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The map label for this gene is bga [H]

Identifier: 21243811

GI number: 21243811

Start: 3620253

End: 3622094

Strand: Direct

Name: bga [H]

Synonym: XAC3084

Alternate gene names: 21243811

Gene position: 3620253-3622094 (Clockwise)

Preceding gene: 21243810

Following gene: 21243813

Centisome position: 69.95

GC content: 65.58

Gene sequence:

>1842_bases
ATGCTGCGCACCACCCTTGCACCGCTCGTCCTGGCCCTCGCGTTCGCGCTTCCTATCACCGGCACAGCCGCAGAGACCGA
ACGCTGGCCGAACTTCGGCACGCAGGGCACGCAGTTCGTGCGCGACGGCAAGCCCTATCAACTGCTTTCCGGCGCCATCC
ATTTCCAGCGCATTCCGCGCGCCTACTGGAAAGACCGCCTGCAAAAAGCGCGTGCACTGGGCTTGAACACCGTGGAAACC
TACGTGTTCTGGAATCTGGTGGAACCGCAGCAAGGCCAGTTCGATTTTTCCGGTCACAACGATGTGGCCGCGTTCGTGCG
CGAAGCCGCCGCGCAGGGGTTGAACGTCATCCTGCGGCCCGGCCCTTATGCCTGCGCAGAGTGGGAAGCCGGCGGCTACC
CGGCCTGGTTGTTCGGCAAGGGCAACATCCGCGTCCGCAGCCGCGACCCGCGCTTTCTCGCCGCCAGCCAGGCGTATCTG
GACGCACTGGCCAACCAGGTGCAGCCGCTGCTCAACCACAATGGTGGGCCGATCATCGCCGTGCAGGTGGAGAACGAATA
CGGCTCTTACGCCGACGACCACGCGTACATGGCCGACAACCGCGCCATGTACGTCAAGGCCGGCTTCGACAAGGCCTTGC
TGTTCACCTCCGATGGCGCCGACATGCTCGCCAACGGCACCTTGCCCGACACCCTGGCGGTGGTGAACTTCGCACCCGGC
GAGGCCAAGAGCGCATTCGACAAACTGATCAAGTTCCGCCCCGATCAACCGCGCATGGTCGGCGAATACTGGGCCGGGTG
GTTCGACCATTGGGGCAAGCCGCACGCCGCCACCGATGCCAGGCAACAGGCCGAGGAGTTCGAGTGGATCCTGCGCCAGG
GTCACTCGGCCAATCTCTACATGTTTATCGGCGGCACCAGTTTCGGCTTCATGAATGGCGCCAATTTCCAGAACAATCCC
AGTGACCACTACGCGCCGCAGACCACCAGCTACGACTACGACGCCATCCTCGACGAAGCCGGGCACCCTACGCCCAAGTT
CGCGTTGATGCGCGATGCCATCGCCCGCGTGACCGGCGTGCAACCGCCCGCATTACCGGCGCCGATCGCGACCACCACGC
TGCCAGACACGCCGCTGCGCGAATCGGCCTCGCTCTGGGACAACCTGCCCGCACCGATCGCCATCGACACCCCGCAGCCG
ATGGAGCAGTTCGGCCAGGATTACGGCTACATCCTCTACCGCACCACCGTCACCGGCCCGCGCAAGGGCCCGCTGTATCT
GGGCGATGTGCGCGATGTGGCGCGCGTGTACGTGGATCAACGACCGGTCGGCAGCGTCGAACGGCGTTTGCAGCAGGTGT
CCCTCGATGTAGAGATTCCTGCAGGCCAGCACACCCTGGATGTCCTGGTCGAAAACAGCGGCCGCATCAATTACGGCACG
CGCATGGCCGACGGCCGCGCCGGCCTGGTCGACCCGGTCGTGCTGGACAACCGGCAACTCACCGGCTGGCAGGCCTTCCC
GCTGCCCATGCGCACGCCCGACAGCATCCGCGGCTGGACCCGCAAGGCCGTGCAAGGCCCGGCGTTCCACCGCGGCACCC
TGCGCATCGGCACGCCGACCGACACCTATCTGGACATGCGCGCCTTCGGCAAGGGCTTCGCCTGGGCCAACGGTGTCAAC
CTGGGCCGCCACTGGAATATCGGCCCGCAGACCGCGCTGTATTTCCCCGCGCCGTTCCAGCGCAAGGGTGACAACACGGT
GGTGGTCTTCGATCTGGACGATGTCGCCACCCCCAGCGTGCGCGGCCTGAAGCAGCAGGTGTGGCTCAAGCCGAAGGAGT
GA

