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The map label for this gene is ruvB

Identifier: 21243873

GI number: 21243873

Start: 3696770

End: 3697810

Strand: Reverse

Name: ruvB

Synonym: XAC3147

Alternate gene names: 21243873

Gene position: 3697810-3696770 (Counterclockwise)

Preceding gene: 21243874

Following gene: 21243872

Centisome position: 71.45

GC content: 65.99

Gene sequence:

>1041_bases
ATGACTGAGCAGCGCATCATCGCCAGCAGCTCCACCCGCGAAGACGATGCCGCCGATGCGAGCATTCGTCCCAAGCGCCT
GGCCGATTATCTCGGCCAGCAACCGGTGCGCGAGCAGATGGAGATCTACATCCAGGCGGCCAAGGCGCGTGGCGAGGCGA
TGGATCATGTGCTGATCTTCGGCCCGCCGGGGCTCGGCAAGACCACGCTCAGTCACGTCATTGCCAACGAGCTGGGCGTG
AGCCTGCGCGTGACCTCCGGCCCGGTGATCGAAAAGGCCGGCGATCTCGCGGCGTTGTTGACCAACCTGCAGCCGCACGA
TGTGTTGTTCATCGACGAAATCCATCGCCTCTCGCCGGTGGTGGAGGAAGTGCTGTATCCGGCAATGGAAGATTTCCAGA
TCGACATCATGATCGGCGACGGCCCGGCCGCGCGTTCGATCAAGATCGACCTGCCGCCGTTCACCCTGATCGGTGCCACC
ACGCGTGCCGGATTGCTGACCGCACCGCTGCGCGACCGCTTCGGCATCGTGCAGCGGCTGGAGTTCTATTCCCCGCAGGA
ACTGACCCGCATCGTGATCCGCTCGGCGGCGATTCTCGGCATCGACTGCACGGCCGAAGGTGCGGCGGAAATCGCACGCC
GTGCGCGCGGCACCCCGCGTATCGCCAACCGCTTGCTGCGTCGCGTGCGCGACTACGCCCAGGTCAAGGCGGCCGGGCAT
ATCGATCTGCCGGTGGCGCAGGCGGCCATGCAGATGCTCAAGGTCGACCCGGAAGGCTTTGACGAGCTCGACCGCCGCAT
GTTGCGCACCATCGTCGAACACTTCGACGGCGGCCCGGTCGGCGTGGAATCGCTGGCCGCCTCGCTGTCGGAGGAGCGCG
GCACGCTGGAAGATGTGATCGAGCCGTACCTGATCCAGCAGGGCTTTCTGATCCGCACCGCGCGCGGCCGCATGGTCACG
CCCAAGGCCTATCTGCACCTGGGCCTGAAACCGCCGCGCGAGCGCGCCCCGGGCATTGGCGAACCGGGAGACCTGTTTTG
A

Upstream 100 bases:

>100_bases
GCGCGCCGCGAGCTTCGAAGCCTTCTTCGCAGTGCTGCGCCAGGCCGGGCTTGATGTCTAGATGCTGGGCCATCCGCGCG
CGGCATGAGAAGATGGCCGG

Downstream 100 bases:

>100_bases
CGACGCTCTGCTGGTCGCCAACCTGGGCCGTCGCGACCGGAACTCCCTGCCCATGACCATCGAATCCCCATTCCCCAATC
CCCAATCCCTGCCGGTATTC

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 345

Protein sequence:

>346_residues
MTEQRIIASSSTREDDAADASIRPKRLADYLGQQPVREQMEIYIQAAKARGEAMDHVLIFGPPGLGKTTLSHVIANELGV
SLRVTSGPVIEKAGDLAALLTNLQPHDVLFIDEIHRLSPVVEEVLYPAMEDFQIDIMIGDGPAARSIKIDLPPFTLIGAT
TRAGLLTAPLRDRFGIVQRLEFYSPQELTRIVIRSAAILGIDCTAEGAAEIARRARGTPRIANRLLRRVRDYAQVKAAGH
IDLPVAQAAMQMLKVDPEGFDELDRRMLRTIVEHFDGGPVGVESLAASLSEERGTLEDVIEPYLIQQGFLIRTARGRMVT
PKAYLHLGLKPPRERAPGIGEPGDLF

Sequences:

