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The map label for this gene is ruvA

Identifier: 21243875

GI number: 21243875

Start: 3700184

End: 3700768

Strand: Reverse

Name: ruvA

Synonym: XAC3149

Alternate gene names: 21243875

Gene position: 3700768-3700184 (Counterclockwise)

Preceding gene: 21243876

Following gene: 21243874

Centisome position: 71.5

GC content: 67.35

Gene sequence:

>585_bases
GTGATCGGCCGTCTGCGCGGGATCCTGGCCTACAAGCAGCCGCCGTGGCTGGTGATCGACGTAGGTGGGGTGGGGTATGA
GCTAGAGGCGCCGATGAGCACCTTCTACGACCTGCCCGATGTCGGTCGCGACGTGATCCTGTTTACCCATTACGCGCAAA
AGGAAGACAGCGTGTCGCTGTATGGCTTCCTGCGCGAAGGCGAGCGGCGGCTGTTCCGCGACGTGCAGAAGGTCACCGGC
ATCGGCGCCAAGATCGCGCTGGCGGTGTTGTCCGGGGTCAGCGTGGACGAGTTCGCCCGCCTGATCACCAGCGGCGACAT
CACCGCGCTGACGCGCATTCCCGGCATCGGCAAGAAGACCGCCGAGCGCATGGTGGTGGAACTGCGCGACCGCGCCGCCG
ATTTCAGCAGCGGCGCACCGATTACCGGCCAGTTGGGGCCCGACGCCGTTTCCGAAGCCACCGTGGCCTTGCAACAGCTG
GGCTACAAGCCGGCCGAGGCCGCCCGCATGGCGCGCGACGCCGGTGCAGAAGGCGACGAGGTCGCGACGGTCATTCGCAA
GGCGCTGCAGGCCGCGCTGCGCTAA

Upstream 100 bases:

>100_bases
CGGGAATCGGGAATCCCAAACGCAGGGTCCACGACAGCGCGCGCTGTTGCGATTGGCCATTCCCGATTCCCCATTCCCGG
CACCGCCAAGGCGGTGCCCA

Downstream 100 bases:

>100_bases
GCGCGGCCACGAACCATCGCCTGGCCCGCAAAGCGGGCGCGGCCGGCACTCGGCATCGACAGGGGCGGCCCGTACACTGC
GCATCCTTGCCCGCGGCCAG

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MIGRLRGILAYKQPPWLVIDVGGVGYELEAPMSTFYDLPDVGRDVILFTHYAQKEDSVSLYGFLREGERRLFRDVQKVTG
IGAKIALAVLSGVSVDEFARLITSGDITALTRIPGIGKKTAERMVVELRDRAADFSSGAPITGQLGPDAVSEATVALQQL
GYKPAEAARMARDAGAEGDEVATVIRKALQAALR

Sequences:

>Translated_194_residues
MIGRLRGILAYKQPPWLVIDVGGVGYELEAPMSTFYDLPDVGRDVILFTHYAQKEDSVSLYGFLREGERRLFRDVQKVTG
IGAKIALAVLSGVSVDEFARLITSGDITALTRIPGIGKKTAERMVVELRDRAADFSSGAPITGQLGPDAVSEATVALQQL
GYKPAEAARMARDAGAEGDEVATVIRKALQAALR
>Mature_194_residues
MIGRLRGILAYKQPPWLVIDVGGVGYELEAPMSTFYDLPDVGRDVILFTHYAQKEDSVSLYGFLREGERRLFRDVQKVTG
IGAKIALAVLSGVSVDEFARLITSGDITALTRIPGIGKKTAERMVVELRDRAADFSSGAPITGQLGPDAVSEATVALQQL
GYKPAEAARMARDAGAEGDEVATVIRKALQAALR

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family

Homologues:

Organism=Escherichia coli, GI1788168, Length=207, Percent_Identity=47.3429951690821, Blast_Score=187, Evalue=3e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVA_XANAC (Q8PHV0)

Other databases:

- EMBL:   AE008923
- RefSeq:   NP_643457.1
- ProteinModelPortal:   Q8PHV0
- SMR:   Q8PHV0
- GeneID:   1157220
- GenomeReviews:   AE008923_GR
- KEGG:   xac:XAC3149
- NMPDR:   fig|190486.1.peg.3101
- HOGENOM:   HBG635309
- OMA:   LFGFAQK
- ProtClustDB:   PRK00116
- BioCyc:   XAXO190486:XAC3149-MONOMER
- HAMAP:   MF_00031
- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00278
- TIGRFAMs:   TIGR00084

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N; SSF50249 Nucleic_acid_OB; SSF47781 RuvA_2_like; SSF46929 RuvA_C-like

EC number: =3.6.4.12

Molecular weight: Translated: 20878; Mature: 20878

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGRLRGILAYKQPPWLVIDVGGVGYELEAPMSTFYDLPDVGRDVILFTHYAQKEDSVSL
CCCCHHHHHEECCCCEEEEECCCCCEECCCCHHHHCCCCCCCCCEEEEEECCCCCCCCHH
YGFLREGERRLFRDVQKVTGIGAKIALAVLSGVSVDEFARLITSGDITALTRIPGIGKKT
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHCCCCCHHH
AERMVVELRDRAADFSSGAPITGQLGPDAVSEATVALQQLGYKPAEAARMARDAGAEGDE
HHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHH
VATVIRKALQAALR
HHHHHHHHHHHHCC
>Mature Secondary Structure
MIGRLRGILAYKQPPWLVIDVGGVGYELEAPMSTFYDLPDVGRDVILFTHYAQKEDSVSL
CCCCHHHHHEECCCCEEEEECCCCCEECCCCHHHHCCCCCCCCCEEEEEECCCCCCCCHH
YGFLREGERRLFRDVQKVTGIGAKIALAVLSGVSVDEFARLITSGDITALTRIPGIGKKT
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHCCCCCHHH
AERMVVELRDRAADFSSGAPITGQLGPDAVSEATVALQQLGYKPAEAARMARDAGAEGDE
HHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHH
VATVIRKALQAALR
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217