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The map label for this gene is aspA [H]

Identifier: 21243558

GI number: 21243558

Start: 3319903

End: 3321714

Strand: Direct

Name: aspA [H]

Synonym: XAC2831

Alternate gene names: 21243558

Gene position: 3319903-3321714 (Clockwise)

Preceding gene: 21243557

Following gene: 21243559

Centisome position: 64.15

GC content: 62.8

Gene sequence:

>1812_bases
ATGAACTCTCTTCGCAGGCGACCTCTCGCGCTGTTGATAGCGGTCCTCCTGACCGGCGGCACGCCGCTGTCGGTACTTGC
TGCCACCCAGGCAACGGCTGCCACCACCCCGGCCACTACCAGCGCCAAAGCGAAAGCCACAGGCAACGACCCATTACTGC
GGTACCAGTGGCATATCTCCAACCAGGGGCAGGCCGTGATCGGCGACAGCCGTCCGGTCGCTGGCGTGGACATGGATGTG
GACATCCTGCATGCCCTGGACATTCGCGGCCGCGGCGTGCGGGTCGGCGTGGTGGACGATGGGCTGGAATTGGGCCATGA
AGATCTGGCAGACAACATCCTGCCAAACGGGTCGCACAATTTCGGCGATGGGTCGCACGACACCACGCCGATCGATCCGA
GTAACGGGCACGGGACGTCCGTCGCCGGCATCATCGGTGCGGTGGGCTGGAATGGCCGCGGCGGACGCGGCGTGGCGCCA
GAAGTGCAGCTGGCAGGATTCGACGTTTTTGCGCGCGATTCTTCGGTCACCGATGCCAGCATCAGGTATGCATGGGGCGA
TGGCCCGGAGGCGCGCAATATCGATGTCTTCAACAACAGCTGGGGGTCGGTTGCCCCGTTCTACTTTGATTTTTCTGTGG
AGGACCAGCGCACCTGGCAAGCATTGATGGGTTCGACACGTGGCGGCCTTGGCGGCATTTATGTCAAATCCGCTGGCAAT
AGCTTCCTGCGCTTCCTTGAGCCCGACGAGAACGGAAACCCCGTCAATGTCTGCAGCGAACAATCGCGCGCATTGCAGGT
CGGCTGCTCGCTGGCCAACATCGATCCCTTCGCAAATCTGCCCGGAACCATCGTCGTGGCCAGCCTGAATGCCAAGGGCA
CCCGTGCCTCGTATTCGTCCACAGGCTCTGCGTTGTGGGTTTCCGGTCTTGGCGGCGAGTTCGGCCGTCAACGCAAGTTC
TATCCCGACGCAGCGTCCACCTTTTTCCCGGATTCGGCGCCCTATGCCTACGATCCGGCGATTGTCACCACCGATCTCAG
CGGCTGCACAGCGGGCGAGAACGTCGAAGATCCCGACGTGGTCTACAACGCATTGGATGGCAGCAAGTCGAAGATCGATG
CGTCGTGCAACTACAACGCGATCATGAACGGGACCTCGGCCGCAGCGCCTACCGTGTCTGGCGTGGCTGCGTTGATCCTC
GGTGCCAATGCGAGCCTGAGCGCACGCGACGTCAAATATATTCTTGCGACAACCGCGCGCCAGATCGACCCATGGCAGCC
GCGGGTGGTCTACCAGGGCAGCGTGATCGATCCGGGCTGGATCACCAACGCAGCCGGGCACCGTTTCAGCAATTGGTACG
GCTTCGGTCTGGCCGATGCCGCGGCCGCGGTCTACAAGGCGCGCTATTTCACACCGCTGCCGCCCATGCGTGATACCCAG
TGGGTCAGCTCCACCGATGCGGCCAGCCAGATCGGTGGCCCGGCGCGCCCGGGCAAGCTGCGCATCCGTGTGCAGCAGGC
GATGAAGGTGGAAGCGGTGCAGCTGTCGCTGCAGTCGGCGCACAAGACGCCGTCCAACCTGCGTGTGGTGCTGGTGTCCC
CGAGCGGGACGCGCAGCGTCGTCGCCACGCCGTTTTCCGTCCTGGATCCGGCTGCTTATGCGCAGACGGGGTTCTATATC
GACCTGACCTCCAGCAATGCGTTTCTGGACGAGAAATCGCGCGGCATCTGGACCCTGGAAGTGACCGACATGACCGATCC
CAGGAGCACTGTCGCACTCAACGCTTTCAAACTTCGCATCGTGGGGCACTGA

