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The map label for this gene is kdgR [H]

Identifier: 21243233

GI number: 21243233

Start: 2923216

End: 2924211

Strand: Reverse

Name: kdgR [H]

Synonym: XAC2500

Alternate gene names: 21243233

Gene position: 2924211-2923216 (Counterclockwise)

Preceding gene: 77748658

Following gene: 21243229

Centisome position: 56.5

GC content: 68.27

Gene sequence:

>996_bases
GTGAGTATCAGCATCAATGACGTGGCCCGCGTGGCCGGCGTATCCAAGTCCACGGTGTCGCGCGCGCTGGGCAGCGGCCC
TGTCAGCGACGAGGTACGGGCCAAGGTGGAAGCGGCGGTGCGCCAGACCGGCTATCGGCCCAACCTGATGGCGCGTCGAT
TGCGATCCCAGCAATCCGGCATCCTGGGGGTGATCGTGGCCGACATCCGCAACCCGTACTTCACGGCGCTGATCCGTGCG
GTGGAAGAGGTCGCCTACAAGGCCGGTATGCGCGTGACCCTGTGCAATACCGATGAAGATCCCGAGCGCGAGGCGTTATA
CCTGGAGCTGATGCAGGAAGAACGCATCACCGGGCTGATTTTTGCGCCGACCCGCGTCACGGTGGGGCGCATGCACGAGC
TGGCGCTGGATTACCCCACCGTGCTGGTTGACCGCGCCGGCCCTGGCAGCCGTTATGACAGCGTCGTGCTGGACAACGGC
GCGGCCATGGCCGAGCTGGTGGCGCATCTGCAGGCGCAGGGCTATCGGCGCATCGGCGGGCTGTTCGGCAGCACCAGCAC
CACCGCGGCCGAGCGCCGCGACGGCTACCTGGCAGCGATGCGCGCACAGGGGCTGCAGCCGGATTACCGCGAAGTGGCGC
CTACCGCCGAGGCGGCGATCGCCGAGCTGGGGGCATGGCTGGCCAACGACCGGCGGCCCGAGGCCATCGTCACCAGTAAC
AGCCTGCTGCTGATGGGCGCACTGAAGGCCGCACGCACCGCCGGCCTGCGCCTGCCGCAGGATCTGGCCCTGGCCGGGTT
CGACAACGAGCGCTGGACCGATCTGGTCGAGCCGGGCATCACCGTGGTCGAGCAGCCGGTGGAAGACATGGGCCGGGCGG
CGATGTCGCTGCTGCTGGAACGGCTAAGCAATCCGCAATTGCCGATCCGCCGCATGGTGATGACAGGACGCTGCGTGGTG
CGTGGGTCGACCGGCGCGCGTATTGCGGGCGTGTAG

Upstream 100 bases:

>100_bases
AATGTGCGGTGCACAAAAACGCTGTAGTGCTTTCGGGTTAGCATCAGGGCCGACACCGCGCCTGGGTCAAGGTGCGCAAA
ATGGAGCGGGAACGGTCCCA

Downstream 100 bases:

>100_bases
GGCGGTGGCTTTTGGGTGCGGTGGCTTTAACGGTCATGCGTTCGCGCCCGGGTGCGCTCCTACAAGGATGGTTGTCTGCC
GCGCGTTGCGGACCTGCACG

Product: LacI family transcription regulator

Products: NA

Alternate protein names: Kdg operon repressor [H]

Number of amino acids: Translated: 331; Mature: 330

Protein sequence:

>331_residues
MSISINDVARVAGVSKSTVSRALGSGPVSDEVRAKVEAAVRQTGYRPNLMARRLRSQQSGILGVIVADIRNPYFTALIRA
VEEVAYKAGMRVTLCNTDEDPEREALYLELMQEERITGLIFAPTRVTVGRMHELALDYPTVLVDRAGPGSRYDSVVLDNG
AAMAELVAHLQAQGYRRIGGLFGSTSTTAAERRDGYLAAMRAQGLQPDYREVAPTAEAAIAELGAWLANDRRPEAIVTSN
SLLLMGALKAARTAGLRLPQDLALAGFDNERWTDLVEPGITVVEQPVEDMGRAAMSLLLERLSNPQLPIRRMVMTGRCVV
RGSTGARIAGV

Sequences:

>Translated_331_residues
MSISINDVARVAGVSKSTVSRALGSGPVSDEVRAKVEAAVRQTGYRPNLMARRLRSQQSGILGVIVADIRNPYFTALIRA
VEEVAYKAGMRVTLCNTDEDPEREALYLELMQEERITGLIFAPTRVTVGRMHELALDYPTVLVDRAGPGSRYDSVVLDNG
AAMAELVAHLQAQGYRRIGGLFGSTSTTAAERRDGYLAAMRAQGLQPDYREVAPTAEAAIAELGAWLANDRRPEAIVTSN
SLLLMGALKAARTAGLRLPQDLALAGFDNERWTDLVEPGITVVEQPVEDMGRAAMSLLLERLSNPQLPIRRMVMTGRCVV
RGSTGARIAGV
>Mature_330_residues
SISINDVARVAGVSKSTVSRALGSGPVSDEVRAKVEAAVRQTGYRPNLMARRLRSQQSGILGVIVADIRNPYFTALIRAV
EEVAYKAGMRVTLCNTDEDPEREALYLELMQEERITGLIFAPTRVTVGRMHELALDYPTVLVDRAGPGSRYDSVVLDNGA
AMAELVAHLQAQGYRRIGGLFGSTSTTAAERRDGYLAAMRAQGLQPDYREVAPTAEAAIAELGAWLANDRRPEAIVTSNS
LLLMGALKAARTAGLRLPQDLALAGFDNERWTDLVEPGITVVEQPVEDMGRAAMSLLLERLSNPQLPIRRMVMTGRCVVR
GSTGARIAGV

Specific function: Transcriptional repressor of the kdg operon for pectin utilization [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790194, Length=332, Percent_Identity=32.5301204819277, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI1790369, Length=329, Percent_Identity=31.6109422492401, Blast_Score=160, Evalue=8e-41,
Organism=Escherichia coli, GI1788474, Length=312, Percent_Identity=33.6538461538462, Blast_Score=138, Evalue=5e-34,
Organism=Escherichia coli, GI1787948, Length=316, Percent_Identity=30.0632911392405, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI1789202, Length=331, Percent_Identity=31.7220543806647, Blast_Score=131, Evalue=7e-32,
Organism=Escherichia coli, GI1787906, Length=333, Percent_Identity=29.7297297297297, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1789068, Length=301, Percent_Identity=29.5681063122924, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1787580, Length=330, Percent_Identity=29.0909090909091, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1786268, Length=321, Percent_Identity=25.5451713395639, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI48994940, Length=307, Percent_Identity=30.6188925081433, Blast_Score=95, Evalue=8e-21,
Organism=Escherichia coli, GI1790689, Length=313, Percent_Identity=28.1150159744409, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1790715, Length=312, Percent_Identity=27.8846153846154, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1786540, Length=306, Percent_Identity=26.4705882352941, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1789456, Length=335, Percent_Identity=24.1791044776119, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012310
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 35790; Mature: 35658

Theoretical pI: Translated: 8.18; Mature: 8.18

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSISINDVARVAGVSKSTVSRALGSGPVSDEVRAKVEAAVRQTGYRPNLMARRLRSQQSG
CCCCHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCC
ILGVIVADIRNPYFTALIRAVEEVAYKAGMRVTLCNTDEDPEREALYLELMQEERITGLI
EEEEEEEHHCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHCCCCEEE
FAPTRVTVGRMHELALDYPTVLVDRAGPGSRYDSVVLDNGAAMAELVAHLQAQGYRRIGG
EECCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEECCHHHHHHHHHHHHCCHHHHHH
LFGSTSTTAAERRDGYLAAMRAQGLQPDYREVAPTAEAAIAELGAWLANDRRPEAIVTSN
HCCCCCCHHHHHHCCHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHHHHCCCCCCEEEECC
SLLLMGALKAARTAGLRLPQDLALAGFDNERWTDLVEPGITVVEQPVEDMGRAAMSLLLE
CCHHHHHHHHHHHHCCCCCHHHEEECCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
RLSNPQLPIRRMVMTGRCVVRGSTGARIAGV
HHCCCCCHHHHHHHCCCEEEECCCCCEECCC
>Mature Secondary Structure 
SISINDVARVAGVSKSTVSRALGSGPVSDEVRAKVEAAVRQTGYRPNLMARRLRSQQSG
CCCHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCC
ILGVIVADIRNPYFTALIRAVEEVAYKAGMRVTLCNTDEDPEREALYLELMQEERITGLI
EEEEEEEHHCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHCCCCEEE
FAPTRVTVGRMHELALDYPTVLVDRAGPGSRYDSVVLDNGAAMAELVAHLQAQGYRRIGG
EECCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEECCHHHHHHHHHHHHCCHHHHHH
LFGSTSTTAAERRDGYLAAMRAQGLQPDYREVAPTAEAAIAELGAWLANDRRPEAIVTSN
HCCCCCCHHHHHHCCHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHHHHCCCCCCEEEECC
SLLLMGALKAARTAGLRLPQDLALAGFDNERWTDLVEPGITVVEQPVEDMGRAAMSLLLE
CCHHHHHHHHHHHHCCCCCHHHEEECCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
RLSNPQLPIRRMVMTGRCVVRGSTGARIAGV
HHCCCCCHHHHHHHCCCEEEECCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]