Upstream 100 bases:

>100_bases
AAGGTGCCCGGAGGGCGGATGAGGGCCACCATCAACACCGATCCACCCAAAACCTCATCCACCGCCATCACCCGTCATTG
GTTACCGCCGAGAATCGCTC

Downstream 100 bases:

>100_bases
GTCTCACGAGGCGGCGGCGGCCGACGCATGTGCGCGCGCACAGCCGCCATCAGGTCGTGGACGCAGGCGTCGCGGCAGCG
GCCTGTTCGCGGATGCGTGC

Product: beta-galactosidase

Products: NA

Alternate protein names: Lactase [H]

Number of amino acids: Translated: 613; Mature: 613

Protein sequence:

>613_residues
MLRTTLAPLVLALAFALPITGTAAETERWPNFGTQGTQFVRDGKPYQLLSGAIHFQRIPRAYWKDRLQKARALGLNTVET
YVFWNLVEPQQGQFDFSGHNDVAAFVREAAAQGLNVILRPGPYACAEWEAGGYPAWLFGKGNIRVRSRDPRFLAASQAYL
DALANQVQPLLNHNGGPIIAVQVENEYGSYADDHAYMADNRAMYVKAGFDKALLFTSDGADMLANGTLPDTLAVVNFAPG
EAKSAFDKLIKFRPDQPRMVGEYWAGWFDHWGKPHAATDARQQAEEFEWILRQGHSANLYMFIGGTSFGFMNGANFQNNP
SDHYAPQTTSYDYDAILDEAGHPTPKFALMRDAIARVTGVQPPALPAPIATTTLPDTPLRESASLWDNLPAPIAIDTPQP
MEQFGQDYGYILYRTTVTGPRKGPLYLGDVRDVARVYVDQRPVGSVERRLQQVSLDVEIPAGQHTLDVLVENSGRINYGT
RMADGRAGLVDPVVLDNRQLTGWQAFPLPMRTPDSIRGWTRKAVQGPAFHRGTLRIGTPTDTYLDMRAFGKGFAWANGVN
LGRHWNIGPQTALYFPAPFQRKGDNTVVVFDLDDVATPSVRGLKQQVWLKPKE

Sequences:

