Click here to switch to the map view.

The map label for this gene is aglA [H]

Identifier: 21243333

GI number: 21243333

Start: 3068749

End: 3070365

Strand: Reverse

Name: aglA [H]

Synonym: XAC2602

Alternate gene names: 21243333

Gene position: 3070365-3068749 (Counterclockwise)

Preceding gene: 21243336

Following gene: 21243332

Centisome position: 59.32

GC content: 62.4

Gene sequence:

>1617_bases
ATGTTGCAGACACCATGGTGGCGCGGGGCCGTCATCTATCAGATCTATCCGCGTAGCTTTCCGGATTCCAATGGCGATGG
GGTCGGCGATCTGCCGGGCATCATCGCCAAGCTCGACTACATCGCTGGGCTGGGCGTGGATGCCATCTGGATCTCGCCGT
TTTTCAAGTCGCCGATGGCAGATTTCGGCTATGACATCGCGGACTACCGTGCGGTGGATCCGTTGTTCGGAACGCTGGAC
GATTTCGACCGTCTGCTCGACAGGGCGCATGCGCTTGGCCTGAAGGTGATGATCGATCAGGTGTTGAGCCACACCTCGAT
CGAACATGCGTGGTTCCAGGAAAGCCGGCAGGACCGGACCAATGCGAAGGCGGATTGGTATGTGTGGGCCGATCCGCGCG
AGGACGGAACGCCGCCCAACAACTGGTTGTCGCTGTTCGGTGGTGTGGCGTGGCAGTGGGAGCCGCGGCGCGAGCAGTAC
TACCTGCATAACTTCCTGGTCGATCAGCCGGACCTCAATTTCCATAATGCGGAGGTGCAGCAGGCAACCCTGGACAATGT
GCGGTTCTGGTTGGATCGTGGAGTAGATGGCTTTCGCCTGGACGCGATCAACTTCTGCTTCCATGACGCGCAGCTGCGCG
ATAACCCGGCCAAGCCGGCCGACAAGCGGGTGGGGCGTGGCTTTAGCGCGGACAATCCGTACGCCTATCAGTACCACTAC
TTCAACAACACGCAGCCGGAGAACCTGGCGTTCCTGGAGCGCCTGCGTGCGCTGCTCGATCGCTATCCGGATGCGGTAAG
CCTGGGCGAAATCTCTTCGGAAGACTCGCTGGCGACCACGGCCGAATACACCGCCAAGGGCCGCTTGCACATGGGCTACA
GCTTCGAGCTGTTGGTGCAGGATTACAGCGCGGCGTACATCCGCGGAACGGTCAGCAGGCTCGAGGCCACCATGTTGGAA
GGATGGCCGTGCTGGGCCATTTCCAACCACGATGTGGTGCGTGCGGTGACGCGTTGGGGCGGTGAAGATGCGTCGCCTGC
GTTCGCTCGCATGGTAGTTGCGCTGCTATGTTCGTTGCGTGGCTCGGTTTGCCTGTACCAGGGCGAGGAGCTTGGGCTAG
GCGAGGCGGATGTGGCGTTCGAGGATCTGCGGGATCCGTACGGCATCACGTTCTGGCCGACCTTCAAGGGCCGCGATGGA
TGCCGTACGCCGATGCCGTGGACCGATGCGCCGTCGGCGGGTTTCACCAGCGGCAAGCCGTGGTTGCCGTTGTCCGAGCC
GCATCGTCTGGCTGCAGTGAGTGTGCAGCAGGACGATGCCCAGTCTGTGCTGCGCGCAGTGCGGGCATTTCTGAGTTGGC
GCAGGAGCATGCCGGCCCTGCTCGAAGGGGCGATCGCGTTCTACGACATCGCAGAGCCGGTGCTGATGTTCCGGCGTGAG
CATGCGGGCCAGGTCATGCTGTTGGCGTTCAATTTGTCTGCAGACATCACCGAGCTGGCACTGCCTGCGGGTGCATGGCG
CCAGATCGATGTGCCGGGGGTGGAGCGTGGCGTGATCGAGCATGGCCGCGTGCGCTTGCCGGGGCATGCTGTGGTTTGCG
CAATGGGCGGGCAGTGA

Upstream 100 bases:

>100_bases
TACGTATGCACGTCCGCGCCCAAAGAGTGCCACGCCGCTAGGCTAACGCCCTTAGTCGGTGGCCGTGTTGGCTGCCAGCA
GTGGCCCGGGAGGGGCGTGC

Downstream 100 bases:

>100_bases
CGCGGTCGCTTCACAGAGAGCTTTATGAGCATGTTTGATTGATACCGGCGAGACATCGTCGAACAACGGCTGGCTGACCC
ACACCCTGGCGCGACGGCCG

Product: alpha-glucosidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 538; Mature: 538

Protein sequence:

>538_residues
MLQTPWWRGAVIYQIYPRSFPDSNGDGVGDLPGIIAKLDYIAGLGVDAIWISPFFKSPMADFGYDIADYRAVDPLFGTLD
DFDRLLDRAHALGLKVMIDQVLSHTSIEHAWFQESRQDRTNAKADWYVWADPREDGTPPNNWLSLFGGVAWQWEPRREQY
YLHNFLVDQPDLNFHNAEVQQATLDNVRFWLDRGVDGFRLDAINFCFHDAQLRDNPAKPADKRVGRGFSADNPYAYQYHY
FNNTQPENLAFLERLRALLDRYPDAVSLGEISSEDSLATTAEYTAKGRLHMGYSFELLVQDYSAAYIRGTVSRLEATMLE
GWPCWAISNHDVVRAVTRWGGEDASPAFARMVVALLCSLRGSVCLYQGEELGLGEADVAFEDLRDPYGITFWPTFKGRDG
CRTPMPWTDAPSAGFTSGKPWLPLSEPHRLAAVSVQQDDAQSVLRAVRAFLSWRRSMPALLEGAIAFYDIAEPVLMFRRE
HAGQVMLLAFNLSADITELALPAGAWRQIDVPGVERGVIEHGRVRLPGHAVVCAMGGQ

Sequences:

>Translated_538_residues
MLQTPWWRGAVIYQIYPRSFPDSNGDGVGDLPGIIAKLDYIAGLGVDAIWISPFFKSPMADFGYDIADYRAVDPLFGTLD
DFDRLLDRAHALGLKVMIDQVLSHTSIEHAWFQESRQDRTNAKADWYVWADPREDGTPPNNWLSLFGGVAWQWEPRREQY
YLHNFLVDQPDLNFHNAEVQQATLDNVRFWLDRGVDGFRLDAINFCFHDAQLRDNPAKPADKRVGRGFSADNPYAYQYHY
FNNTQPENLAFLERLRALLDRYPDAVSLGEISSEDSLATTAEYTAKGRLHMGYSFELLVQDYSAAYIRGTVSRLEATMLE
GWPCWAISNHDVVRAVTRWGGEDASPAFARMVVALLCSLRGSVCLYQGEELGLGEADVAFEDLRDPYGITFWPTFKGRDG
CRTPMPWTDAPSAGFTSGKPWLPLSEPHRLAAVSVQQDDAQSVLRAVRAFLSWRRSMPALLEGAIAFYDIAEPVLMFRRE
HAGQVMLLAFNLSADITELALPAGAWRQIDVPGVERGVIEHGRVRLPGHAVVCAMGGQ
>Mature_538_residues
MLQTPWWRGAVIYQIYPRSFPDSNGDGVGDLPGIIAKLDYIAGLGVDAIWISPFFKSPMADFGYDIADYRAVDPLFGTLD
DFDRLLDRAHALGLKVMIDQVLSHTSIEHAWFQESRQDRTNAKADWYVWADPREDGTPPNNWLSLFGGVAWQWEPRREQY
YLHNFLVDQPDLNFHNAEVQQATLDNVRFWLDRGVDGFRLDAINFCFHDAQLRDNPAKPADKRVGRGFSADNPYAYQYHY
FNNTQPENLAFLERLRALLDRYPDAVSLGEISSEDSLATTAEYTAKGRLHMGYSFELLVQDYSAAYIRGTVSRLEATMLE
GWPCWAISNHDVVRAVTRWGGEDASPAFARMVVALLCSLRGSVCLYQGEELGLGEADVAFEDLRDPYGITFWPTFKGRDG
CRTPMPWTDAPSAGFTSGKPWLPLSEPHRLAAVSVQQDDAQSVLRAVRAFLSWRRSMPALLEGAIAFYDIAEPVLMFRRE
HAGQVMLLAFNLSADITELALPAGAWRQIDVPGVERGVIEHGRVRLPGHAVVCAMGGQ

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=455, Percent_Identity=35.6043956043956, Blast_Score=278, Evalue=7e-75,
Organism=Escherichia coli, GI1790687, Length=527, Percent_Identity=36.6223908918406, Blast_Score=306, Evalue=2e-84,
Organism=Escherichia coli, GI1786604, Length=495, Percent_Identity=23.8383838383838, Blast_Score=84, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI32565753, Length=485, Percent_Identity=25.979381443299, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI25147709, Length=530, Percent_Identity=23.3962264150943, Blast_Score=101, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6321731, Length=553, Percent_Identity=34.5388788426763, Blast_Score=291, Evalue=3e-79,
Organism=Saccharomyces cerevisiae, GI6319776, Length=553, Percent_Identity=34.5388788426763, Blast_Score=290, Evalue=3e-79,
Organism=Saccharomyces cerevisiae, GI6322245, Length=568, Percent_Identity=33.2746478873239, Blast_Score=290, Evalue=4e-79,
Organism=Saccharomyces cerevisiae, GI6321726, Length=553, Percent_Identity=32.7305605786618, Blast_Score=274, Evalue=2e-74,
Organism=Saccharomyces cerevisiae, GI6322241, Length=555, Percent_Identity=32.6126126126126, Blast_Score=265, Evalue=2e-71,
Organism=Saccharomyces cerevisiae, GI6322021, Length=555, Percent_Identity=32.6126126126126, Blast_Score=265, Evalue=2e-71,
Organism=Saccharomyces cerevisiae, GI6324416, Length=555, Percent_Identity=32.6126126126126, Blast_Score=263, Evalue=4e-71,
Organism=Drosophila melanogaster, GI24586591, Length=520, Percent_Identity=37.1153846153846, Blast_Score=310, Evalue=1e-84,
Organism=Drosophila melanogaster, GI24583745, Length=520, Percent_Identity=37.3076923076923, Blast_Score=308, Evalue=8e-84,
Organism=Drosophila melanogaster, GI24586599, Length=520, Percent_Identity=35.7692307692308, Blast_Score=304, Evalue=8e-83,
Organism=Drosophila melanogaster, GI24583749, Length=515, Percent_Identity=36.8932038834951, Blast_Score=303, Evalue=3e-82,
Organism=Drosophila melanogaster, GI24583747, Length=515, Percent_Identity=36.8932038834951, Blast_Score=302, Evalue=4e-82,
Organism=Drosophila melanogaster, GI24586597, Length=507, Percent_Identity=36.2919132149901, Blast_Score=299, Evalue=3e-81,
Organism=Drosophila melanogaster, GI24586587, Length=498, Percent_Identity=36.3453815261044, Blast_Score=299, Evalue=4e-81,
Organism=Drosophila melanogaster, GI24586593, Length=498, Percent_Identity=36.5461847389558, Blast_Score=292, Evalue=4e-79,
Organism=Drosophila melanogaster, GI24586589, Length=520, Percent_Identity=35.9615384615385, Blast_Score=286, Evalue=3e-77,
Organism=Drosophila melanogaster, GI221330053, Length=507, Percent_Identity=34.7140039447732, Blast_Score=285, Evalue=5e-77,
Organism=Drosophila melanogaster, GI45549022, Length=526, Percent_Identity=32.1292775665399, Blast_Score=280, Evalue=1e-75,
Organism=Drosophila melanogaster, GI281360393, Length=445, Percent_Identity=33.2584269662921, Blast_Score=218, Evalue=7e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.20 [H]

Molecular weight: Translated: 60507; Mature: 60507

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQTPWWRGAVIYQIYPRSFPDSNGDGVGDLPGIIAKLDYIAGLGVDAIWISPFFKSPMA
CCCCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECHHHCCCHH
DFGYDIADYRAVDPLFGTLDDFDRLLDRAHALGLKVMIDQVLSHTSIEHAWFQESRQDRT
HHCCCHHHHHHHCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCC
NAKADWYVWADPREDGTPPNNWLSLFGGVAWQWEPRREQYYLHNFLVDQPDLNFHNAEVQ
CCCCCEEEEECCCCCCCCHHHHHHHHCCCEEEECCCHHHHHHHHHEECCCCCCCCCCHHH
QATLDNVRFWLDRGVDGFRLDAINFCFHDAQLRDNPAKPADKRVGRGFSADNPYAYQYHY
HHHHHHHHHHHHCCCCCEEEHHHHHHEECCHHCCCCCCCHHHHHCCCCCCCCCEEEEEEE
FNNTQPENLAFLERLRALLDRYPDAVSLGEISSEDSLATTAEYTAKGRLHMGYSFELLVQ
CCCCCCHHHHHHHHHHHHHHHCCCCEECCCCCCCCCHHHHHHHHCCCEEEECCEEEEEEE
DYSAAYIRGTVSRLEATMLEGWPCWAISNHDVVRAVTRWGGEDASPAFARMVVALLCSLR
HHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHC
GSVCLYQGEELGLGEADVAFEDLRDPYGITFWPTFKGRDGCRTPMPWTDAPSAGFTSGKP
CCEEEEECCCCCCCCHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCC
WLPLSEPHRLAAVSVQQDDAQSVLRAVRAFLSWRRSMPALLEGAIAFYDIAEPVLMFRRE
CCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
HAGQVMLLAFNLSADITELALPAGAWRQIDVPGVERGVIEHGRVRLPGHAVVCAMGGQ
CCCEEEEEEEECCCCHHHHHCCCCCCEEECCCCCHHHHHCCCCEECCCCEEEEEECCC
>Mature Secondary Structure
MLQTPWWRGAVIYQIYPRSFPDSNGDGVGDLPGIIAKLDYIAGLGVDAIWISPFFKSPMA
CCCCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECHHHCCCHH
DFGYDIADYRAVDPLFGTLDDFDRLLDRAHALGLKVMIDQVLSHTSIEHAWFQESRQDRT
HHCCCHHHHHHHCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCC
NAKADWYVWADPREDGTPPNNWLSLFGGVAWQWEPRREQYYLHNFLVDQPDLNFHNAEVQ
CCCCCEEEEECCCCCCCCHHHHHHHHCCCEEEECCCHHHHHHHHHEECCCCCCCCCCHHH
QATLDNVRFWLDRGVDGFRLDAINFCFHDAQLRDNPAKPADKRVGRGFSADNPYAYQYHY
HHHHHHHHHHHHCCCCCEEEHHHHHHEECCHHCCCCCCCHHHHHCCCCCCCCCEEEEEEE
FNNTQPENLAFLERLRALLDRYPDAVSLGEISSEDSLATTAEYTAKGRLHMGYSFELLVQ
CCCCCCHHHHHHHHHHHHHHHCCCCEECCCCCCCCCHHHHHHHHCCCEEEECCEEEEEEE
DYSAAYIRGTVSRLEATMLEGWPCWAISNHDVVRAVTRWGGEDASPAFARMVVALLCSLR
HHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHC
GSVCLYQGEELGLGEADVAFEDLRDPYGITFWPTFKGRDGCRTPMPWTDAPSAGFTSGKP
CCEEEEECCCCCCCCHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCC
WLPLSEPHRLAAVSVQQDDAQSVLRAVRAFLSWRRSMPALLEGAIAFYDIAEPVLMFRRE
CCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
HAGQVMLLAFNLSADITELALPAGAWRQIDVPGVERGVIEHGRVRLPGHAVVCAMGGQ
CCCEEEEEEEECCCCHHHHHCCCCCCEEECCCCCHHHHHCCCCEECCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10400573; 11481430 [H]