>Translated_346_residues
MTEQRIIASSSTREDDAADASIRPKRLADYLGQQPVREQMEIYIQAAKARGEAMDHVLIFGPPGLGKTTLSHVIANELGV
SLRVTSGPVIEKAGDLAALLTNLQPHDVLFIDEIHRLSPVVEEVLYPAMEDFQIDIMIGDGPAARSIKIDLPPFTLIGAT
TRAGLLTAPLRDRFGIVQRLEFYSPQELTRIVIRSAAILGIDCTAEGAAEIARRARGTPRIANRLLRRVRDYAQVKAAGH
IDLPVAQAAMQMLKVDPEGFDELDRRMLRTIVEHFDGGPVGVESLAASLSEERGTLEDVIEPYLIQQGFLIRTARGRMVT
PKAYLHLGLKPPRERAPGIGEPGDLF
>Mature_345_residues
TEQRIIASSSTREDDAADASIRPKRLADYLGQQPVREQMEIYIQAAKARGEAMDHVLIFGPPGLGKTTLSHVIANELGVS
LRVTSGPVIEKAGDLAALLTNLQPHDVLFIDEIHRLSPVVEEVLYPAMEDFQIDIMIGDGPAARSIKIDLPPFTLIGATT
RAGLLTAPLRDRFGIVQRLEFYSPQELTRIVIRSAAILGIDCTAEGAAEIARRARGTPRIANRLLRRVRDYAQVKAAGHI
DLPVAQAAMQMLKVDPEGFDELDRRMLRTIVEHFDGGPVGVESLAASLSEERGTLEDVIEPYLIQQGFLIRTARGRMVTP
KAYLHLGLKPPRERAPGIGEPGDLF

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family

Homologues:

Organism=Escherichia coli, GI1788167, Length=328, Percent_Identity=68.9024390243902, Blast_Score=469, Evalue=1e-133,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVB_XANAC (Q8PHV2)

Other databases:

- EMBL:   AE008923
- RefSeq:   NP_643455.1
- ProteinModelPortal:   Q8PHV2
- SMR:   Q8PHV2
- GeneID:   1157218
- GenomeReviews:   AE008923_GR
- KEGG:   xac:XAC3147
- NMPDR:   fig|190486.1.peg.3099
- HOGENOM:   HBG339960
- OMA:   EKFDGGP
- ProtClustDB:   PRK00080
- BioCyc:   XAXO190486:XAC3147-MONOMER
- HAMAP:   MF_00016
- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- ProDom:   PD005323
- SMART:   SM00382
- TIGRFAMs:   TIGR00635

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N

EC number: =3.6.4.12

Molecular weight: Translated: 37944; Mature: 37813

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEQRIIASSSTREDDAADASIRPKRLADYLGQQPVREQMEIYIQAAKARGEAMDHVLIF
CCCCCEECCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEEE
GPPGLGKTTLSHVIANELGVSLRVTSGPVIEKAGDLAALLTNLQPHDVLFIDEIHRLSPV
CCCCCCHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHH
VEEVLYPAMEDFQIDIMIGDGPAARSIKIDLPPFTLIGATTRAGLLTAPLRDRFGIVQRL
HHHHHHCCCCCEEEEEEECCCCCCCEEEEECCCEEEECCCHHCCEEECCHHHHHHHHHHH
EFYSPQELTRIVIRSAAILGIDCTAEGAAEIARRARGTPRIANRLLRRVRDYAQVKAAGH
HHCCHHHHHHHHHHHHHHEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCC
IDLPVAQAAMQMLKVDPEGFDELDRRMLRTIVEHFDGGPVGVESLAASLSEERGTLEDVI
CCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHH
EPYLIQQGFLIRTARGRMVTPKAYLHLGLKPPRERAPGIGEPGDLF
HHHHHHCCCEEEECCCCEECCHHHEEECCCCCHHHCCCCCCCCCCC
>Mature Secondary Structure 
TEQRIIASSSTREDDAADASIRPKRLADYLGQQPVREQMEIYIQAAKARGEAMDHVLIF
CCCCEECCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEEE
GPPGLGKTTLSHVIANELGVSLRVTSGPVIEKAGDLAALLTNLQPHDVLFIDEIHRLSPV
CCCCCCHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHH
VEEVLYPAMEDFQIDIMIGDGPAARSIKIDLPPFTLIGATTRAGLLTAPLRDRFGIVQRL
HHHHHHCCCCCEEEEEEECCCCCCCEEEEECCCEEEECCCHHCCEEECCHHHHHHHHHHH
EFYSPQELTRIVIRSAAILGIDCTAEGAAEIARRARGTPRIANRLLRRVRDYAQVKAAGH
HHCCHHHHHHHHHHHHHHEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCC
IDLPVAQAAMQMLKVDPEGFDELDRRMLRTIVEHFDGGPVGVESLAASLSEERGTLEDVI
CCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHH
EPYLIQQGFLIRTARGRMVTPKAYLHLGLKPPRERAPGIGEPGDLF
HHHHHHCCCEEEECCCCEECCHHHEEECCCCCHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217