>Translated_613_residues
MLRTTLAPLVLALAFALPITGTAAETERWPNFGTQGTQFVRDGKPYQLLSGAIHFQRIPRAYWKDRLQKARALGLNTVET
YVFWNLVEPQQGQFDFSGHNDVAAFVREAAAQGLNVILRPGPYACAEWEAGGYPAWLFGKGNIRVRSRDPRFLAASQAYL
DALANQVQPLLNHNGGPIIAVQVENEYGSYADDHAYMADNRAMYVKAGFDKALLFTSDGADMLANGTLPDTLAVVNFAPG
EAKSAFDKLIKFRPDQPRMVGEYWAGWFDHWGKPHAATDARQQAEEFEWILRQGHSANLYMFIGGTSFGFMNGANFQNNP
SDHYAPQTTSYDYDAILDEAGHPTPKFALMRDAIARVTGVQPPALPAPIATTTLPDTPLRESASLWDNLPAPIAIDTPQP
MEQFGQDYGYILYRTTVTGPRKGPLYLGDVRDVARVYVDQRPVGSVERRLQQVSLDVEIPAGQHTLDVLVENSGRINYGT
RMADGRAGLVDPVVLDNRQLTGWQAFPLPMRTPDSIRGWTRKAVQGPAFHRGTLRIGTPTDTYLDMRAFGKGFAWANGVN
LGRHWNIGPQTALYFPAPFQRKGDNTVVVFDLDDVATPSVRGLKQQVWLKPKE
>Mature_613_residues
MLRTTLAPLVLALAFALPITGTAAETERWPNFGTQGTQFVRDGKPYQLLSGAIHFQRIPRAYWKDRLQKARALGLNTVET
YVFWNLVEPQQGQFDFSGHNDVAAFVREAAAQGLNVILRPGPYACAEWEAGGYPAWLFGKGNIRVRSRDPRFLAASQAYL
DALANQVQPLLNHNGGPIIAVQVENEYGSYADDHAYMADNRAMYVKAGFDKALLFTSDGADMLANGTLPDTLAVVNFAPG
EAKSAFDKLIKFRPDQPRMVGEYWAGWFDHWGKPHAATDARQQAEEFEWILRQGHSANLYMFIGGTSFGFMNGANFQNNP
SDHYAPQTTSYDYDAILDEAGHPTPKFALMRDAIARVTGVQPPALPAPIATTTLPDTPLRESASLWDNLPAPIAIDTPQP
MEQFGQDYGYILYRTTVTGPRKGPLYLGDVRDVARVYVDQRPVGSVERRLQQVSLDVEIPAGQHTLDVLVENSGRINYGT
RMADGRAGLVDPVVLDNRQLTGWQAFPLPMRTPDSIRGWTRKAVQGPAFHRGTLRIGTPTDTYLDMRAFGKGFAWANGVN
LGRHWNIGPQTALYFPAPFQRKGDNTVVVFDLDDVATPSVRGLKQQVWLKPKE

Specific function: Preferentially hydrolyzes beta(1->3) galactosyl linkages over beta(1->4) linkages [H]

COG id: COG1874

COG function: function code G; Beta-galactosidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 35 family [H]

Homologues:

Organism=Homo sapiens, GI31543093, Length=591, Percent_Identity=41.1167512690355, Blast_Score=407, Evalue=1e-113,
Organism=Homo sapiens, GI164519026, Length=585, Percent_Identity=38.4615384615385, Blast_Score=382, Evalue=1e-106,
Organism=Homo sapiens, GI119372308, Length=615, Percent_Identity=40.3252032520325, Blast_Score=382, Evalue=1e-106,
Organism=Homo sapiens, GI119372312, Length=597, Percent_Identity=41.0385259631491, Blast_Score=381, Evalue=1e-105,
Organism=Homo sapiens, GI40255043, Length=595, Percent_Identity=39.6638655462185, Blast_Score=377, Evalue=1e-104,
Organism=Homo sapiens, GI208022658, Length=396, Percent_Identity=36.3636363636364, Blast_Score=190, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI72000600, Length=597, Percent_Identity=33.8358458961474, Blast_Score=298, Evalue=5e-81,
Organism=Caenorhabditis elegans, GI17568491, Length=636, Percent_Identity=31.2893081761006, Blast_Score=263, Evalue=2e-70,
Organism=Drosophila melanogaster, GI24646169, Length=590, Percent_Identity=36.271186440678, Blast_Score=334, Evalue=9e-92,
Organism=Drosophila melanogaster, GI24582088, Length=634, Percent_Identity=33.2807570977918, Blast_Score=325, Evalue=8e-89,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008979
- InterPro:   IPR019801
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR001944 [H]

Pfam domain/function: PF01301 Glyco_hydro_35 [H]

EC number: =3.2.1.23 [H]

Molecular weight: Translated: 67968; Mature: 67968

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: PS01182 GLYCOSYL_HYDROL_F35

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRTTLAPLVLALAFALPITGTAAETERWPNFGTQGTQFVRDGKPYQLLSGAIHFQRIPR
CCCHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHH
AYWKDRLQKARALGLNTVETYVFWNLVEPQQGQFDFSGHNDVAAFVREAAAQGLNVILRP
HHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEECC
GPYACAEWEAGGYPAWLFGKGNIRVRSRDPRFLAASQAYLDALANQVQPLLNHNGGPIIA
CCCEEECCCCCCCEEEEEECCCEEEECCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCEEE
VQVENEYGSYADDHAYMADNRAMYVKAGFDKALLFTSDGADMLANGTLPDTLAVVNFAPG
EEECCCCCCCCCCCCEEECCCEEEEEECCCEEEEEECCCCHHEECCCCCCCEEEEEECCC
EAKSAFDKLIKFRPDQPRMVGEYWAGWFDHWGKPHAATDARQQAEEFEWILRQGHSANLY
CHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCEE
MFIGGTSFGFMNGANFQNNPSDHYAPQTTSYDYDAILDEAGHPTPKFALMRDAIARVTGV
EEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHCCC
QPPALPAPIATTTLPDTPLRESASLWDNLPAPIAIDTPQPMEQFGQDYGYILYRTTVTGP
CCCCCCCCCEECCCCCCCCCHHHHHHHCCCCCEEECCCCHHHHHCCCCCEEEEEEEECCC
RKGPLYLGDVRDVARVYVDQRPVGSVERRLQQVSLDVEIPAGQHTLDVLVENSGRINYGT
CCCCEEECCHHHHHHHHHCCCCCCHHHHHHHHHEEEEECCCCCCEEEEEEECCCCEECCC
RMADGRAGLVDPVVLDNRQLTGWQAFPLPMRTPDSIRGWTRKAVQGPAFHRGTLRIGTPT
EECCCCCCCCCCEEECCCCCCCEEECCCCCCCCHHHHHHHHHHHCCCCEECCEEEECCCC
DTYLDMRAFGKGFAWANGVNLGRHWNIGPQTALYFPAPFQRKGDNTVVVFDLDDVATPSV
CCHHHHHHHCCCCCEECCCCCCCCCCCCCCCEEEECCCCCCCCCCEEEEEECCCCCCCHH
RGLKQQVWLKPKE
HHHHHHHCCCCCC
>Mature Secondary Structure
MLRTTLAPLVLALAFALPITGTAAETERWPNFGTQGTQFVRDGKPYQLLSGAIHFQRIPR
CCCHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHH
AYWKDRLQKARALGLNTVETYVFWNLVEPQQGQFDFSGHNDVAAFVREAAAQGLNVILRP
HHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEECC
GPYACAEWEAGGYPAWLFGKGNIRVRSRDPRFLAASQAYLDALANQVQPLLNHNGGPIIA
CCCEEECCCCCCCEEEEEECCCEEEECCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCEEE
VQVENEYGSYADDHAYMADNRAMYVKAGFDKALLFTSDGADMLANGTLPDTLAVVNFAPG
EEECCCCCCCCCCCCEEECCCEEEEEECCCEEEEEECCCCHHEECCCCCCCEEEEEECCC
EAKSAFDKLIKFRPDQPRMVGEYWAGWFDHWGKPHAATDARQQAEEFEWILRQGHSANLY
CHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCEE
MFIGGTSFGFMNGANFQNNPSDHYAPQTTSYDYDAILDEAGHPTPKFALMRDAIARVTGV
EEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHCCC
QPPALPAPIATTTLPDTPLRESASLWDNLPAPIAIDTPQPMEQFGQDYGYILYRTTVTGP
CCCCCCCCCEECCCCCCCCCHHHHHHHCCCCCEEECCCCHHHHHCCCCCEEEEEEEECCC
RKGPLYLGDVRDVARVYVDQRPVGSVERRLQQVSLDVEIPAGQHTLDVLVENSGRINYGT
CCCCEEECCHHHHHHHHHCCCCCCHHHHHHHHHEEEEECCCCCCEEEEEEECCCCEECCC
RMADGRAGLVDPVVLDNRQLTGWQAFPLPMRTPDSIRGWTRKAVQGPAFHRGTLRIGTPT
EECCCCCCCCCCEEECCCCCCCEEECCCCCCCCHHHHHHHHHHHCCCCEECCEEEECCCC
DTYLDMRAFGKGFAWANGVNLGRHWNIGPQTALYFPAPFQRKGDNTVVVFDLDDVATPSV
CCHHHHHHHCCCCCEECCCCCCCCCCCCCCCEEEECCCCCCCCCCEEEEEECCCCCCCHH
RGLKQQVWLKPKE
HHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8563148 [H]