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The map label for this gene is ydeP [H]

Identifier: 21243219

GI number: 21243219

Start: 2894567

End: 2896915

Strand: Reverse

Name: ydeP [H]

Synonym: XAC2486

Alternate gene names: 21243219

Gene position: 2896915-2894567 (Counterclockwise)

Preceding gene: 21243220

Following gene: 21243218

Centisome position: 55.97

GC content: 64.88

Gene sequence:

>2349_bases
ATGAGCAAGAAAACCATCAAGCAGTACGACAATCCCGCGGGCGGCTGGGGCGCATTGCGCTCGGTGGCCAAGCACCTGAT
GGAACAGGACATCGCCGTGCAGGGCGCCAAGACGCTGCTGCACGCCAACCAGCCGGACGGCTTCGACTGCCCCGGTTGCG
CCTGGCCGGATCGCGACCATACGTCCACCTTCGAATTCTGCGAAAACGGCGCCAAGGCCGTGGCGGCCGAGTCCACCGCA
CGTCGCGCCGGGCCGGAGCTGTTCGCTTCGCACACCGTCAGCCTGCTGTCGCAATACAGCGACTACTGGCTGGAAGGGCA
GGGTCGACTGACCCACCCGATGCGCTACGACGCTGCGAGCGATCACTACGTGCCGGTGAGCTGGGACGATGCCTTTGCGC
AGATCGCGCGGCATCTCAATGGCCTGGCAACGCCGGATGAGGCGATCTTCTACACCTCCGGGCGTACCAGCAACGAGGCA
GCGTTCTTGTATCAGTTGTTCGTGCGCGAGTTCGGCACCAACAACTTCCCCGATTGCTCCAACATGTGCCACGAGCCCTC
CGGCACGGCGCTGCGTTCGCAGATCGGCGTGGGCAAGGGCACGGTGTCGCTGCACGATTTCGAGCTGGCCGACGCCATCT
TCATCTTCGGGCAGAACCCGGGCACCAATCACCCGCGGATGCTGGGCGAGTTGCGTCAGGCCTCCAAGCGCGGTGCGGCG
ATTGCGGCGTTCAACCCGCTGCGCGAGCGCGGGCTGGAAAAGTTCGCCGACCCCCAGGACAAGCTGGAGATGTTGCACAA
CGGTTCCACGCGCATCGCTTCGGATTATTTCCAGCTCAAGATCGGCGGCGACCTGGCTGCGGTGAAGGGCATCATCAAGC
ATGTGCTGGAGCGCGATGCGCAGGCGCAGCGCGATGGTACGCCGCGCTTGCTGGACCTGGAGTTCATCCAGGCGCACACC
GCCAATTTCGAGGCCTTCGCTGCCGACGTGCATGCGGAAAGCTGGGACACCATCGTCGAAGAATCCGGGCTGGACGAAAC
TGCGCTGCGCAAAGCCGGCGAGATCTATCTCAATGCCGAGCGCGTGATTGCCTGCTGGGGCATGGGGATCACCCAGCACA
AGCATTCGGTGGCGACCATCCACATGATCACCAACCTGCTGCTGCTGCGCGGCAACCTGGGCCGTCCCGGCGCGGGCGTC
TGCCCGGTGCGCGGGCACAGCAACGTGCAGGGCGACCGCACGATGATGATCTATGAAAAGCCGCCGGCCGCGTTCCTGGA
CAAGCTGCAATCGGTGTTCGGTTTCGCGCCGCCACGCGCAGACGGGTTCGATACCGTGGGTGCGATCGAGGCGATGCTGG
ATGGGCGCGGCAAGGTGTTCTTCGCGATGGGTGGCAACTTTGCTGCCGCCACGCCGGATACCGATGCCACGCACCGCGCG
TTGCGCAACTGCGAATTGACCGTGCATGTCACCACCAAGCTCAATCGCAGCCACTTGGTGCATGGGCGCGATGCGTTGAT
CCTGCCGTGTTTGGGGCGCACCGAGATCGACATCCAGGATGCCGGCTCGCAAGGCGTGACGGTGGAAGATTCGATGAGCA
TGGTGCACCTGTCGGCCGGCATCAATCCGCCGGCCTCGCCGGACCTGCTGTCGGAGCCGGCGATCGTGGCGCGCATGGCC
GAAGCCACGTTGGGCGCACGCAGCGCGATCCGCTGGCGTTGGCTGGTAGGCGATTACGACCGCGTGCGCGATCTCATCGC
GCAGGTGTTCCCGGACTTTGCCGGTTTCAACGAGCGCGTGCGTACGCCGGGTGGGTTCCGTCTGTCCAACACCGCCCGCG
ATCGCCAGTGGGTGACGCCGGAACAACGCGCGGTGTTCAAGCCGCATGCGGTGCCCACCGACAACCCCATCCATCGCGCG
CGTCGTGGCCACGCCGAGCAGATGGTGTTTACGCTGGCCACCACGCGTTCGCACGATCAATACAACACCACCATTTATGG
GTTGGACGACCGCTATCGCGGCGTGTTCGGCGAGCGCCGTGTGCTGTTCATCAATGGGGCGGACATCGCGGCATTGAACA
TGAAGGCGGGCGATTGGGTTGACCTGGAAAGCCTGTGCGAGGACGGCGTGCGCCGCGAGGCGCGGCGTTTCCTGTTGGTG
GACTACAACATCCCGCGCGGCTGCCTGGCCGCGTACTACCCGGAAACCAACGCGCTGGTGCCGTTGTCCAGTTTCGCCGA
CGAGGCGCGTACGCCGACCTCCAAGTCGATTCCGGTGATCGTGCTGCCGCACCGCGCCGAAACCGCTGATGCGGCACCGC
GCGATATCGGAGCGGTGCTTGTCCGCTGA

Upstream 100 bases:

>100_bases
GTGCGGGACTGACCCTGATCGGGTTTGCCCGCGATCACGATTGTGTCGTTTACAGCCATCCGCAGCGCCTGGATCTGGGC
GTTGCCGTGGGAGAGCCCGC

Downstream 100 bases:

>100_bases
TCCACAGCTCACCGTGCAGCTGCTGCGTGTGCTTGCCGACGCGCCCGATGGCGTGTCGCTGGCGCGGCTATGCAAGCACC
TGGGCGTGCGGATGAGCGTG

Product: formate dehydrogenase a chain

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 782; Mature: 781

Protein sequence:

>782_residues
MSKKTIKQYDNPAGGWGALRSVAKHLMEQDIAVQGAKTLLHANQPDGFDCPGCAWPDRDHTSTFEFCENGAKAVAAESTA
RRAGPELFASHTVSLLSQYSDYWLEGQGRLTHPMRYDAASDHYVPVSWDDAFAQIARHLNGLATPDEAIFYTSGRTSNEA
AFLYQLFVREFGTNNFPDCSNMCHEPSGTALRSQIGVGKGTVSLHDFELADAIFIFGQNPGTNHPRMLGELRQASKRGAA
IAAFNPLRERGLEKFADPQDKLEMLHNGSTRIASDYFQLKIGGDLAAVKGIIKHVLERDAQAQRDGTPRLLDLEFIQAHT
ANFEAFAADVHAESWDTIVEESGLDETALRKAGEIYLNAERVIACWGMGITQHKHSVATIHMITNLLLLRGNLGRPGAGV
CPVRGHSNVQGDRTMMIYEKPPAAFLDKLQSVFGFAPPRADGFDTVGAIEAMLDGRGKVFFAMGGNFAAATPDTDATHRA
LRNCELTVHVTTKLNRSHLVHGRDALILPCLGRTEIDIQDAGSQGVTVEDSMSMVHLSAGINPPASPDLLSEPAIVARMA
EATLGARSAIRWRWLVGDYDRVRDLIAQVFPDFAGFNERVRTPGGFRLSNTARDRQWVTPEQRAVFKPHAVPTDNPIHRA
RRGHAEQMVFTLATTRSHDQYNTTIYGLDDRYRGVFGERRVLFINGADIAALNMKAGDWVDLESLCEDGVRREARRFLLV
DYNIPRGCLAAYYPETNALVPLSSFADEARTPTSKSIPVIVLPHRAETADAAPRDIGAVLVR

Sequences:

>Translated_782_residues
MSKKTIKQYDNPAGGWGALRSVAKHLMEQDIAVQGAKTLLHANQPDGFDCPGCAWPDRDHTSTFEFCENGAKAVAAESTA
RRAGPELFASHTVSLLSQYSDYWLEGQGRLTHPMRYDAASDHYVPVSWDDAFAQIARHLNGLATPDEAIFYTSGRTSNEA
AFLYQLFVREFGTNNFPDCSNMCHEPSGTALRSQIGVGKGTVSLHDFELADAIFIFGQNPGTNHPRMLGELRQASKRGAA
IAAFNPLRERGLEKFADPQDKLEMLHNGSTRIASDYFQLKIGGDLAAVKGIIKHVLERDAQAQRDGTPRLLDLEFIQAHT
ANFEAFAADVHAESWDTIVEESGLDETALRKAGEIYLNAERVIACWGMGITQHKHSVATIHMITNLLLLRGNLGRPGAGV
CPVRGHSNVQGDRTMMIYEKPPAAFLDKLQSVFGFAPPRADGFDTVGAIEAMLDGRGKVFFAMGGNFAAATPDTDATHRA
LRNCELTVHVTTKLNRSHLVHGRDALILPCLGRTEIDIQDAGSQGVTVEDSMSMVHLSAGINPPASPDLLSEPAIVARMA
EATLGARSAIRWRWLVGDYDRVRDLIAQVFPDFAGFNERVRTPGGFRLSNTARDRQWVTPEQRAVFKPHAVPTDNPIHRA
RRGHAEQMVFTLATTRSHDQYNTTIYGLDDRYRGVFGERRVLFINGADIAALNMKAGDWVDLESLCEDGVRREARRFLLV
DYNIPRGCLAAYYPETNALVPLSSFADEARTPTSKSIPVIVLPHRAETADAAPRDIGAVLVR
>Mature_781_residues
SKKTIKQYDNPAGGWGALRSVAKHLMEQDIAVQGAKTLLHANQPDGFDCPGCAWPDRDHTSTFEFCENGAKAVAAESTAR
RAGPELFASHTVSLLSQYSDYWLEGQGRLTHPMRYDAASDHYVPVSWDDAFAQIARHLNGLATPDEAIFYTSGRTSNEAA
FLYQLFVREFGTNNFPDCSNMCHEPSGTALRSQIGVGKGTVSLHDFELADAIFIFGQNPGTNHPRMLGELRQASKRGAAI
AAFNPLRERGLEKFADPQDKLEMLHNGSTRIASDYFQLKIGGDLAAVKGIIKHVLERDAQAQRDGTPRLLDLEFIQAHTA
NFEAFAADVHAESWDTIVEESGLDETALRKAGEIYLNAERVIACWGMGITQHKHSVATIHMITNLLLLRGNLGRPGAGVC
PVRGHSNVQGDRTMMIYEKPPAAFLDKLQSVFGFAPPRADGFDTVGAIEAMLDGRGKVFFAMGGNFAAATPDTDATHRAL
RNCELTVHVTTKLNRSHLVHGRDALILPCLGRTEIDIQDAGSQGVTVEDSMSMVHLSAGINPPASPDLLSEPAIVARMAE
ATLGARSAIRWRWLVGDYDRVRDLIAQVFPDFAGFNERVRTPGGFRLSNTARDRQWVTPEQRAVFKPHAVPTDNPIHRAR
RGHAEQMVFTLATTRSHDQYNTTIYGLDDRYRGVFGERRVLFINGADIAALNMKAGDWVDLESLCEDGVRREARRFLLVD
YNIPRGCLAAYYPETNALVPLSSFADEARTPTSKSIPVIVLPHRAETADAAPRDIGAVLVR

Specific function: Probably involved in acid resistance [H]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787778, Length=763, Percent_Identity=49.6723460026212, Blast_Score=768, Evalue=0.0,
Organism=Escherichia coli, GI3868721, Length=395, Percent_Identity=28.1012658227848, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1788534, Length=413, Percent_Identity=22.5181598062954, Blast_Score=86, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR010046 [H]

Pfam domain/function: PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: NA

Molecular weight: Translated: 85964; Mature: 85833

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKKTIKQYDNPAGGWGALRSVAKHLMEQDIAVQGAKTLLHANQPDGFDCPGCAWPDRDH
CCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHEECCCCCCCCCCCCCCCCCCC
TSTFEFCENGAKAVAAESTARRAGPELFASHTVSLLSQYSDYWLEGQGRLTHPMRYDAAS
CHHHHHHHCCCCEEHHHHHHHHCCHHHHHHHHHHHHHHHHHHEECCCCCCCCCEECCCCC
DHYVPVSWDDAFAQIARHLNGLATPDEAIFYTSGRTSNEAAFLYQLFVREFGTNNFPDCS
CCEEECCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCHH
NMCHEPSGTALRSQIGVGKGTVSLHDFELADAIFIFGQNPGTNHPRMLGELRQASKRGAA
HHCCCCCCCHHHHHCCCCCCEEEEEEEEEEEEEEEEECCCCCCCHHHHHHHHHHHHCCCE
IAAFNPLRERGLEKFADPQDKLEMLHNGSTRIASDYFQLKIGGDLAAVKGIIKHVLERDA
EEECCHHHHHHHHHHCCHHHHHHHHHCCCCEEECCEEEEEECCCHHHHHHHHHHHHHHHH
QAQRDGTPRLLDLEFIQAHTANFEAFAADVHAESWDTIVEESGLDETALRKAGEIYLNAE
HHHCCCCCCEEEHHHHHHHCCCCHHEEEHHCCCHHHHHHHHCCCCHHHHHCCCCEEEECC
RVIACWGMGITQHKHSVATIHMITNLLLLRGNLGRPGAGVCPVRGHSNVQGDRTMMIYEK
EEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEC
PPAAFLDKLQSVFGFAPPRADGFDTVGAIEAMLDGRGKVFFAMGGNFAAATPDTDATHRA
CCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCEEECCCCCHHHHHH
LRNCELTVHVTTKLNRSHLVHGRDALILPCLGRTEIDIQDAGSQGVTVEDSMSMVHLSAG
HHCCEEEEEEEEECCCHHEECCCCEEEEECCCCCEEEEECCCCCCCEEECCCCEEEEECC
INPPASPDLLSEPAIVARMAEATLGARSAIRWRWLVGDYDRVRDLIAQVFPDFAGFNERV
CCCCCCCCHHCCCHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCHHC
RTPGGFRLSNTARDRQWVTPEQRAVFKPHAVPTDNPIHRARRGHAEQMVFTLATTRSHDQ
CCCCCEEECCCCCCCCCCCCCHHCEECCCCCCCCCHHHHHHCCCHHHEEEEEEECCCCCC
YNTTIYGLDDRYRGVFGERRVLFINGADIAALNMKAGDWVDLESLCEDGVRREARRFLLV
CCCEEEECCHHHHCCCCCCEEEEEECCCEEEEECCCCCCCCHHHHHHHHHHHHHCEEEEE
DYNIPRGCLAAYYPETNALVPLSSFADEARTPTSKSIPVIVLPHRAETADAAPRDIGAVL
ECCCCCHHHEEECCCCCCEEECHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCCCEE
VR
CC
>Mature Secondary Structure 
SKKTIKQYDNPAGGWGALRSVAKHLMEQDIAVQGAKTLLHANQPDGFDCPGCAWPDRDH
CCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHEECCCCCCCCCCCCCCCCCCC
TSTFEFCENGAKAVAAESTARRAGPELFASHTVSLLSQYSDYWLEGQGRLTHPMRYDAAS
CHHHHHHHCCCCEEHHHHHHHHCCHHHHHHHHHHHHHHHHHHEECCCCCCCCCEECCCCC
DHYVPVSWDDAFAQIARHLNGLATPDEAIFYTSGRTSNEAAFLYQLFVREFGTNNFPDCS
CCEEECCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCHH
NMCHEPSGTALRSQIGVGKGTVSLHDFELADAIFIFGQNPGTNHPRMLGELRQASKRGAA
HHCCCCCCCHHHHHCCCCCCEEEEEEEEEEEEEEEEECCCCCCCHHHHHHHHHHHHCCCE
IAAFNPLRERGLEKFADPQDKLEMLHNGSTRIASDYFQLKIGGDLAAVKGIIKHVLERDA
EEECCHHHHHHHHHHCCHHHHHHHHHCCCCEEECCEEEEEECCCHHHHHHHHHHHHHHHH
QAQRDGTPRLLDLEFIQAHTANFEAFAADVHAESWDTIVEESGLDETALRKAGEIYLNAE
HHHCCCCCCEEEHHHHHHHCCCCHHEEEHHCCCHHHHHHHHCCCCHHHHHCCCCEEEECC
RVIACWGMGITQHKHSVATIHMITNLLLLRGNLGRPGAGVCPVRGHSNVQGDRTMMIYEK
EEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEC
PPAAFLDKLQSVFGFAPPRADGFDTVGAIEAMLDGRGKVFFAMGGNFAAATPDTDATHRA
CCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCEEECCCCCHHHHHH
LRNCELTVHVTTKLNRSHLVHGRDALILPCLGRTEIDIQDAGSQGVTVEDSMSMVHLSAG
HHCCEEEEEEEEECCCHHEECCCCEEEEECCCCCEEEEECCCCCCCEEECCCCEEEEECC
INPPASPDLLSEPAIVARMAEATLGARSAIRWRWLVGDYDRVRDLIAQVFPDFAGFNERV
CCCCCCCCHHCCCHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCHHC
RTPGGFRLSNTARDRQWVTPEQRAVFKPHAVPTDNPIHRARRGHAEQMVFTLATTRSHDQ
CCCCCEEECCCCCCCCCCCCCHHCEECCCCCCCCCHHHHHHCCCHHHEEEEEEECCCCCC
YNTTIYGLDDRYRGVFGERRVLFINGADIAALNMKAGDWVDLESLCEDGVRREARRFLLV
CCCEEEECCHHHHCCCCCCEEEEEECCCEEEEECCCCCCCCHHHHHHHHHHHHHCEEEEE
DYNIPRGCLAAYYPETNALVPLSSFADEARTPTSKSIPVIVLPHRAETADAAPRDIGAVL
ECCCCCHHHEEECCCCCCEEECHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCCCEE
VR
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]