCCCCCCCCCEEE
TIGWPADNRTYGGSFVYHLDNNQIALGYVSGLDYSDPTYQPWEAFQQWKNHPMIKPLLEG
EECCCCCCCCCCCEEEEEECCCEEEEEEEECCCCCCCCCCHHHHHHHHHCCCCCHHHHCC
GSILSAGARALVSGGWQSLPKVDMPGALLIGDTAGLLNVPKIKGTHQAIRSGMLAAEHLV
CCCHHHHHHHHHCCCHHCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHH
QSQLAPQGFDATLRASDVMAELKQVRNIKPGFKKGLWFGLLNAAWETALKGASPWTLKNK
HHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
PDWSALHKLGEYERPKRDYVTRDLAPRDRLQAVYFAATEHDEDQPVHLKVLDTDVCATRC
CCHHHHHHHHCCCCCCHHHHHCCCCCHHHHEEEEEEECCCCCCCCEEEEEECCHHHHHHH
VTEYDNPCTRFCPANVYEMVADTASPSGKRLQINAANCVHCKTCDIKDPYEIITWVTPEG
HHHCCCCHHHCCCCHHHHHHHHCCCCCCCEEEEECCCEEEEEECCCCCCCEEEEEECCCC
GSGPNYQNL
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]