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The map label for this gene is asd [H]

Identifier: 21243450

GI number: 21243450

Start: 3184332

End: 3185357

Strand: Reverse

Name: asd [H]

Synonym: XAC2723

Alternate gene names: 21243450

Gene position: 3185357-3184332 (Counterclockwise)

Preceding gene: 21243451

Following gene: 21243449

Centisome position: 61.55

GC content: 66.08

Gene sequence:

>1026_bases
ATGAGCAACGAAAACCGTCGTTTCAACGTCGCGGTCGTGGGCGCCACCGGCGCTGTCGGCGAGACCATGCTGAGCATCCT
GGCCGAGCGCAACTTCCCGGTCGCCACCCTGTACGCACTGGCGTCGGCGCGCTCGGCCGGCGGGCAGGTGGAGTTCAATG
GCGGCAAGGTCGATGTGCTGGACCTGGCCGAGTTCGACCCCGCCGGCGTGGATATCGCGCTGTTCTCCGCAGGTGGCAGC
GTGTCCAAGGAATACGGCCCCAAGTTCGCCGCTGCCGGCGCGGTGGTGATCGATAACTCGTCGGCGTTCCGCTACGACGA
CGACGTGCCGCTGGTGGTCTCCGAGGTCAACCCTGAAGCGCTCAAGCAGCGCCCGCGCGGCATCGTCGCCAATCCCAATT
GCTCGACCATGCAGATGCTGGTGGCACTGGGCCCGATCCACCGCACCTACGGCATCGAGCGCATCAATGTGGCGACCTAC
CAGTCGGTCTCCGGCGGCGGGCGCTCGGCGATGGAAGAACTGGGCAAGCAGACCAGCGAGCTGCTGAGCTTCCAGGACAT
AGACCCGCAGCGGTTCCCGGTGCAGATCGCCTTCAACCTGATTCCGCACATCGACGACTTCCAGGACAACGGCTACACCA
AGGAAGAGATGAAGCTGGTCTGGGAAACCCGCAAGATCCTCGGCGACGACAGCATCCAGGTGAACCCCACCGCGGTGCGC
GTGCCGGTGTTCTATGGCCACTCCGAAGCCGTGGCGATCGAAACCCGCGACAAGATCACCGTGGAAGCGGCGCGCGCGCT
GCTGGCAGCATCGCCGGGCGTGGAAGTGGTGGACGAGCGCGCCCCCGGCGGCTACCCGACGCCGGTCACGCACGCCTCGG
GCAAGGACGCGGTGTTCGTCGGTCGCATCCGCGAAGACTTTTCGCACCCGCGTGGCCTGAACCTGTGGATCGTCTCCGAC
AACATCCGCAAGGGCGCCGCGCTCAACGCCGTGCAGTTGGCCGAACTGGTCGCACAGGAAGGCTGA

Upstream 100 bases:

>100_bases
TCTCGACCAAACGATAGGGAACCTCCGCGGCCAGCATTGGAGGTTCCCCGAACCCAGCGCGCAGTGCTTCCTCATTTCCC
CTTTCGATAAAGACAAACTC

Downstream 100 bases:

>100_bases
GGGTCGCGATAAAAGCGACCGCGCAGCCGCTATGCGGGCGTGGCCGGTGCAGGCATCACCCGGCCACAGCGGTGCCGAGC
GCGCCGTCCGCACCCGCATG

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MSNENRRFNVAVVGATGAVGETMLSILAERNFPVATLYALASARSAGGQVEFNGGKVDVLDLAEFDPAGVDIALFSAGGS
VSKEYGPKFAAAGAVVIDNSSAFRYDDDVPLVVSEVNPEALKQRPRGIVANPNCSTMQMLVALGPIHRTYGIERINVATY
QSVSGGGRSAMEELGKQTSELLSFQDIDPQRFPVQIAFNLIPHIDDFQDNGYTKEEMKLVWETRKILGDDSIQVNPTAVR
VPVFYGHSEAVAIETRDKITVEAARALLAASPGVEVVDERAPGGYPTPVTHASGKDAVFVGRIREDFSHPRGLNLWIVSD
NIRKGAALNAVQLAELVAQEG

Sequences:

>Translated_341_residues
MSNENRRFNVAVVGATGAVGETMLSILAERNFPVATLYALASARSAGGQVEFNGGKVDVLDLAEFDPAGVDIALFSAGGS
VSKEYGPKFAAAGAVVIDNSSAFRYDDDVPLVVSEVNPEALKQRPRGIVANPNCSTMQMLVALGPIHRTYGIERINVATY
QSVSGGGRSAMEELGKQTSELLSFQDIDPQRFPVQIAFNLIPHIDDFQDNGYTKEEMKLVWETRKILGDDSIQVNPTAVR
VPVFYGHSEAVAIETRDKITVEAARALLAASPGVEVVDERAPGGYPTPVTHASGKDAVFVGRIREDFSHPRGLNLWIVSD
NIRKGAALNAVQLAELVAQEG
>Mature_340_residues
SNENRRFNVAVVGATGAVGETMLSILAERNFPVATLYALASARSAGGQVEFNGGKVDVLDLAEFDPAGVDIALFSAGGSV
SKEYGPKFAAAGAVVIDNSSAFRYDDDVPLVVSEVNPEALKQRPRGIVANPNCSTMQMLVALGPIHRTYGIERINVATYQ
SVSGGGRSAMEELGKQTSELLSFQDIDPQRFPVQIAFNLIPHIDDFQDNGYTKEEMKLVWETRKILGDDSIQVNPTAVRV
PVFYGHSEAVAIETRDKITVEAARALLAASPGVEVVDERAPGGYPTPVTHASGKDAVFVGRIREDFSHPRGLNLWIVSDN
IRKGAALNAVQLAELVAQEG

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=335, Percent_Identity=40.2985074626866, Blast_Score=232, Evalue=3e-62,
Organism=Escherichia coli, GI1789841, Length=361, Percent_Identity=31.3019390581717, Blast_Score=108, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6320362, Length=391, Percent_Identity=28.6445012787724, Blast_Score=90, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 36556; Mature: 36424

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNENRRFNVAVVGATGAVGETMLSILAERNFPVATLYALASARSAGGQVEFNGGKVDVL
CCCCCCEEEEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEECCCEEEEE
DLAEFDPAGVDIALFSAGGSVSKEYGPKFAAAGAVVIDNSSAFRYDDDVPLVVSEVNPEA
EECCCCCCCCEEEEEECCCCCCHHHCCCCHHCCEEEEECCCCEEECCCCCEEEECCCHHH
LKQRPRGIVANPNCSTMQMLVALGPIHRTYGIERINVATYQSVSGGGRSAMEELGKQTSE
HHHCCCCEEECCCHHHHHHHHHHCCHHHHCCCEEEEEEEEECCCCCCHHHHHHHHHHHHH
LLSFQDIDPQRFPVQIAFNLIPHIDDFQDNGYTKEEMKLVWETRKILGDDSIQVNPTAVR
HHHHCCCCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEECCEEEE
VPVFYGHSEAVAIETRDKITVEAARALLAASPGVEVVDERAPGGYPTPVTHASGKDAVFV
EEEEECCCCEEEEECCCCCHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCCCEEEE
GRIREDFSHPRGLNLWIVSDNIRKGAALNAVQLAELVAQEG
EEHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
SNENRRFNVAVVGATGAVGETMLSILAERNFPVATLYALASARSAGGQVEFNGGKVDVL
CCCCCEEEEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEECCCEEEEE
DLAEFDPAGVDIALFSAGGSVSKEYGPKFAAAGAVVIDNSSAFRYDDDVPLVVSEVNPEA
EECCCCCCCCEEEEEECCCCCCHHHCCCCHHCCEEEEECCCCEEECCCCCEEEECCCHHH
LKQRPRGIVANPNCSTMQMLVALGPIHRTYGIERINVATYQSVSGGGRSAMEELGKQTSE
HHHCCCCEEECCCHHHHHHHHHHCCHHHHCCCEEEEEEEEECCCCCCHHHHHHHHHHHHH
LLSFQDIDPQRFPVQIAFNLIPHIDDFQDNGYTKEEMKLVWETRKILGDDSIQVNPTAVR
HHHHCCCCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEECCEEEE
VPVFYGHSEAVAIETRDKITVEAARALLAASPGVEVVDERAPGGYPTPVTHASGKDAVFV
EEEEECCCCEEEEECCCCCHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCCCEEEE
GRIREDFSHPRGLNLWIVSDNIRKGAALNAVQLAELVAQEG
EEHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9573067 [H]