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The map label for this gene is lysA [H]

Identifier: 21243907

GI number: 21243907

Start: 3743615

End: 3744811

Strand: Direct

Name: lysA [H]

Synonym: XAC3181

Alternate gene names: 21243907

Gene position: 3743615-3744811 (Clockwise)

Preceding gene: 21243906

Following gene: 21243908

Centisome position: 72.33

GC content: 66.08

Gene sequence:

>1197_bases
GTGAGCCTGCAGATCGATACCGCGGCAATGCTTGCTGCCTTGCCGCGGGTGCGCGAACGCTGCGATGGTCCGATCTGCGC
GTATGTCTACGATCTGGCCGCATTGGACACGCACGCGGCCTGGATGCGTGCGCAGTTGCCGGCGCAGTGCGAACTGTTCT
ATGCGGCCAAGGCCAATGCAGAGCCACCGATCCTGCGCACGCTGGCACCCCATGTGGACGGCTTCGAGGCCGCCTCCGGT
GGCGAGCTGGCCTGGCTGCATGCGCAGCAACCACAGGCGCCCTTGCTGTTTGGCGGACCGGGAAAACTCGACACCGAGCT
CGCCCAGGCAGCCGCCCTGCCCGACTGCACCGTGCATGTGGAAAGCCTGAGCGAACTCGAACGGCTGGCGGAGGTCGCTT
CGCACGCCGGCCGCTGCGTGCCGGTGTTTCTGCGCATGAATATCGCCGTGCCCGGCGCGCAAAGCACGCGCTTGATGATG
GGCGGGCAACCCTCGCCGTTCGGTCTGGATCCGTGCGATCTGCATGCAGCGATGCAGCGACTGCAGGCGAGCCCATCGCT
GCGCCTGGCAGGCTTTCATTTCCATCTGATGTCGCATCAACGCGACGCCACCGCGCAGCTGCATCTGGTCGCCGCCTACC
TGCGCACCGTGCAGCAATGGCGGCAGGCCTATGCGCTTGGCCCACTGCGGGTAAACGCCGGTGGCGGCTTCGGTGTGGAT
TATCTGGCACCGGAAGCGTCGTTCGACTGGGCTGGCTTCTGCGCCGGGCTGCCTGCCTTGCTGCGCGAACACGCTACGGA
CCTGCGCCTGCGGCTGGAGCCGGGCCGTTACGTCAGCGCCAGCTGCGGCTGGTACCTGATGGAGGTGCTCGATCTCAAAC
GCAGCCACGGCGCCTGGTTTGCGATCGCCCGCGGTGGCACGCATCACTTTCGTACGCCGGCCGCGCAAGGCCACGATCAT
CCGTTCCGTGTATTGCGCGGTGAGCGTGCTCCAGTGTTGCGCGATACCCCGGTGACCCTGGTCGGCCAGTTATGCACGCC
CAAGGATGTGCTGGCACGCGACCAGCATGTCGCCGCGCTGGCGCCTGGCGATTGCCTGGCCTTCCCGCTAGCGGGCGCCT
ATGCGTGGAATATTTCGCACCAGCGCTTTCTGATGCATCCGGCACCGCAGATGGTGTTTCTAACGGAGGGGCATTGA

Upstream 100 bases:

>100_bases
ATCTGGGTACCCGTCTATGGCAGCGTGCCGATCGCCAATCCGACTACACCGCGCTGCCCAATCCCATCCCTCGCACCGCG
GCGCAGCGGCAGGTGGCGGC

Downstream 100 bases:

>100_bases
CTTACCGATTGCGGACGAACAACGCTTGGGCCTACGTCAGCAGGCTCACAGGCAGATGTGCTGTTGCCGCAATTTCCTGC
GTTGACTCGAAGTAGCTGTG

Product: diaminopimelate decarboxylase

Products: NA

Alternate protein names: DAP decarboxylase [H]

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MSLQIDTAAMLAALPRVRERCDGPICAYVYDLAALDTHAAWMRAQLPAQCELFYAAKANAEPPILRTLAPHVDGFEAASG
GELAWLHAQQPQAPLLFGGPGKLDTELAQAAALPDCTVHVESLSELERLAEVASHAGRCVPVFLRMNIAVPGAQSTRLMM
GGQPSPFGLDPCDLHAAMQRLQASPSLRLAGFHFHLMSHQRDATAQLHLVAAYLRTVQQWRQAYALGPLRVNAGGGFGVD
YLAPEASFDWAGFCAGLPALLREHATDLRLRLEPGRYVSASCGWYLMEVLDLKRSHGAWFAIARGGTHHFRTPAAQGHDH
PFRVLRGERAPVLRDTPVTLVGQLCTPKDVLARDQHVAALAPGDCLAFPLAGAYAWNISHQRFLMHPAPQMVFLTEGH

Sequences:

