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The map label for this gene is sucC [H]

Identifier: 21243962

GI number: 21243962

Start: 3811377

End: 3812546

Strand: Reverse

Name: sucC [H]

Synonym: XAC3236

Alternate gene names: 21243962

Gene position: 3812546-3811377 (Counterclockwise)

Preceding gene: 21243965

Following gene: 21243961

Centisome position: 73.66

GC content: 61.88

Gene sequence:

>1170_bases
ATGAATTTCCACGAATACCAGTCAAAACAGCTGCTTGCCGAGTACGGCATCCCCGTTCCGGCCGGCAAGGTCGCGGCGAC
CCCGGACGAAGCGGTTGAAGTCGCCAATTCCCTGGGCAATGGCCCCTGGATGGTGAAAGCGCAGATCCACGCGGGCGGCC
GCGGTAAGGCTGGCGGCGTCAAGTTCTGCAAGACCACCGACGATGTGAAGGCCGCAGCCGCCAAGATGCTCGGCACCAAG
ATGTCCACCTACCAGACCGCCGGCGTCGAGCTGCCGATCAACCTGGTGCTGGTCACCACCGCCGGTGAGATCGTCAAGGA
GCTGTACCTGTCGATCCTGGTCGACCGCGGTACCAAGACCATCACCTACATCGCATCGAGCGAGGGTGGCGTGGAGATCG
AGCAGGTGGCGGCCGAAACCCCGGAGCTGATCCACGCGCTCAATGTCGATTTCGTCGAAGGCGTGCAGGGCTACCACGGC
CGCGATTTCGGCTTCAAGCTCGGCCTGAACGCCAAGCAGGCCGGACAGTTCGCCAGCATCATGGTGAACCTGTACAAGCT
GTTCAACGAAAAGGACCTGGCGCTGGTTGAAATCAACCCGCTGGCGATCCTGGACGACGGCAACCTGTACGCGCTGGACG
GCAAGTTCGACAGCGACGACAACGCCGCGTTCCGTCAGAAGCAGCTGGTCGCCATGCGCGACAAGACGCAGGAAGACGAA
ACCGAAGTGACCGCTTCGGAGCTGGACATCAACTACGTCACCATGGACGGCAACATCGGGTGCATGGTCAACGGCGCAGG
CCTGGCCATGGCCACCATGGACGTCATCAAGCTCAATGGCGGCGAGCCGGCGAACTTCCTGGACGTGGGCGGCGGCGCGA
ACAAGCAGCGCGTCATCGAAGCGTTCAAGCTGATCCTGTCCTCGGACAAGGTCGAAGGCATCTTCGTCAACATCTTCGGC
GGCATCGTCCGCTGCGACATGATCGCCGAAGGCATCATCGCCGCAGTCAAGGAAGTGGGCGTCAAGGTTCCGGTCGTGGT
GCGCCTGGAAGGCACCAACGTGGAAGAAGGCAAGCAGCTGCTGCGCGACAGCGGCATGGCCATCATCCCGGCCGACAACA
TCAACGACGGCGCCAAGAAAGTCGTTGAAGCTGTCAAGAACGCCGCCTGA

Upstream 100 bases:

>100_bases
CGTGGTCGGCCACAATAGGCGGCCCGTTCGCGTCCCATGACGTGCCGCCCCGGCGGTCTGCGTTGCACGCAGCGGTCGTT
TCCTTTTCCCACGGTGACGC

Downstream 100 bases:

>100_bases
TCCACGCCACCGAAGGAATTATCCATGTCCGTTTTGATTAACAAGAACACCAAGGTGATCGTGCAGGGCTTTACCGGCCA
GCAGGGCACCTTCCACGCCA

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MNFHEYQSKQLLAEYGIPVPAGKVAATPDEAVEVANSLGNGPWMVKAQIHAGGRGKAGGVKFCKTTDDVKAAAAKMLGTK
MSTYQTAGVELPINLVLVTTAGEIVKELYLSILVDRGTKTITYIASSEGGVEIEQVAAETPELIHALNVDFVEGVQGYHG
RDFGFKLGLNAKQAGQFASIMVNLYKLFNEKDLALVEINPLAILDDGNLYALDGKFDSDDNAAFRQKQLVAMRDKTQEDE
TEVTASELDINYVTMDGNIGCMVNGAGLAMATMDVIKLNGGEPANFLDVGGGANKQRVIEAFKLILSSDKVEGIFVNIFG
GIVRCDMIAEGIIAAVKEVGVKVPVVVRLEGTNVEEGKQLLRDSGMAIIPADNINDGAKKVVEAVKNAA

Sequences:

>Translated_389_residues
MNFHEYQSKQLLAEYGIPVPAGKVAATPDEAVEVANSLGNGPWMVKAQIHAGGRGKAGGVKFCKTTDDVKAAAAKMLGTK
MSTYQTAGVELPINLVLVTTAGEIVKELYLSILVDRGTKTITYIASSEGGVEIEQVAAETPELIHALNVDFVEGVQGYHG
RDFGFKLGLNAKQAGQFASIMVNLYKLFNEKDLALVEINPLAILDDGNLYALDGKFDSDDNAAFRQKQLVAMRDKTQEDE
TEVTASELDINYVTMDGNIGCMVNGAGLAMATMDVIKLNGGEPANFLDVGGGANKQRVIEAFKLILSSDKVEGIFVNIFG
GIVRCDMIAEGIIAAVKEVGVKVPVVVRLEGTNVEEGKQLLRDSGMAIIPADNINDGAKKVVEAVKNAA
>Mature_389_residues
MNFHEYQSKQLLAEYGIPVPAGKVAATPDEAVEVANSLGNGPWMVKAQIHAGGRGKAGGVKFCKTTDDVKAAAAKMLGTK
MSTYQTAGVELPINLVLVTTAGEIVKELYLSILVDRGTKTITYIASSEGGVEIEQVAAETPELIHALNVDFVEGVQGYHG
RDFGFKLGLNAKQAGQFASIMVNLYKLFNEKDLALVEINPLAILDDGNLYALDGKFDSDDNAAFRQKQLVAMRDKTQEDE
TEVTASELDINYVTMDGNIGCMVNGAGLAMATMDVIKLNGGEPANFLDVGGGANKQRVIEAFKLILSSDKVEGIFVNIFG
GIVRCDMIAEGIIAAVKEVGVKVPVVVRLEGTNVEEGKQLLRDSGMAIIPADNINDGAKKVVEAVKNAA

