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The map label for this gene is oprN [H]

Identifier: 21243206

GI number: 21243206

Start: 2877981

End: 2879489

Strand: Reverse

Name: oprN [H]

Synonym: XAC2473

Alternate gene names: 21243206

Gene position: 2879489-2877981 (Counterclockwise)

Preceding gene: 21243207

Following gene: 21243205

Centisome position: 55.64

GC content: 68.92

Gene sequence:

>1509_bases
TTGCAATGCACTGATTCCATGCGCCTGATCCGCATGCCGCTGGCTGCGGCGTTGAGTACGCTGCTGCTTGGCGGCTGCAT
GCTCGGCCCCAACTACACCAAGCCGCCAGCGGTTGCCGACGCGGCGATGCGAGCACCCGCCCTGCACCGCGCCAGCGGCG
CGGACGTGGTTGCCGCCGCACCCCTGAATCACTGGTGGGAGGAACTGCACGATCCGCTCCTGACACAATTGGTCGCCCAG
GCGTTGGCCGATAGCCCCAACCTGCGCGCGGCGCAGGCGCGGCTGCGCGCCAACCGCGCGCTGGCCCAGCAACGCCGCGC
CGAACGCCTGCCCAAGCTCAACGCCAGCGCGGTGTATGCCTACGCCGAGCCGCCGCAGACCATCGTCGATACGCTCGGCG
GGCTGCAACAGGGTCAACCCGGCCAGCCGCCGGCGGCCGGCAACCAGGCGTTGGATCTGGAAAAGACCGAGATTTACAGC
GCCGGTTTCGATGCCAGCTGGGAGCTGGATTTCTTCGGCCGCCGCCGTCGCGCCGCCGAAGGTGCGCTGGCGCAGGCGCA
GGCCTCCGAGGCCGAGCTCGCCGATGCGCAAGTGCAGCTGGCCGCCGAAGTCGGGCAGGTTTATCTCAACTACCGCGGCT
TGCAGGCGCGCCTGGCCATTGCCGATGCCAACCTGGACAAGATCCGCCAGTCGCTGCAGCTGGTGCAGCAACGCCGCGGG
CAGGGCGCCGCCTCGGACCTGCAGGTCGAGCAGATCGCCACCCAGGTGCAGCAACAGCAAGCCCAGCGCCTGCCGCTGGA
AATGCAATCGCAGGAGGCGCTGGACCAGCTGGCATTGATGGTCGGGCGCGAGCCCGGCGCGCTGGATGCGCAGCTCAGCG
CGCCGCAACCTTTGCCGATGTTGCCGACACAGGTCCGCGTGGACGATGCCGGTGCGTTGATCCGCCGGCGCCCGGACGTG
CGCAAGGCCGAGCGCGAGTTGGCCGCCTCCAGCGCGCAGATCGGCGAAGCGTTGAACGGCTACTTCCCGCAGGTGAGTCT
GCTGGGCGGGTTGAGCTGGGTCGCCGGCTCGCCGAGCGATTTCAATTCCGATGCGCGGACCACATTGGCGGTGCCGATGC
TGCGCTGGTCGATCTTCGACTTCGGCAAGACCCGCGCGCAGGTGGAGCAGGCGCGCGCCGGCAATGCCGGTCGTACGGCG
GCGTACGAAGGGACCGTGTTGGCGGCCTTGCAGGATGCCAATTCGGCCTTGGCGCGCTTCGGTTCGGCACGCAAACAATT
GGTGGTCGCACGCCAGGCCGAAGCCTCGGCCACGCGTTCGGCCGGGCTGATGCAGCAACGTCGCGATGCCGGCGCCACCT
CATCGATCGATCTGCTGGATGTGCAGCGCCAGCAGTTGTCGGCGCAGGACGCCGCCGCGCAGGCGCAGGTGCAGTTGCTG
GTGAATTACGTGGCCCTGCAGAAGAGTCTGGGGCTGGGCTGGAGCGAACCGGCGCAGGACGCGCGCTGA

Upstream 100 bases:

>100_bases
GTGATGACCTATAGCGATCTGTTCTGGATCTTCGGCGTGATCGTGGTCTGCACGATTCCGCTGGCCTTTTTGCTCAAGCC
GTTACCCAAGGGGGCGCACC

Downstream 100 bases:

>100_bases
GACCAGCCAAGGCAATCGTTGACGCGGCAGCTCATGCGCGGCCGCGTCCCGGTTTTGCCATCATGGTCGGCATTGGCCGT
TGTGGCGCATGCATTGCGCA

Product: outer membrane protein OprN

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 502; Mature: 502

Protein sequence:

>502_residues
MQCTDSMRLIRMPLAAALSTLLLGGCMLGPNYTKPPAVADAAMRAPALHRASGADVVAAAPLNHWWEELHDPLLTQLVAQ
ALADSPNLRAAQARLRANRALAQQRRAERLPKLNASAVYAYAEPPQTIVDTLGGLQQGQPGQPPAAGNQALDLEKTEIYS
AGFDASWELDFFGRRRRAAEGALAQAQASEAELADAQVQLAAEVGQVYLNYRGLQARLAIADANLDKIRQSLQLVQQRRG
QGAASDLQVEQIATQVQQQQAQRLPLEMQSQEALDQLALMVGREPGALDAQLSAPQPLPMLPTQVRVDDAGALIRRRPDV
RKAERELAASSAQIGEALNGYFPQVSLLGGLSWVAGSPSDFNSDARTTLAVPMLRWSIFDFGKTRAQVEQARAGNAGRTA
AYEGTVLAALQDANSALARFGSARKQLVVARQAEASATRSAGLMQQRRDAGATSSIDLLDVQRQQLSAQDAAAQAQVQLL
VNYVALQKSLGLGWSEPAQDAR

Sequences:

>Translated_502_residues
MQCTDSMRLIRMPLAAALSTLLLGGCMLGPNYTKPPAVADAAMRAPALHRASGADVVAAAPLNHWWEELHDPLLTQLVAQ
ALADSPNLRAAQARLRANRALAQQRRAERLPKLNASAVYAYAEPPQTIVDTLGGLQQGQPGQPPAAGNQALDLEKTEIYS
AGFDASWELDFFGRRRRAAEGALAQAQASEAELADAQVQLAAEVGQVYLNYRGLQARLAIADANLDKIRQSLQLVQQRRG
QGAASDLQVEQIATQVQQQQAQRLPLEMQSQEALDQLALMVGREPGALDAQLSAPQPLPMLPTQVRVDDAGALIRRRPDV
RKAERELAASSAQIGEALNGYFPQVSLLGGLSWVAGSPSDFNSDARTTLAVPMLRWSIFDFGKTRAQVEQARAGNAGRTA
AYEGTVLAALQDANSALARFGSARKQLVVARQAEASATRSAGLMQQRRDAGATSSIDLLDVQRQQLSAQDAAAQAQVQLL
VNYVALQKSLGLGWSEPAQDAR
>Mature_502_residues
MQCTDSMRLIRMPLAAALSTLLLGGCMLGPNYTKPPAVADAAMRAPALHRASGADVVAAAPLNHWWEELHDPLLTQLVAQ
ALADSPNLRAAQARLRANRALAQQRRAERLPKLNASAVYAYAEPPQTIVDTLGGLQQGQPGQPPAAGNQALDLEKTEIYS
AGFDASWELDFFGRRRRAAEGALAQAQASEAELADAQVQLAAEVGQVYLNYRGLQARLAIADANLDKIRQSLQLVQQRRG
QGAASDLQVEQIATQVQQQQAQRLPLEMQSQEALDQLALMVGREPGALDAQLSAPQPLPMLPTQVRVDDAGALIRRRPDV
RKAERELAASSAQIGEALNGYFPQVSLLGGLSWVAGSPSDFNSDARTTLAVPMLRWSIFDFGKTRAQVEQARAGNAGRTA
AYEGTVLAALQDANSALARFGSARKQLVVARQAEASATRSAGLMQQRRDAGATSSIDLLDVQRQQLSAQDAAAQAQVQLL
VNYVALQKSLGLGWSEPAQDAR

Specific function: The outer membrane component of an organic solvent efflux pump. Involved in export of a number of low log POW compounds including hexane (log POW 3.5), toluene (log POW 2.5) and dimethylphthalate (log POW 2.3). The solvent resistance phenotype has been po

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786785, Length=494, Percent_Identity=26.3157894736842, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI2367348, Length=507, Percent_Identity=24.4575936883629, Blast_Score=78, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 53804; Mature: 53804

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQCTDSMRLIRMPLAAALSTLLLGGCMLGPNYTKPPAVADAAMRAPALHRASGADVVAAA
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCHHHCCCCCCEEEEC
PLNHWWEELHDPLLTQLVAQALADSPNLRAAQARLRANRALAQQRRAERLPKLNASAVYA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
YAEPPQTIVDTLGGLQQGQPGQPPAAGNQALDLEKTEIYSAGFDASWELDFFGRRRRAAE
ECCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCEEHHHHHHHHHHHH
GALAQAQASEAELADAQVQLAAEVGQVYLNYRGLQARLAIADANLDKIRQSLQLVQQRRG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHCC
QGAASDLQVEQIATQVQQQQAQRLPLEMQSQEALDQLALMVGREPGALDAQLSAPQPLPM
CCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
LPTQVRVDDAGALIRRRPDVRKAERELAASSAQIGEALNGYFPQVSLLGGLSWVAGSPSD
CCCEEEECCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCHHHHCCCCCC
FNSDARTTLAVPMLRWSIFDFGKTRAQVEQARAGNAGRTAAYEGTVLAALQDANSALARF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCEEEEHHHHHHHHHHHH
GSARKQLVVARQAEASATRSAGLMQQRRDAGATSSIDLLDVQRQQLSAQDAAAQAQVQLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VNYVALQKSLGLGWSEPAQDAR
HHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MQCTDSMRLIRMPLAAALSTLLLGGCMLGPNYTKPPAVADAAMRAPALHRASGADVVAAA
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCHHHCCCCCCEEEEC
PLNHWWEELHDPLLTQLVAQALADSPNLRAAQARLRANRALAQQRRAERLPKLNASAVYA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
YAEPPQTIVDTLGGLQQGQPGQPPAAGNQALDLEKTEIYSAGFDASWELDFFGRRRRAAE
ECCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCEEHHHHHHHHHHHH
GALAQAQASEAELADAQVQLAAEVGQVYLNYRGLQARLAIADANLDKIRQSLQLVQQRRG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHCC
QGAASDLQVEQIATQVQQQQAQRLPLEMQSQEALDQLALMVGREPGALDAQLSAPQPLPM
CCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
LPTQVRVDDAGALIRRRPDVRKAERELAASSAQIGEALNGYFPQVSLLGGLSWVAGSPSD
CCCEEEECCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCHHHHCCCCCC
FNSDARTTLAVPMLRWSIFDFGKTRAQVEQARAGNAGRTAAYEGTVLAALQDANSALARF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCEEEEHHHHHHHHHHHH
GSARKQLVVARQAEASATRSAGLMQQRRDAGATSSIDLLDVQRQQLSAQDAAAQAQVQLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VNYVALQKSLGLGWSEPAQDAR
HHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9417051; 9852029 [H]