>Translated_398_residues
MSLQIDTAAMLAALPRVRERCDGPICAYVYDLAALDTHAAWMRAQLPAQCELFYAAKANAEPPILRTLAPHVDGFEAASG
GELAWLHAQQPQAPLLFGGPGKLDTELAQAAALPDCTVHVESLSELERLAEVASHAGRCVPVFLRMNIAVPGAQSTRLMM
GGQPSPFGLDPCDLHAAMQRLQASPSLRLAGFHFHLMSHQRDATAQLHLVAAYLRTVQQWRQAYALGPLRVNAGGGFGVD
YLAPEASFDWAGFCAGLPALLREHATDLRLRLEPGRYVSASCGWYLMEVLDLKRSHGAWFAIARGGTHHFRTPAAQGHDH
PFRVLRGERAPVLRDTPVTLVGQLCTPKDVLARDQHVAALAPGDCLAFPLAGAYAWNISHQRFLMHPAPQMVFLTEGH
>Mature_397_residues
SLQIDTAAMLAALPRVRERCDGPICAYVYDLAALDTHAAWMRAQLPAQCELFYAAKANAEPPILRTLAPHVDGFEAASGG
ELAWLHAQQPQAPLLFGGPGKLDTELAQAAALPDCTVHVESLSELERLAEVASHAGRCVPVFLRMNIAVPGAQSTRLMMG
GQPSPFGLDPCDLHAAMQRLQASPSLRLAGFHFHLMSHQRDATAQLHLVAAYLRTVQQWRQAYALGPLRVNAGGGFGVDY
LAPEASFDWAGFCAGLPALLREHATDLRLRLEPGRYVSASCGWYLMEVLDLKRSHGAWFAIARGGTHHFRTPAAQGHDHP
FRVLRGERAPVLRDTPVTLVGQLCTPKDVLARDQHVAALAPGDCLAFPLAGAYAWNISHQRFLMHPAPQMVFLTEGH

Specific function: Lysine biosynthesis; last step. [C]

COG id: COG0019

COG function: function code E; Diaminopimelate decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-II family [H]

Homologues:

Organism=Escherichia coli, GI1789203, Length=392, Percent_Identity=24.4897959183673, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009006
- InterPro:   IPR002986
- InterPro:   IPR022643
- InterPro:   IPR022644
- InterPro:   IPR022653
- InterPro:   IPR000183 [H]

Pfam domain/function: PF02784 Orn_Arg_deC_N; PF00278 Orn_DAP_Arg_deC [H]

EC number: =4.1.1.20 [H]

Molecular weight: Translated: 43278; Mature: 43147

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: PS00879 ODR_DC_2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLQIDTAAMLAALPRVRERCDGPICAYVYDLAALDTHAAWMRAQLPAQCELFYAAKANA
CCEECHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCC
EPPILRTLAPHVDGFEAASGGELAWLHAQQPQAPLLFGGPGKLDTELAQAAALPDCTVHV
CCCHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCEEECCCCCCHHHHHHHHCCCCCEEEH
ESLSELERLAEVASHAGRCVPVFLRMNIAVPGAQSTRLMMGGQPSPFGLDPCDLHAAMQR
HHHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCCCCEEEECCCCCCCCCCHHHHHHHHHH
LQASPSLRLAGFHFHLMSHQRDATAQLHLVAAYLRTVQQWRQAYALGPLRVNAGGGFGVD
HHCCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCH
YLAPEASFDWAGFCAGLPALLREHATDLRLRLEPGRYVSASCGWYLMEVLDLKRSHGAWF
HCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCEEECCCHHHHHHHHHHHCCCCCEE
AIARGGTHHFRTPAAQGHDHPFRVLRGERAPVLRDTPVTLVGQLCTPKDVLARDQHVAAL
EEECCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCHHHHHCCCCCHHHHHCCCCEEEE
APGDCLAFPLAGAYAWNISHQRFLMHPAPQMVFLTEGH
CCCCEEEECCCCEEEECCCCCEEEECCCCCEEEEECCC
>Mature Secondary Structure 
SLQIDTAAMLAALPRVRERCDGPICAYVYDLAALDTHAAWMRAQLPAQCELFYAAKANA
CEECHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCC
EPPILRTLAPHVDGFEAASGGELAWLHAQQPQAPLLFGGPGKLDTELAQAAALPDCTVHV
CCCHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCEEECCCCCCHHHHHHHHCCCCCEEEH
ESLSELERLAEVASHAGRCVPVFLRMNIAVPGAQSTRLMMGGQPSPFGLDPCDLHAAMQR
HHHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCCCCEEEECCCCCCCCCCHHHHHHHHHH
LQASPSLRLAGFHFHLMSHQRDATAQLHLVAAYLRTVQQWRQAYALGPLRVNAGGGFGVD
HHCCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCH
YLAPEASFDWAGFCAGLPALLREHATDLRLRLEPGRYVSASCGWYLMEVLDLKRSHGAWF
HCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCEEECCCHHHHHHHHHHHCCCCCEE
AIARGGTHHFRTPAAQGHDHPFRVLRGERAPVLRDTPVTLVGQLCTPKDVLARDQHVAAL
EEECCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCHHHHHCCCCCHHHHHCCCCEEEE
APGDCLAFPLAGAYAWNISHQRFLMHPAPQMVFLTEGH
CCCCEEEECCCCEEEECCCCCEEEECCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]