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=390, Percent_Identity=46.6666666666667, Blast_Score=348, Evalue=5e-96,
Organism=Homo sapiens, GI157779135, Length=383, Percent_Identity=44.6475195822454, Blast_Score=317, Evalue=1e-86,
Organism=Homo sapiens, GI294862256, Length=363, Percent_Identity=44.9035812672176, Blast_Score=299, Evalue=3e-81,
Organism=Escherichia coli, GI1786948, Length=386, Percent_Identity=58.2901554404145, Blast_Score=447, Evalue=1e-127,
Organism=Caenorhabditis elegans, GI17567829, Length=389, Percent_Identity=46.0154241645244, Blast_Score=331, Evalue=3e-91,
Organism=Caenorhabditis elegans, GI17539378, Length=394, Percent_Identity=41.8781725888325, Blast_Score=304, Evalue=5e-83,
Organism=Saccharomyces cerevisiae, GI6321683, Length=397, Percent_Identity=45.5919395465995, Blast_Score=346, Evalue=4e-96,
Organism=Drosophila melanogaster, GI161078106, Length=385, Percent_Identity=45.1948051948052, Blast_Score=313, Evalue=1e-85,
Organism=Drosophila melanogaster, GI24645208, Length=385, Percent_Identity=45.1948051948052, Blast_Score=313, Evalue=1e-85,
Organism=Drosophila melanogaster, GI281361397, Length=388, Percent_Identity=45.360824742268, Blast_Score=313, Evalue=1e-85,
Organism=Drosophila melanogaster, GI281361395, Length=388, Percent_Identity=45.360824742268, Blast_Score=313, Evalue=1e-85,
Organism=Drosophila melanogaster, GI21356231, Length=394, Percent_Identity=44.1624365482233, Blast_Score=310, Evalue=8e-85,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 41398; Mature: 41398

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS50975 ATP_GRASP ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFHEYQSKQLLAEYGIPVPAGKVAATPDEAVEVANSLGNGPWMVKAQIHAGGRGKAGGV
CCCHHHHHHHHHHHCCCCCCCCCEECCCHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCE
KFCKTTDDVKAAAAKMLGTKMSTYQTAGVELPINLVLVTTAGEIVKELYLSILVDRGTKT
EEECCCHHHHHHHHHHHHCHHHHEEECCEEEEEEEEEEECHHHHHHHHHHHHHHCCCCEE
ITYIASSEGGVEIEQVAAETPELIHALNVDFVEGVQGYHGRDFGFKLGLNAKQAGQFASI
EEEEECCCCCEEHHHHHCCCHHHHHHHCCHHHHHCCCCCCCCCCEEECCCHHHHHHHHHH
MVNLYKLFNEKDLALVEINPLAILDDGNLYALDGKFDSDDNAAFRQKQLVAMRDKTQEDE
HHHHHHHHCCCCEEEEEECCEEEEECCCEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCH
TEVTASELDINYVTMDGNIGCMVNGAGLAMATMDVIKLNGGEPANFLDVGGGANKQRVIE
HHEEHHHEEEEEEEECCCEEEEEECCCEEEEEEEEEEECCCCCCCEEECCCCCCHHHHHH
AFKLILSSDKVEGIFVNIFGGIVRCDMIAEGIIAAVKEVGVKVPVVVRLEGTNVEEGKQL
HHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHH
LRDSGMAIIPADNINDGAKKVVEAVKNAA
HHHCCCEEEECCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MNFHEYQSKQLLAEYGIPVPAGKVAATPDEAVEVANSLGNGPWMVKAQIHAGGRGKAGGV
CCCHHHHHHHHHHHCCCCCCCCCEECCCHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCE
KFCKTTDDVKAAAAKMLGTKMSTYQTAGVELPINLVLVTTAGEIVKELYLSILVDRGTKT
EEECCCHHHHHHHHHHHHCHHHHEEECCEEEEEEEEEEECHHHHHHHHHHHHHHCCCCEE
ITYIASSEGGVEIEQVAAETPELIHALNVDFVEGVQGYHGRDFGFKLGLNAKQAGQFASI
EEEEECCCCCEEHHHHHCCCHHHHHHHCCHHHHHCCCCCCCCCCEEECCCHHHHHHHHHH
MVNLYKLFNEKDLALVEINPLAILDDGNLYALDGKFDSDDNAAFRQKQLVAMRDKTQEDE
HHHHHHHHCCCCEEEEEECCEEEEECCCEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCH
TEVTASELDINYVTMDGNIGCMVNGAGLAMATMDVIKLNGGEPANFLDVGGGANKQRVIE
HHEEHHHEEEEEEEECCCEEEEEECCCEEEEEEEEEEECCCCCCCEEECCCCCCHHHHHH
AFKLILSSDKVEGIFVNIFGGIVRCDMIAEGIIAAVKEVGVKVPVVVRLEGTNVEEGKQL
HHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHH
LRDSGMAIIPADNINDGAKKVVEAVKNAA
HHHCCCEEEECCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA