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The map label for this gene is fabH [H]

Identifier: 21243303

GI number: 21243303

Start: 3030577

End: 3031575

Strand: Reverse

Name: fabH [H]

Synonym: XAC2571

Alternate gene names: 21243303

Gene position: 3031575-3030577 (Counterclockwise)

Preceding gene: 21243304

Following gene: 21243302

Centisome position: 58.57

GC content: 68.47

Gene sequence:

>999_bases
TTGAACGCATTGCCGCTGCGCATCCTGGGCACCGGGCGCCATGTTCCGGCGACGGAAGTGACATCGCACCAGTTGGACGA
GCGCTGGCAGTTGCCGGCCGGAACAACGTTCGCGCGTCTGGGTGTGCAGACGCGCCATTACGTGGGCGAGGGCGAAACCG
CATCGTCGATGGGGGCAGCCGCTGCGCAACAGGCCGTGGCCAGCGCCGGGCTCGATGCCAGTCGGATCGATTGCCTGATC
TCCGCCTGCAGCGTCATGGAGCAGCCGATTCCCTGCCAGGCGGTGTTGATCCAACGCGCGCTCGGCCTCGGCGATTCGGG
CATCCCCGCATTCGACGTCAATGCCACCTGCCTGAGTTTCCTGGTTGCCCTGGATATGGCGGCCAACGCACTGGCGCTAG
GCCGGTACGAGTGCGTGCTGATCGTCTCCAGCGAAGTCGCATCGGCCGGGCTGGACGCAGCGACGCCGGCCACGGCCGGC
TTGTTCGGCGATGGCGCAGCCGCGGTGGTCGTTGGCCGCAGCGACGCAGGGCAGGGCTCGGCGCTGCTCTCCAGCCGGCT
GTCCAGTTATGGCAATGGCGCGGAGCTGTGCCGCATTCGCGGCGGCGGCACGCGTTATCCGCACGGCGAAGACAGCGCGC
CCGATGCTTCGCGCGTGTTCTGCATGGACGGACGCGGCGCCTACCGTTTCGCCGCGCGGCATCTGCCAGCGTTCTGGGAA
CAGCTGCTGCACGAGGCCGGCATCGCCGCCGCAGCGTTGCGCTGCCTGGTACCGCACCAGGCCTCCGGTGGCGGCCTGGA
TCATGTGGTGCAGACCTTGGGACTGCGCCCCGATCAGGTGGTGCGCATCCTGCAGACCACCGGTAATCAGGTTGCCGCGT
CGTTGCCGCATGCGTTGCATCAGGCACGCGTCGACCTGGGCCTGCAGCGCGGCGATCTGGTCGCGCTGCTTGGCACCGGG
GCAGGGCTTGCCATCGGCGGCATGGTGTTGCGCTACTGA

Upstream 100 bases:

>100_bases
TCGCGGTGCTTGCGCTTAGATGTGTATCGGCATGCATGGCGGTGGGCCTGCCGATGCGGCCACGGTATGCTGCGCGCCTT
CACGTTTTGAGAGCTGCGCG

Downstream 100 bases:

>100_bases
TGCCGGTACGCGTGTCGCTCGAGCTGCTGCGCGTAGGCCACTGTCGCCATTGCGAACGCATGGTGCGCGCCGATGGTCAC
TGGCACGCGGTGGAATTCCC

Product: 3-oxoacyl-[ACP] synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MNALPLRILGTGRHVPATEVTSHQLDERWQLPAGTTFARLGVQTRHYVGEGETASSMGAAAAQQAVASAGLDASRIDCLI
SACSVMEQPIPCQAVLIQRALGLGDSGIPAFDVNATCLSFLVALDMAANALALGRYECVLIVSSEVASAGLDAATPATAG
LFGDGAAAVVVGRSDAGQGSALLSSRLSSYGNGAELCRIRGGGTRYPHGEDSAPDASRVFCMDGRGAYRFAARHLPAFWE
QLLHEAGIAAAALRCLVPHQASGGGLDHVVQTLGLRPDQVVRILQTTGNQVAASLPHALHQARVDLGLQRGDLVALLGTG
AGLAIGGMVLRY

Sequences:

>Translated_332_residues
MNALPLRILGTGRHVPATEVTSHQLDERWQLPAGTTFARLGVQTRHYVGEGETASSMGAAAAQQAVASAGLDASRIDCLI
SACSVMEQPIPCQAVLIQRALGLGDSGIPAFDVNATCLSFLVALDMAANALALGRYECVLIVSSEVASAGLDAATPATAG
LFGDGAAAVVVGRSDAGQGSALLSSRLSSYGNGAELCRIRGGGTRYPHGEDSAPDASRVFCMDGRGAYRFAARHLPAFWE
QLLHEAGIAAAALRCLVPHQASGGGLDHVVQTLGLRPDQVVRILQTTGNQVAASLPHALHQARVDLGLQRGDLVALLGTG
AGLAIGGMVLRY
>Mature_332_residues
MNALPLRILGTGRHVPATEVTSHQLDERWQLPAGTTFARLGVQTRHYVGEGETASSMGAAAAQQAVASAGLDASRIDCLI
SACSVMEQPIPCQAVLIQRALGLGDSGIPAFDVNATCLSFLVALDMAANALALGRYECVLIVSSEVASAGLDAATPATAG
LFGDGAAAVVVGRSDAGQGSALLSSRLSSYGNGAELCRIRGGGTRYPHGEDSAPDASRVFCMDGRGAYRFAARHLPAFWE
QLLHEAGIAAAALRCLVPHQASGGGLDHVVQTLGLRPDQVVRILQTTGNQVAASLPHALHQARVDLGLQRGDLVALLGTG
AGLAIGGMVLRY

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=326, Percent_Identity=30.6748466257669, Blast_Score=137, Evalue=8e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.41 [H]

Molecular weight: Translated: 34164; Mature: 34164

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNALPLRILGTGRHVPATEVTSHQLDERWQLPAGTTFARLGVQTRHYVGEGETASSMGAA
CCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCHHHHHCCHHHHCCCCCCCHHHHHHH
AAQQAVASAGLDASRIDCLISACSVMEQPIPCQAVLIQRALGLGDSGIPAFDVNATCLSF
HHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCEECCCHHHHHH
LVALDMAANALALGRYECVLIVSSEVASAGLDAATPATAGLFGDGAAAVVVGRSDAGQGS
HHHHHHHHHHHEECCEEEEEEEECHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCH
ALLSSRLSSYGNGAELCRIRGGGTRYPHGEDSAPDASRVFCMDGRGAYRFAARHLPAFWE
HHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHH
QLLHEAGIAAAALRCLVPHQASGGGLDHVVQTLGLRPDQVVRILQTTGNQVAASLPHALH
HHHHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHH
QARVDLGLQRGDLVALLGTGAGLAIGGMVLRY
HHHHHHCCCCCCEEEEEECCCCHHHHHHHHCC
>Mature Secondary Structure
MNALPLRILGTGRHVPATEVTSHQLDERWQLPAGTTFARLGVQTRHYVGEGETASSMGAA
CCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCHHHHHCCHHHHCCCCCCCHHHHHHH
AAQQAVASAGLDASRIDCLISACSVMEQPIPCQAVLIQRALGLGDSGIPAFDVNATCLSF
HHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCEECCCHHHHHH
LVALDMAANALALGRYECVLIVSSEVASAGLDAATPATAGLFGDGAAAVVVGRSDAGQGS
HHHHHHHHHHHEECCEEEEEEEECHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCH
ALLSSRLSSYGNGAELCRIRGGGTRYPHGEDSAPDASRVFCMDGRGAYRFAARHLPAFWE
HHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHH
QLLHEAGIAAAALRCLVPHQASGGGLDHVVQTLGLRPDQVVRILQTTGNQVAASLPHALH
HHHHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHH
QARVDLGLQRGDLVALLGTGAGLAIGGMVLRY
HHHHHHCCCCCCEEEEEECCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA