Click here to switch to the map view.

The map label for this gene is ptsK

Identifier: 21243702

GI number: 21243702

Start: 3476557

End: 3477507

Strand: Direct

Name: ptsK

Synonym: XAC2975

Alternate gene names: 21243702

Gene position: 3476557-3477507 (Clockwise)

Preceding gene: 21243701

Following gene: 21243703

Centisome position: 67.17

GC content: 65.3

Gene sequence:

>951_bases
ATGAATACCAGCATCACCGCACGCGAACTGTTCGACCAGCAGCGCGACAAGCTGGCCCTGCGCTGGGTCGCCGGCCCCAA
GGGCGAGCACCGCGAGATCCAGGCCAACAGCAACAACGCACGGCGCCCGTCGCTGGCCGGCTACCTCAATGTGATCTATC
CCAACAAGGTGCAGATCCTGGGCACCGAGGAACTGGCCTGGCTGGACTCGCTGGATGCGCGGCAGCGCTGGGAAACCATC
GAAAAGATCATCCAGGTGCAACCGCTGGCGCTGGCGATCAGCAAGAACCAGTCATGCCCGGAAGATCTGCGCGCGGCGGC
GGACGAATCCAATACGCCGCTGTGGATCTCGTCCAAGCGCGGCCACGAACTGCTCAACCACCTCTCCTACCATCTGGCGC
GCACGCTGGCGCCGCGGGTCACCTTGCATGGCGTGTTCATGGAGATCTACTCGATCGGCGTGCTGATCACCGGCGAAGCC
GGCTCGGGCAAGAGCGAGCTGGCGCTGGAACTGCTCAGCCGCGGTCACCGGCTGGTGGCCGACGATGCCCCCGAGTTCAC
CCAGATCGCGCCCGACGTGCTCGACGGCACCTGCCCCGAATTGCTCCAGGATTTGCTGGAAGTACGCGGCCTGGGCGTCT
TGAACGTACGCGACATGTTCGGCGACACCGCGGTGAAGAAGAACAAGTACCTGCGCCTGATCGTACACCTGACCCGGCCG
ATGACCGAGCCGACGCCGTCCGGCTACGAGCGTCTGACCGGCGATTCGGGCAGCCGCCATGTGCTGGACCTGGACGTCCC
GCTGATCACCCTGCCGGTCATGCCCGGCCGCAATCTGGCCGTGCTGACCGAAGCGGCGACCCGGCTGCATATCCTGCGCA
CCAAAGGCATCGACCCGGCAGCGATGTTCATCGCCCGCCATAGCAACCTGCTGGAGCGACGCACGCCATGA

Upstream 100 bases:

>100_bases
TCTCCGATGCCGACTTCCGTCGGAACTTGCGCACCGCACCCAACGCCGATGCCCTGATGGCGCTGCTGGCCGACGTGCCG
CCCGCGCAGGCGAGCGCGGC

Downstream 100 bases:

>100_bases
GTATCGCGCCCTCCACGCTGATGATCGTGAGCGGGCTATCCGGCTCGGGCAAATCGGTCGCGCTGAAGACCTTCGAAGAC
CTGGACTACTATTGCTCGGA

Product: HPr kinase/phosphorylase

Products: NA

Alternate protein names: HPrK/P; HPr(Ser) kinase/phosphorylase

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MNTSITARELFDQQRDKLALRWVAGPKGEHREIQANSNNARRPSLAGYLNVIYPNKVQILGTEELAWLDSLDARQRWETI
EKIIQVQPLALAISKNQSCPEDLRAAADESNTPLWISSKRGHELLNHLSYHLARTLAPRVTLHGVFMEIYSIGVLITGEA
GSGKSELALELLSRGHRLVADDAPEFTQIAPDVLDGTCPELLQDLLEVRGLGVLNVRDMFGDTAVKKNKYLRLIVHLTRP
MTEPTPSGYERLTGDSGSRHVLDLDVPLITLPVMPGRNLAVLTEAATRLHILRTKGIDPAAMFIARHSNLLERRTP

Sequences:

>Translated_316_residues
MNTSITARELFDQQRDKLALRWVAGPKGEHREIQANSNNARRPSLAGYLNVIYPNKVQILGTEELAWLDSLDARQRWETI
EKIIQVQPLALAISKNQSCPEDLRAAADESNTPLWISSKRGHELLNHLSYHLARTLAPRVTLHGVFMEIYSIGVLITGEA
GSGKSELALELLSRGHRLVADDAPEFTQIAPDVLDGTCPELLQDLLEVRGLGVLNVRDMFGDTAVKKNKYLRLIVHLTRP
MTEPTPSGYERLTGDSGSRHVLDLDVPLITLPVMPGRNLAVLTEAATRLHILRTKGIDPAAMFIARHSNLLERRTP
>Mature_316_residues
MNTSITARELFDQQRDKLALRWVAGPKGEHREIQANSNNARRPSLAGYLNVIYPNKVQILGTEELAWLDSLDARQRWETI
EKIIQVQPLALAISKNQSCPEDLRAAADESNTPLWISSKRGHELLNHLSYHLARTLAPRVTLHGVFMEIYSIGVLITGEA
GSGKSELALELLSRGHRLVADDAPEFTQIAPDVLDGTCPELLQDLLEVRGLGVLNVRDMFGDTAVKKNKYLRLIVHLTRP
MTEPTPSGYERLTGDSGSRHVLDLDVPLITLPVMPGRNLAVLTEAATRLHILRTKGIDPAAMFIARHSNLLERRTP

Specific function: Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-pr

COG id: COG1493

COG function: function code T; Serine kinase of the HPr protein, regulates carbohydrate metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HPrK/P family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HPRK_XANAC (Q8PIC3)

Other databases:

- EMBL:   AE008923
- RefSeq:   NP_643284.1
- ProteinModelPortal:   Q8PIC3
- SMR:   Q8PIC3
- GeneID:   1157046
- GenomeReviews:   AE008923_GR
- KEGG:   xac:XAC2975
- NMPDR:   fig|190486.1.peg.2928
- HOGENOM:   HBG566466
- OMA:   IHGVLVD
- ProtClustDB:   PRK05428
- BioCyc:   XAXO190486:XAC2975-MONOMER
- HAMAP:   MF_01249
- InterPro:   IPR003755
- InterPro:   IPR011104
- InterPro:   IPR011126

Pfam domain/function: PF07475 Hpr_kinase_C; PF02603 Hpr_kinase_N

EC number: NA

Molecular weight: Translated: 35171; Mature: 35171

Theoretical pI: Translated: 7.37; Mature: 7.37

Prosite motif: NA

Important sites: ACT_SITE 143-143 ACT_SITE 164-164 ACT_SITE 182-182 ACT_SITE 251-251

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTSITARELFDQQRDKLALRWVAGPKGEHREIQANSNNARRPSLAGYLNVIYPNKVQIL
CCCCCHHHHHHHHHHHHEEEEEECCCCCCCCEEEECCCCCCCCCHHHEEEEECCCEEEEE
GTEELAWLDSLDARQRWETIEKIIQVQPLALAISKNQSCPEDLRAAADESNTPLWISSKR
ECHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHCCCCCCCEEEECCC
GHELLNHLSYHLARTLAPRVTLHGVFMEIYSIGVLITGEAGSGKSELALELLSRGHRLVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHCCCEEEC
DDAPEFTQIAPDVLDGTCPELLQDLLEVRGLGVLNVRDMFGDTAVKKNKYLRLIVHLTRP
CCCCHHHHHCHHHHCCCHHHHHHHHHHHHCCCEEEHHHHHCCHHHCCCCCEEEEEEECCC
MTEPTPSGYERLTGDSGSRHVLDLDVPLITLPVMPGRNLAVLTEAATRLHILRTKGIDPA
CCCCCCCCHHHHCCCCCCCEEEEECCCEEEEECCCCCCEEEEHHHHHHEEEEEECCCCHH
AMFIARHSNLLERRTP
HHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNTSITARELFDQQRDKLALRWVAGPKGEHREIQANSNNARRPSLAGYLNVIYPNKVQIL
CCCCCHHHHHHHHHHHHEEEEEECCCCCCCCEEEECCCCCCCCCHHHEEEEECCCEEEEE
GTEELAWLDSLDARQRWETIEKIIQVQPLALAISKNQSCPEDLRAAADESNTPLWISSKR
ECHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHCCCCCCCEEEECCC
GHELLNHLSYHLARTLAPRVTLHGVFMEIYSIGVLITGEAGSGKSELALELLSRGHRLVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHCCCEEEC
DDAPEFTQIAPDVLDGTCPELLQDLLEVRGLGVLNVRDMFGDTAVKKNKYLRLIVHLTRP
CCCCHHHHHCHHHHCCCHHHHHHHHHHHHCCCEEEHHHHHCCHHHCCCCCEEEEEEECCC
MTEPTPSGYERLTGDSGSRHVLDLDVPLITLPVMPGRNLAVLTEAATRLHILRTKGIDPA
CCCCCCCCHHHHCCCCCCCEEEEECCCEEEEECCCCCCEEEEHHHHHHEEEEEECCCCHH
AMFIARHSNLLERRTP
HHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217