Upstream 100 bases:

>100_bases
CTTCGTGGAGTGGAGCAGTTGCAAGGGCCGATCGCGCGGTTGGCCTGACGGAGGACTGCGTCACTCGACGGCGCCCACCA
TTCGACTGGAATCAAACGGA

Downstream 100 bases:

>100_bases
TATGAAACCGACGATTCTTGCTTGCCTGCTGACGCTATCACTCGCCGCAACCGGTGCTGCCCAGGCAGCGCAATACATGG
ACGCCAAGACCCTGCGTGCG

Product: extracellular serine protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 603; Mature: 603

Protein sequence:

>603_residues
MNSLRRRPLALLIAVLLTGGTPLSVLAATQATAATTPATTSAKAKATGNDPLLRYQWHISNQGQAVIGDSRPVAGVDMDV
DILHALDIRGRGVRVGVVDDGLELGHEDLADNILPNGSHNFGDGSHDTTPIDPSNGHGTSVAGIIGAVGWNGRGGRGVAP
EVQLAGFDVFARDSSVTDASIRYAWGDGPEARNIDVFNNSWGSVAPFYFDFSVEDQRTWQALMGSTRGGLGGIYVKSAGN
SFLRFLEPDENGNPVNVCSEQSRALQVGCSLANIDPFANLPGTIVVASLNAKGTRASYSSTGSALWVSGLGGEFGRQRKF
YPDAASTFFPDSAPYAYDPAIVTTDLSGCTAGENVEDPDVVYNALDGSKSKIDASCNYNAIMNGTSAAAPTVSGVAALIL
GANASLSARDVKYILATTARQIDPWQPRVVYQGSVIDPGWITNAAGHRFSNWYGFGLADAAAAVYKARYFTPLPPMRDTQ
WVSSTDAASQIGGPARPGKLRIRVQQAMKVEAVQLSLQSAHKTPSNLRVVLVSPSGTRSVVATPFSVLDPAAYAQTGFYI
DLTSSNAFLDEKSRGIWTLEVTDMTDPRSTVALNAFKLRIVGH

Sequences:

>Translated_603_residues
MNSLRRRPLALLIAVLLTGGTPLSVLAATQATAATTPATTSAKAKATGNDPLLRYQWHISNQGQAVIGDSRPVAGVDMDV
DILHALDIRGRGVRVGVVDDGLELGHEDLADNILPNGSHNFGDGSHDTTPIDPSNGHGTSVAGIIGAVGWNGRGGRGVAP
EVQLAGFDVFARDSSVTDASIRYAWGDGPEARNIDVFNNSWGSVAPFYFDFSVEDQRTWQALMGSTRGGLGGIYVKSAGN
SFLRFLEPDENGNPVNVCSEQSRALQVGCSLANIDPFANLPGTIVVASLNAKGTRASYSSTGSALWVSGLGGEFGRQRKF
YPDAASTFFPDSAPYAYDPAIVTTDLSGCTAGENVEDPDVVYNALDGSKSKIDASCNYNAIMNGTSAAAPTVSGVAALIL
GANASLSARDVKYILATTARQIDPWQPRVVYQGSVIDPGWITNAAGHRFSNWYGFGLADAAAAVYKARYFTPLPPMRDTQ
WVSSTDAASQIGGPARPGKLRIRVQQAMKVEAVQLSLQSAHKTPSNLRVVLVSPSGTRSVVATPFSVLDPAAYAQTGFYI
DLTSSNAFLDEKSRGIWTLEVTDMTDPRSTVALNAFKLRIVGH
>Mature_603_residues
MNSLRRRPLALLIAVLLTGGTPLSVLAATQATAATTPATTSAKAKATGNDPLLRYQWHISNQGQAVIGDSRPVAGVDMDV
DILHALDIRGRGVRVGVVDDGLELGHEDLADNILPNGSHNFGDGSHDTTPIDPSNGHGTSVAGIIGAVGWNGRGGRGVAP
EVQLAGFDVFARDSSVTDASIRYAWGDGPEARNIDVFNNSWGSVAPFYFDFSVEDQRTWQALMGSTRGGLGGIYVKSAGN
SFLRFLEPDENGNPVNVCSEQSRALQVGCSLANIDPFANLPGTIVVASLNAKGTRASYSSTGSALWVSGLGGEFGRQRKF
YPDAASTFFPDSAPYAYDPAIVTTDLSGCTAGENVEDPDVVYNALDGSKSKIDASCNYNAIMNGTSAAAPTVSGVAALIL
GANASLSARDVKYILATTARQIDPWQPRVVYQGSVIDPGWITNAAGHRFSNWYGFGLADAAAAVYKARYFTPLPPMRDTQ
WVSSTDAASQIGGPARPGKLRIRVQQAMKVEAVQLSLQSAHKTPSNLRVVLVSPSGTRSVVATPFSVLDPAAYAQTGFYI
DLTSSNAFLDEKSRGIWTLEVTDMTDPRSTVALNAFKLRIVGH

Specific function: Agent of furonculosis [H]

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

Organism=Homo sapiens, GI4505577, Length=587, Percent_Identity=25.8943781942078, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI20336180, Length=587, Percent_Identity=25.8943781942078, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI20336190, Length=565, Percent_Identity=26.3716814159292, Blast_Score=127, Evalue=4e-29,
Organism=Homo sapiens, GI20336182, Length=587, Percent_Identity=25.8943781942078, Blast_Score=126, Evalue=5e-29,
Organism=Homo sapiens, GI27894285, Length=565, Percent_Identity=26.1946902654867, Blast_Score=126, Evalue=5e-29,
Organism=Homo sapiens, GI20336184, Length=587, Percent_Identity=25.8943781942078, Blast_Score=126, Evalue=5e-29,
Organism=Homo sapiens, GI20336188, Length=565, Percent_Identity=26.3716814159292, Blast_Score=126, Evalue=6e-29,
Organism=Homo sapiens, GI76443679, Length=581, Percent_Identity=25.473321858864, Blast_Score=124, Evalue=3e-28,
Organism=Homo sapiens, GI4505579, Length=573, Percent_Identity=26.0034904013962, Blast_Score=122, Evalue=1e-27,
Organism=Homo sapiens, GI20336244, Length=552, Percent_Identity=27.536231884058, Blast_Score=117, Evalue=4e-26,
Organism=Homo sapiens, GI299523015, Length=566, Percent_Identity=25.2650176678445, Blast_Score=109, Evalue=7e-24,
Organism=Homo sapiens, GI20336246, Length=555, Percent_Identity=25.045045045045, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI20336248, Length=586, Percent_Identity=25.7679180887372, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI20336242, Length=203, Percent_Identity=33.0049261083744, Blast_Score=80, Evalue=6e-15,
