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The map label for this gene is murA

Identifier: 21243692

GI number: 21243692

Start: 3468970

End: 3470244

Strand: Reverse

Name: murA

Synonym: XAC2965

Alternate gene names: 21243692

Gene position: 3470244-3468970 (Counterclockwise)

Preceding gene: 21243693

Following gene: 21243691

Centisome position: 67.05

GC content: 66.35

Gene sequence:

>1275_bases
ATGGCAAAAATCGTAGTGACCGGCGGCCAAGCGCTGCATGGCGAAGTCCATATTTCCGGTGCCAAGAACGCAGTGCTGCC
GATCCTGTGCGCGACCCTGCTGGCCGACGCGCCAGTGGAAATCAGCAACGTGCCGCATCTGCACGACGTGATCACCACGG
TGAAATTGCTCAGCGAGCTGGGCGCCGAGGTCACCATCGACGAAGGCACGCTGGCCAAGGGCCGCTCGATGCTGGTCGAC
CCGCGCTCGGTCACCCATCAGGTTGCGCCGTATGAGCTGGTCAAGACCATGCGTGCCTCGATCCTGGTGTTGGGCCCGCT
GCTGGCGCGCTACGGCACTGCAGAAGTCTCGCTGCCCGGCGGTTGCGCGATCGGTTCGCGCCCGGTGGACCAGCACATCA
AGGGCCTGCAGGCACTGGGTGCCGACATCAGCGTGGAAAACGGCTACATCAAGGCCACCAGCAATGGCCGCCTGAAGGGT
GCTCGCTACGTATTCGACATGGTCAGCGTCACCGGCACCGAGAACGTGCTGATGGCTGCGGTGCTCGCCGAGGGCACCAC
GGTGCTGGAAAATGCGGCGATGGAGCCGGAAGTCACCGACCTGGCCGACTGCCTGATCGCACTCGGTGCGCGGATCGAAG
GCGCCGGCACCCCGCGCATCGTGGTGCAAGGCGTCGAGCGGCTGGGCGGCGGGCACCATGCGGTGCTGCCGGACCGCATC
GAAACCGGTACCTTCCTGGTCGCTGCGGCGATGACCGGCGGCAGCGTCACCGTGCGCCGCGCGCGCCCGGAAACGCTGGA
CGCAGTACTGGACAAGCTGACCGAGGCTGGCGCCACCATCACCACCACCGCCGACAGCATCACGCTGGACATGCAAGGCA
AGCGCCCGCGCGCGGTCAGCCTGACCACCGCGCCGTACCCGGCGTTTCCCACCGACATGCAGGCGCAATTCATGGCGCTC
AACTGCGTGGCCGATGGCGTGGGCGTGATCAACGAAACCATCTTCGAAAACCGCTTCATGCACGTCAACGAGCTGCTGCG
CCTGGGCGCGGATATCCAGGTCGAAGGTCATACCGCCATCGTGCGCGGTGCCGAACGCCTGAGCGGCGCGCCGGTGATGG
CGACCGACCTGCGCGCGTCGGCGTCGCTGATCCTGGCAGGCCTGGTCGCCGATGGCGACACCACCATCGATCGCATCTAC
CACCTGGACCGTGGCTACGAAAACATCGAGGAGAAGCTGGGGGCGCTGGGCGCGACCATCCAGCGCACCGCATGA

Upstream 100 bases:

>100_bases
CGATCCCCGGCGCCACCACGCGCCGCGTGCACCATGATCGATACGTCCCGCACTTCATTCCCCCGACATCCCTTCTACTT
TCGGATTTCTTAAGATTCCC

Downstream 100 bases:

>100_bases
TCCTGCGCGGCCGTTTCACCACCCGGCGCAAGATCCTGCTGGGTGTGATCGTGCTGATCCTGGCATGGCTGACCTATGCC
TGGAGCGTGGGCATGGCCAT

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT

Number of amino acids: Translated: 424; Mature: 423

Protein sequence:

>424_residues
MAKIVVTGGQALHGEVHISGAKNAVLPILCATLLADAPVEISNVPHLHDVITTVKLLSELGAEVTIDEGTLAKGRSMLVD
PRSVTHQVAPYELVKTMRASILVLGPLLARYGTAEVSLPGGCAIGSRPVDQHIKGLQALGADISVENGYIKATSNGRLKG
ARYVFDMVSVTGTENVLMAAVLAEGTTVLENAAMEPEVTDLADCLIALGARIEGAGTPRIVVQGVERLGGGHHAVLPDRI
ETGTFLVAAAMTGGSVTVRRARPETLDAVLDKLTEAGATITTTADSITLDMQGKRPRAVSLTTAPYPAFPTDMQAQFMAL
NCVADGVGVINETIFENRFMHVNELLRLGADIQVEGHTAIVRGAERLSGAPVMATDLRASASLILAGLVADGDTTIDRIY
HLDRGYENIEEKLGALGATIQRTA

Sequences:

>Translated_424_residues
MAKIVVTGGQALHGEVHISGAKNAVLPILCATLLADAPVEISNVPHLHDVITTVKLLSELGAEVTIDEGTLAKGRSMLVD
PRSVTHQVAPYELVKTMRASILVLGPLLARYGTAEVSLPGGCAIGSRPVDQHIKGLQALGADISVENGYIKATSNGRLKG
ARYVFDMVSVTGTENVLMAAVLAEGTTVLENAAMEPEVTDLADCLIALGARIEGAGTPRIVVQGVERLGGGHHAVLPDRI
ETGTFLVAAAMTGGSVTVRRARPETLDAVLDKLTEAGATITTTADSITLDMQGKRPRAVSLTTAPYPAFPTDMQAQFMAL
NCVADGVGVINETIFENRFMHVNELLRLGADIQVEGHTAIVRGAERLSGAPVMATDLRASASLILAGLVADGDTTIDRIY
HLDRGYENIEEKLGALGATIQRTA
>Mature_423_residues
AKIVVTGGQALHGEVHISGAKNAVLPILCATLLADAPVEISNVPHLHDVITTVKLLSELGAEVTIDEGTLAKGRSMLVDP
RSVTHQVAPYELVKTMRASILVLGPLLARYGTAEVSLPGGCAIGSRPVDQHIKGLQALGADISVENGYIKATSNGRLKGA
RYVFDMVSVTGTENVLMAAVLAEGTTVLENAAMEPEVTDLADCLIALGARIEGAGTPRIVVQGVERLGGGHHAVLPDRIE
TGTFLVAAAMTGGSVTVRRARPETLDAVLDKLTEAGATITTTADSITLDMQGKRPRAVSLTTAPYPAFPTDMQAQFMALN
CVADGVGVINETIFENRFMHVNELLRLGADIQVEGHTAIVRGAERLSGAPVMATDLRASASLILAGLVADGDTTIDRIYH
LDRGYENIEEKLGALGATIQRTA

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily

Homologues:

Organism=Escherichia coli, GI1789580, Length=422, Percent_Identity=63.0331753554502, Blast_Score=521, Evalue=1e-149,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURA_XANAC (Q8PID3)

Other databases:

- EMBL:   AE008923
- RefSeq:   NP_643274.1
- ProteinModelPortal:   Q8PID3
- SMR:   Q8PID3
- GeneID:   1157036
- GenomeReviews:   AE008923_GR
- KEGG:   xac:XAC2965
- NMPDR:   fig|190486.1.peg.2918
- HOGENOM:   HBG482701
- OMA:   MVKTMRA
- ProtClustDB:   PRK09369
- BioCyc:   XAXO190486:XAC2965-MONOMER
- BRENDA:   2.5.1.7
- GO:   GO:0005737
- HAMAP:   MF_00111
- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750
- Gene3D:   G3DSA:3.65.10.10
- PANTHER:   PTHR21090:SF4
- TIGRFAMs:   TIGR01072

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.7

Molecular weight: Translated: 44442; Mature: 44311

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: ACT_SITE 122-122

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKIVVTGGQALHGEVHISGAKNAVLPILCATLLADAPVEISNVPHLHDVITTVKLLSEL
CEEEEEECCCEEECEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHC
GAEVTIDEGTLAKGRSMLVDPRSVTHQVAPYELVKTMRASILVLGPLLARYGTAEVSLPG
CCEEEECCCCCCCCCCEEECCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCC
GCAIGSRPVDQHIKGLQALGADISVENGYIKATSNGRLKGARYVFDMVSVTGTENVLMAA
CCCCCCCCHHHHHHHHHHHCCCEEECCCEEEECCCCCCCHHHHHEEHHHHCCCCHHHHHH
VLAEGTTVLENAAMEPEVTDLADCLIALGARIEGAGTPRIVVQGVERLGGGHHAVLPDRI
HHHCCCHHHHHCCCCCCHHHHHHHHHHHCCEECCCCCCHHHHHHHHHHCCCCEEECCCCC
ETGTFLVAAAMTGGSVTVRRARPETLDAVLDKLTEAGATITTTADSITLDMQGKRPRAVS
CCCCEEEEEEECCCEEEEECCCCHHHHHHHHHHHHCCCEEEEECCEEEEEECCCCCCEEE
LTTAPYPAFPTDMQAQFMALNCVADGVGVINETIFENRFMHVNELLRLGADIQVEGHTAI
EECCCCCCCCCCCHHHHEEEHHHHCCHHHHHHHHHHCCCHHHHHHHHCCCCEEECCCHHE
VRGAERLSGAPVMATDLRASASLILAGLVADGDTTIDRIYHLDRGYENIEEKLGALGATI
EECHHHHCCCCEEEHHHHHHHHEEEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHCCHH
QRTA
CCCC
>Mature Secondary Structure 
AKIVVTGGQALHGEVHISGAKNAVLPILCATLLADAPVEISNVPHLHDVITTVKLLSEL
EEEEEECCCEEECEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHC
GAEVTIDEGTLAKGRSMLVDPRSVTHQVAPYELVKTMRASILVLGPLLARYGTAEVSLPG
CCEEEECCCCCCCCCCEEECCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCC
GCAIGSRPVDQHIKGLQALGADISVENGYIKATSNGRLKGARYVFDMVSVTGTENVLMAA
CCCCCCCCHHHHHHHHHHHCCCEEECCCEEEECCCCCCCHHHHHEEHHHHCCCCHHHHHH
VLAEGTTVLENAAMEPEVTDLADCLIALGARIEGAGTPRIVVQGVERLGGGHHAVLPDRI
HHHCCCHHHHHCCCCCCHHHHHHHHHHHCCEECCCCCCHHHHHHHHHHCCCCEEECCCCC
ETGTFLVAAAMTGGSVTVRRARPETLDAVLDKLTEAGATITTTADSITLDMQGKRPRAVS
CCCCEEEEEEECCCEEEEECCCCHHHHHHHHHHHHCCCEEEEECCEEEEEECCCCCCEEE
LTTAPYPAFPTDMQAQFMALNCVADGVGVINETIFENRFMHVNELLRLGADIQVEGHTAI
EECCCCCCCCCCCHHHHEEEHHHHCCHHHHHHHHHHCCCHHHHHHHHCCCCEEECCCHHE
VRGAERLSGAPVMATDLRASASLILAGLVADGDTTIDRIYHLDRGYENIEEKLGALGATI
EECHHHHCCCCEEEHHHHHHHHEEEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHCCHH
QRTA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12024217