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The map label for this gene is lytH [H]

Identifier: 21243655

GI number: 21243655

Start: 3435092

End: 3435709

Strand: Direct

Name: lytH [H]

Synonym: XAC2928

Alternate gene names: 21243655

Gene position: 3435092-3435709 (Clockwise)

Preceding gene: 21243654

Following gene: 21243656

Centisome position: 66.37

GC content: 67.64

Gene sequence:

>618_bases
GTGCCTGTGACCGGTCCGTCGAACACCCCGTCGCCACCACACCGAGTCTCCACACCTAGCCGCGCACGTCGGCTGCGCAG
CATCGTTATCTCGATTGCGCTGTTGTGCGTGCTGGCGGTGGCCGCGCGCTGGGCCTGGCAGCTGCCGATCGCCCATCAGC
TCCATACCAGCTGGGAGCTGTCGCAAATGCCGCCGCCTGCGCAGTTGCATGTGCCGGTGGAAGGCGTGCGTGCGCGACAG
ATTGCCGACACCTTTGGCGCACCCCGTGGCCGCGACCGCACGCACGCGGGCGTGGATATCTTCGCGCCACGCGGTACATC
GGTGGTCGCGGCAACGCGCGGCGTGGTCAGCGCCATCCGCGACCAGGGCCTGGGCGGAAAACAGGTCTGGCTCCTGGGTC
CGGCGATGGAACGGCATTACTACGCGCATCTTGACGACTGGGCTGCCGGCCTAGCAGTAGGCGATGTGGTCGAGCCCGGC
ACCCTGCTTGGCAAGGTCGGCACCACCGGCAATGCGCGCGGCACGCCGCCACACCTGCACTATGGTGTCTATGGACGCAA
CGGTGCGTACGATCCGCTGCCGCTTCTGCGCAAACCCGCCGCACAGCCAGCAAACTGA

Upstream 100 bases:

>100_bases
CGGCCCACGGGCCGTCTTTTTTTTGCCATCGCGCCGCGATGTGCAGCACATACCGCTCATCGGCACTGCCCTACCCTGCA
TGCTGATTCGCCATCTGCAG

Downstream 100 bases:

>100_bases
GCACGTTGGAACACTGCGTCATGGGCCACCCTATCGAGACGGTTGCGTCCTGCGCCTATGGTGAGCACAGCCCAGAACGA
CGCGCCCCATATGTCCCGCA

Product: peptidase

Products: NA

Alternate protein names: Peptidoglycan hydrolase; Sporulation-specific endopeptidase [H]

Number of amino acids: Translated: 205; Mature: 204

Protein sequence:

>205_residues
MPVTGPSNTPSPPHRVSTPSRARRLRSIVISIALLCVLAVAARWAWQLPIAHQLHTSWELSQMPPPAQLHVPVEGVRARQ
IADTFGAPRGRDRTHAGVDIFAPRGTSVVAATRGVVSAIRDQGLGGKQVWLLGPAMERHYYAHLDDWAAGLAVGDVVEPG
TLLGKVGTTGNARGTPPHLHYGVYGRNGAYDPLPLLRKPAAQPAN

Sequences:

>Translated_205_residues
MPVTGPSNTPSPPHRVSTPSRARRLRSIVISIALLCVLAVAARWAWQLPIAHQLHTSWELSQMPPPAQLHVPVEGVRARQ
IADTFGAPRGRDRTHAGVDIFAPRGTSVVAATRGVVSAIRDQGLGGKQVWLLGPAMERHYYAHLDDWAAGLAVGDVVEPG
TLLGKVGTTGNARGTPPHLHYGVYGRNGAYDPLPLLRKPAAQPAN
>Mature_204_residues
PVTGPSNTPSPPHRVSTPSRARRLRSIVISIALLCVLAVAARWAWQLPIAHQLHTSWELSQMPPPAQLHVPVEGVRARQI
ADTFGAPRGRDRTHAGVDIFAPRGTSVVAATRGVVSAIRDQGLGGKQVWLLGPAMERHYYAHLDDWAAGLAVGDVVEPGT
LLGKVGTTGNARGTPPHLHYGVYGRNGAYDPLPLLRKPAAQPAN

Specific function: L-Ala--D-Glu endopeptidase involved in production of single L-alanine side chains from tetrapeptides in the spore cortex peptidoglycan. Therefore, is required for the endospore cortex maturation [H]

COG id: COG0739

COG function: function code M; Membrane proteins related to metalloendopeptidases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M23B family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR016047 [H]

Pfam domain/function: PF01551 Peptidase_M23 [H]

EC number: NA

Molecular weight: Translated: 21900; Mature: 21769

Theoretical pI: Translated: 11.04; Mature: 11.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVTGPSNTPSPPHRVSTPSRARRLRSIVISIALLCVLAVAARWAWQLPIAHQLHTSWEL
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCC
SQMPPPAQLHVPVEGVRARQIADTFGAPRGRDRTHAGVDIFAPRGTSVVAATRGVVSAIR
CCCCCCCEEECCHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCEEEHHHHHHHHHHH
DQGLGGKQVWLLGPAMERHYYAHLDDWAAGLAVGDVVEPGTLLGKVGTTGNARGTPPHLH
HCCCCCCEEEEECCHHHHHEEHHHHHHHHHHHHCCCCCCCHHEECCCCCCCCCCCCCCEE
YGVYGRNGAYDPLPLLRKPAAQPAN
EEECCCCCCCCCCHHHHCCCCCCCC
>Mature Secondary Structure 
PVTGPSNTPSPPHRVSTPSRARRLRSIVISIALLCVLAVAARWAWQLPIAHQLHTSWEL
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCC
SQMPPPAQLHVPVEGVRARQIADTFGAPRGRDRTHAGVDIFAPRGTSVVAATRGVVSAIR
CCCCCCCEEECCHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCEEEHHHHHHHHHHH
DQGLGGKQVWLLGPAMERHYYAHLDDWAAGLAVGDVVEPGTLLGKVGTTGNARGTPPHLH
HCCCCCCEEEEECCHHHHHEEHHHHHHHHHHHHCCCCCCCHHEECCCCCCCCCCCCCCEE
YGVYGRNGAYDPLPLLRKPAAQPAN
EEECCCCCCCCCCHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 12813075 [H]