Organism=Homo sapiens, GI295424143, Length=203, Percent_Identity=33.0049261083744, Blast_Score=79, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI71988321, Length=581, Percent_Identity=26.3339070567986, Blast_Score=117, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI71988315, Length=581, Percent_Identity=26.3339070567986, Blast_Score=117, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI71988301, Length=581, Percent_Identity=26.3339070567986, Blast_Score=117, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI71988297, Length=581, Percent_Identity=26.3339070567986, Blast_Score=117, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI71988312, Length=574, Percent_Identity=27.1777003484321, Blast_Score=117, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI71988308, Length=574, Percent_Identity=27.1777003484321, Blast_Score=116, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI25141268, Length=567, Percent_Identity=24.8677248677249, Blast_Score=102, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI71987206, Length=527, Percent_Identity=26.7552182163188, Blast_Score=97, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI71983555, Length=446, Percent_Identity=25.7847533632287, Blast_Score=92, Evalue=7e-19,
Organism=Saccharomyces cerevisiae, GI6324091, Length=573, Percent_Identity=23.7347294938918, Blast_Score=106, Evalue=9e-24,
Organism=Drosophila melanogaster, GI24642488, Length=553, Percent_Identity=27.124773960217, Blast_Score=126, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24642484, Length=553, Percent_Identity=27.124773960217, Blast_Score=126, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24642486, Length=553, Percent_Identity=27.124773960217, Blast_Score=126, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24642494, Length=552, Percent_Identity=26.6304347826087, Blast_Score=125, Evalue=8e-29,
Organism=Drosophila melanogaster, GI24642490, Length=552, Percent_Identity=26.6304347826087, Blast_Score=125, Evalue=8e-29,
Organism=Drosophila melanogaster, GI45555723, Length=552, Percent_Identity=26.6304347826087, Blast_Score=125, Evalue=8e-29,
Organism=Drosophila melanogaster, GI24642492, Length=552, Percent_Identity=26.6304347826087, Blast_Score=125, Evalue=8e-29,
Organism=Drosophila melanogaster, GI281360987, Length=552, Percent_Identity=26.6304347826087, Blast_Score=125, Evalue=9e-29,
Organism=Drosophila melanogaster, GI17136192, Length=549, Percent_Identity=26.0473588342441, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI281360985, Length=198, Percent_Identity=31.8181818181818, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24650058, Length=201, Percent_Identity=28.3582089552239, Blast_Score=73, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24650060, Length=201, Percent_Identity=28.3582089552239, Blast_Score=73, Evalue=6e-13,
Organism=Drosophila melanogaster, GI45553513, Length=201, Percent_Identity=28.3582089552239, Blast_Score=73, Evalue=6e-13,
Organism=Drosophila melanogaster, GI45553515, Length=201, Percent_Identity=28.3582089552239, Blast_Score=73, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24650056, Length=201, Percent_Identity=28.3582089552239, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI17864552, Length=203, Percent_Identity=28.0788177339901, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008979
- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500
- InterPro:   IPR002884 [H]

Pfam domain/function: PF01483 P_proprotein; PF00082 Peptidase_S8 [H]

EC number: NA

Molecular weight: Translated: 63689; Mature: 63689

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: PS00136 SUBTILASE_ASP ; PS00137 SUBTILASE_HIS ; PS00138 SUBTILASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSLRRRPLALLIAVLLTGGTPLSVLAATQATAATTPATTSAKAKATGNDPLLRYQWHIS
CCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCEEEECCCCCEEEEEEEEC
NQGQAVIGDSRPVAGVDMDVDILHALDIRGRGVRVGVVDDGLELGHEDLADNILPNGSHN
CCCCEEECCCCCCCCCCCCCEEEEEECCCCCCEEEEEECCCHHCCHHHHHHHCCCCCCCC
FGDGSHDTTPIDPSNGHGTSVAGIIGAVGWNGRGGRGVAPEVQLAGFDVFARDSSVTDAS
CCCCCCCCCCCCCCCCCCCCHHHHHEECCCCCCCCCCCCCCEEEECEEEEECCCCCCCCE
IRYAWGDGPEARNIDVFNNSWGSVAPFYFDFSVEDQRTWQALMGSTRGGLGGIYVKSAGN
EEEEECCCCCCCEEEEEECCCCCCCCEEEEEECCHHHHHHHHHCCCCCCCCEEEEECCCC
SFLRFLEPDENGNPVNVCSEQSRALQVGCSLANIDPFANLPGTIVVASLNAKGTRASYSS
CEEEEECCCCCCCCCEECCCCCCEEEECCEEECCCCCCCCCCEEEEEEECCCCCCCCCCC
TGSALWVSGLGGEFGRQRKFYPDAASTFFPDSAPYAYDPAIVTTDLSGCTAGENVEDPDV
CCCEEEEECCCCCCCCCCCCCCCCHHHCCCCCCCCEECCEEEEECCCCCCCCCCCCCHHH
VYNALDGSKSKIDASCNYNAIMNGTSAAAPTVSGVAALILGANASLSARDVKYILATTAR
EEECCCCCCCEEECCCCCCEEECCCCCCCCHHHHHEEEEECCCCCCCHHHHEEEEEHHHH
QIDPWQPRVVYQGSVIDPGWITNAAGHRFSNWYGFGLADAAAAVYKARYFTPLPPMRDTQ
CCCCCCCEEEEECCEECCCCCCCCCCCCCCCEECCCHHHHHHHHHHHHCCCCCCCCCCCC
WVSSTDAASQIGGPARPGKLRIRVQQAMKVEAVQLSLQSAHKTPSNLRVVLVSPSGTRSV
CCCCCCHHHHCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCEE
VATPFSVLDPAAYAQTGFYIDLTSSNAFLDEKSRGIWTLEVTDMTDPRSTVALNAFKLRI
EECCHHHHCCHHHHCCCEEEEECCCCCEECCCCCCEEEEEEECCCCCCCEEEEEEEEEEE
VGH
ECC
>Mature Secondary Structure
MNSLRRRPLALLIAVLLTGGTPLSVLAATQATAATTPATTSAKAKATGNDPLLRYQWHIS
CCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCEEEECCCCCEEEEEEEEC
NQGQAVIGDSRPVAGVDMDVDILHALDIRGRGVRVGVVDDGLELGHEDLADNILPNGSHN
CCCCEEECCCCCCCCCCCCCEEEEEECCCCCCEEEEEECCCHHCCHHHHHHHCCCCCCCC
FGDGSHDTTPIDPSNGHGTSVAGIIGAVGWNGRGGRGVAPEVQLAGFDVFARDSSVTDAS
CCCCCCCCCCCCCCCCCCCCHHHHHEECCCCCCCCCCCCCCEEEECEEEEECCCCCCCCE
IRYAWGDGPEARNIDVFNNSWGSVAPFYFDFSVEDQRTWQALMGSTRGGLGGIYVKSAGN
EEEEECCCCCCCEEEEEECCCCCCCCEEEEEECCHHHHHHHHHCCCCCCCCEEEEECCCC
SFLRFLEPDENGNPVNVCSEQSRALQVGCSLANIDPFANLPGTIVVASLNAKGTRASYSS
CEEEEECCCCCCCCCEECCCCCCEEEECCEEECCCCCCCCCCEEEEEEECCCCCCCCCCC
TGSALWVSGLGGEFGRQRKFYPDAASTFFPDSAPYAYDPAIVTTDLSGCTAGENVEDPDV
CCCEEEEECCCCCCCCCCCCCCCCHHHCCCCCCCCEECCEEEEECCCCCCCCCCCCCHHH
VYNALDGSKSKIDASCNYNAIMNGTSAAAPTVSGVAALILGANASLSARDVKYILATTAR
EEECCCCCCCEEECCCCCCEEECCCCCCCCHHHHHEEEEECCCCCCCHHHHEEEEEHHHH
QIDPWQPRVVYQGSVIDPGWITNAAGHRFSNWYGFGLADAAAAVYKARYFTPLPPMRDTQ
CCCCCCCEEEEECCEECCCCCCCCCCCCCCCEECCCHHHHHHHHHHHHCCCCCCCCCCCC
WVSSTDAASQIGGPARPGKLRIRVQQAMKVEAVQLSLQSAHKTPSNLRVVLVSPSGTRSV
CCCCCCHHHHCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCEE
VATPFSVLDPAAYAQTGFYIDLTSSNAFLDEKSRGIWTLEVTDMTDPRSTVALNAFKLRI
EECCHHHHCCHHHHCCCEEEEECCCCCEECCCCCCEEEEEEECCCCCCCEEEEEEEEEEE
VGH
ECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1468618 [H]